| Aak1 (AAK1) | NAK | Other | 7lvh | A | | n-[3-methoxy-4-(1,3-oxazol-5-yl)phenyl]-d-leucinamide | Mouse | 13820 | |
| Aak1 (AAK1) | NAK | Other | 7lvi | A | A | (2r,3r)-n-[3-methoxy-4-(1,3-oxazol-5-yl)phenyl]-3-(propan-2-yl)piperidine-2-carboxamide | Mouse | 13822 | |
| Aak1 (AAK1) | NAK | Other | 7lvi | A | B | (2r,3r)-n-[3-methoxy-4-(1,3-oxazol-5-yl)phenyl]-3-(propan-2-yl)piperidine-2-carboxamide | Mouse | 13821 | |
| Aak1 (AAK1) | NAK | Other | 7rj6 | A | A | 5-[(4-aminopiperidin-1-yl)methyl]-n-{3-[5-(propan-2-yl)-1,3,4-thiadiazol-2-yl]phenyl}pyrrolo[2,1-f][1,2,4]triazin-4-amine | Mouse | 14132 | |
| Aak1 (AAK1) | NAK | Other | 7rj6 | A | B | 5-[(4-aminopiperidin-1-yl)methyl]-n-{3-[5-(propan-2-yl)-1,3,4-thiadiazol-2-yl]phenyl}pyrrolo[2,1-f][1,2,4]triazin-4-amine | Mouse | 14131 | |
| Aak1 (AAK1) | NAK | Other | 7rj7 | A | A | 2-[(1s)-1-amino-3-methylbutyl]-6-(pyridin-4-yl)quinoline-4-carbonitrile | Mouse | 14128 | |
| Aak1 (AAK1) | NAK | Other | 7rj7 | A | B | 2-[(1s)-1-amino-3-methylbutyl]-6-(pyridin-4-yl)quinoline-4-carbonitrile | Mouse | 14129 | |
| Aak1 (AAK1) | NAK | Other | 7rj8 | A | A | n-[3-(difluoromethoxy)-4-(1,3-oxazol-5-yl)phenyl]-d-leucinamide | Mouse | 14130 | |
| Aak1 (AAK1) | NAK | Other | 7rj8 | A | B | n-[3-(difluoromethoxy)-4-(1,3-oxazol-5-yl)phenyl]-d-leucinamide | Mouse | 14127 | |
| AAK1 | NAK | Other | 4wsq | A | A | k-252a | Human | 3834 | |
| AAK1 | NAK | Other | 4wsq | A | B | k-252a | Human | 3836 | |
| AAK1 | NAK | Other | 4wsq | B | A | k-252a | Human | 3833 | |
| AAK1 | NAK | Other | 4wsq | B | B | k-252a | Human | 3835 | |
| AAK1 | NAK | Other | 5l4q | A | A | ~{n}-[5-(4-cyanophenyl)-1~{h}-pyrrolo[2,3-b]pyridin-3-yl]pyridine-3-carboxamide | Human | 6679 | |
| AAK1 | NAK | Other | 5l4q | A | B | ~{n}-[5-(4-cyanophenyl)-1~{h}-pyrrolo[2,3-b]pyridin-3-yl]pyridine-3-carboxamide | Human | 6677 | |
| AAK1 | NAK | Other | 5l4q | B | A | ~{n}-[5-(4-cyanophenyl)-1~{h}-pyrrolo[2,3-b]pyridin-3-yl]pyridine-3-carboxamide | Human | 6680 | |
| AAK1 | NAK | Other | 5l4q | B | B | ~{n}-[5-(4-cyanophenyl)-1~{h}-pyrrolo[2,3-b]pyridin-3-yl]pyridine-3-carboxamide | Human | 6678 | |
| AAK1 | NAK | Other | 5te0 | A | | methyl (3z)-3-{[(4-{methyl[(4-methylpiperazin-1-yl)acetyl]amino}phenyl)amino](phenyl)methylidene}-2-oxo-2,3-dihydro-1h-indole-6-carboxylate | Human | 7156 | |
| AAK1 | NAK | Other | 8gmc | A | | 5-[(4-aminopiperidin-1-yl)methyl]-n-{3-[5-(propan-2-yl)-1,3,4-thiadiazol-2-yl]phenyl}pyrrolo[2,1-f][1,2,4]triazin-4-amine | Human | 14843 | |
| AAK1 | NAK | Other | 8gmd | A | | (5p)-3-({(8r)-5-[(4-aminopiperidin-1-yl)methyl]pyrrolo[2,1-f][1,2,4]triazin-4-yl}amino)-5-[2-(propan-2-yl)-2h-tetrazol-5-yl]phenol | Human | 14844 | |
| Abl1 (ABL1) | Abl | TK | 1fpu | A | | n-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-3-pyridinecarboxamide | Mouse | 5728 | |
| Abl1 (ABL1) | Abl | TK | 1fpu | B | | n-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-3-pyridinecarboxamide | Mouse | 5705 | |
| Abl1 (ABL1) | Abl | TK | 1iep | A | | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Mouse | 5703 | |
| Abl1 (ABL1) | Abl | TK | 1iep | B | | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Mouse | 5727 | |
| Abl1 (ABL1) | Abl | TK | 1m52 | A | | 6-(2,6-dichloro-phenyl)-8-methyl-2-(3-methylsulfanyl-phenylamino)-8h-pyrido[2,3-d]pyrimidin-7-one | Mouse | 5720 | |
| Abl1 (ABL1) | Abl | TK | 1m52 | B | | 6-(2,6-dichloro-phenyl)-8-methyl-2-(3-methylsulfanyl-phenylamino)-8h-pyrido[2,3-d]pyrimidin-7-one | Mouse | 5715 | |
| Abl1 (ABL1) | Abl | TK | 1opj | A | | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Mouse | 5732 | |
| Abl1 (ABL1) | Abl | TK | 1opj | B | | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Mouse | 5736 | |
| Abl1 (ABL1) | Abl | TK | 1opk | A | | 6-(2,6-dichlorophenyl)-2-{[3-(hydroxymethyl)phenyl]amino}-8-methylpyrido[2,3-d]pyrimidin-7(8h)-one | Mouse | 5709 | |
| Abl1 (ABL1) | Abl | TK | 2hzn | A | | 1-[4-(pyridin-4-yloxy)phenyl]-3-[3-(trifluoromethyl)phenyl]urea | Mouse | 5701 | |
| Abl1 (ABL1) | Abl | TK | 2qoh | A | | 5-[3-(2-methoxyphenyl)-1h-pyrrolo[2,3-b]pyridin-5-yl]-n,n-dimethylpyridine-3-carboxamide | Mouse | 5707 | |
| Abl1 (ABL1) | Abl | TK | 2qoh | B | | 5-[3-(2-methoxyphenyl)-1h-pyrrolo[2,3-b]pyridin-5-yl]-n,n-dimethylpyridine-3-carboxamide | Mouse | 5716 | |
| Abl1 (ABL1) | Abl | TK | 2z60 | A | | 5-[3-(2-methoxyphenyl)-1h-pyrrolo[2,3-b]pyridin-5-yl]-n,n-dimethylpyridine-3-carboxamide | Mouse | 5735 | |
| Abl1 (ABL1) | Abl | TK | 3dk3 | A | A | 2-amino-5-[3-(1-ethyl-1h-pyrazol-5-yl)-1h-pyrrolo[2,3-b]pyridin-5-yl]-n,n-dimethylbenzamide | Mouse | 5726 | |
| Abl1 (ABL1) | Abl | TK | 3dk3 | A | B | 2-amino-5-[3-(1-ethyl-1h-pyrazol-5-yl)-1h-pyrrolo[2,3-b]pyridin-5-yl]-n,n-dimethylbenzamide | Mouse | 5729 | |
| Abl1 (ABL1) | Abl | TK | 3dk3 | B | A | 2-amino-5-[3-(1-ethyl-1h-pyrazol-5-yl)-1h-pyrrolo[2,3-b]pyridin-5-yl]-n,n-dimethylbenzamide | Mouse | 5712 | |
| Abl1 (ABL1) | Abl | TK | 3dk3 | B | B | 2-amino-5-[3-(1-ethyl-1h-pyrazol-5-yl)-1h-pyrrolo[2,3-b]pyridin-5-yl]-n,n-dimethylbenzamide | Mouse | 5737 | |
| Abl1 (ABL1) | Abl | TK | 3dk6 | A | | 2-amino-5-[3-(1-ethyl-1h-pyrazol-5-yl)-1h-pyrrolo[2,3-b]pyridin-5-yl]-n,n-dimethylbenzamide | Mouse | 5725 | |
| Abl1 (ABL1) | Abl | TK | 3dk6 | B | | 2-amino-5-[3-(1-ethyl-1h-pyrazol-5-yl)-1h-pyrrolo[2,3-b]pyridin-5-yl]-n,n-dimethylbenzamide | Mouse | 5718 | |
| Abl1 (ABL1) | Abl | TK | 3dk7 | A | | 2-amino-5-[3-(1-ethyl-1h-pyrazol-5-yl)-1h-pyrrolo[2,3-b]pyridin-5-yl]-n,n-dimethylbenzamide | Mouse | 5704 | |
| Abl1 (ABL1) | Abl | TK | 3dk7 | B | | 2-amino-5-[3-(1-ethyl-1h-pyrazol-5-yl)-1h-pyrrolo[2,3-b]pyridin-5-yl]-n,n-dimethylbenzamide | Mouse | 5714 | |
| Abl1 (ABL1) | Abl | TK | 3ik3 | A | | 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-n-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide | Mouse | 5731 | |
| Abl1 (ABL1) | Abl | TK | 3ik3 | B | | 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-n-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide | Mouse | 5739 | |
| Abl1 (ABL1) | Abl | TK | 3k5v | A | A | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Mouse | 5734 | |
| Abl1 (ABL1) | Abl | TK | 3k5v | A | B | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Mouse | 5723 | |
| Abl1 (ABL1) | Abl | TK | 3k5v | B | A | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Mouse | 5710 | |
| Abl1 (ABL1) | Abl | TK | 3k5v | B | B | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Mouse | 5722 | |
| Abl1 (ABL1) | Abl | TK | 3kf4 | A | | n-[4-(dimethylphosphoryl)phenyl]-9-[(e)-2-(5-methyl-1h-indazol-4-yl)ethenyl]-9h-purin-6-amine | Mouse | 5717 | |
| Abl1 (ABL1) | Abl | TK | 3kf4 | B | | n-[4-(dimethylphosphoryl)phenyl]-9-[(e)-2-(5-methyl-1h-indazol-4-yl)ethenyl]-9h-purin-6-amine | Mouse | 5741 | |
| Abl1 (ABL1) | Abl | TK | 3kfa | A | | 3-{(e)-2-[6-(cyclopropylamino)-9h-purin-9-yl]ethenyl}-4-methyl-n-[3-(4-methyl-1h-imidazol-1-yl)-5-(trifluoromethyl)phenyl]benzamide | Mouse | 5742 | |
| Abl1 (ABL1) | Abl | TK | 3kfa | B | | 3-{(e)-2-[6-(cyclopropylamino)-9h-purin-9-yl]ethenyl}-4-methyl-n-[3-(4-methyl-1h-imidazol-1-yl)-5-(trifluoromethyl)phenyl]benzamide | Mouse | 5740 | |
| Abl1 (ABL1) | Abl | TK | 3ms9 | A | A | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Mouse | 5733 | |
| Abl1 (ABL1) | Abl | TK | 3ms9 | A | B | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Mouse | 5708 | |
| Abl1 (ABL1) | Abl | TK | 3ms9 | B | A | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Mouse | 5713 | |
| Abl1 (ABL1) | Abl | TK | 3ms9 | B | B | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Mouse | 5706 | |
| Abl1 (ABL1) | Abl | TK | 3mss | A | | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Mouse | 5724 | |
| Abl1 (ABL1) | Abl | TK | 3mss | B | | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Mouse | 5730 | |
| Abl1 (ABL1) | Abl | TK | 3mss | C | | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Mouse | 5719 | |
| Abl1 (ABL1) | Abl | TK | 3mss | D | | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Mouse | 5702 | |
| Abl1 (ABL1) | Abl | TK | 3oxz | A | | 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-n-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide | Mouse | 5721 | |
| Abl1 (ABL1) | Abl | TK | 3oy3 | A | | 5-[(5-{[4-{[4-(2-hydroxyethyl)piperazin-1-yl]methyl}-3-(trifluoromethyl)phenyl]carbamoyl}-2-methylphenyl)ethynyl]-1-methyl-1h-imidazole-2-carboxamide | Mouse | 5711 | |
| Abl1 (ABL1) | Abl | TK | 3oy3 | B | | 5-[(5-{[4-{[4-(2-hydroxyethyl)piperazin-1-yl]methyl}-3-(trifluoromethyl)phenyl]carbamoyl}-2-methylphenyl)ethynyl]-1-methyl-1h-imidazole-2-carboxamide | Mouse | 5738 | |
| Abl1 (ABL1) | Abl | TK | 6hd4 | A | A | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Mouse | 10645 | |
| Abl1 (ABL1) | Abl | TK | 6hd4 | A | B | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Mouse | 10647 | |
| Abl1 (ABL1) | Abl | TK | 6hd4 | B | A | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Mouse | 10648 | |
| Abl1 (ABL1) | Abl | TK | 6hd4 | B | B | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Mouse | 10646 | |
| Abl1 (ABL1) | Abl | TK | 6hd6 | A | A | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Mouse | 10609 | |
| Abl1 (ABL1) | Abl | TK | 6hd6 | A | B | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Mouse | 10608 | |
| Abl1 (ABL1) | Abl | TK | 6hd6 | B | A | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Mouse | 10611 | |
| Abl1 (ABL1) | Abl | TK | 6hd6 | B | B | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Mouse | 10610 | |
| ABL1 | Abl | TK | 1opl | A | | 6-(2,6-dichlorophenyl)-2-{[3-(hydroxymethyl)phenyl]amino}-8-methylpyrido[2,3-d]pyrimidin-7(8h)-one | Human | 1104 | |
| ABL1 | Abl | TK | 1opl | B | | 6-(2,6-dichlorophenyl)-2-{[3-(hydroxymethyl)phenyl]amino}-8-methylpyrido[2,3-d]pyrimidin-7(8h)-one | Human | 1086 | |
| ABL1 | Abl | TK | 2e2b | A | | n-[3-(4,5'-bipyrimidin-2-ylamino)-4-methylphenyl]-4-{[(3s)-3-(dimethylamino)pyrrolidin-1-yl]methyl}-3-(trifluoromethyl)benzamide | Human | 1054 | |
| ABL1 | Abl | TK | 2e2b | B | | n-[3-(4,5'-bipyrimidin-2-ylamino)-4-methylphenyl]-4-{[(3s)-3-(dimethylamino)pyrrolidin-1-yl]methyl}-3-(trifluoromethyl)benzamide | Human | 1065 | |
| ABL1 | Abl | TK | 2f4j | A | | cyclopropanecarboxylic acid {4-[4-(4-methyl-piperazin-1-yl)-6-(5-methyl-2h-pyrazol-3-ylamino)-pyrimidin-2-ylsulfanyl]-phenyl}-amide | Human | 1090 | |
| ABL1 | Abl | TK | 2fo0 | A | | 6-(2,6-dichlorophenyl)-2-{[3-(hydroxymethyl)phenyl]amino}-8-methylpyrido[2,3-d]pyrimidin-7(8h)-one | Human | 1073 | |
| ABL1 | Abl | TK | 2g1t | A | | - | Human | 1045 | |
| ABL1 | Abl | TK | 2g1t | B | | - | Human | 1105 | |
| ABL1 | Abl | TK | 2g1t | C | | - | Human | 1064 | |
| ABL1 | Abl | TK | 2g1t | D | | - | Human | 1096 | |
| ABL1 | Abl | TK | 2g2f | A | | - | Human | 1097 | |
| ABL1 | Abl | TK | 2g2f | B | | phosphothiophosphoric acid-adenylate ester | Human | 1079 | |
| ABL1 | Abl | TK | 2g2h | A | | 6-(2,6-dichlorophenyl)-2-{[3-(hydroxymethyl)phenyl]amino}-8-methylpyrido[2,3-d]pyrimidin-7(8h)-one | Human | 1106 | |
| ABL1 | Abl | TK | 2g2h | B | | 6-(2,6-dichlorophenyl)-2-{[3-(hydroxymethyl)phenyl]amino}-8-methylpyrido[2,3-d]pyrimidin-7(8h)-one | Human | 1089 | |
| ABL1 | Abl | TK | 2g2i | A | | adenosine-5'-diphosphate | Human | 1111 | |
| ABL1 | Abl | TK | 2g2i | B | | adenosine-5'-diphosphate | Human | 1075 | |
| ABL1 | Abl | TK | 2gqg | A | A | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 1060 | |
| ABL1 | Abl | TK | 2gqg | A | B | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 1053 | |
| ABL1 | Abl | TK | 2gqg | B | A | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 1084 | |
| ABL1 | Abl | TK | 2gqg | B | B | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 1082 | |
| ABL1 | Abl | TK | 2hiw | A | | 7-amino-1-methyl-3-(2-methyl-5-{[3-(trifluoromethyl)benzoyl]amino}phenyl)-2-oxo-2,3-dihydropyrimido[4,5-d]pyrimidin-1-ium | Human | 1069 | |
| ABL1 | Abl | TK | 2hiw | B | | 7-amino-1-methyl-3-(2-methyl-5-{[3-(trifluoromethyl)benzoyl]amino}phenyl)-2-oxo-2,3-dihydropyrimido[4,5-d]pyrimidin-1-ium | Human | 1110 | |
| ABL1 | Abl | TK | 2hyy | A | | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Human | 1092 | |
| ABL1 | Abl | TK | 2hyy | B | | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Human | 1078 | |
| ABL1 | Abl | TK | 2hyy | C | | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Human | 1048 | |
| ABL1 | Abl | TK | 2hyy | D | | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Human | 1068 | |
| ABL1 | Abl | TK | 2hz0 | A | A | 2-{[(6-oxo-1,6-dihydropyridin-3-yl)methyl]amino}-n-[4-propyl-3-(trifluoromethyl)phenyl]benzamide | Human | 1052 | |
| ABL1 | Abl | TK | 2hz0 | A | B | 2-{[(6-oxo-1,6-dihydropyridin-3-yl)methyl]amino}-n-[4-propyl-3-(trifluoromethyl)phenyl]benzamide | Human | 1083 | |
| ABL1 | Abl | TK | 2hz0 | B | A | 2-{[(6-oxo-1,6-dihydropyridin-3-yl)methyl]amino}-n-[4-propyl-3-(trifluoromethyl)phenyl]benzamide | Human | 1095 | |
| ABL1 | Abl | TK | 2hz0 | B | B | 2-{[(6-oxo-1,6-dihydropyridin-3-yl)methyl]amino}-n-[4-propyl-3-(trifluoromethyl)phenyl]benzamide | Human | 1109 | |
| ABL1 | Abl | TK | 2hz4 | A | | - | Human | 1059 | |
| ABL1 | Abl | TK | 2hz4 | B | | 1,2,3,4-tetrahydrogen-staurosporine | Human | 1058 | |
| ABL1 | Abl | TK | 2hz4 | C | | - | Human | 1067 | |
| ABL1 | Abl | TK | 2hzi | A | A | 6-(2,6-dichlorophenyl)-2-[(4-fluoro-3-methylphenyl)amino]-8-methylpyrido[2,3-d]pyrimidin-7(8h)-one | Human | 1102 | |
| ABL1 | Abl | TK | 2hzi | A | B | 6-(2,6-dichlorophenyl)-2-[(4-fluoro-3-methylphenyl)amino]-8-methylpyrido[2,3-d]pyrimidin-7(8h)-one | Human | 1087 | |
| ABL1 | Abl | TK | 2hzi | B | A | 6-(2,6-dichlorophenyl)-2-[(4-fluoro-3-methylphenyl)amino]-8-methylpyrido[2,3-d]pyrimidin-7(8h)-one | Human | 1108 | |
| ABL1 | Abl | TK | 2hzi | B | B | 6-(2,6-dichlorophenyl)-2-[(4-fluoro-3-methylphenyl)amino]-8-methylpyrido[2,3-d]pyrimidin-7(8h)-one | Human | 1055 | |
| ABL1 | Abl | TK | 2v7a | A | | n-[(3e)-5-[(2r)-2-methoxy-2-phenylacetyl]pyrrolo[3,4-c]pyrazol-3(5h)-ylidene]-4-(4-methylpiperazin-1-yl)benzamide | Human | 1088 | |
| ABL1 | Abl | TK | 2v7a | B | | n-[(3e)-5-[(2r)-2-methoxy-2-phenylacetyl]pyrrolo[3,4-c]pyrazol-3(5h)-ylidene]-4-(4-methylpiperazin-1-yl)benzamide | Human | 1072 | |
| ABL1 | Abl | TK | 3cs9 | A | A | nilotinib | Human | 1080 | |
| ABL1 | Abl | TK | 3cs9 | A | B | nilotinib | Human | 1107 | |
| ABL1 | Abl | TK | 3cs9 | B | A | nilotinib | Human | 1050 | |
| ABL1 | Abl | TK | 3cs9 | B | B | nilotinib | Human | 1112 | |
| ABL1 | Abl | TK | 3cs9 | C | A | nilotinib | Human | 1046 | |
| ABL1 | Abl | TK | 3cs9 | C | B | nilotinib | Human | 1093 | |
| ABL1 | Abl | TK | 3cs9 | D | A | nilotinib | Human | 1077 | |
| ABL1 | Abl | TK | 3cs9 | D | B | nilotinib | Human | 1066 | |
| ABL1 | Abl | TK | 3pyy | A | A | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Human | 1049 | |
| ABL1 | Abl | TK | 3pyy | A | B | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Human | 1071 | |
| ABL1 | Abl | TK | 3pyy | B | A | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Human | 1062 | |
| ABL1 | Abl | TK | 3pyy | B | B | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Human | 1098 | |
| ABL1 | Abl | TK | 3qri | A | A | 4-[4-({[3-tert-butyl-1-(quinolin-6-yl)-1h-pyrazol-5-yl]carbamoyl}amino)-3-fluorophenoxy]-n-methylpyridine-2-carboxamide | Human | 1051 | |
| ABL1 | Abl | TK | 3qri | A | B | 4-[4-({[3-tert-butyl-1-(quinolin-6-yl)-1h-pyrazol-5-yl]carbamoyl}amino)-3-fluorophenoxy]-n-methylpyridine-2-carboxamide | Human | 1047 | |
| ABL1 | Abl | TK | 3qri | B | A | 4-[4-({[3-tert-butyl-1-(quinolin-6-yl)-1h-pyrazol-5-yl]carbamoyl}amino)-3-fluorophenoxy]-n-methylpyridine-2-carboxamide | Human | 1103 | |
| ABL1 | Abl | TK | 3qri | B | B | 4-[4-({[3-tert-butyl-1-(quinolin-6-yl)-1h-pyrazol-5-yl]carbamoyl}amino)-3-fluorophenoxy]-n-methylpyridine-2-carboxamide | Human | 1076 | |
| ABL1 | Abl | TK | 3qrj | A | A | 4-[4-({[3-tert-butyl-1-(quinolin-6-yl)-1h-pyrazol-5-yl]carbamoyl}amino)-3-fluorophenoxy]-n-methylpyridine-2-carboxamide | Human | 1085 | |
| ABL1 | Abl | TK | 3qrj | A | B | 4-[4-({[3-tert-butyl-1-(quinolin-6-yl)-1h-pyrazol-5-yl]carbamoyl}amino)-3-fluorophenoxy]-n-methylpyridine-2-carboxamide | Human | 1099 | |
| ABL1 | Abl | TK | 3qrj | B | A | 4-[4-({[3-tert-butyl-1-(quinolin-6-yl)-1h-pyrazol-5-yl]carbamoyl}amino)-3-fluorophenoxy]-n-methylpyridine-2-carboxamide | Human | 1101 | |
| ABL1 | Abl | TK | 3qrj | B | B | 4-[4-({[3-tert-butyl-1-(quinolin-6-yl)-1h-pyrazol-5-yl]carbamoyl}amino)-3-fluorophenoxy]-n-methylpyridine-2-carboxamide | Human | 1070 | |
| ABL1 | Abl | TK | 3qrk | A | | (3s)-6-(3-tert-butyl-5-{[(2,3-dichlorophenyl)carbamoyl]amino}-1h-pyrazol-1-yl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid | Human | 1056 | |
| ABL1 | Abl | TK | 3ue4 | A | | 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile | Human | 1057 | |
| ABL1 | Abl | TK | 3ue4 | B | | 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile | Human | 1074 | |
| ABL1 | Abl | TK | 4twp | A | | axitinib | Human | 1091 | |
| ABL1 | Abl | TK | 4twp | B | | axitinib | Human | 1081 | |
| ABL1 | Abl | TK | 4wa9 | A | | axitinib | Human | 1061 | |
| ABL1 | Abl | TK | 4wa9 | B | | axitinib | Human | 1063 | |
| ABL1 | Abl | TK | 4xey | A | | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 1094 | |
| ABL1 | Abl | TK | 4xey | B | | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 1100 | |
| ABL1 | Abl | TK | 4yc8 | A | | 2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-n-(4-phenoxyphenyl)-1,3-thiazole-5-carboxamide | Human | 6419 | |
| ABL1 | Abl | TK | 4yc8 | B | | 2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-n-(4-phenoxyphenyl)-1,3-thiazole-5-carboxamide | Human | 6420 | |
| ABL1 | Abl | TK | 4zog | A | | cyclopropanecarboxylic acid {4-[4-(4-methyl-piperazin-1-yl)-6-(5-methyl-2h-pyrazol-3-ylamino)-pyrimidin-2-ylsulfanyl]-phenyl}-amide | Human | 7043 | |
| ABL1 | Abl | TK | 4zog | B | | cyclopropanecarboxylic acid {4-[4-(4-methyl-piperazin-1-yl)-6-(5-methyl-2h-pyrazol-3-ylamino)-pyrimidin-2-ylsulfanyl]-phenyl}-amide | Human | 7042 | |
| ABL1 | Abl | TK | 5hu9 | A | A | 4-[(4-methylpiperazin-1-yl)methyl]-n-(4-methyl-3-{[1-(pyridin-3-ylcarbonyl)piperidin-4-yl]oxy}phenyl)-3-(trifluoromethyl)benzamide | Human | 6754 | |
| ABL1 | Abl | TK | 5hu9 | A | B | 4-[(4-methylpiperazin-1-yl)methyl]-n-(4-methyl-3-{[1-(pyridin-3-ylcarbonyl)piperidin-4-yl]oxy}phenyl)-3-(trifluoromethyl)benzamide | Human | 6755 | |
| ABL1 | Abl | TK | 5mo4 | A | A | nilotinib | Human | 7527 | |
| ABL1 | Abl | TK | 5mo4 | A | B | nilotinib | Human | 7526 | |
| ABL1 | Abl | TK | 6bl8 | A | A | purvalanol b | Human | 9699 | |
| ABL1 | Abl | TK | 6bl8 | A | B | purvalanol b | Human | 9698 | |
| ABL1 | Abl | TK | 6bl8 | B | A | purvalanol b | Human | 9701 | |
| ABL1 | Abl | TK | 6bl8 | B | B | purvalanol b | Human | 9700 | |
| ABL1 | Abl | TK | 6npe | A | A | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Human | 10946 | |
| ABL1 | Abl | TK | 6npe | A | B | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Human | 10943 | |
| ABL1 | Abl | TK | 6npe | B | A | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Human | 10947 | |
| ABL1 | Abl | TK | 6npe | B | B | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Human | 10945 | |
| ABL1 | Abl | TK | 6npu | A | | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Human | 10942 | |
| ABL1 | Abl | TK | 6npu | B | | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Human | 10944 | |
| ABL1 | Abl | TK | 6npv | A | A | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Human | 10948 | |
| ABL1 | Abl | TK | 6npv | A | B | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Human | 10951 | |
| ABL1 | Abl | TK | 6npv | B | A | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Human | 10949 | |
| ABL1 | Abl | TK | 6npv | B | B | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Human | 10950 | |
| ABL1 | Abl | TK | 6xr6 | A | 1 | - | Human | 12905 | |
| ABL1 | Abl | TK | 6xr6 | A | 10 | - | Human | 12901 | |
| ABL1 | Abl | TK | 6xr6 | A | 11 | - | Human | 12872 | |
| ABL1 | Abl | TK | 6xr6 | A | 12 | - | Human | 12871 | |
| ABL1 | Abl | TK | 6xr6 | A | 13 | - | Human | 12869 | |
| ABL1 | Abl | TK | 6xr6 | A | 14 | - | Human | 12873 | |
| ABL1 | Abl | TK | 6xr6 | A | 15 | - | Human | 12862 | |
| ABL1 | Abl | TK | 6xr6 | A | 16 | - | Human | 12902 | |
| ABL1 | Abl | TK | 6xr6 | A | 17 | - | Human | 12874 | |
| ABL1 | Abl | TK | 6xr6 | A | 18 | - | Human | 12912 | |
| ABL1 | Abl | TK | 6xr6 | A | 19 | - | Human | 12892 | |
| ABL1 | Abl | TK | 6xr6 | A | 2 | - | Human | 12878 | |
| ABL1 | Abl | TK | 6xr6 | A | 20 | - | Human | 12861 | |
| ABL1 | Abl | TK | 6xr6 | A | 3 | - | Human | 12908 | |
| ABL1 | Abl | TK | 6xr6 | A | 4 | - | Human | 12898 | |
| ABL1 | Abl | TK | 6xr6 | A | 5 | - | Human | 12858 | |
| ABL1 | Abl | TK | 6xr6 | A | 6 | - | Human | 12896 | |
| ABL1 | Abl | TK | 6xr6 | A | 7 | - | Human | 12881 | |
| ABL1 | Abl | TK | 6xr6 | A | 8 | - | Human | 12906 | |
| ABL1 | Abl | TK | 6xr6 | A | 9 | - | Human | 12885 | |
| ABL1 | Abl | TK | 6xr7 | A | 1 | - | Human | 12867 | |
| ABL1 | Abl | TK | 6xr7 | A | 10 | - | Human | 12903 | |
| ABL1 | Abl | TK | 6xr7 | A | 11 | - | Human | 12866 | |
| ABL1 | Abl | TK | 6xr7 | A | 12 | - | Human | 12860 | |
| ABL1 | Abl | TK | 6xr7 | A | 13 | - | Human | 12910 | |
| ABL1 | Abl | TK | 6xr7 | A | 14 | - | Human | 12865 | |
| ABL1 | Abl | TK | 6xr7 | A | 15 | - | Human | 12913 | |
| ABL1 | Abl | TK | 6xr7 | A | 16 | - | Human | 12859 | |
| ABL1 | Abl | TK | 6xr7 | A | 17 | - | Human | 12870 | |
| ABL1 | Abl | TK | 6xr7 | A | 18 | - | Human | 12909 | |
| ABL1 | Abl | TK | 6xr7 | A | 19 | - | Human | 12879 | |
| ABL1 | Abl | TK | 6xr7 | A | 2 | - | Human | 12883 | |
| ABL1 | Abl | TK | 6xr7 | A | 20 | - | Human | 12914 | |
| ABL1 | Abl | TK | 6xr7 | A | 3 | - | Human | 12900 | |
| ABL1 | Abl | TK | 6xr7 | A | 4 | - | Human | 12894 | |
| ABL1 | Abl | TK | 6xr7 | A | 5 | - | Human | 12857 | |
| ABL1 | Abl | TK | 6xr7 | A | 6 | - | Human | 12897 | |
| ABL1 | Abl | TK | 6xr7 | A | 7 | - | Human | 12907 | |
| ABL1 | Abl | TK | 6xr7 | A | 8 | - | Human | 12863 | |
| ABL1 | Abl | TK | 6xr7 | A | 9 | - | Human | 12915 | |
| ABL1 | Abl | TK | 6xrg | A | 1 | - | Human | 12890 | |
| ABL1 | Abl | TK | 6xrg | A | 10 | - | Human | 12889 | |
| ABL1 | Abl | TK | 6xrg | A | 11 | - | Human | 12877 | |
| ABL1 | Abl | TK | 6xrg | A | 12 | - | Human | 12882 | |
| ABL1 | Abl | TK | 6xrg | A | 13 | - | Human | 12904 | |
| ABL1 | Abl | TK | 6xrg | A | 14 | - | Human | 12875 | |
| ABL1 | Abl | TK | 6xrg | A | 15 | - | Human | 12911 | |
| ABL1 | Abl | TK | 6xrg | A | 16 | - | Human | 12887 | |
| ABL1 | Abl | TK | 6xrg | A | 17 | - | Human | 12916 | |
| ABL1 | Abl | TK | 6xrg | A | 18 | - | Human | 12880 | |
| ABL1 | Abl | TK | 6xrg | A | 19 | - | Human | 12886 | |
| ABL1 | Abl | TK | 6xrg | A | 2 | - | Human | 12895 | |
| ABL1 | Abl | TK | 6xrg | A | 20 | - | Human | 12888 | |
| ABL1 | Abl | TK | 6xrg | A | 3 | - | Human | 12893 | |
| ABL1 | Abl | TK | 6xrg | A | 4 | - | Human | 12899 | |
| ABL1 | Abl | TK | 6xrg | A | 5 | - | Human | 12884 | |
| ABL1 | Abl | TK | 6xrg | A | 6 | - | Human | 12876 | |
| ABL1 | Abl | TK | 6xrg | A | 7 | - | Human | 12868 | |
| ABL1 | Abl | TK | 6xrg | A | 8 | - | Human | 12864 | |
| ABL1 | Abl | TK | 6xrg | A | 9 | - | Human | 12891 | |
| ABL1 | Abl | TK | 7cc2 | A | | [4-[5-[5-(dimethylcarbamoyl)pyridin-3-yl]-1h-pyrrolo[2,3-b]pyridin-3-yl]-2-methyl-phenyl]boronic acid | Human | 13620 | |
| ABL1 | Abl | TK | 7dt2 | A | | [4-[5-[5-(dimethylcarbamoyl)pyridin-3-yl]-1h-pyrrolo[2,3-b]pyridin-3-yl]-2-methanoyl-5-methoxy-phenyl]boronic acid | Human | 13621 | |
| ABL1 | Abl | TK | 7n9g | A | | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 14197 | |
| ABL1 | Abl | TK | 7w7x | A | | 5-[5-(dimethylcarbamoyl)pyridin-3-yl]-3-(5-fluorosulfonyloxy-2-methoxy-phenyl)-1h-pyrrolo[2,3-b]pyridine | Human | 14196 | |
| ABL1 | Abl | TK | 7w7y | A | | 5-[3-(5-methanoyl-2-methoxy-4-oxidanyl-phenyl)-1~{h}-pyrrolo[2,3-b]pyridin-5-yl]-~{n},~{n}-dimethyl-pyridine-3-carboxamide | Human | 14195 | |
| ABL1 | Abl | TK | 8h7f | A | | 1-[6-(6-methoxyisoquinolin-7-yl)-1,3-benzothiazol-2-yl]-3-(2-oxidanylideneethyl)urea | Human | 14632 | |
| ABL1 | Abl | TK | 8h7h | A | | 5-[3-(6-methoxyisoquinolin-7-yl)-1~{h}-pyrrolo[2,3-b]pyridin-5-yl]-~{n}-methyl-~{n}-prop-2-ynyl-pyridine-3-carboxamide | Human | 14666 | |
| ABL1 | Abl | TK | 8ssn | A | | 6,7-dimethoxy-n-(4-phenoxyphenyl)quinazolin-4-amine | Human | 14878 | |
| Abl2 (ABL2) | Abl | TK | 4xli | A | | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Mouse | 5689 | |
| Abl2 (ABL2) | Abl | TK | 4xli | B | | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Mouse | 5690 | |
| ABL2 | Abl | TK | 2xyn | A | A | cyclopropanecarboxylic acid {4-[4-(4-methyl-piperazin-1-yl)-6-(5-methyl-2h-pyrazol-3-ylamino)-pyrimidin-2-ylsulfanyl]-phenyl}-amide | Human | 110 | |
| ABL2 | Abl | TK | 2xyn | A | B | cyclopropanecarboxylic acid {4-[4-(4-methyl-piperazin-1-yl)-6-(5-methyl-2h-pyrazol-3-ylamino)-pyrimidin-2-ylsulfanyl]-phenyl}-amide | Human | 112 | |
| ABL2 | Abl | TK | 2xyn | B | A | cyclopropanecarboxylic acid {4-[4-(4-methyl-piperazin-1-yl)-6-(5-methyl-2h-pyrazol-3-ylamino)-pyrimidin-2-ylsulfanyl]-phenyl}-amide | Human | 111 | |
| ABL2 | Abl | TK | 2xyn | B | B | cyclopropanecarboxylic acid {4-[4-(4-methyl-piperazin-1-yl)-6-(5-methyl-2h-pyrazol-3-ylamino)-pyrimidin-2-ylsulfanyl]-phenyl}-amide | Human | 113 | |
| ABL2 | Abl | TK | 2xyn | C | A | cyclopropanecarboxylic acid {4-[4-(4-methyl-piperazin-1-yl)-6-(5-methyl-2h-pyrazol-3-ylamino)-pyrimidin-2-ylsulfanyl]-phenyl}-amide | Human | 116 | |
| ABL2 | Abl | TK | 2xyn | C | B | cyclopropanecarboxylic acid {4-[4-(4-methyl-piperazin-1-yl)-6-(5-methyl-2h-pyrazol-3-ylamino)-pyrimidin-2-ylsulfanyl]-phenyl}-amide | Human | 114 | |
| ABL2 | Abl | TK | 3gvu | A | A | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Human | 117 | |
| ABL2 | Abl | TK | 3gvu | A | B | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Human | 109 | |
| ABL2 | Abl | TK | 3hmi | A | A | 5-amino-3-{[4-(aminosulfonyl)phenyl]amino}-n-(2,6-difluorophenyl)-1h-1,2,4-triazole-1-carbothioamide | Human | 115 | |
| ABL2 | Abl | TK | 3hmi | A | B | 5-amino-3-{[4-(aminosulfonyl)phenyl]amino}-n-(2,6-difluorophenyl)-1h-1,2,4-triazole-1-carbothioamide | Human | 118 | |
| ACVR1 (ALK2) | STKR | TKL | 3h9r | A | | 6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine | Human | 1531 | |
| ACVR1 (ALK2) | STKR | TKL | 3mtf | A | A | 3-[6-amino-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenol | Human | 1513 | |
| ACVR1 (ALK2) | STKR | TKL | 3mtf | A | B | 3-[6-amino-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenol | Human | 1521 | |
| ACVR1 (ALK2) | STKR | TKL | 3mtf | B | A | 3-[6-amino-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenol | Human | 1515 | |
| ACVR1 (ALK2) | STKR | TKL | 3mtf | B | B | 3-[6-amino-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenol | Human | 1530 | |
| ACVR1 (ALK2) | STKR | TKL | 3oom | A | A | 1-{3-[6-(tetrahydro-2h-pyran-4-ylamino)imidazo[1,2-b]pyridazin-3-yl]phenyl}ethanone | Human | 1517 | |
| ACVR1 (ALK2) | STKR | TKL | 3oom | A | B | 1-{3-[6-(tetrahydro-2h-pyran-4-ylamino)imidazo[1,2-b]pyridazin-3-yl]phenyl}ethanone | Human | 1518 | |
| ACVR1 (ALK2) | STKR | TKL | 3q4u | A | A | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | 1527 | |
| ACVR1 (ALK2) | STKR | TKL | 3q4u | A | B | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | 1524 | |
| ACVR1 (ALK2) | STKR | TKL | 3q4u | B | A | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | 1510 | |
| ACVR1 (ALK2) | STKR | TKL | 3q4u | B | B | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | 1523 | |
| ACVR1 (ALK2) | STKR | TKL | 3q4u | C | A | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | 1516 | |
| ACVR1 (ALK2) | STKR | TKL | 3q4u | C | B | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | 1533 | |
| ACVR1 (ALK2) | STKR | TKL | 3q4u | D | A | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | 1520 | |
| ACVR1 (ALK2) | STKR | TKL | 3q4u | D | B | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | 1529 | |
| ACVR1 (ALK2) | STKR | TKL | 4bgg | A | A | 1-{4-[5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenyl}piperazine | Human | 1528 | |
| ACVR1 (ALK2) | STKR | TKL | 4bgg | A | B | 1-{4-[5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenyl}piperazine | Human | 1508 | |
| ACVR1 (ALK2) | STKR | TKL | 4bgg | B | A | 1-{4-[5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenyl}piperazine | Human | 1514 | |
| ACVR1 (ALK2) | STKR | TKL | 4bgg | B | B | 1-{4-[5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenyl}piperazine | Human | 1526 | |
| ACVR1 (ALK2) | STKR | TKL | 4bgg | C | A | 1-{4-[5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenyl}piperazine | Human | 1511 | |
| ACVR1 (ALK2) | STKR | TKL | 4bgg | C | B | 1-{4-[5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenyl}piperazine | Human | 1522 | |
| ACVR1 (ALK2) | STKR | TKL | 4bgg | D | A | 1-{4-[5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenyl}piperazine | Human | 1519 | |
| ACVR1 (ALK2) | STKR | TKL | 4bgg | D | B | 1-{4-[5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenyl}piperazine | Human | 1512 | |
| ACVR1 (ALK2) | STKR | TKL | 4c02 | A | A | 6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine | Human | 1525 | |
| ACVR1 (ALK2) | STKR | TKL | 4c02 | A | B | 6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine | Human | 1532 | |
| ACVR1 (ALK2) | STKR | TKL | 4dym | A | | 1-(3-{6-[(cyclopropylmethyl)amino]imidazo[1,2-b]pyridazin-3-yl}phenyl)ethanone | Human | 1509 | |
| ACVR1 (ALK2) | STKR | TKL | 5oxg | A | A | 5-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | 8514 | |
| ACVR1 (ALK2) | STKR | TKL | 5oxg | A | B | 5-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | 8518 | |
| ACVR1 (ALK2) | STKR | TKL | 5oxg | B | A | 5-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | 8516 | |
| ACVR1 (ALK2) | STKR | TKL | 5oxg | B | B | 5-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | 8519 | |
| ACVR1 (ALK2) | STKR | TKL | 5oxg | C | A | 5-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | 8517 | |
| ACVR1 (ALK2) | STKR | TKL | 5oxg | C | B | 5-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | 8513 | |
| ACVR1 (ALK2) | STKR | TKL | 5oxg | D | A | 5-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | 8520 | |
| ACVR1 (ALK2) | STKR | TKL | 5oxg | D | B | 5-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | 8515 | |
| ACVR1 (ALK2) | STKR | TKL | 5oy6 | A | | cyclical inhibitor od36 | Human | 8532 | |
| ACVR1 (ALK2) | STKR | TKL | 5oy6 | B | | cyclical inhibitor od36 | Human | 8531 | |
| ACVR1 (ALK2) | STKR | TKL | 5oy6 | C | | cyclical inhibitor od36 | Human | 8529 | |
| ACVR1 (ALK2) | STKR | TKL | 5oy6 | D | | cyclical inhibitor od36 | Human | 8534 | |
| ACVR1 (ALK2) | STKR | TKL | 5s75 | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13714 | |
| ACVR1 (ALK2) | STKR | TKL | 5s75 | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13718 | |
| ACVR1 (ALK2) | STKR | TKL | 5s76 | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13691 | |
| ACVR1 (ALK2) | STKR | TKL | 5s76 | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13672 | |
| ACVR1 (ALK2) | STKR | TKL | 5s77 | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13694 | |
| ACVR1 (ALK2) | STKR | TKL | 5s77 | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13698 | |
| ACVR1 (ALK2) | STKR | TKL | 5s78 | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13716 | |
| ACVR1 (ALK2) | STKR | TKL | 5s78 | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13686 | |
| ACVR1 (ALK2) | STKR | TKL | 5s79 | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13704 | |
| ACVR1 (ALK2) | STKR | TKL | 5s79 | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13708 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7a | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13683 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7a | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13644 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7b | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13650 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7b | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13719 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7c | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13689 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7c | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13690 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7c | A | C | - | Human | 13702 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7c | A | D | - | Human | 13680 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7d | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13730 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7d | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13668 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7e | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13715 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7e | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13643 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7f | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13671 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7f | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13737 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7g | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13713 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7g | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13717 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7h | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13682 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7h | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13660 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7i | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13699 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7i | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13663 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7i | A | C | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13653 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7j | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13712 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7j | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13648 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7k | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13649 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7k | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13732 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7l | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13676 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7l | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13736 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7l | A | C | - | Human | 13665 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7m | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13666 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7m | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13739 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7m | A | C | - | Human | 13705 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7n | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13655 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7n | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13659 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7o | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13733 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7o | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13664 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7o | A | C | - | Human | 13647 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7p | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13695 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7p | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13687 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7q | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13670 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7q | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13678 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7r | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13731 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7r | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13654 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7s | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13667 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7s | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13677 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7s | A | C | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13651 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7t | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13723 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7t | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13709 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7u | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13675 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7u | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13696 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7v | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13707 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7v | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13711 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7w | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13700 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7w | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13662 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7x | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13646 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7x | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13692 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7y | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13727 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7y | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13684 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7z | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13652 | |
| ACVR1 (ALK2) | STKR | TKL | 5s7z | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13674 | |
| ACVR1 (ALK2) | STKR | TKL | 5s80 | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13728 | |
| ACVR1 (ALK2) | STKR | TKL | 5s80 | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13669 | |
| ACVR1 (ALK2) | STKR | TKL | 5s81 | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13661 | |
| ACVR1 (ALK2) | STKR | TKL | 5s81 | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13697 | |
| ACVR1 (ALK2) | STKR | TKL | 5s82 | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13681 | |
| ACVR1 (ALK2) | STKR | TKL | 5s82 | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13701 | |
| ACVR1 (ALK2) | STKR | TKL | 5s83 | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13706 | |
| ACVR1 (ALK2) | STKR | TKL | 5s83 | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13685 | |
| ACVR1 (ALK2) | STKR | TKL | 5s84 | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13734 | |
| ACVR1 (ALK2) | STKR | TKL | 5s84 | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13656 | |
| ACVR1 (ALK2) | STKR | TKL | 5s84 | A | C | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13722 | |
| ACVR1 (ALK2) | STKR | TKL | 5s85 | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13710 | |
| ACVR1 (ALK2) | STKR | TKL | 5s85 | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13720 | |
| ACVR1 (ALK2) | STKR | TKL | 5s85 | A | C | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13679 | |
| ACVR1 (ALK2) | STKR | TKL | 5s86 | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13724 | |
| ACVR1 (ALK2) | STKR | TKL | 5s86 | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13729 | |
| ACVR1 (ALK2) | STKR | TKL | 5s87 | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13738 | |
| ACVR1 (ALK2) | STKR | TKL | 5s87 | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13735 | |
| ACVR1 (ALK2) | STKR | TKL | 5s88 | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13657 | |
| ACVR1 (ALK2) | STKR | TKL | 5s88 | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13703 | |
| ACVR1 (ALK2) | STKR | TKL | 5s89 | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13673 | |
| ACVR1 (ALK2) | STKR | TKL | 5s89 | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13688 | |
| ACVR1 (ALK2) | STKR | TKL | 5s8a | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13725 | |
| ACVR1 (ALK2) | STKR | TKL | 5s8a | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13693 | |
| ACVR1 (ALK2) | STKR | TKL | 5s8b | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13726 | |
| ACVR1 (ALK2) | STKR | TKL | 5s8b | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13721 | |
| ACVR1 (ALK2) | STKR | TKL | 5s9k | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13645 | |
| ACVR1 (ALK2) | STKR | TKL | 5s9k | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 13658 | |
| ACVR1 (ALK2) | STKR | TKL | 6acr | A | | n-(4-methoxyphenyl)-4-[3-(pyridin-3-yl)-1h-pyrazol-4-yl]pyrimidin-2-amine | Human | 10969 | |
| ACVR1 (ALK2) | STKR | TKL | 6acr | B | | n-(4-methoxyphenyl)-4-[3-(pyridin-3-yl)-1h-pyrazol-4-yl]pyrimidin-2-amine | Human | 10968 | |
| ACVR1 (ALK2) | STKR | TKL | 6eix | A | A | 3-[6-amino-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenol | Human | 8530 | |
| ACVR1 (ALK2) | STKR | TKL | 6eix | A | B | 3-[6-amino-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenol | Human | 8533 | |
| ACVR1 (ALK2) | STKR | TKL | 6gi6 | A | | 5-methyl-6-quinolin-5-yl-3~{h}-quinazolin-4-one | Human | 9919 | |
| ACVR1 (ALK2) | STKR | TKL | 6gin | A | A | 3-(4-morpholin-4-ylphenyl)-6-quinolin-4-yl-quinazolin-4-one | Human | 9914 | |
| ACVR1 (ALK2) | STKR | TKL | 6gin | A | B | 3-(4-morpholin-4-ylphenyl)-6-quinolin-4-yl-quinazolin-4-one | Human | 9918 | |
| ACVR1 (ALK2) | STKR | TKL | 6gin | B | A | 3-(4-morpholin-4-ylphenyl)-6-quinolin-4-yl-quinazolin-4-one | Human | 9920 | |
| ACVR1 (ALK2) | STKR | TKL | 6gin | B | B | 3-(4-morpholin-4-ylphenyl)-6-quinolin-4-yl-quinazolin-4-one | Human | 9916 | |
| ACVR1 (ALK2) | STKR | TKL | 6gip | A | A | 2,5-dimethyl-6-quinolin-4-yl-3~{h}-quinazolin-4-one | Human | 9915 | |
| ACVR1 (ALK2) | STKR | TKL | 6gip | A | B | 2,5-dimethyl-6-quinolin-4-yl-3~{h}-quinazolin-4-one | Human | 9917 | |
| ACVR1 (ALK2) | STKR | TKL | 6i1s | A | A | (4~{s},5~{r},6~{z},9~{s},10~{s},12~{e})-16-(ethylamino)-4,5-dimethyl-9,10,18-tris(oxidanyl)-3-oxabicyclo[12.4.0]octadeca-1(14),6,12,15,17-pentaene-2,8-dione | Human | 11603 | |
| ACVR1 (ALK2) | STKR | TKL | 6i1s | A | B | (4~{s},5~{r},6~{z},9~{s},10~{s},12~{e})-16-(ethylamino)-4,5-dimethyl-9,10,18-tris(oxidanyl)-3-oxabicyclo[12.4.0]octadeca-1(14),6,12,15,17-pentaene-2,8-dione | Human | 11604 | |
| ACVR1 (ALK2) | STKR | TKL | 6jux | A | A | 4-(1-ethyl-3-pyridin-3-yl-pyrazol-4-yl)-~{n}-(4-piperazin-1-ylphenyl)pyrimidin-2-amine | Human | 12161 | |
| ACVR1 (ALK2) | STKR | TKL | 6jux | A | B | 4-(1-ethyl-3-pyridin-3-yl-pyrazol-4-yl)-~{n}-(4-piperazin-1-ylphenyl)pyrimidin-2-amine | Human | 12160 | |
| ACVR1 (ALK2) | STKR | TKL | 6srh | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 11632 | |
| ACVR1 (ALK2) | STKR | TKL | 6srh | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 11630 | |
| ACVR1 (ALK2) | STKR | TKL | 6srh | B | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 11631 | |
| ACVR1 (ALK2) | STKR | TKL | 6srh | B | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 11633 | |
| ACVR1 (ALK2) | STKR | TKL | 6szm | A | A | 1-[4-[4-methyl-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenyl]piperazine | Human | 11735 | |
| ACVR1 (ALK2) | STKR | TKL | 6szm | A | B | 1-[4-[4-methyl-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenyl]piperazine | Human | 11737 | |
| ACVR1 (ALK2) | STKR | TKL | 6szm | B | A | 1-[4-[4-methyl-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenyl]piperazine | Human | 11734 | |
| ACVR1 (ALK2) | STKR | TKL | 6szm | B | B | 1-[4-[4-methyl-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenyl]piperazine | Human | 11736 | |
| ACVR1 (ALK2) | STKR | TKL | 6t6d | A | A | 2-methoxy-4-[4-methyl-5-(4-piperazin-1-ylphenyl)pyridin-3-yl]benzamide | Human | 11779 | |
| ACVR1 (ALK2) | STKR | TKL | 6t6d | A | B | 2-methoxy-4-[4-methyl-5-(4-piperazin-1-ylphenyl)pyridin-3-yl]benzamide | Human | 11784 | |
| ACVR1 (ALK2) | STKR | TKL | 6t6d | B | A | 2-methoxy-4-[4-methyl-5-(4-piperazin-1-ylphenyl)pyridin-3-yl]benzamide | Human | 11781 | |
| ACVR1 (ALK2) | STKR | TKL | 6t6d | B | B | 2-methoxy-4-[4-methyl-5-(4-piperazin-1-ylphenyl)pyridin-3-yl]benzamide | Human | 11782 | |
| ACVR1 (ALK2) | STKR | TKL | 6t6d | C | A | 2-methoxy-4-[4-methyl-5-(4-piperazin-1-ylphenyl)pyridin-3-yl]benzamide | Human | 11778 | |
| ACVR1 (ALK2) | STKR | TKL | 6t6d | C | B | 2-methoxy-4-[4-methyl-5-(4-piperazin-1-ylphenyl)pyridin-3-yl]benzamide | Human | 11780 | |
| ACVR1 (ALK2) | STKR | TKL | 6t6d | D | A | 2-methoxy-4-[4-methyl-5-(4-piperazin-1-ylphenyl)pyridin-3-yl]benzamide | Human | 11783 | |
| ACVR1 (ALK2) | STKR | TKL | 6t6d | D | B | 2-methoxy-4-[4-methyl-5-(4-piperazin-1-ylphenyl)pyridin-3-yl]benzamide | Human | 11785 | |
| ACVR1 (ALK2) | STKR | TKL | 6t8n | A | A | cyclopropyl-[4-[6-[5-(4-ethoxy-1-propan-2-yl-piperidin-4-yl)pyridin-2-yl]pyrrolo[1,2-b]pyridazin-4-yl]piperazin-1-yl]methanone | Human | 11831 | |
| ACVR1 (ALK2) | STKR | TKL | 6t8n | A | B | cyclopropyl-[4-[6-[5-(4-ethoxy-1-propan-2-yl-piperidin-4-yl)pyridin-2-yl]pyrrolo[1,2-b]pyridazin-4-yl]piperazin-1-yl]methanone | Human | 11830 | |
| ACVR1 (ALK2) | STKR | TKL | 6t8n | B | A | cyclopropyl-[4-[6-[5-(4-ethoxy-1-propan-2-yl-piperidin-4-yl)pyridin-2-yl]pyrrolo[1,2-b]pyridazin-4-yl]piperazin-1-yl]methanone | Human | 11828 | |
| ACVR1 (ALK2) | STKR | TKL | 6t8n | B | B | cyclopropyl-[4-[6-[5-(4-ethoxy-1-propan-2-yl-piperidin-4-yl)pyridin-2-yl]pyrrolo[1,2-b]pyridazin-4-yl]piperazin-1-yl]methanone | Human | 11829 | |
| ACVR1 (ALK2) | STKR | TKL | 6tn8 | A | A | 4-[4-[(dimethylamino)methyl]-2,5-dimethoxy-phenyl]-2-methyl-2,7-naphthyridin-1-one | Human | 11888 | |
| ACVR1 (ALK2) | STKR | TKL | 6tn8 | A | B | 4-[4-[(dimethylamino)methyl]-2,5-dimethoxy-phenyl]-2-methyl-2,7-naphthyridin-1-one | Human | 11887 | |
| ACVR1 (ALK2) | STKR | TKL | 6unq | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 13783 | |
| ACVR1 (ALK2) | STKR | TKL | 6unq | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 13784 | |
| ACVR1 (ALK2) | STKR | TKL | 6unr | A | | phosphoaminophosphonic acid-adenylate ester | Human | 13785 | |
| ACVR1 (ALK2) | STKR | TKL | 6uns | A | A | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | 13782 | |
| ACVR1 (ALK2) | STKR | TKL | 6uns | A | B | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | 13781 | |
| ACVR1 (ALK2) | STKR | TKL | 6z36 | A | A | 4-methyl-3-(4-piperidin-4-ylphenyl)-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 12277 | |
| ACVR1 (ALK2) | STKR | TKL | 6z36 | A | B | 4-methyl-3-(4-piperidin-4-ylphenyl)-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 12278 | |
| ACVR1 (ALK2) | STKR | TKL | 6z36 | B | A | 4-methyl-3-(4-piperidin-4-ylphenyl)-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 12276 | |
| ACVR1 (ALK2) | STKR | TKL | 6z36 | B | B | 4-methyl-3-(4-piperidin-4-ylphenyl)-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 12275 | |
| ACVR1 (ALK2) | STKR | TKL | 6zgc | A | | n-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5-(tetrahydro-2h-pyran-4-yloxy)quinazolin-4-amine | Human | 12638 | |
| ACVR1 (ALK2) | STKR | TKL | 6zgc | B | | n-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5-(tetrahydro-2h-pyran-4-yloxy)quinazolin-4-amine | Human | 12641 | |
| ACVR1 (ALK2) | STKR | TKL | 6zgc | C | | n-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5-(tetrahydro-2h-pyran-4-yloxy)quinazolin-4-amine | Human | 12640 | |
| ACVR1 (ALK2) | STKR | TKL | 6zgc | D | | n-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5-(tetrahydro-2h-pyran-4-yloxy)quinazolin-4-amine | Human | 12639 | |
| ACVR1 (ALK2) | STKR | TKL | 7a21 | A | A | 4-methyl-3-[4-(pyrrolidin-1-ylmethyl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 12777 | |
| ACVR1 (ALK2) | STKR | TKL | 7a21 | A | B | 4-methyl-3-[4-(pyrrolidin-1-ylmethyl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 12779 | |
| ACVR1 (ALK2) | STKR | TKL | 7a21 | B | A | 4-methyl-3-[4-(pyrrolidin-1-ylmethyl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 12776 | |
| ACVR1 (ALK2) | STKR | TKL | 7a21 | B | B | 4-methyl-3-[4-(pyrrolidin-1-ylmethyl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | 12778 | |
| ACVR1 (ALK2) | STKR | TKL | 7c3g | A | A | ~{n}-[4-(4-methylpiperazin-1-yl)phenyl]-4-(2-pyridin-3-yl-6,7-dihydro-4~{h}-pyrazolo[5,1-c][1,4]oxazin-3-yl)pyrimidin-2-amine | Human | 13389 | |
| ACVR1 (ALK2) | STKR | TKL | 7c3g | A | B | ~{n}-[4-(4-methylpiperazin-1-yl)phenyl]-4-(2-pyridin-3-yl-6,7-dihydro-4~{h}-pyrazolo[5,1-c][1,4]oxazin-3-yl)pyrimidin-2-amine | Human | 13390 | |
| ACVR1 (ALK2) | STKR | TKL | 7c3g | B | A | ~{n}-[4-(4-methylpiperazin-1-yl)phenyl]-4-(2-pyridin-3-yl-6,7-dihydro-4~{h}-pyrazolo[5,1-c][1,4]oxazin-3-yl)pyrimidin-2-amine | Human | 13392 | |
| ACVR1 (ALK2) | STKR | TKL | 7c3g | B | B | ~{n}-[4-(4-methylpiperazin-1-yl)phenyl]-4-(2-pyridin-3-yl-6,7-dihydro-4~{h}-pyrazolo[5,1-c][1,4]oxazin-3-yl)pyrimidin-2-amine | Human | 13391 | |
| ACVR1 (ALK2) | STKR | TKL | 7nns | B | A | momelotinib | Human | 13465 | |
| ACVR1 (ALK2) | STKR | TKL | 7nns | B | B | momelotinib | Human | 13464 | |
| ACVR1 (ALK2) | STKR | TKL | 8c7w | A | A | 6-methyl-9-piperazin-1-yl-4-(3,4,5-trimethoxyphenyl)-5,7-dihydropyrido[4,3-d][2]benzazepine | Human | 14608 | |
| ACVR1 (ALK2) | STKR | TKL | 8c7w | A | B | 6-methyl-9-piperazin-1-yl-4-(3,4,5-trimethoxyphenyl)-5,7-dihydropyrido[4,3-d][2]benzazepine | Human | 14609 | |
| ACVR1 (ALK2) | STKR | TKL | 8c7z | A | A | 9-piperazin-1-yl-4-(3,4,5-trimethoxyphenyl)-5,6-dihydro-[1]benzoxepino[5,4-c]pyridine | Human | 14605 | |
| ACVR1 (ALK2) | STKR | TKL | 8c7z | A | B | 9-piperazin-1-yl-4-(3,4,5-trimethoxyphenyl)-5,6-dihydro-[1]benzoxepino[5,4-c]pyridine | Human | 14604 | |
| ACVR1 (ALK2) | STKR | TKL | 8pod | A | | 6-(4-piperazin-1-ylphenyl)-3-quinolin-4-yl-furo[3,2-b]pyridine | Human | 15314 | |
| ACVR1 (ALK2) | STKR | TKL | 8r7g | A | A | 2-fluoranyl-6-methoxy-4-[4-methyl-5-[4-(4-propan-2-ylpiperazin-1-yl)phenyl]pyridin-3-yl]benzamide | Human | 15267 | |
| ACVR1 (ALK2) | STKR | TKL | 8r7g | A | B | 2-fluoranyl-6-methoxy-4-[4-methyl-5-[4-(4-propan-2-ylpiperazin-1-yl)phenyl]pyridin-3-yl]benzamide | Human | 15266 | |
| ACVR2A (ACTR2) | STKR | TKL | 3q4t | A | A | 6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine | Human | 2682 | |
| ACVR2A (ACTR2) | STKR | TKL | 3q4t | A | B | 6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine | Human | 2686 | |
| ACVR2A (ACTR2) | STKR | TKL | 3q4t | B | A | 6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine | Human | 2680 | |
| ACVR2A (ACTR2) | STKR | TKL | 3q4t | B | B | 6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine | Human | 2684 | |
| ACVR2A (ACTR2) | STKR | TKL | 3soc | A | A | [4-({4-[(5-cyclopropyl-1h-pyrazol-3-yl)amino]quinazolin-2-yl}imino)cyclohexa-2,5-dien-1-yl]acetonitrile | Human | 2675 | |
| ACVR2A (ACTR2) | STKR | TKL | 3soc | A | B | [4-({4-[(5-cyclopropyl-1h-pyrazol-3-yl)amino]quinazolin-2-yl}imino)cyclohexa-2,5-dien-1-yl]acetonitrile | Human | 2676 | |
| ACVR2A (ACTR2) | STKR | TKL | 3soc | B | A | [4-({4-[(5-cyclopropyl-1h-pyrazol-3-yl)amino]quinazolin-2-yl}imino)cyclohexa-2,5-dien-1-yl]acetonitrile | Human | 2677 | |
| ACVR2A (ACTR2) | STKR | TKL | 3soc | B | B | [4-({4-[(5-cyclopropyl-1h-pyrazol-3-yl)amino]quinazolin-2-yl}imino)cyclohexa-2,5-dien-1-yl]acetonitrile | Human | 2685 | |
| ACVR2A (ACTR2) | STKR | TKL | 4asx | A | A | 7,8-bis(chloranyl)-9-methyl-3,4-dihydro-2h-pyrido[3,4-b]indol-1-one | Human | 2678 | |
| ACVR2A (ACTR2) | STKR | TKL | 4asx | A | B | 7,8-bis(chloranyl)-9-methyl-3,4-dihydro-2h-pyrido[3,4-b]indol-1-one | Human | 2681 | |
| ACVR2A (ACTR2) | STKR | TKL | 4asx | B | A | 7,8-bis(chloranyl)-9-methyl-3,4-dihydro-2h-pyrido[3,4-b]indol-1-one | Human | 2683 | |
| ACVR2A (ACTR2) | STKR | TKL | 4asx | B | B | 7,8-bis(chloranyl)-9-methyl-3,4-dihydro-2h-pyrido[3,4-b]indol-1-one | Human | 2679 | |
| ACVR2B (ACTR2B) | STKR | TKL | 2qlu | A | | adenine | Human | 2940 | |
| ACVRL1 (ALK1) | STKR | TKL | 3my0 | A | | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | 1266 | |
| ACVRL1 (ALK1) | STKR | TKL | 3my0 | B | | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | 1273 | |
| ACVRL1 (ALK1) | STKR | TKL | 3my0 | C | | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | 1269 | |
| ACVRL1 (ALK1) | STKR | TKL | 3my0 | D | | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | 1258 | |
| ACVRL1 (ALK1) | STKR | TKL | 3my0 | E | | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | 1263 | |
| ACVRL1 (ALK1) | STKR | TKL | 3my0 | F | | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | 1276 | |
| ACVRL1 (ALK1) | STKR | TKL | 3my0 | G | | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | 1272 | |
| ACVRL1 (ALK1) | STKR | TKL | 3my0 | H | | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | 1260 | |
| ACVRL1 (ALK1) | STKR | TKL | 3my0 | I | | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | 1261 | |
| ACVRL1 (ALK1) | STKR | TKL | 3my0 | J | | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | 1277 | |
| ACVRL1 (ALK1) | STKR | TKL | 3my0 | K | | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | 1267 | |
| ACVRL1 (ALK1) | STKR | TKL | 3my0 | L | | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | 1265 | |
| ACVRL1 (ALK1) | STKR | TKL | 3my0 | M | | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | 1268 | |
| ACVRL1 (ALK1) | STKR | TKL | 3my0 | N | | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | 1257 | |
| ACVRL1 (ALK1) | STKR | TKL | 3my0 | O | | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | 1262 | |
| ACVRL1 (ALK1) | STKR | TKL | 3my0 | P | | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | 1270 | |
| ACVRL1 (ALK1) | STKR | TKL | 3my0 | Q | | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | 1274 | |
| ACVRL1 (ALK1) | STKR | TKL | 3my0 | R | | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | 1256 | |
| ACVRL1 (ALK1) | STKR | TKL | 3my0 | S | | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | 1259 | |
| ACVRL1 (ALK1) | STKR | TKL | 3my0 | T | | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | 1264 | |
| ACVRL1 (ALK1) | STKR | TKL | 3my0 | U | | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | 1278 | |
| ACVRL1 (ALK1) | STKR | TKL | 3my0 | V | | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | 1271 | |
| ACVRL1 (ALK1) | STKR | TKL | 3my0 | W | | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | 1255 | |
| ACVRL1 (ALK1) | STKR | TKL | 3my0 | X | | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | 1275 | |
| AKT1 | Akt | AGC | 3cqu | A | A | n-[2-(5-methyl-4h-1,2,4-triazol-3-yl)phenyl]-7h-pyrrolo[2,3-d]pyrimidin-4-amine | Human | 6764 | |
| AKT1 | Akt | AGC | 3cqu | A | B | n-[2-(5-methyl-4h-1,2,4-triazol-3-yl)phenyl]-7h-pyrrolo[2,3-d]pyrimidin-4-amine | Human | 6762 | |
| AKT1 | Akt | AGC | 3cqw | A | A | 5-(5-chloro-7h-pyrrolo[2,3-d]pyrimidin-4-yl)-4,5,6,7-tetrahydro-1h-imidazo[4,5-c]pyridine | Human | 6763 | |
| AKT1 | Akt | AGC | 3cqw | A | B | 5-(5-chloro-7h-pyrrolo[2,3-d]pyrimidin-4-yl)-4,5,6,7-tetrahydro-1h-imidazo[4,5-c]pyridine | Human | 6765 | |
| AKT1 | Akt | AGC | 3mv5 | A | A | (3r)-1-(5-methyl-7h-pyrrolo[2,3-d]pyrimidin-4-yl)pyrrolidin-3-amine | Human | 2537 | |
| AKT1 | Akt | AGC | 3mv5 | A | B | (3r)-1-(5-methyl-7h-pyrrolo[2,3-d]pyrimidin-4-yl)pyrrolidin-3-amine | Human | 2532 | |
| AKT1 | Akt | AGC | 3mvh | A | A | n-{[(3s)-3-amino-1-(5-ethyl-7h-pyrrolo[2,3-d]pyrimidin-4-yl)pyrrolidin-3-yl]methyl}-2,4-difluorobenzamide | Human | 2538 | |
| AKT1 | Akt | AGC | 3mvh | A | B | n-{[(3s)-3-amino-1-(5-ethyl-7h-pyrrolo[2,3-d]pyrimidin-4-yl)pyrrolidin-3-yl]methyl}-2,4-difluorobenzamide | Human | 2531 | |
| AKT1 | Akt | AGC | 3o96 | A | | - | Human | 2545 | |
| AKT1 | Akt | AGC | 3ocb | A | | (2s)-2-(4-chlorobenzyl)-3-oxo-3-[4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)piperazin-1-yl]propan-1-amine | Human | 2548 | |
| AKT1 | Akt | AGC | 3ocb | B | | (2s)-2-(4-chlorobenzyl)-3-oxo-3-[4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)piperazin-1-yl]propan-1-amine | Human | 2534 | |
| AKT1 | Akt | AGC | 3ow4 | A | | (2r)-3-(1h-indol-3-yl)-1-{4-[(5s)-5-methyl-5,7-dihydrothieno[3,4-d]pyrimidin-4-yl]piperazin-1-yl}-1-oxopropan-2-amine | Human | 2547 | |
| AKT1 | Akt | AGC | 3ow4 | B | | (2r)-3-(1h-indol-3-yl)-1-{4-[(5s)-5-methyl-5,7-dihydrothieno[3,4-d]pyrimidin-4-yl]piperazin-1-yl}-1-oxopropan-2-amine | Human | 2533 | |
| AKT1 | Akt | AGC | 3qkk | A | | n-(2-ethoxyethyl)-n-{(2s)-2-hydroxy-3-[(2r)-6-hydroxy-4-oxo-3,4-dihydro-1'h-spiro[chromene-2,3'-piperidin]-1'-yl]propyl}-2,6-dimethylbenzenesulfonamide | Human | 2535 | |
| AKT1 | Akt | AGC | 3qkl | A | | n-{(2s)-3-[(3s)-8',9'-dihydro-1h,3'h-spiro[piperidine-3,7'-pyrano[3,2-e]indazol]-1-yl]-2-hydroxypropyl}-n-(2-ethoxyethyl)-2,6-dimethylbenzenesulfonamide | Human | 2544 | |
| AKT1 | Akt | AGC | 3qkm | A | | n-(2-ethoxyethyl)-n-{(2s)-2-hydroxy-3-[(5r)-2-(quinazolin-4-yl)-2,7-diazaspiro[4.5]dec-7-yl]propyl}-2,6-dimethylbenzenesulfonamide | Human | 2546 | |
| AKT1 | Akt | AGC | 4ejn | A | | - | Human | 2542 | |
| AKT1 | Akt | AGC | 4ekk | A | | phosphoaminophosphonic acid-adenylate ester | Human | 2541 | |
| AKT1 | Akt | AGC | 4ekk | B | | phosphoaminophosphonic acid-adenylate ester | Human | 2539 | |
| AKT1 | Akt | AGC | 4ekl | A | | (2s)-2-(4-chlorophenyl)-1-{4-[(5r,7r)-7-hydroxy-5-methyl-6,7-dihydro-5h-cyclopenta[d]pyrimidin-4-yl]piperazin-1-yl}-3-(propan-2-ylamino)propan-1-one | Human | 2540 | |
| AKT1 | Akt | AGC | 4gv1 | A | A | 4-amino-n-[(1s)-1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide | Human | 2543 | |
| AKT1 | Akt | AGC | 4gv1 | A | B | 4-amino-n-[(1s)-1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide | Human | 2536 | |
| AKT1 | Akt | AGC | 5kcv | A | | 3-[3-[4-(1-azanylcyclobutyl)phenyl]-5-phenyl-imidazo[4,5-b]pyridin-2-yl]pyridin-2-amine | Human | 6708 | |
| AKT1 | Akt | AGC | 6buu | A | A | - | Human | 10432 | |
| AKT1 | Akt | AGC | 6buu | A | B | - | Human | 10433 | |
| AKT1 | Akt | AGC | 6buu | A | C | - | Human | 10438 | |
| AKT1 | Akt | AGC | 6buu | B | A | - | Human | 10430 | |
| AKT1 | Akt | AGC | 6buu | B | B | - | Human | 10439 | |
| AKT1 | Akt | AGC | 6buu | B | C | - | Human | 10428 | |
| AKT1 | Akt | AGC | 6ccy | A | A | (5r)-4-(4-{4-[4-fluoro-3-(trifluoromethyl)phenyl]-1-[2-(pyrrolidin-1-yl)ethyl]-1h-imidazol-2-yl}piperidin-1-yl)-5-methyl-5,8-dihydropyrido[2,3-d]pyrimidin-7(6h)-one | Human | 9868 | |
| AKT1 | Akt | AGC | 6ccy | A | B | (5r)-4-(4-{4-[4-fluoro-3-(trifluoromethyl)phenyl]-1-[2-(pyrrolidin-1-yl)ethyl]-1h-imidazol-2-yl}piperidin-1-yl)-5-methyl-5,8-dihydropyrido[2,3-d]pyrimidin-7(6h)-one | Human | 9869 | |
| AKT1 | Akt | AGC | 6hhf | A | | borussertib | Human | 10970 | |
| AKT1 | Akt | AGC | 6hhg | A | | ~{n}-[2-chloranyl-5-[[1-[[4-(5-oxidanylidene-3-phenyl-6~{h}-1,6-naphthyridin-2-yl)phenyl]methyl]piperidin-4-yl]carbamoylamino]phenyl]propanamide | Human | 10916 | |
| AKT1 | Akt | AGC | 6hhh | A | | ~{n}-[4-[4-[[4-(5-oxidanylidene-3-phenyl-6~{h}-1,6-naphthyridin-2-yl)phenyl]methyl]piperazin-1-yl]phenyl]propanamide | Human | 10915 | |
| AKT1 | Akt | AGC | 6hhi | A | | ~{n}-[1-[[4-(5-oxidanylidene-3-phenyl-6~{h}-1,6-naphthyridin-2-yl)phenyl]methyl]piperidin-4-yl]-3-(propanoylamino)benzamide | Human | 10913 | |
| AKT1 | Akt | AGC | 6hhj | A | | ~{n}-[1-methyl-2-oxidanylidene-3-[1-[[4-(5-oxidanylidene-3-phenyl-6~{h}-1,6-naphthyridin-2-yl)phenyl]methyl]piperidin-4-yl]benzimidazol-5-yl]propanamide | Human | 10914 | |
| AKT1 | Akt | AGC | 6npz | A | A | - | Human | 10880 | |
| AKT1 | Akt | AGC | 6npz | A | B | - | Human | 10882 | |
| AKT1 | Akt | AGC | 6npz | B | A | - | Human | 10881 | |
| AKT1 | Akt | AGC | 6npz | B | B | - | Human | 10879 | |
| AKT1 | Akt | AGC | 6s9w | A | A | ~{n}-[3-[1-[[4-(5-methyl-6-oxidanylidene-3-phenyl-1~{h}-pyrazin-2-yl)phenyl]methyl]piperidin-4-yl]-2-oxidanylidene-1~{h}-benzimidazol-5-yl]propanamide | Human | 11748 | |
| AKT1 | Akt | AGC | 6s9w | A | B | ~{n}-[3-[1-[[4-(5-methyl-6-oxidanylidene-3-phenyl-1~{h}-pyrazin-2-yl)phenyl]methyl]piperidin-4-yl]-2-oxidanylidene-1~{h}-benzimidazol-5-yl]propanamide | Human | 11747 | |
| AKT1 | Akt | AGC | 6s9x | A | | ~{n}-[3-[1-[[4-[5-[(4-hydroxyphenyl)methyl]-6-oxidanylidene-2-phenyl-1~{h}-pyrazin-3-yl]phenyl]methyl]piperidin-4-yl]-2-oxidanylidene-1~{h}-benzimidazol-5-yl]propanamide | Human | 11746 | |
| AKT1 | Akt | AGC | 7apj | A | | - | Human | 13854 | |
| AKT1 | Akt | AGC | 7nh4 | A | A | ~{n}-[3-[1-[[4-[5-(hydroxymethyl)-3-phenyl-pyridin-2-yl]phenyl]methyl]piperidin-4-yl]-2-oxidanylidene-1~{h}-benzimidazol-5-yl]propanamide | Human | 13865 | |
| AKT1 | Akt | AGC | 7nh4 | A | B | ~{n}-[3-[1-[[4-[5-(hydroxymethyl)-3-phenyl-pyridin-2-yl]phenyl]methyl]piperidin-4-yl]-2-oxidanylidene-1~{h}-benzimidazol-5-yl]propanamide | Human | 13866 | |
| AKT1 | Akt | AGC | 7nh5 | A | A | ~{n}-methyl-6-[4-[[4-[2-oxidanylidene-6-(propanoylamino)-3~{h}-benzimidazol-1-yl]piperidin-1-yl]methyl]phenyl]-5-phenyl-pyridine-3-carboxamide | Human | 13867 | |
| AKT1 | Akt | AGC | 7nh5 | A | B | ~{n}-methyl-6-[4-[[4-[2-oxidanylidene-6-(propanoylamino)-3~{h}-benzimidazol-1-yl]piperidin-1-yl]methyl]phenyl]-5-phenyl-pyridine-3-carboxamide | Human | 13868 | |
| AKT1 | Akt | AGC | 8uvy | A | A | 4-{2-[({4-[(2p)-2-(2-aminopyridin-3-yl)-5-phenyl-3h-imidazo[4,5-b]pyridin-3-yl]phenyl}methyl)amino]ethyl}-2-hydroxybenzaldehyde | Human | 15378 | |
| AKT1 | Akt | AGC | 8uvy | A | B | 4-{2-[({4-[(2p)-2-(2-aminopyridin-3-yl)-5-phenyl-3h-imidazo[4,5-b]pyridin-3-yl]phenyl}methyl)amino]ethyl}-2-hydroxybenzaldehyde | Human | 15381 | |
| AKT1 | Akt | AGC | 8uw2 | A | A | 4-{2-[({4-[(2p)-2-(2-aminopyridin-3-yl)-5-phenyl-3h-imidazo[4,5-b]pyridin-3-yl]phenyl}methyl)amino]ethyl}-2-hydroxybenzaldehyde | Human | 15379 | |
| AKT1 | Akt | AGC | 8uw2 | A | B | 4-{2-[({4-[(2p)-2-(2-aminopyridin-3-yl)-5-phenyl-3h-imidazo[4,5-b]pyridin-3-yl]phenyl}methyl)amino]ethyl}-2-hydroxybenzaldehyde | Human | 15380 | |
| AKT1 | Akt | AGC | 8uw7 | A | A | 4-{2-[({4-[(2p)-2-(2-aminopyridin-3-yl)-5-phenyl-3h-imidazo[4,5-b]pyridin-3-yl]phenyl}methyl)amino]ethyl}-2-hydroxybenzaldehyde | Human | 15385 | |
| AKT1 | Akt | AGC | 8uw7 | A | B | 4-{2-[({4-[(2p)-2-(2-aminopyridin-3-yl)-5-phenyl-3h-imidazo[4,5-b]pyridin-3-yl]phenyl}methyl)amino]ethyl}-2-hydroxybenzaldehyde | Human | 15382 | |
| AKT1 | Akt | AGC | 8uw9 | A | A | n-({4-[(2p)-2-(2-aminopyridin-3-yl)-5-phenyl-3h-imidazo[4,5-b]pyridin-3-yl]phenyl}methyl)-2-(2-fluoro-4-formyl-3-hydroxyphenyl)acetamide | Human | 15383 | |
| AKT1 | Akt | AGC | 8uw9 | A | B | n-({4-[(2p)-2-(2-aminopyridin-3-yl)-5-phenyl-3h-imidazo[4,5-b]pyridin-3-yl]phenyl}methyl)-2-(2-fluoro-4-formyl-3-hydroxyphenyl)acetamide | Human | 15384 | |
| AKT2 | Akt | AGC | 1gzk | A | | - | Human | 1916 | |
| AKT2 | Akt | AGC | 1gzn | A | | - | Human | 1915 | |
| AKT2 | Akt | AGC | 1gzo | A | | - | Human | 1914 | |
| AKT2 | Akt | AGC | 1mrv | A | | - | Human | 1917 | |
| AKT2 | Akt | AGC | 1mry | A | | - | Human | 1907 | |
| AKT2 | Akt | AGC | 1o6k | A | | phosphoaminophosphonic acid-adenylate ester | Human | 1923 | |
| AKT2 | Akt | AGC | 1o6l | A | | phosphoaminophosphonic acid-adenylate ester | Human | 1906 | |
| AKT2 | Akt | AGC | 2jdo | A | | isoquinoline-5-sulfonic acid (2-(2-(4-chlorobenzyloxy)ethylamino)ethyl)amide | Human | 1922 | |
| AKT2 | Akt | AGC | 2jdr | A | | (2s)-1-(1h-indol-3-yl)-3-{[5-(3-methyl-1h-indazol-5-yl)pyridin-3-yl]oxy}propan-2-amine | Human | 1918 | |
| AKT2 | Akt | AGC | 2uw9 | A | | 4-(4-chlorophenyl)-4-[4-(1h-pyrazol-4-yl)phenyl]piperidine | Human | 1919 | |
| AKT2 | Akt | AGC | 2x39 | A | | 4-amino-n-(4-chlorobenzyl)-1-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide | Human | 1913 | |
| AKT2 | Akt | AGC | 2xh5 | A | | 4-(4-tert-butylbenzyl)-1-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-aminium | Human | 1924 | |
| AKT2 | Akt | AGC | 3d0e | A | | 4-{2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3s)-piperidin-3-ylmethoxy]-1h-imidazo[4,5-c]pyridin-4-yl}-2-methylbut-3-yn-2-ol | Human | 1912 | |
| AKT2 | Akt | AGC | 3d0e | B | | 4-{2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3s)-piperidin-3-ylmethoxy]-1h-imidazo[4,5-c]pyridin-4-yl}-2-methylbut-3-yn-2-ol | Human | 1920 | |
| AKT2 | Akt | AGC | 3e87 | A | A | n-[(1s)-2-amino-1-phenylethyl]-5-(1h-pyrrolo[2,3-b]pyridin-4-yl)thiophene-2-carboxamide | Human | 1910 | |
| AKT2 | Akt | AGC | 3e87 | A | B | n-[(1s)-2-amino-1-phenylethyl]-5-(1h-pyrrolo[2,3-b]pyridin-4-yl)thiophene-2-carboxamide | Human | 1911 | |
| AKT2 | Akt | AGC | 3e87 | B | A | n-[(1s)-2-amino-1-phenylethyl]-5-(1h-pyrrolo[2,3-b]pyridin-4-yl)thiophene-2-carboxamide | Human | 1909 | |
| AKT2 | Akt | AGC | 3e87 | B | B | n-[(1s)-2-amino-1-phenylethyl]-5-(1h-pyrrolo[2,3-b]pyridin-4-yl)thiophene-2-carboxamide | Human | 1903 | |
| AKT2 | Akt | AGC | 3e88 | A | | 4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-6-{[(2r)-2-amino-3-phenylpropyl]oxy}-1-ethyl-1h-imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-ol | Human | 1908 | |
| AKT2 | Akt | AGC | 3e88 | B | | 4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-6-{[(2r)-2-amino-3-phenylpropyl]oxy}-1-ethyl-1h-imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-ol | Human | 1905 | |
| AKT2 | Akt | AGC | 3e8d | A | A | 4-[2-(4-amino-2,5-dihydro-1,2,5-oxadiazol-3-yl)-6-{[(1s)-3-amino-1-phenylpropyl]oxy}-1-ethyl-1h-imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-ol | Human | 1921 | |
| AKT2 | Akt | AGC | 3e8d | A | B | 4-[2-(4-amino-2,5-dihydro-1,2,5-oxadiazol-3-yl)-6-{[(1s)-3-amino-1-phenylpropyl]oxy}-1-ethyl-1h-imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-ol | Human | 1926 | |
| AKT2 | Akt | AGC | 3e8d | B | A | 4-[2-(4-amino-2,5-dihydro-1,2,5-oxadiazol-3-yl)-6-{[(1s)-3-amino-1-phenylpropyl]oxy}-1-ethyl-1h-imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-ol | Human | 1925 | |
| AKT2 | Akt | AGC | 3e8d | B | B | 4-[2-(4-amino-2,5-dihydro-1,2,5-oxadiazol-3-yl)-6-{[(1s)-3-amino-1-phenylpropyl]oxy}-1-ethyl-1h-imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-ol | Human | 1904 | |
| AKT2 | Akt | AGC | 8q61 | A | A | 6-[4-(1-azanyl-3-methyl-3-oxidanyl-cyclobutyl)phenyl]-7-phenyl-1-propyl-pyrido[2,3-b][1,4]oxazin-2-one | Human | 14978 | |
| AKT2 | Akt | AGC | 8q61 | A | B | 6-[4-(1-azanyl-3-methyl-3-oxidanyl-cyclobutyl)phenyl]-7-phenyl-1-propyl-pyrido[2,3-b][1,4]oxazin-2-one | Human | 14979 | |
| AKT2 | Akt | AGC | 9c1w | A | | 4-{2-[({4-[(2p)-2-(2-aminopyridin-3-yl)-5-phenyl-3h-imidazo[4,5-b]pyridin-3-yl]phenyl}methyl)amino]ethyl}-2-hydroxybenzaldehyde | Human | 15393 | |
| ALK | ALK | TK | 2xb7 | A | | 5-chloro-n-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]-n'-(2-propan-2-ylsulfonylphenyl)pyrimidine-2,4-diamine | Human | 5365 | |
| ALK | ALK | TK | 2xba | A | | 5-[(2r)-2-hydroxy-2-phenylacetyl]-3-({[4-(4-methylpiperazin-1-yl)phenyl]carbonyl}amino)-1,6-dihydropyrrolo[3,4-c]pyrazol-5-ium | Human | 5408 | |
| ALK | ALK | TK | 2xp2 | A | | 3-[(1r)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-yl-1h-pyrazol-4-yl)pyridin-2-amine | Human | 5394 | |
| ALK | ALK | TK | 2yfx | A | | 3-[(1r)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-yl-1h-pyrazol-4-yl)pyridin-2-amine | Human | 5402 | |
| ALK | ALK | TK | 2yhv | A | | - | Human | 5384 | |
| ALK | ALK | TK | 2yjr | A | A | - | Human | 5399 | |
| ALK | ALK | TK | 2yjr | A | B | - | Human | 5380 | |
| ALK | ALK | TK | 2yjs | A | | - | Human | 5373 | |
| ALK | ALK | TK | 3aox | A | A | 9-ethyl-6,6-dimethyl-8-[4-(morpholin-4-yl)piperidin-1-yl]-11-oxo-6,11-dihydro-5h-benzo[b]carbazole-3-carbonitrile | Human | 5387 | |
| ALK | ALK | TK | 3aox | A | B | 9-ethyl-6,6-dimethyl-8-[4-(morpholin-4-yl)piperidin-1-yl]-11-oxo-6,11-dihydro-5h-benzo[b]carbazole-3-carbonitrile | Human | 5370 | |
| ALK | ALK | TK | 3l9p | A | A | - | Human | 5363 | |
| ALK | ALK | TK | 3l9p | A | B | - | Human | 5375 | |
| ALK | ALK | TK | 3lcs | A | A | staurosporine | Human | 5381 | |
| ALK | ALK | TK | 3lcs | A | B | staurosporine | Human | 5376 | |
| ALK | ALK | TK | 3lct | A | A | adenosine-5'-diphosphate | Human | 5393 | |
| ALK | ALK | TK | 3lct | A | B | adenosine-5'-diphosphate | Human | 5400 | |
| ALK | ALK | TK | 4anl | A | | - | Human | 5385 | |
| ALK | ALK | TK | 4anq | A | | 3-[(1r)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-yl-1h-pyrazol-4-yl)pyridin-2-amine | Human | 5368 | |
| ALK | ALK | TK | 4ans | A | | 3-[(1r)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-yl-1h-pyrazol-4-yl)pyridin-2-amine | Human | 5374 | |
| ALK | ALK | TK | 4ccb | A | | 3-[(1r)-1-[5-fluoranyl-2-(1,2,3-triazol-2-yl)phenyl]ethoxy]-5-(3-methyl-1h-pyrazol-4-yl)pyridin-2-amine | Human | 5390 | |
| ALK | ALK | TK | 4ccu | A | | 2-(5-(6-amino-5-((r)-1-(5-fluoro-2-(2h-1,2,3-triazol-2-yl)phenyl)ethoxy)pyridin-3-yl)-4-methylthiazol-2-yl)propan-2-ol | Human | 5396 | |
| ALK | ALK | TK | 4cd0 | A | | (2r)-2-[5-(6-amino-5-{(1r)-1-[2-(1,3-dihydro-2h-1,2,3-triazol-2-yl)-5-fluorophenyl]ethoxy}pyridin-3-yl)-4-methyl-1,3-thiazol-2-yl]propane-1,2-diol | Human | 5407 | |
| ALK | ALK | TK | 4cli | A | | (10r)-7-amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2h-8,4-(metheno)pyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecine-3-carbonitrile | Human | 5405 | |
| ALK | ALK | TK | 4clj | A | | (10r)-7-amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2h-8,4-(metheno)pyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecine-3-carbonitrile | Human | 5369 | |
| ALK | ALK | TK | 4cmo | A | | 2-[(1r)-1-{[3-amino-6-(2-methoxypyridin-3-yl)pyrazin-2-yl]oxy}ethyl]-4-fluoro-n-methylbenzamide | Human | 5391 | |
| ALK | ALK | TK | 4cmt | A | | 3-{(1r)-1-[2-(1,3-dihydro-2h-1,2,3-triazol-2-yl)-5-fluorophenyl]ethoxy}-5-[3-(methylsulfonyl)phenyl]pyridin-2-amine | Human | 5371 | |
| ALK | ALK | TK | 4cmu | A | | (10r)-7-amino-12-fluoro-1,3,10,16-tetramethyl-16,17-dihydro-1h-8,4-(metheno)pyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecin-15(10h)-one | Human | 5398 | |
| ALK | ALK | TK | 4cnh | A | | 3-[(1r)-1-(5-fluoro-2-methoxyphenyl)ethoxy]-5-(1-methyl-1h-1,2,3-triazol-5-yl)pyridin-2-amine | Human | 5388 | |
| ALK | ALK | TK | 4cnh | B | | 3-[(1r)-1-(5-fluoro-2-methoxyphenyl)ethoxy]-5-(1-methyl-1h-1,2,3-triazol-5-yl)pyridin-2-amine | Human | 5378 | |
| ALK | ALK | TK | 4ctb | A | | (5r)-8-amino-3-fluoro-5,19-dimethyl-20-oxo-5,18,19,20-tetrahydro-11,7-(azeno)pyrido[2',1':2,3]imidazo[4,5-h][2,5,11]benzoxadiazacyclotetradecine-14-carbonitrile | Human | 5395 | |
| ALK | ALK | TK | 4ctc | A | | (10r)-7-amino-3-cyclopropyl-12-fluoro-1,10,16-trimethyl-16,17-dihydro-1h-8,4-(metheno)pyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecin-15(10h)-one | Human | 5364 | |
| ALK | ALK | TK | 4dce | A | | (3s)-n-(4-methylbenzyl)-1-{2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl}piperidine-3-carboxamide | Human | 5379 | |
| ALK | ALK | TK | 4dce | B | | (3s)-n-(4-methylbenzyl)-1-{2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl}piperidine-3-carboxamide | Human | 5372 | |
| ALK | ALK | TK | 4fnw | A | | - | Human | 5403 | |
| ALK | ALK | TK | 4fnx | A | | - | Human | 5366 | |
| ALK | ALK | TK | 4fny | A | | n-(4-chlorophenyl)-5-[(6,7-dimethoxyquinolin-4-yl)oxy]-1,3-benzoxazol-2-amine | Human | 5367 | |
| ALK | ALK | TK | 4fnz | A | | (3s)-n-[3-(trifluoromethoxy)benzyl]-1-{2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl}piperidine-3-carboxamide | Human | 5397 | |
| ALK | ALK | TK | 4fob | A | | n-{1-[cis-4-(hydroxymethyl)cyclohexyl]-5-(piperidin-1-ylmethyl)-1h-benzimidazol-2-yl}-3-(prop-2-en-1-ylsulfamoyl)benzamide | Human | 5377 | |
| ALK | ALK | TK | 4foc | A | | methyl cis-4-[2-(benzoylamino)-6-(piperidin-1-ylmethyl)-1h-benzimidazol-1-yl]cyclohexanecarboxylate | Human | 5392 | |
| ALK | ALK | TK | 4fod | A | A | 4-fluoro-n-{(2e)-6-{[4-(2-hydroxypropan-2-yl)piperidin-1-yl]methyl}-1-[cis-4-(propan-2-ylcarbamoyl)cyclohexyl]-1,3-dihydro-2h-benzimidazol-2-ylidene}benzamide | Human | 5383 | |
| ALK | ALK | TK | 4fod | A | B | 4-fluoro-n-{(2e)-6-{[4-(2-hydroxypropan-2-yl)piperidin-1-yl]methyl}-1-[cis-4-(propan-2-ylcarbamoyl)cyclohexyl]-1,3-dihydro-2h-benzimidazol-2-ylidene}benzamide | Human | 5404 | |
| ALK | ALK | TK | 4joa | A | A | 3-[1-(2,5-difluorobenzyl)-1h-pyrazol-4-yl]-5-(1-methyl-1h-pyrazol-4-yl)-1h-pyrrolo[2,3-b]pyridine | Human | 5389 | |
| ALK | ALK | TK | 4mkc | A | A | 5-chloro-n~2~-[5-methyl-4-(piperidin-4-yl)-2-(propan-2-yloxy)phenyl]-n~4~-[2-(propan-2-ylsulfonyl)phenyl]pyrimidine-2,4-diamine | Human | 5401 | |
| ALK | ALK | TK | 4mkc | A | B | 5-chloro-n~2~-[5-methyl-4-(piperidin-4-yl)-2-(propan-2-yloxy)phenyl]-n~4~-[2-(propan-2-ylsulfonyl)phenyl]pyrimidine-2,4-diamine | Human | 5386 | |
| ALK | ALK | TK | 4tt7 | A | A | - | Human | 5406 | |
| ALK | ALK | TK | 4tt7 | A | B | - | Human | 5382 | |
| ALK | ALK | TK | 4z55 | A | A | n~6~-[5-methyl-4-(1-methylpiperidin-4-yl)-2-(propan-2-yloxy)phenyl]-n~4~-[2-(propan-2-ylsulfonyl)phenyl]-2h-pyrazolo[3,4-d]pyrimidine-4,6-diamine | Human | 6393 | |
| ALK | ALK | TK | 4z55 | A | B | n~6~-[5-methyl-4-(1-methylpiperidin-4-yl)-2-(propan-2-yloxy)phenyl]-n~4~-[2-(propan-2-ylsulfonyl)phenyl]-2h-pyrazolo[3,4-d]pyrimidine-4,6-diamine | Human | 6392 | |
| ALK | ALK | TK | 5a9u | A | A | (10r)-7-amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2h-8,4-(metheno)pyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecine-3-carbonitrile | Human | 6692 | |
| ALK | ALK | TK | 5a9u | A | B | (10r)-7-amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2h-8,4-(metheno)pyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecine-3-carbonitrile | Human | 6685 | |
| ALK | ALK | TK | 5aa8 | A | A | (10r)-7-amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2h-8,4-(metheno)pyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecine-3-carbonitrile | Human | 6688 | |
| ALK | ALK | TK | 5aa8 | A | B | (10r)-7-amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2h-8,4-(metheno)pyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecine-3-carbonitrile | Human | 6684 | |
| ALK | ALK | TK | 5aa9 | A | A | (10r)-7-amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2h-8,4-(metheno)pyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecine-3-carbonitrile | Human | 6682 | |
| ALK | ALK | TK | 5aa9 | A | B | (10r)-7-amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2h-8,4-(metheno)pyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecine-3-carbonitrile | Human | 6687 | |
| ALK | ALK | TK | 5aaa | A | A | 3-[(1r)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-yl-1h-pyrazol-4-yl)pyridin-2-amine | Human | 6691 | |
| ALK | ALK | TK | 5aaa | A | B | 3-[(1r)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-yl-1h-pyrazol-4-yl)pyridin-2-amine | Human | 6683 | |
| ALK | ALK | TK | 5aab | A | A | 3-[(1r)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-yl-1h-pyrazol-4-yl)pyridin-2-amine | Human | 6689 | |
| ALK | ALK | TK | 5aab | A | B | 3-[(1r)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-yl-1h-pyrazol-4-yl)pyridin-2-amine | Human | 6681 | |
| ALK | ALK | TK | 5aac | A | A | 3-[(1r)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-yl-1h-pyrazol-4-yl)pyridin-2-amine | Human | 6690 | |
| ALK | ALK | TK | 5aac | A | B | 3-[(1r)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-yl-1h-pyrazol-4-yl)pyridin-2-amine | Human | 6686 | |
| ALK | ALK | TK | 5fto | A | A | entrectinib | Human | 6520 | |
| ALK | ALK | TK | 5fto | A | B | entrectinib | Human | 6521 | |
| ALK | ALK | TK | 5ftq | A | A | n-[5-(3,5-difluorobenzyl)-1h-indazol-3-yl]-2-[(4-hydroxycyclohexyl)amino]-4-(4-methylpiperazin-1-yl) benzamide | Human | 6519 | |
| ALK | ALK | TK | 5ftq | A | B | n-[5-(3,5-difluorobenzyl)-1h-indazol-3-yl]-2-[(4-hydroxycyclohexyl)amino]-4-(4-methylpiperazin-1-yl) benzamide | Human | 6518 | |
| ALK | ALK | TK | 5imx | A | | 5-chloro-n~2~-{5-methyl-4-(1-methylpiperidin-4-yl)-2-[(propan-2-yl)oxy]phenyl}-n~4~-{1-methyl-3-[(propan-2-yl)sulfonyl]-1h-pyrazol-4-yl}pyrimidine-2,4-diamine | Human | 6604 | |
| ALK | ALK | TK | 5iug | A | A | n-[3-(4-{[(5-tert-butyl-1,2-oxazol-3-yl)carbamoyl]amino}-3-methylphenyl)-1h-pyrazol-5-yl]-4-[(4-methylpiperazin-1-yl)methyl]benzamide | Human | 6640 | |
| ALK | ALK | TK | 5iug | A | B | n-[3-(4-{[(5-tert-butyl-1,2-oxazol-3-yl)carbamoyl]amino}-3-methylphenyl)-1h-pyrazol-5-yl]-4-[(4-methylpiperazin-1-yl)methyl]benzamide | Human | 6639 | |
| ALK | ALK | TK | 5iuh | A | | 4-[(4-methylpiperazin-1-yl)methyl]-n-{3-[3-methyl-4-({[5-(propan-2-yl)-1,2-oxazol-3-yl]carbamoyl}amino)phenyl]-1h-pyrazol-5-yl}benzamide | Human | 6638 | |
| ALK | ALK | TK | 5iui | A | A | n-[3-(4-amino-3-methylphenyl)-1h-pyrazol-5-yl]-4-[(4-methylpiperazin-1-yl)methyl]benzamide | Human | 6641 | |
| ALK | ALK | TK | 5iui | A | B | n-[3-(4-amino-3-methylphenyl)-1h-pyrazol-5-yl]-4-[(4-methylpiperazin-1-yl)methyl]benzamide | Human | 6642 | |
| ALK | ALK | TK | 5kz0 | A | | 2-[(1~{r})-1-[2-azanyl-5-(1,3-dimethylpyrazol-4-yl)pyridin-3-yl]oxyethyl]-4-fluoranyl-~{n},~{n}-dimethyl-benzamide | Human | 6970 | |
| ALK | ALK | TK | 6cdt | A | | - | Human | 11263 | |
| ALK | ALK | TK | 6e0r | A | A | n-[(1s)-1-(5-fluoropyridin-2-yl)ethyl]-1-(5-methyl-1h-pyrazol-3-yl)-3-[(oxetan-3-yl)sulfonyl]-1h-pyrrolo[2,3-b]pyridin-6-amine | Human | 11268 | |
| ALK | ALK | TK | 6e0r | A | B | n-[(1s)-1-(5-fluoropyridin-2-yl)ethyl]-1-(5-methyl-1h-pyrazol-3-yl)-3-[(oxetan-3-yl)sulfonyl]-1h-pyrrolo[2,3-b]pyridin-6-amine | Human | 11266 | |
| ALK | ALK | TK | 6ebw | A | A | [6-{[(1s)-1-(5-fluoropyridin-2-yl)ethyl]amino}-1-(5-methyl-1h-pyrazol-3-yl)-1h-pyrrolo[2,3-b]pyridin-3-yl](morpholin-4-yl)methanone | Human | 11269 | |
| ALK | ALK | TK | 6ebw | A | B | [6-{[(1s)-1-(5-fluoropyridin-2-yl)ethyl]amino}-1-(5-methyl-1h-pyrazol-3-yl)-1h-pyrrolo[2,3-b]pyridin-3-yl](morpholin-4-yl)methanone | Human | 11264 | |
| ALK | ALK | TK | 6edl | A | A | n-[(1s)-1-(2,4-difluorophenyl)ethyl]-3-(5-methyl-1h-pyrazol-3-yl)imidazo[1,2-b]pyridazin-6-amine | Human | 11267 | |
| ALK | ALK | TK | 6edl | A | B | n-[(1s)-1-(2,4-difluorophenyl)ethyl]-3-(5-methyl-1h-pyrazol-3-yl)imidazo[1,2-b]pyridazin-6-amine | Human | 11265 | |
| ALK | ALK | TK | 6mx8 | A | A | 5-chloro-n~4~-[2-(dimethylphosphoryl)phenyl]-n~2~-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}pyrimidine-2,4-diamine | Human | 10798 | |
| ALK | ALK | TK | 6mx8 | A | B | 5-chloro-n~4~-[2-(dimethylphosphoryl)phenyl]-n~2~-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}pyrimidine-2,4-diamine | Human | 10799 | |
| ALK | ALK | TK | 7btt | A | A | 2-(dimethylamino)-1-[5-methoxy-6-[[4-[(2-propan-2-ylsulfonylphenyl)amino]-5h-pyrrolo[3,2-d]pyrimidin-2-yl]amino]-2,3-dihydroindol-1-yl]ethanone | Human | 13484 | |
| ALK | ALK | TK | 7btt | A | B | 2-(dimethylamino)-1-[5-methoxy-6-[[4-[(2-propan-2-ylsulfonylphenyl)amino]-5h-pyrrolo[3,2-d]pyrimidin-2-yl]amino]-2,3-dihydroindol-1-yl]ethanone | Human | 13483 | |
| ALK | ALK | TK | 7jy4 | A | | 1-{(1s,2s)-1-(2,4-difluorophenyl)-2-[2-(3-methyl-1h-pyrazol-5-yl)-4-(trifluoromethyl)phenoxy]cyclopropyl}methanamine | Human | 13240 | |
| ALK | ALK | TK | 7jyr | A | A | 4-{[(1r,2r)-2-(2,4-difluorophenyl)cyclopropyl]oxy}-3-(5-methyl-1h-pyrazol-3-yl)benzonitrile | Human | 13243 | |
| ALK | ALK | TK | 7jyr | A | B | 4-{[(1r,2r)-2-(2,4-difluorophenyl)cyclopropyl]oxy}-3-(5-methyl-1h-pyrazol-3-yl)benzonitrile | Human | 13241 | |
| ALK | ALK | TK | 7jys | A | A | 3-(3-chlorophenyl)-5-methyl-1h-pyrazole | Human | 13244 | |
| ALK | ALK | TK | 7jys | A | B | 3-(3-chlorophenyl)-5-methyl-1h-pyrazole | Human | 13239 | |
| ALK | ALK | TK | 7jyt | A | A | 3-(3-methyl-1h-pyrazol-5-yl)pyridine | Human | 13238 | |
| ALK | ALK | TK | 7jyt | A | B | 3-(3-methyl-1h-pyrazol-5-yl)pyridine | Human | 13242 | |
| ALK | ALK | TK | 7r7k | A | | 4-(6-amino-5-{(1r)-1-[5-fluoro-2-(2h-1,2,3-triazol-2-yl)phenyl]ethoxy}pyridin-3-yl)-2,3-dihydro-1h-isoindol-1-one | Human | 14267 | |
| ALK | ALK | TK | 7r7r | A | | (2r)-2-[5-(6-amino-5-{(1r)-1-[2-(1,3-dihydro-2h-1,2,3-triazol-2-yl)-5-fluorophenyl]ethoxy}pyridin-3-yl)-4-methyl-1,3-thiazol-2-yl]propane-1,2-diol | Human | 14266 | |
| ALK | ALK | TK | 8arj | A | A | 3-(dimethylamino)-1-[3-[4-(4-methylpiperazin-1-yl)phenyl]-9~{h}-pyrido[2,3-b]indol-6-yl]prop-2-en-1-one | Human | 14366 | |
| ALK | ALK | TK | 8arj | A | B | 3-(dimethylamino)-1-[3-[4-(4-methylpiperazin-1-yl)phenyl]-9~{h}-pyrido[2,3-b]indol-6-yl]prop-2-en-1-one | Human | 14367 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 5luq | A | | - | Human | 9321 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 5luq | B | | - | Human | 9319 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 5w1r | A | | - | Human | 9320 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 5y3r | C | | - | Human | 9318 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 6zfp | A | | - | Human | 12926 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 6zh2 | A | | - | Human | 12927 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 6zh4 | A | | - | Human | 12930 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 6zh6 | A | | - | Human | 12929 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 6zh8 | A | | - | Human | 12925 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 6zha | A | | - | Human | 12931 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 6zhe | A | | - | Human | 12928 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 6zhe | F | | - | Human | 12932 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 7k0y | A | A | - | Human | 13213 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 7k0y | A | B | - | Human | 13214 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 7k10 | A | | - | Human | 13217 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 7k11 | A | | - | Human | 13208 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 7k17 | A | | - | Human | 13215 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 7k17 | B | | - | Human | 13212 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 7k19 | A | | - | Human | 13216 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 7k1b | A | | - | Human | 13218 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 7k1j | A | | - | Human | 13209 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 7k1k | A | | - | Human | 13211 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 7k1n | A | | - | Human | 13210 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 7lt3 | C | | adenosine-5'-diphosphate | Human | 13500 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 7lt3 | L | | adenosine-5'-diphosphate | Human | 13501 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 7nfc | A | | - | Human | 13852 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 7nfe | A | | - | Human | 13851 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 7otm | A | | 8-(dibenzo[b,d]thiophen-4-yl)-2-(morpholin-4-yl)-4h-chromen-4-one | Human | 14061 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 7otp | A | | phosphothiophosphoric acid-adenylate ester | Human | 14054 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 7otv | A | | (1s,6br,9as,11r,11br)-9a,11b-dimethyl-1-[(methyloxy)methyl]-3,6,9-trioxo-1,6,6b,7,8,9,9a,10,11,11b-decahydro-3h-furo[4,3,2-de]indeno[4,5-h][2]benzopyran-11-yl acetate | Human | 14063 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 7otw | A | | 7-methyl-2-[(7-methyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino]-9-(oxan-4-yl)purin-8-one | Human | 14056 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 7oty | A | | (~{s})-[2-chloranyl-4-fluoranyl-5-(7-morpholin-4-ylquinazolin-4-yl)phenyl]-(6-methoxypyridazin-3-yl)methanol | Human | 14057 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 7sgl | A | A | adenosine-5'-triphosphate | Human | 14059 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 7sgl | A | B | adenosine-5'-triphosphate | Human | 14062 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 7su3 | A | A | adenosine-5'-triphosphate | Human | 14058 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 7su3 | A | B | adenosine-5'-triphosphate | Human | 14053 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 7sud | A | A | adenosine-5'-triphosphate | Human | 14055 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 7sud | A | B | adenosine-5'-triphosphate | Human | 14060 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 7tyr | A | A | - | Human | 14322 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 7tyr | A | B | - | Human | 14321 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 7z87 | A | A | (~{s})-[2-chloranyl-4-fluoranyl-5-(7-morpholin-4-ylquinazolin-4-yl)phenyl]-(6-methoxypyridazin-3-yl)methanol | Human | 14592 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 7z87 | A | B | (~{s})-[2-chloranyl-4-fluoranyl-5-(7-morpholin-4-ylquinazolin-4-yl)phenyl]-(6-methoxypyridazin-3-yl)methanol | Human | 14593 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 7z88 | A | | (~{s})-[2-chloranyl-4-fluoranyl-5-(7-morpholin-4-ylquinazolin-4-yl)phenyl]-(6-methoxypyridazin-3-yl)methanol | Human | 14594 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 8bh3 | A | | - | Human | 14768 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 8bhv | A | | - | Human | 14769 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 8bhy | A | | - | Human | 14770 | |
| ANTXR1 (DNAPK) | PIKK | Atypical | 8ezb | C | | adenosine-5'-triphosphate | Human | 14798 | |
| ATM | PIKK | Atypical | 5np0 | A | | - | Human | 9267 | |
| ATM | PIKK | Atypical | 5np0 | B | | - | Human | 9266 | |
| ATM | PIKK | Atypical | 5np1 | A | | - | Human | 9268 | |
| ATM | PIKK | Atypical | 6k9k | A | | - | Human | 11897 | |
| ATM | PIKK | Atypical | 6k9l | A | | - | Human | 11896 | |
| ATM | PIKK | Atypical | 6k9l | B | | - | Human | 11895 | |
| ATM | PIKK | Atypical | 7ni4 | A | | 8-(1,3-dimethylpyrazol-4-yl)-1-(3-fluoranyl-5-methoxy-pyridin-4-yl)-7-methoxy-3-methyl-imidazo[4,5-c]quinolin-2-one | Human | 13864 | |
| ATM | PIKK | Atypical | 7ni5 | A | | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one | Human | 13863 | |
| ATM | PIKK | Atypical | 7ni6 | A | | phosphothiophosphoric acid-adenylate ester | Human | 13862 | |
| ATM | PIKK | Atypical | 7sic | A | | phosphoaminophosphonic acid-adenylate ester | Human | 14101 | |
| ATM | PIKK | Atypical | 7sid | A | | phosphoaminophosphonic acid-adenylate ester | Human | 14102 | |
| ATM | PIKK | Atypical | 8oxm | B | | phosphoaminophosphonic acid-adenylate ester | Human | 14992 | |
| ATM | PIKK | Atypical | 8oxo | B | | phosphoaminophosphonic acid-adenylate ester | Human | 14993 | |
| ATM | PIKK | Atypical | 8oxp | A | | phosphoaminophosphonic acid-adenylate ester | Human | 14991 | |
| ATM | PIKK | Atypical | 8oxq | A | | phosphoaminophosphonic acid-adenylate ester | Human | 14990 | |
| ATR | PIKK | Atypical | 5yz0 | A | | - | Human | 9523 | |
| ATR | PIKK | Atypical | 5yz0 | B | | - | Human | 9524 | |
| Aurka (AurA) | AUR | Other | 3d14 | A | A | 1-{5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-1,3-thiazol-2-yl}-3-[3-(trifluoromethyl)phenyl]urea | Mouse | 5781 | |
| Aurka (AurA) | AUR | Other | 3d14 | A | B | 1-{5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-1,3-thiazol-2-yl}-3-[3-(trifluoromethyl)phenyl]urea | Mouse | 5775 | |
| Aurka (AurA) | AUR | Other | 3d15 | A | A | 1-(3-chlorophenyl)-3-{5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-1,3-thiazol-2-yl}urea | Mouse | 5777 | |
| Aurka (AurA) | AUR | Other | 3d2i | A | | 1-(5-{2-[(1-methyl-1h-pyrazolo[4,3-d]pyrimidin-7-yl)amino]ethyl}-1,3-thiazol-2-yl)-3-[3-(trifluoromethyl)phenyl]urea | Mouse | 5782 | |
| Aurka (AurA) | AUR | Other | 3d2k | A | | (7-{[2-(2-{[(3-chlorophenyl)carbamoyl]amino}-1,3-thiazol-5-yl)ethyl]amino}-1h-pyrazolo[4,3-d]pyrimidin-1-yl)acetic acid | Mouse | 5776 | |
| Aurka (AurA) | AUR | Other | 3daj | A | | n-butyl-3-{[6-(9h-purin-6-ylamino)hexanoyl]amino}benzamide | Mouse | 5779 | |
| Aurka (AurA) | AUR | Other | 3dj5 | A | | 3-({3-[(6-amino-5-bromopyrimidin-4-yl)sulfanyl]propanoyl}amino)-4-methoxy-n-phenylbenzamide | Mouse | 5783 | |
| Aurka (AurA) | AUR | Other | 3dj6 | A | | 4-methoxy-n-phenyl-3-({3-[(1h-pyrrolo[2,3-b]pyridin-5-ylmethyl)sulfanyl]propanoyl}amino)benzamide | Mouse | 5778 | |
| Aurka (AurA) | AUR | Other | 3dj7 | A | A | 1-(5-{2-[(6-amino-5-bromopyrimidin-4-yl)amino]ethyl}-1,3-thiazol-2-yl)-3-[3-(trifluoromethyl)phenyl]urea | Mouse | 5780 | |
| AURKA (AurA) | Aur | Other | 1mq4 | A | | adenosine-5'-diphosphate | Human | 1977 | |
| AURKA (AurA) | Aur | Other | 1muo | A | | adenosine | Human | 2062 | |
| AURKA (AurA) | Aur | Other | 1ol5 | A | | adenosine-5'-diphosphate | Human | 2080 | |
| AURKA (AurA) | Aur | Other | 1ol6 | A | | adenosine-5'-triphosphate | Human | 2081 | |
| AURKA (AurA) | Aur | Other | 1ol7 | A | | adenosine-5'-diphosphate | Human | 2014 | |
| AURKA (AurA) | Aur | Other | 2bmc | A | | (3e)-n-(2,6-diethylphenyl)-3-{[4-(4-methylpiperazin-1-yl)benzoyl]imino}pyrrolo[3,4-c]pyrazole-5(3h)-carboxamide | Human | 2015 | |
| AURKA (AurA) | Aur | Other | 2bmc | B | | (3e)-n-(2,6-diethylphenyl)-3-{[4-(4-methylpiperazin-1-yl)benzoyl]imino}pyrrolo[3,4-c]pyrazole-5(3h)-carboxamide | Human | 2008 | |
| AURKA (AurA) | Aur | Other | 2bmc | C | | (3e)-n-(2,6-diethylphenyl)-3-{[4-(4-methylpiperazin-1-yl)benzoyl]imino}pyrrolo[3,4-c]pyrazole-5(3h)-carboxamide | Human | 2060 | |
| AURKA (AurA) | Aur | Other | 2bmc | D | | (3e)-n-(2,6-diethylphenyl)-3-{[4-(4-methylpiperazin-1-yl)benzoyl]imino}pyrrolo[3,4-c]pyrazole-5(3h)-carboxamide | Human | 1984 | |
| AURKA (AurA) | Aur | Other | 2bmc | E | | (3e)-n-(2,6-diethylphenyl)-3-{[4-(4-methylpiperazin-1-yl)benzoyl]imino}pyrrolo[3,4-c]pyrazole-5(3h)-carboxamide | Human | 2069 | |
| AURKA (AurA) | Aur | Other | 2bmc | F | | (3e)-n-(2,6-diethylphenyl)-3-{[4-(4-methylpiperazin-1-yl)benzoyl]imino}pyrrolo[3,4-c]pyrazole-5(3h)-carboxamide | Human | 1993 | |
| AURKA (AurA) | Aur | Other | 2c6d | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 2019 | |
| AURKA (AurA) | Aur | Other | 2c6d | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 1981 | |
| AURKA (AurA) | Aur | Other | 2c6e | A | | n-{5-[(7-{[(2s)-2-hydroxy-3-piperidin-1-ylpropyl]oxy}-6-methoxyquinazolin-4-yl)amino]pyrimidin-2-yl}benzamide | Human | 1989 | |
| AURKA (AurA) | Aur | Other | 2c6e | B | | n-{5-[(7-{[(2s)-2-hydroxy-3-piperidin-1-ylpropyl]oxy}-6-methoxyquinazolin-4-yl)amino]pyrimidin-2-yl}benzamide | Human | 2046 | |
| AURKA (AurA) | Aur | Other | 2dwb | A | | phosphoaminophosphonic acid-adenylate ester | Human | 2035 | |
| AURKA (AurA) | Aur | Other | 2j4z | A | | 4-(4-methylpiperazin-1-yl)-n-[5-(2-thienylacetyl)-1,5-dihydropyrrolo[3,4-c]pyrazol-3-yl]benzamide | Human | 2053 | |
| AURKA (AurA) | Aur | Other | 2j4z | B | | 4-(4-methylpiperazin-1-yl)-n-[5-(2-thienylacetyl)-1,5-dihydropyrrolo[3,4-c]pyrazol-3-yl]benzamide | Human | 1990 | |
| AURKA (AurA) | Aur | Other | 2j50 | A | | n-[(3e)-5-[(2r)-2-methoxy-2-phenylacetyl]pyrrolo[3,4-c]pyrazol-3(5h)-ylidene]-4-(4-methylpiperazin-1-yl)benzamide | Human | 2001 | |
| AURKA (AurA) | Aur | Other | 2j50 | B | | n-[(3e)-5-[(2r)-2-methoxy-2-phenylacetyl]pyrrolo[3,4-c]pyrazol-3(5h)-ylidene]-4-(4-methylpiperazin-1-yl)benzamide | Human | 2050 | |
| AURKA (AurA) | Aur | Other | 2np8 | A | | n-{3-[(4-{[3-(trifluoromethyl)phenyl]amino}pyrimidin-2-yl)amino]phenyl}cyclopropanecarboxamide | Human | 2075 | |
| AURKA (AurA) | Aur | Other | 2w1c | A | | 4-{[2-(4-{[(4-fluorophenyl)carbonyl]amino}-1h-pyrazol-3-yl)-1h-benzimidazol-6-yl]methyl}morpholin-4-ium | Human | 2027 | |
| AURKA (AurA) | Aur | Other | 2w1d | A | | 2-(1h-pyrazol-3-yl)-1h-benzimidazole | Human | 2011 | |
| AURKA (AurA) | Aur | Other | 2w1e | A | | 4-[(2-{4-[(phenylcarbamoyl)amino]-1h-pyrazol-3-yl}-1h-benzimidazol-5-yl)methyl]morpholin-4-ium | Human | 2038 | |
| AURKA (AurA) | Aur | Other | 2w1f | A | | n-[3-(1h-benzimidazol-2-yl)-1h-pyrazol-4-yl]benzamide | Human | 2055 | |
| AURKA (AurA) | Aur | Other | 2w1g | A | | 2-{4-[(cyclopropylcarbamoyl)amino]-1h-pyrazol-3-yl}-6-(morpholin-4-ium-4-ylmethyl)-1h-3,1-benzimidazol-3-ium | Human | 1962 | |
| AURKA (AurA) | Aur | Other | 2wqe | A | | adenosine-5'-diphosphate | Human | 2071 | |
| AURKA (AurA) | Aur | Other | 2wtv | A | A | 4-{[9-chloro-7-(2,6-difluorophenyl)-5h-pyrimido[5,4-d][2]benzazepin-2-yl]amino}benzoic acid | Human | 2056 | |
| AURKA (AurA) | Aur | Other | 2wtv | A | B | 4-{[9-chloro-7-(2,6-difluorophenyl)-5h-pyrimido[5,4-d][2]benzazepin-2-yl]amino}benzoic acid | Human | 1997 | |
| AURKA (AurA) | Aur | Other | 2wtv | B | A | 4-{[9-chloro-7-(2,6-difluorophenyl)-5h-pyrimido[5,4-d][2]benzazepin-2-yl]amino}benzoic acid | Human | 2037 | |
| AURKA (AurA) | Aur | Other | 2wtv | B | B | 4-{[9-chloro-7-(2,6-difluorophenyl)-5h-pyrimido[5,4-d][2]benzazepin-2-yl]amino}benzoic acid | Human | 2057 | |
| AURKA (AurA) | Aur | Other | 2wtv | C | A | 4-{[9-chloro-7-(2,6-difluorophenyl)-5h-pyrimido[5,4-d][2]benzazepin-2-yl]amino}benzoic acid | Human | 2017 | |
| AURKA (AurA) | Aur | Other | 2wtv | C | B | 4-{[9-chloro-7-(2,6-difluorophenyl)-5h-pyrimido[5,4-d][2]benzazepin-2-yl]amino}benzoic acid | Human | 2016 | |
| AURKA (AurA) | Aur | Other | 2wtv | D | A | 4-{[9-chloro-7-(2,6-difluorophenyl)-5h-pyrimido[5,4-d][2]benzazepin-2-yl]amino}benzoic acid | Human | 2078 | |
| AURKA (AurA) | Aur | Other | 2wtv | D | B | 4-{[9-chloro-7-(2,6-difluorophenyl)-5h-pyrimido[5,4-d][2]benzazepin-2-yl]amino}benzoic acid | Human | 2076 | |
| AURKA (AurA) | Aur | Other | 2wtw | A | | 4-{[9-chloro-7-(2,6-difluorophenyl)-5h-pyrimido[5,4-d][2]benzazepin-2-yl]amino}benzoic acid | Human | 1956 | |
| AURKA (AurA) | Aur | Other | 2x6d | A | A | 6-bromo-7-[4-(4-chlorobenzyl)piperazin-1-yl]-2-[4-(morpholin-4-ylmethyl)phenyl]-3h-imidazo[4,5-b]pyridine | Human | 1978 | |
| AURKA (AurA) | Aur | Other | 2x6d | A | B | 6-bromo-7-[4-(4-chlorobenzyl)piperazin-1-yl]-2-[4-(morpholin-4-ylmethyl)phenyl]-3h-imidazo[4,5-b]pyridine | Human | 1975 | |
| AURKA (AurA) | Aur | Other | 2x6e | A | | 6-bromo-7-{4-[(5-methylisoxazol-3-yl)methyl]piperazin-1-yl}-2-[4-(4-methylpiperazin-1-yl)phenyl]-1h-imidazo[4,5-b]pyridine | Human | 2079 | |
| AURKA (AurA) | Aur | Other | 2x81 | A | | 4-{[9-chloro-7-(2,6-difluorophenyl)-5h-pyrimido[5,4-d][2]benzazepin-2-yl]amino}benzoic acid | Human | 1966 | |
| AURKA (AurA) | Aur | Other | 2xne | A | | 3-chloro-n-(4-morpholin-4-ylphenyl)-6-pyridin-3-ylimidazo[1,2-a]pyrazin-8-amine | Human | 7221 | |
| AURKA (AurA) | Aur | Other | 2xng | A | A | n-(3-{3-chloro-8-[(4-morpholin-4-ylphenyl)amino]imidazo[1,2-a]pyrazin-6-yl}benzyl)methanesulfonamide | Human | 1994 | |
| AURKA (AurA) | Aur | Other | 2xng | A | B | n-(3-{3-chloro-8-[(4-morpholin-4-ylphenyl)amino]imidazo[1,2-a]pyrazin-6-yl}benzyl)methanesulfonamide | Human | 2083 | |
| AURKA (AurA) | Aur | Other | 2xru | A | | 3-({[4-(4-methylpiperazin-1-yl)phenyl]carbonyl}amino)-n-[(1r)-1-phenylpropyl]-1h-thieno[3,2-c]pyrazole-5-carboxamide | Human | 1954 | |
| AURKA (AurA) | Aur | Other | 3coh | A | | 8-ethyl-3,10,10-trimethyl-4,5,6,8,10,12-hexahydropyrazolo[4',3':6,7]cyclohepta[1,2-b]pyrrolo[2,3-f]indol-9(1h)-one | Human | 1963 | |
| AURKA (AurA) | Aur | Other | 3coh | B | | 8-ethyl-3,10,10-trimethyl-4,5,6,8,10,12-hexahydropyrazolo[4',3':6,7]cyclohepta[1,2-b]pyrrolo[2,3-f]indol-9(1h)-one | Human | 2024 | |
| AURKA (AurA) | Aur | Other | 3e5a | A | | cyclopropanecarboxylic acid {4-[4-(4-methyl-piperazin-1-yl)-6-(5-methyl-2h-pyrazol-3-ylamino)-pyrimidin-2-ylsulfanyl]-phenyl}-amide | Human | 2006 | |
| AURKA (AurA) | Aur | Other | 3efw | A | | 1-[3-methyl-4-({3-[2-(methylamino)pyrimidin-4-yl]pyridin-2-yl}oxy)phenyl]-3-[3-(trifluoromethyl)phenyl]urea | Human | 2010 | |
| AURKA (AurA) | Aur | Other | 3efw | B | | 1-[3-methyl-4-({3-[2-(methylamino)pyrimidin-4-yl]pyridin-2-yl}oxy)phenyl]-3-[3-(trifluoromethyl)phenyl]urea | Human | 2074 | |
| AURKA (AurA) | Aur | Other | 3fdn | A | | n-[3-(acetylamino)phenyl]-5-{(2e)-2-[(4-methoxyphenyl)methylidene]hydrazino}-3-methyl-1h-pyrazole-4-carboxamide | Human | 1973 | |
| AURKA (AurA) | Aur | Other | 3h0y | A | | 2-chloro-n-[4-({5-fluoro-2-[(4-hydroxyphenyl)amino]pyrimidin-4-yl}amino)phenyl]benzamide | Human | 1965 | |
| AURKA (AurA) | Aur | Other | 3h0z | A | | 4-{[2-({4-[2-(4-acetylpiperazin-1-yl)-2-oxoethyl]phenyl}amino)-5-fluoropyrimidin-4-yl]amino}-n-(2-chlorophenyl)benzamide | Human | 1970 | |
| AURKA (AurA) | Aur | Other | 3h0z | B | | 4-{[2-({4-[2-(4-acetylpiperazin-1-yl)-2-oxoethyl]phenyl}amino)-5-fluoropyrimidin-4-yl]amino}-n-(2-chlorophenyl)benzamide | Human | 1986 | |
| AURKA (AurA) | Aur | Other | 3h0z | C | | 4-{[2-({4-[2-(4-acetylpiperazin-1-yl)-2-oxoethyl]phenyl}amino)-5-fluoropyrimidin-4-yl]amino}-n-(2-chlorophenyl)benzamide | Human | 2063 | |
| AURKA (AurA) | Aur | Other | 3h10 | A | | 9-chloro-7-(2,6-difluorophenyl)-n-{4-[(4-methylpiperazin-1-yl)carbonyl]phenyl}-5h-pyrimido[5,4-d][2]benzazepin-2-amine | Human | 2009 | |
| AURKA (AurA) | Aur | Other | 3h10 | B | | 9-chloro-7-(2,6-difluorophenyl)-n-{4-[(4-methylpiperazin-1-yl)carbonyl]phenyl}-5h-pyrimido[5,4-d][2]benzazepin-2-amine | Human | 1988 | |
| AURKA (AurA) | Aur | Other | 3h10 | D | | 9-chloro-7-(2,6-difluorophenyl)-n-{4-[(4-methylpiperazin-1-yl)carbonyl]phenyl}-5h-pyrimido[5,4-d][2]benzazepin-2-amine | Human | 2059 | |
| AURKA (AurA) | Aur | Other | 3ha6 | A | | n~2~-(3,4-dimethoxyphenyl)-n~4~-[2-(2-fluorophenyl)ethyl]-n~6~-quinolin-6-yl-1,3,5-triazine-2,4,6-triamine | Human | 2048 | |
| AURKA (AurA) | Aur | Other | 3k5u | A | | 2-[(5,6-diphenylfuro[2,3-d]pyrimidin-4-yl)amino]ethanol | Human | 2031 | |
| AURKA (AurA) | Aur | Other | 3lau | A | | n-[6-(4-hydroxyphenyl)-1h-indazol-3-yl]butanamide | Human | 1971 | |
| AURKA (AurA) | Aur | Other | 3m11 | A | | 1-(4-{2-[(5,6-diphenylfuro[2,3-d]pyrimidin-4-yl)amino]ethyl}phenyl)-3-phenylurea | Human | 2036 | |
| AURKA (AurA) | Aur | Other | 3myg | A | | 2-{ethyl[(5-{[6-methyl-3-(1h-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino}isothiazol-3-yl)methyl]amino}-2-methylpropan-1-ol | Human | 2065 | |
| AURKA (AurA) | Aur | Other | 3nrm | A | | n-(3-methylisothiazol-5-yl)-3-(1h-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine | Human | 2052 | |
| AURKA (AurA) | Aur | Other | 3o50 | A | | n-{3-methyl-4-[(3-pyrimidin-4-ylpyridin-2-yl)oxy]phenyl}-3-(trifluoromethyl)benzamide | Human | 1958 | |
| AURKA (AurA) | Aur | Other | 3o50 | B | | n-{3-methyl-4-[(3-pyrimidin-4-ylpyridin-2-yl)oxy]phenyl}-3-(trifluoromethyl)benzamide | Human | 2067 | |
| AURKA (AurA) | Aur | Other | 3o51 | A | | n-[4-({3-[5-fluoro-2-(methylideneamino)pyrimidin-4-yl]pyridin-2-yl}oxy)phenyl]-2-(phenylamino)benzamide | Human | 1974 | |
| AURKA (AurA) | Aur | Other | 3p9j | A | | 4-[(5-methyl-1h-pyrazol-3-yl)amino]-2-phenylphthalazin-1(2h)-one | Human | 2003 | |
| AURKA (AurA) | Aur | Other | 3qbn | A | | 5-chloro-n~4~-cyclopropyl-n~2~-[4-(2-methoxyethoxy)phenyl]pyrimidine-2,4-diamine | Human | 2032 | |
| AURKA (AurA) | Aur | Other | 3r21 | A | A | n-(2-aminoethyl)-n-{5-[(1-cycloheptyl-1h-pyrazolo[3,4-d]pyrimidin-6-yl)amino]pyridin-2-yl}methanesulfonamide | Human | 1991 | |
| AURKA (AurA) | Aur | Other | 3r21 | A | B | n-(2-aminoethyl)-n-{5-[(1-cycloheptyl-1h-pyrazolo[3,4-d]pyrimidin-6-yl)amino]pyridin-2-yl}methanesulfonamide | Human | 2033 | |
| AURKA (AurA) | Aur | Other | 3r22 | A | | n-{5-[(1-cycloheptyl-1h-pyrazolo[3,4-d]pyrimidin-6-yl)amino]pyridin-2-yl}methanesulfonamide | Human | 2034 | |
| AURKA (AurA) | Aur | Other | 3unz | A | | 4-({4-[(2-fluorophenyl)amino]pyrimidin-2-yl}amino)benzoic acid | Human | 1972 | |
| AURKA (AurA) | Aur | Other | 3unz | B | | 4-({4-[(2-fluorophenyl)amino]pyrimidin-2-yl}amino)benzoic acid | Human | 2049 | |
| AURKA (AurA) | Aur | Other | 3uo4 | A | | 4-{[4-(biphenyl-2-ylamino)pyrimidin-2-yl]amino}benzoic acid | Human | 1976 | |
| AURKA (AurA) | Aur | Other | 3uo5 | A | | 4-{[4-(phenylamino)pyrimidin-2-yl]amino}benzoic acid | Human | 2045 | |
| AURKA (AurA) | Aur | Other | 3uo6 | A | | 4-({4-[(2-chlorophenyl)amino]pyrimidin-2-yl}amino)benzoic acid | Human | 1985 | |
| AURKA (AurA) | Aur | Other | 3uo6 | B | | 4-({4-[(2-chlorophenyl)amino]pyrimidin-2-yl}amino)benzoic acid | Human | 1960 | |
| AURKA (AurA) | Aur | Other | 3uod | A | | 4-[(4-{[2-(trifluoromethyl)phenyl]amino}pyrimidin-2-yl)amino]benzoic acid | Human | 1980 | |
| AURKA (AurA) | Aur | Other | 3uoh | A | | 4-({4-[(2-bromophenyl)amino]pyrimidin-2-yl}amino)benzoic acid | Human | 2077 | |
| AURKA (AurA) | Aur | Other | 3uoh | B | | 4-({4-[(2-bromophenyl)amino]pyrimidin-2-yl}amino)benzoic acid | Human | 2000 | |
| AURKA (AurA) | Aur | Other | 3uoj | A | | 4-({4-[(2-cyanophenyl)amino]pyrimidin-2-yl}amino)benzoic acid | Human | 2042 | |
| AURKA (AurA) | Aur | Other | 3uoj | B | | 4-({4-[(2-cyanophenyl)amino]pyrimidin-2-yl}amino)benzoic acid | Human | 1979 | |
| AURKA (AurA) | Aur | Other | 3uok | A | | 4-({4-[(2-chlorophenyl)amino]-5-fluoropyrimidin-2-yl}amino)benzoic acid | Human | 2054 | |
| AURKA (AurA) | Aur | Other | 3uok | B | | 4-({4-[(2-chlorophenyl)amino]-5-fluoropyrimidin-2-yl}amino)benzoic acid | Human | 2047 | |
| AURKA (AurA) | Aur | Other | 3uol | A | | n~4~-(2-chlorophenyl)-n~2~-[4-(1h-tetrazol-5-yl)phenyl]pyrimidine-2,4-diamine | Human | 2004 | |
| AURKA (AurA) | Aur | Other | 3uol | B | | n~4~-(2-chlorophenyl)-n~2~-[4-(1h-tetrazol-5-yl)phenyl]pyrimidine-2,4-diamine | Human | 2051 | |
| AURKA (AurA) | Aur | Other | 3up2 | A | | 4-[(4-{[2-(trifluoromethoxy)phenyl]amino}pyrimidin-2-yl)amino]benzoic acid | Human | 2005 | |
| AURKA (AurA) | Aur | Other | 3up7 | A | | 2-({2-[(4-carboxyphenyl)amino]pyrimidin-4-yl}amino)benzoic acid | Human | 2025 | |
| AURKA (AurA) | Aur | Other | 3vap | A | | 3-(1-{2-[(3-fluoropyridinium-4-yl)amino]-2-oxoethyl}-1h-pyrazol-4-yl)-6-methyl-8-[(3-{[(1r,3r)-3-methylpiperidinium-1-yl]methyl}-1,2-thiazol-5-yl)amino]imidazo[1,2-a]pyrazin-1-ium | Human | 2029 | |
| AURKA (AurA) | Aur | Other | 3w10 | A | | 1-(3-methoxyphenyl)-n-(5-methyl-1h-pyrazol-3-yl)isoquinolin-3-amine | Human | 2068 | |
| AURKA (AurA) | Aur | Other | 3w16 | A | | 4-[(5-methyl-1h-pyrazol-3-yl)amino]-2-phenylphthalazin-1(2h)-one | Human | 2012 | |
| AURKA (AurA) | Aur | Other | 3w18 | A | | 2-{3-[3-(1h-benzimidazol-2-yl)-1h-indazol-6-yl]-1h-pyrazol-5-yl}-n-(3-fluorophenyl)acetamide | Human | 1961 | |
| AURKA (AurA) | Aur | Other | 3w18 | B | | 2-{3-[3-(1h-benzimidazol-2-yl)-1h-indazol-6-yl]-1h-pyrazol-5-yl}-n-(3-fluorophenyl)acetamide | Human | 1967 | |
| AURKA (AurA) | Aur | Other | 3w2c | A | | 2-{4-[3-(1h-benzimidazol-2-yl)-1h-indazol-6-yl]-1h-pyrazol-1-yl}-n-(3-methylbutyl)acetamide | Human | 2066 | |
| AURKA (AurA) | Aur | Other | 3w2c | C | | 2-{4-[3-(1h-benzimidazol-2-yl)-1h-indazol-6-yl]-1h-pyrazol-1-yl}-n-(3-methylbutyl)acetamide | Human | 2021 | |
| AURKA (AurA) | Aur | Other | 3w2c | E | | 2-{4-[3-(1h-benzimidazol-2-yl)-1h-indazol-6-yl]-1h-pyrazol-1-yl}-n-(3-methylbutyl)acetamide | Human | 1953 | |
| AURKA (AurA) | Aur | Other | 3w2c | G | | 2-{4-[3-(1h-benzimidazol-2-yl)-1h-indazol-6-yl]-1h-pyrazol-1-yl}-n-(3-methylbutyl)acetamide | Human | 2026 | |
| AURKA (AurA) | Aur | Other | 4b0g | A | A | 6-bromo-2-(1-methyl-1h-imidazol-5-yl)-7-{4-[(5-methyl-1,2-oxazol-3-yl)methyl]piperazin-1-yl}-1h-imidazo[4,5-b]pyridine | Human | 2082 | |
| AURKA (AurA) | Aur | Other | 4b0g | A | B | 6-bromo-2-(1-methyl-1h-imidazol-5-yl)-7-{4-[(5-methyl-1,2-oxazol-3-yl)methyl]piperazin-1-yl}-1h-imidazo[4,5-b]pyridine | Human | 2070 | |
| AURKA (AurA) | Aur | Other | 4bn1 | A | A | adenosine-5'-diphosphate | Human | 1955 | |
| AURKA (AurA) | Aur | Other | 4bn1 | A | B | adenosine-5'-diphosphate | Human | 1983 | |
| AURKA (AurA) | Aur | Other | 4byi | A | | (s)-n-((1-(6-chloro-2-(1,3-dimethyl-1h-pyrazol-4-yl)-3h-imidazo[4,5-b]pyridin-7-yl)pyrrolidin-3-yl)methyl)acetamide | Human | 1992 | |
| AURKA (AurA) | Aur | Other | 4byj | A | | (s)-n-(1-(6-chloro-2-(1,3-dimethyl-1h-pyrazol-4-yl)-3h-imidazo[4,5-b]pyridin-7-yl)pyrrolidin-3-yl)acetamide | Human | 1969 | |
| AURKA (AurA) | Aur | Other | 4c3p | A | | phosphomethylphosphonic acid adenylate ester | Human | 2018 | |
| AURKA (AurA) | Aur | Other | 4c3p | D | | phosphomethylphosphonic acid adenylate ester | Human | 2030 | |
| AURKA (AurA) | Aur | Other | 4c3r | A | | phosphomethylphosphonic acid adenylate ester | Human | 2058 | |
| AURKA (AurA) | Aur | Other | 4ceg | A | | adenosine-5'-diphosphate | Human | 2073 | |
| AURKA (AurA) | Aur | Other | 4dea | A | | 4,4'-(pyrimidine-2,4-diyldiimino)dibenzoic acid | Human | 2064 | |
| AURKA (AurA) | Aur | Other | 4deb | A | | 4-[(4-{[3-(trifluoromethyl)phenyl]amino}pyrimidin-2-yl)amino]benzamide | Human | 1996 | |
| AURKA (AurA) | Aur | Other | 4ded | A | | 2-({2-[(4-carbamoylphenyl)amino]pyrimidin-4-yl}amino)benzamide | Human | 2043 | |
| AURKA (AurA) | Aur | Other | 4dee | A | | adenosine-5'-diphosphate | Human | 1952 | |
| AURKA (AurA) | Aur | Other | 4dhf | A | | 7-cyclopentyl-2-({1-methyl-5-[(4-methylpiperazin-1-yl)carbonyl]-1h-pyrrol-3-yl}amino)-7h-pyrrolo[2,3-d]pyrimidine-6-carboxamide | Human | 1964 | |
| AURKA (AurA) | Aur | Other | 4dhf | B | | 7-cyclopentyl-2-({1-methyl-5-[(4-methylpiperazin-1-yl)carbonyl]-1h-pyrrol-3-yl}amino)-7h-pyrrolo[2,3-d]pyrimidine-6-carboxamide | Human | 1982 | |
| AURKA (AurA) | Aur | Other | 4j8m | A | | 1-[4-[[4-[(5-cyclopentyl-1h-pyrazol-3-yl)amino]pyrimidin-2-yl]amino]phenyl]-3-[3-(trifluoromethyl)phenyl]urea | Human | 2020 | |
| AURKA (AurA) | Aur | Other | 4j8n | A | | - | Human | 2028 | |
| AURKA (AurA) | Aur | Other | 4j8n | B | | - | Human | 2061 | |
| AURKA (AurA) | Aur | Other | 4j8n | C | | - | Human | 2007 | |
| AURKA (AurA) | Aur | Other | 4j8n | D | | - | Human | 1995 | |
| AURKA (AurA) | Aur | Other | 4jai | A | | n-{4-[(6-oxo-5,6-dihydrobenzo[c][1,8]naphthyridin-1-yl)amino]phenyl}benzamide | Human | 1999 | |
| AURKA (AurA) | Aur | Other | 4jaj | A | | benzo[c][1,8]naphthyridin-6(5h)-one | Human | 2040 | |
| AURKA (AurA) | Aur | Other | 4jbo | A | | 1-(4-{2-[(6-{4-[2-(dimethylamino)ethoxy]phenyl}furo[2,3-d]pyrimidin-4-yl)amino]ethyl}phenyl)-3-phenylurea | Human | 2072 | |
| AURKA (AurA) | Aur | Other | 4jbp | A | | 1-(4-{2-[(6-{4-[2-(4-hydroxypiperidin-1-yl)ethoxy]phenyl}furo[2,3-d]pyrimidin-4-yl)amino]ethyl}phenyl)-3-phenylurea | Human | 2041 | |
| AURKA (AurA) | Aur | Other | 4jbq | A | | cyclopropanecarboxylic acid {4-[4-(4-methyl-piperazin-1-yl)-6-(5-methyl-2h-pyrazol-3-ylamino)-pyrimidin-2-ylsulfanyl]-phenyl}-amide | Human | 1957 | |
| AURKA (AurA) | Aur | Other | 4o0s | A | | adenosine | Human | 2039 | |
| AURKA (AurA) | Aur | Other | 4o0u | A | | adenosine | Human | 2022 | |
| AURKA (AurA) | Aur | Other | 4o0w | A | | adenosine | Human | 1959 | |
| AURKA (AurA) | Aur | Other | 4prj | A | | n-[1-(3-cyanobenzyl)-1h-pyrazol-4-yl]-6-(1h-pyrazol-4-yl)-1h-indazole-3-carboxamide | Human | 2023 | |
| AURKA (AurA) | Aur | Other | 4uyn | A | | ethyl (9s)-9-[5-(1h-benzimidazol-2-ylsulfanyl)furan-2-yl]-8-hydroxy-5,6,7,9-tetrahydro-2h-pyrrolo[3,4-b]quinoline-3-carboxylate | Human | 2002 | |
| AURKA (AurA) | Aur | Other | 4uzd | A | | ethyl (9s)-9-[3-(1h-benzimidazol-2-yloxy)phenyl]-8-oxo-4,5,6,7,8,9-hexahydro-2h-pyrrolo[3,4-b]quinoline-3-carboxylate | Human | 2013 | |
| AURKA (AurA) | Aur | Other | 4uzd | B | | ethyl (9s)-9-[3-(1h-benzimidazol-2-yloxy)phenyl]-8-oxo-4,5,6,7,8,9-hexahydro-2h-pyrrolo[3,4-b]quinoline-3-carboxylate | Human | 1968 | |
| AURKA (AurA) | Aur | Other | 4uzh | A | | (4s)-4-(2-fluorophenyl)-2,4,6,7,8,9-hexahydro-5h-pyrazolo[3,4-b][1,7]naphthyridin-5-one | Human | 1998 | |
| AURKA (AurA) | Aur | Other | 4zs0 | A | | 5-hydroxy-1'h-1,2'-bibenzimidazol-2(3h)-one | Human | 6801 | |
| AURKA (AurA) | Aur | Other | 4ztq | A | | (2z,5z)-2-[(4-ethylphenyl)imino]-3-(2-methoxyethyl)-5-(pyridin-4-ylmethylidene)-1,3-thiazolidin-4-one | Human | 6804 | |
| AURKA (AurA) | Aur | Other | 4ztr | A | | 6-({4-[(z)-{(2z)-2-[(4-ethylphenyl)imino]-3-methyl-4-oxo-1,3-thiazolidin-5-ylidene}methyl]pyridin-2-yl}amino)pyridine-3-carboxylic acid | Human | 6817 | |
| AURKA (AurA) | Aur | Other | 4zts | A | | (2z,5z)-2-[(4-ethylphenyl)imino]-3-methyl-5-[(2-{[4-(1h-tetrazol-5-yl)phenyl]amino}pyridin-4-yl)methylidene]-1,3-thiazolidin-4-one | Human | 6814 | |
| AURKA (AurA) | Aur | Other | 5aad | A | | 7-(1-benzyl-1h-pyrazol-4-yl)-6-chloro-2-(1,3-dimethyl-1h-pyrazol-4-yl)-3h-imidazo[4,5-b]pyridine | Human | 6011 | |
| AURKA (AurA) | Aur | Other | 5aae | A | | 3-((4-(6-chloro-2-(1,3-dimethyl-1h-pyrazol-4-yl)-3h-imidazo[4,5-b]pyridin-7-yl)-1h-pyrazol-1-yl)methyl)-5-methylisoxazole | Human | 6012 | |
| AURKA (AurA) | Aur | Other | 5aaf | A | | 3-((4-(6-chloro-2-(1,3-dimethyl-1h-pyrazol-4-yl)-3h-imidazo[4,5-b]pyridin-7-yl)-1h-pyrazol-1-yl)methyl)-n,n-dimethylbenzamide | Human | 6013 | |
| AURKA (AurA) | Aur | Other | 5aag | A | | [3-[[4-[6-chloranyl-2-(1,3-dimethylpyrazol-4-yl)-3h-imidazo[4,5-b]pyridin-7-yl]pyrazol-1-yl]methyl]phenyl]-(4-methylpiperazin-1-yl)methanone | Human | 6010 | |
| AURKA (AurA) | Aur | Other | 5dn3 | A | A | adenosine-5'-triphosphate | Human | 6802 | |
| AURKA (AurA) | Aur | Other | 5dn3 | A | B | adenosine-5'-triphosphate | Human | 6818 | |
| AURKA (AurA) | Aur | Other | 5dnr | A | A | adenosine-5'-triphosphate | Human | 6810 | |
| AURKA (AurA) | Aur | Other | 5dnr | A | B | adenosine-5'-triphosphate | Human | 6809 | |
| AURKA (AurA) | Aur | Other | 5dos | A | | adenosine-5'-triphosphate | Human | 6807 | |
| AURKA (AurA) | Aur | Other | 5dpv | A | A | 4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1h-1,2,4-triazol-3-yl}amino)benzenesulfonamide | Human | 6808 | |
| AURKA (AurA) | Aur | Other | 5dpv | A | B | 4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1h-1,2,4-triazol-3-yl}amino)benzenesulfonamide | Human | 6826 | |
| AURKA (AurA) | Aur | Other | 5dr2 | A | | adenosine-5'-triphosphate | Human | 6825 | |
| AURKA (AurA) | Aur | Other | 5dr6 | A | A | 4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1h-1,2,4-triazol-3-yl}amino)benzenesulfonamide | Human | 6811 | |
| AURKA (AurA) | Aur | Other | 5dr6 | A | B | 4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1h-1,2,4-triazol-3-yl}amino)benzenesulfonamide | Human | 6805 | |
| AURKA (AurA) | Aur | Other | 5dr9 | A | | 4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1h-1,2,4-triazol-3-yl}amino)benzenesulfonamide | Human | 6821 | |
| AURKA (AurA) | Aur | Other | 5drd | A | | adenosine-5'-triphosphate | Human | 6823 | |
| AURKA (AurA) | Aur | Other | 5dt0 | A | A | 4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1h-1,2,4-triazol-3-yl}amino)benzenesulfonamide | Human | 6806 | |
| AURKA (AurA) | Aur | Other | 5dt0 | A | B | 4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1h-1,2,4-triazol-3-yl}amino)benzenesulfonamide | Human | 6803 | |
| AURKA (AurA) | Aur | Other | 5dt3 | A | | adenosine-5'-triphosphate | Human | 6816 | |
| AURKA (AurA) | Aur | Other | 5dt4 | A | | adenosine-5'-triphosphate | Human | 6815 | |
| AURKA (AurA) | Aur | Other | 5ew9 | A | A | 4-(3-chloranyl-2-fluoranyl-phenoxy)-1-[[6-(1,3-thiazol-2-ylamino)pyridin-2-yl]methyl]cyclohexane-1-carboxylic acid | Human | 6359 | |
| AURKA (AurA) | Aur | Other | 5ew9 | A | B | 4-(3-chloranyl-2-fluoranyl-phenoxy)-1-[[6-(1,3-thiazol-2-ylamino)pyridin-2-yl]methyl]cyclohexane-1-carboxylic acid | Human | 6360 | |
| AURKA (AurA) | Aur | Other | 5g15 | A | A | phosphomethylphosphonic acid adenylate ester | Human | 9737 | |
| AURKA (AurA) | Aur | Other | 5g15 | A | B | phosphomethylphosphonic acid adenylate ester | Human | 9739 | |
| AURKA (AurA) | Aur | Other | 5g1x | A | A | adenosine-5'-diphosphate | Human | 7267 | |
| AURKA (AurA) | Aur | Other | 5g1x | A | B | adenosine-5'-diphosphate | Human | 7266 | |
| AURKA (AurA) | Aur | Other | 5l8j | A | A | adenosine-5'-diphosphate | Human | 6820 | |
| AURKA (AurA) | Aur | Other | 5l8j | A | B | adenosine-5'-diphosphate | Human | 6812 | |
| AURKA (AurA) | Aur | Other | 5l8k | A | A | adenosine-5'-diphosphate | Human | 6819 | |
| AURKA (AurA) | Aur | Other | 5l8k | A | B | adenosine-5'-diphosphate | Human | 6813 | |
| AURKA (AurA) | Aur | Other | 5l8l | A | A | adenosine-5'-diphosphate | Human | 6822 | |
| AURKA (AurA) | Aur | Other | 5l8l | A | B | adenosine-5'-diphosphate | Human | 6824 | |
| AURKA (AurA) | Aur | Other | 5lxm | A | A | adenosine-5'-diphosphate | Human | 7142 | |
| AURKA (AurA) | Aur | Other | 5lxm | A | B | adenosine-5'-diphosphate | Human | 7141 | |
| AURKA (AurA) | Aur | Other | 5obj | A | | adenosine-5'-triphosphate | Human | 8305 | |
| AURKA (AurA) | Aur | Other | 5obr | A | | 4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1h-1,2,4-triazol-3-yl}amino)benzenesulfonamide | Human | 8304 | |
| AURKA (AurA) | Aur | Other | 5odt | A | A | adenosine-5'-diphosphate | Human | 9738 | |
| AURKA (AurA) | Aur | Other | 5odt | A | B | adenosine-5'-diphosphate | Human | 9736 | |
| AURKA (AurA) | Aur | Other | 5one | A | A | 4-(propanoylamino)-~{n}-[4-[(5,8,11-trimethyl-6-oxidanylidene-pyrimido[4,5-b][1,4]benzodiazepin-2-yl)amino]phenyl]benzamide | Human | 8371 | |
| AURKA (AurA) | Aur | Other | 5one | A | B | 4-(propanoylamino)-~{n}-[4-[(5,8,11-trimethyl-6-oxidanylidene-pyrimido[4,5-b][1,4]benzodiazepin-2-yl)amino]phenyl]benzamide | Human | 8370 | |
| AURKA (AurA) | Aur | Other | 5orl | A | | adenosine-5'-diphosphate | Human | 8642 | |
| AURKA (AurA) | Aur | Other | 5orn | A | | adenosine-5'-diphosphate | Human | 8649 | |
| AURKA (AurA) | Aur | Other | 5oro | A | | adenosine-5'-diphosphate | Human | 8641 | |
| AURKA (AurA) | Aur | Other | 5orp | A | | adenosine-5'-diphosphate | Human | 8648 | |
| AURKA (AurA) | Aur | Other | 5orr | A | | adenosine-5'-diphosphate | Human | 8636 | |
| AURKA (AurA) | Aur | Other | 5ors | A | | adenosine-5'-diphosphate | Human | 8646 | |
| AURKA (AurA) | Aur | Other | 5ort | A | | adenosine-5'-diphosphate | Human | 8638 | |
| AURKA (AurA) | Aur | Other | 5orv | A | | adenosine-5'-diphosphate | Human | 8643 | |
| AURKA (AurA) | Aur | Other | 5orw | A | | adenosine-5'-diphosphate | Human | 8631 | |
| AURKA (AurA) | Aur | Other | 5orx | A | | adenosine-5'-diphosphate | Human | 8644 | |
| AURKA (AurA) | Aur | Other | 5ory | A | | adenosine-5'-diphosphate | Human | 8627 | |
| AURKA (AurA) | Aur | Other | 5orz | A | A | adenosine-5'-diphosphate | Human | 8639 | |
| AURKA (AurA) | Aur | Other | 5orz | A | B | adenosine-5'-diphosphate | Human | 8650 | |
| AURKA (AurA) | Aur | Other | 5os0 | A | | adenosine-5'-diphosphate | Human | 8632 | |
| AURKA (AurA) | Aur | Other | 5os1 | A | A | adenosine-5'-diphosphate | Human | 8628 | |
| AURKA (AurA) | Aur | Other | 5os1 | A | B | adenosine-5'-diphosphate | Human | 8630 | |
| AURKA (AurA) | Aur | Other | 5os2 | A | A | adenosine-5'-diphosphate | Human | 8635 | |
| AURKA (AurA) | Aur | Other | 5os2 | A | B | adenosine-5'-diphosphate | Human | 8633 | |
| AURKA (AurA) | Aur | Other | 5os3 | A | | adenosine-5'-diphosphate | Human | 8637 | |
| AURKA (AurA) | Aur | Other | 5os4 | A | | adenosine-5'-diphosphate | Human | 8652 | |
| AURKA (AurA) | Aur | Other | 5os5 | A | A | adenosine-5'-diphosphate | Human | 8647 | |
| AURKA (AurA) | Aur | Other | 5os5 | A | B | adenosine-5'-diphosphate | Human | 8629 | |
| AURKA (AurA) | Aur | Other | 5os6 | A | | adenosine-5'-diphosphate | Human | 8651 | |
| AURKA (AurA) | Aur | Other | 5osd | A | | adenosine-5'-diphosphate | Human | 8634 | |
| AURKA (AurA) | Aur | Other | 5ose | A | | adenosine-5'-diphosphate | Human | 8645 | |
| AURKA (AurA) | Aur | Other | 5osf | A | | adenosine-5'-diphosphate | Human | 8640 | |
| AURKA (AurA) | Aur | Other | 5zan | A | | 7-(4-methylpiperazin-1-yl)-n-(5-methyl-1h-pyrazol-3-yl)-2-[(e)-2-phenylethenyl]quinazolin-4-amine | Human | 10898 | |
| AURKA (AurA) | Aur | Other | 6c2r | A | A | (2r,4r)-1-[(3-chloro-2-fluorophenyl)methyl]-4-({3-fluoro-6-[(5-methyl-1h-pyrazol-3-yl)amino]pyridin-2-yl}methyl)-2-methylpiperidine-4-carboxylic acid | Human | 10864 | |
| AURKA (AurA) | Aur | Other | 6c2r | A | B | (2r,4r)-1-[(3-chloro-2-fluorophenyl)methyl]-4-({3-fluoro-6-[(5-methyl-1h-pyrazol-3-yl)amino]pyridin-2-yl}methyl)-2-methylpiperidine-4-carboxylic acid | Human | 10865 | |
| AURKA (AurA) | Aur | Other | 6c2t | A | A | (2s,4r)-1-[(3-chloro-2-fluorophenyl)methyl]-2-methyl-4-({3-[(1,3-thiazol-2-yl)amino]isoquinolin-1-yl}methyl)piperidine-4-carboxylic acid | Human | 10866 | |
| AURKA (AurA) | Aur | Other | 6c2t | A | B | (2s,4r)-1-[(3-chloro-2-fluorophenyl)methyl]-2-methyl-4-({3-[(1,3-thiazol-2-yl)amino]isoquinolin-1-yl}methyl)piperidine-4-carboxylic acid | Human | 10863 | |
| AURKA (AurA) | Aur | Other | 6c83 | A | | phosphomethylphosphonic acid adenylate ester | Human | 10934 | |
| AURKA (AurA) | Aur | Other | 6c83 | B | | phosphomethylphosphonic acid adenylate ester | Human | 10935 | |
| AURKA (AurA) | Aur | Other | 6cpe | A | A | - | Human | 10036 | |
| AURKA (AurA) | Aur | Other | 6cpe | A | B | - | Human | 10035 | |
| AURKA (AurA) | Aur | Other | 6cpf | A | | phosphomethylphosphonic acid adenylate ester | Human | 10033 | |
| AURKA (AurA) | Aur | Other | 6cpg | A | | 1-cyclopropyl-3-{3-[5-(morpholin-4-ylmethyl)-1h-benzimidazol-2-yl]-1h-pyrazol-4-yl}urea | Human | 10032 | |
| AURKA (AurA) | Aur | Other | 6cpg | D | | 1-cyclopropyl-3-{3-[5-(morpholin-4-ylmethyl)-1h-benzimidazol-2-yl]-1h-pyrazol-4-yl}urea | Human | 10034 | |
| AURKA (AurA) | Aur | Other | 6gra | A | | 1-[(2~{r},3~{s})-2-[[1,3-benzodioxol-5-ylmethyl(methyl)amino]methyl]-3-methyl-6-oxidanylidene-5-[(2~{s})-1-oxidanylpropan-2-yl]-3,4-dihydro-2~{h}-1,5-benzoxazocin-8-yl]-3-(4-methoxyphenyl)urea | Human | 11130 | |
| AURKA (AurA) | Aur | Other | 6hjj | A | A | ~{n}-[4-(4-azanyl-1-propan-2-yl-pyrazolo[3,4-d]pyrimidin-3-yl)-3-methyl-phenyl]-4-[4-fluoranyl-3-(trifluoromethyl)phenyl]-4-oxidanylidene-butanamide | Human | 10410 | |
| AURKA (AurA) | Aur | Other | 6hjj | A | B | ~{n}-[4-(4-azanyl-1-propan-2-yl-pyrazolo[3,4-d]pyrimidin-3-yl)-3-methyl-phenyl]-4-[4-fluoranyl-3-(trifluoromethyl)phenyl]-4-oxidanylidene-butanamide | Human | 10412 | |
| AURKA (AurA) | Aur | Other | 6hjk | A | | (~{e})-~{n}-[4-(4-azanyl-1-propan-2-yl-pyrazolo[3,4-d]pyrimidin-3-yl)phenyl]-4-[4-fluoranyl-3-(trifluoromethyl)phenyl]-4-oxidanylidene-but-2-enamide | Human | 10411 | |
| AURKA (AurA) | Aur | Other | 6i2u | A | | - | Human | 11652 | |
| AURKA (AurA) | Aur | Other | 6r49 | A | | adenosine-5'-diphosphate | Human | 11131 | |
| AURKA (AurA) | Aur | Other | 6r4a | A | | adenosine-5'-diphosphate | Human | 11134 | |
| AURKA (AurA) | Aur | Other | 6r4b | A | B | adenosine-5'-diphosphate | Human | 11133 | |
| AURKA (AurA) | Aur | Other | 6r4c | A | | adenosine-5'-diphosphate | Human | 11135 | |
| AURKA (AurA) | Aur | Other | 6r4d | A | | adenosine-5'-diphosphate | Human | 11132 | |
| AURKA (AurA) | Aur | Other | 6vpg | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 12659 | |
| AURKA (AurA) | Aur | Other | 6vpg | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 12667 | |
| AURKA (AurA) | Aur | Other | 6vph | A | A | dithiane diol | Human | 12666 | |
| AURKA (AurA) | Aur | Other | 6vph | A | B | dithiane diol | Human | 12655 | |
| AURKA (AurA) | Aur | Other | 6vpi | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 12656 | |
| AURKA (AurA) | Aur | Other | 6vpi | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 12669 | |
| AURKA (AurA) | Aur | Other | 6vpj | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 12657 | |
| AURKA (AurA) | Aur | Other | 6vpj | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 12654 | |
| AURKA (AurA) | Aur | Other | 6vpl | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 12662 | |
| AURKA (AurA) | Aur | Other | 6vpl | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 12670 | |
| AURKA (AurA) | Aur | Other | 6vpl | B | A | phosphoaminophosphonic acid-adenylate ester | Human | 12664 | |
| AURKA (AurA) | Aur | Other | 6vpl | B | B | phosphoaminophosphonic acid-adenylate ester | Human | 12668 | |
| AURKA (AurA) | Aur | Other | 6vpm | A | A | adenosine monophosphate | Human | 12661 | |
| AURKA (AurA) | Aur | Other | 6vpm | A | B | adenosine monophosphate | Human | 12658 | |
| AURKA (AurA) | Aur | Other | 6vpm | B | A | adenosine monophosphate | Human | 12660 | |
| AURKA (AurA) | Aur | Other | 6vpm | B | B | adenosine monophosphate | Human | 12663 | |
| AURKA (AurA) | Aur | Other | 6xka | A | | - | Human | 12665 | |
| AURKA (AurA) | Aur | Other | 6z4y | A | A | 6-(2-methoxyethoxy)-11-methyl-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-10-one | Human | 12306 | |
| AURKA (AurA) | Aur | Other | 6z4y | A | B | 6-(2-methoxyethoxy)-11-methyl-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-10-one | Human | 12307 | |
| AURKA (AurA) | Aur | Other | 7ayh | A | | 7-[2-[(4-methoxyphenyl)amino]pyrimidin-4-yl]-1,3,4,5-tetrahydro-1-benzazepin-2-one | Human | 13228 | |
| AURKA (AurA) | Aur | Other | 7ayi | A | | 7-(2-phenylazanylpyrimidin-4-yl)-1,3,4,5-tetrahydro-1-benzazepin-2-one | Human | 13229 | |
| AURKA (AurA) | Aur | Other | 7fic | A | A | 6-[(5-cyclopropyl-1~{h}-pyrazol-3-yl)amino]-2-[4-[(3-methyl-4-oxidanyl-phenyl)methyl]piperazin-1-yl]-~{n}-prop-2-ynyl-pyrimidine-4-carboxamide | Human | 14234 | |
| AURKA (AurA) | Aur | Other | 7fic | A | B | 6-[(5-cyclopropyl-1~{h}-pyrazol-3-yl)amino]-2-[4-[(3-methyl-4-oxidanyl-phenyl)methyl]piperazin-1-yl]-~{n}-prop-2-ynyl-pyrimidine-4-carboxamide | Human | 14233 | |
| AURKA (AurA) | Aur | Other | 7o2v | A | | 1-[[3,4-bis(fluoranyl)phenyl]methyl]-~{n}-[(1~{r})-2-[[(3~{e})-3-(1~{h}-imidazol-5-ylmethylidene)-2-oxidanylidene-1~{h}-indol-5-yl]amino]-2-oxidanylidene-1-phenyl-ethyl]-6-methyl-2-oxidanylidene-pyridine-3-carboxamide | Human | 13947 | |
| AURKA (AurA) | Aur | Other | 7ztl | A | A | adenosine-5'-diphosphate | Human | 14582 | |
| AURKA (AurA) | Aur | Other | 7ztl | A | B | adenosine-5'-diphosphate | Human | 14581 | |
| AURKA (AurA) | Aur | Other | 8c14 | A | A | adenosine-5'-diphosphate | Human | 15143 | |
| AURKA (AurA) | Aur | Other | 8c14 | A | B | adenosine-5'-diphosphate | Human | 15150 | |
| AURKA (AurA) | Aur | Other | 8c15 | A | A | adenosine-5'-diphosphate | Human | 15141 | |
| AURKA (AurA) | Aur | Other | 8c15 | A | B | adenosine-5'-diphosphate | Human | 15151 | |
| AURKA (AurA) | Aur | Other | 8c1d | A | A | adenosine-5'-diphosphate | Human | 15152 | |
| AURKA (AurA) | Aur | Other | 8c1d | A | B | adenosine-5'-diphosphate | Human | 15138 | |
| AURKA (AurA) | Aur | Other | 8c1e | A | | adenosine-5'-triphosphate | Human | 15145 | |
| AURKA (AurA) | Aur | Other | 8c1f | A | A | adenosine-5'-diphosphate | Human | 15140 | |
| AURKA (AurA) | Aur | Other | 8c1f | A | B | adenosine-5'-diphosphate | Human | 15149 | |
| AURKA (AurA) | Aur | Other | 8c1g | A | | adenosine-5'-diphosphate | Human | 15148 | |
| AURKA (AurA) | Aur | Other | 8c1h | A | A | adenosine-5'-diphosphate | Human | 15147 | |
| AURKA (AurA) | Aur | Other | 8c1h | A | B | adenosine-5'-diphosphate | Human | 15142 | |
| AURKA (AurA) | Aur | Other | 8c1i | A | A | adenosine-5'-diphosphate | Human | 15144 | |
| AURKA (AurA) | Aur | Other | 8c1i | A | B | adenosine-5'-diphosphate | Human | 15139 | |
| AURKA (AurA) | Aur | Other | 8c1k | A | | adenosine-5'-diphosphate | Human | 15146 | |
| AURKA (AurA) | Aur | Other | 8c1m | A | | adenosine-5'-diphosphate | Human | 15137 | |
| AURKA (AurA) | Aur | Other | 8guw | A | | adenosine-5'-diphosphate | Human | 14753 | |
| AURKA (AurA) | Aur | Other | 8jf4 | A | | 2-[4-[4-[bis(oxidanylidene)-$l^5-sulfanyl]oxyphenyl]carbonylpiperazin-1-yl]-6-[(5-cyclopropyl-1h-pyrazol-3-yl)amino]-n-prop-2-ynyl-pyrimidine-4-carboxamide | Human | 15217 | |
| AURKA (AurA) | Aur | Other | 8jg8 | A | | 4-[5-[3-[bis(oxidanylidene)-$l^5-sulfanyl]oxyphenyl]-7h-pyrrolo[2,3-d]pyrimidin-4-yl]morpholine | Human | 15272 | |
| AURKA (AurA) | Aur | Other | 8jmx | A | | 5-(4-morpholin-4-yl-7h-pyrrolo[2,3-d]pyrimidin-5-yl)-2-oxidanyl-benzaldehyde | Human | 14864 | |
| AURKA (AurA) | Aur | Other | 8of5 | A | | adenosine-5'-diphosphate | Human | 15218 | |
| AURKA (AurA) | Aur | Other | 8pr7 | A | | adenosine-5'-diphosphate | Human | 15292 | |
| AURKA (AurA) | Aur | Other | 8sso | A | A | n-[(3e)-5-[(2r)-2-methoxy-2-phenylacetyl]pyrrolo[3,4-c]pyrazol-3(5h)-ylidene]-4-(4-methylpiperazin-1-yl)benzamide | Human | 14866 | |
| AURKA (AurA) | Aur | Other | 8sso | A | B | n-[(3e)-5-[(2r)-2-methoxy-2-phenylacetyl]pyrrolo[3,4-c]pyrazol-3(5h)-ylidene]-4-(4-methylpiperazin-1-yl)benzamide | Human | 14867 | |
| AURKA (AurA) | Aur | Other | 8sso | A | C | n-[(3e)-5-[(2r)-2-methoxy-2-phenylacetyl]pyrrolo[3,4-c]pyrazol-3(5h)-ylidene]-4-(4-methylpiperazin-1-yl)benzamide | Human | 14863 | |
| AURKA (AurA) | Aur | Other | 8ssp | A | A | n-[(3e)-5-[(2r)-2-methoxy-2-phenylacetyl]pyrrolo[3,4-c]pyrazol-3(5h)-ylidene]-4-(4-methylpiperazin-1-yl)benzamide | Human | 14868 | |
| AURKA (AurA) | Aur | Other | 8ssp | A | B | n-[(3e)-5-[(2r)-2-methoxy-2-phenylacetyl]pyrrolo[3,4-c]pyrazol-3(5h)-ylidene]-4-(4-methylpiperazin-1-yl)benzamide | Human | 14865 | |
| AURKB (AurB) | Aur | Other | 4af3 | A | | cyclopropanecarboxylic acid {4-[4-(4-methyl-piperazin-1-yl)-6-(5-methyl-2h-pyrazol-3-ylamino)-pyrimidin-2-ylsulfanyl]-phenyl}-amide | Human | 407 | |
| AURKC (AurC) | Aur | Other | 6gr8 | A | A | 1-[(2~{r},3~{s})-2-[[1,3-benzodioxol-5-ylmethyl(methyl)amino]methyl]-3-methyl-6-oxidanylidene-5-[(2~{s})-1-oxidanylpropan-2-yl]-3,4-dihydro-2~{h}-1,5-benzoxazocin-8-yl]-3-(4-methoxyphenyl)urea | Human | 11122 | |
| AURKC (AurC) | Aur | Other | 6gr8 | A | B | 1-[(2~{r},3~{s})-2-[[1,3-benzodioxol-5-ylmethyl(methyl)amino]methyl]-3-methyl-6-oxidanylidene-5-[(2~{s})-1-oxidanylpropan-2-yl]-3,4-dihydro-2~{h}-1,5-benzoxazocin-8-yl]-3-(4-methoxyphenyl)urea | Human | 11125 | |
| AURKC (AurC) | Aur | Other | 6gr9 | A | A | cyclopropanecarboxylic acid {4-[4-(4-methyl-piperazin-1-yl)-6-(5-methyl-2h-pyrazol-3-ylamino)-pyrimidin-2-ylsulfanyl]-phenyl}-amide | Human | 11123 | |
| AURKC (AurC) | Aur | Other | 6gr9 | A | B | cyclopropanecarboxylic acid {4-[4-(4-methyl-piperazin-1-yl)-6-(5-methyl-2h-pyrazol-3-ylamino)-pyrimidin-2-ylsulfanyl]-phenyl}-amide | Human | 11124 | |
| AXL | Axl | TK | 5u6b | A | | (10r)-7-amino-11-chloro-12-fluoro-1-(2-hydroxyethyl)-3,10,16-trimethyl-16,17-dihydro-1h-8,4-(azeno)pyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecin-15(10h)-one | Human | 8258 | |
| AXL | Axl | TK | 5u6b | B | | (10r)-7-amino-11-chloro-12-fluoro-1-(2-hydroxyethyl)-3,10,16-trimethyl-16,17-dihydro-1h-8,4-(azeno)pyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecin-15(10h)-one | Human | 8260 | |
| AXL | Axl | TK | 5u6b | C | | (10r)-7-amino-11-chloro-12-fluoro-1-(2-hydroxyethyl)-3,10,16-trimethyl-16,17-dihydro-1h-8,4-(azeno)pyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecin-15(10h)-one | Human | 8257 | |
| AXL | Axl | TK | 5u6b | D | | (10r)-7-amino-11-chloro-12-fluoro-1-(2-hydroxyethyl)-3,10,16-trimethyl-16,17-dihydro-1h-8,4-(azeno)pyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecin-15(10h)-one | Human | 8259 | |
| BMP2K (BIKE) | NAK | Other | 4w9w | A | A | 5-(3-fluorophenyl)-n-[(3s)-3-piperidyl]-3-ureido-thiophene-2-carboxamide | Human | 3274 | |
| BMP2K (BIKE) | NAK | Other | 4w9w | A | B | 5-(3-fluorophenyl)-n-[(3s)-3-piperidyl]-3-ureido-thiophene-2-carboxamide | Human | 3272 | |
| BMP2K (BIKE) | NAK | Other | 4w9x | A | | baricitinib | Human | 3273 | |
| BMP2K (BIKE) | NAK | Other | 5i3o | A | | n-(6-{3-[(dimethylsulfamoyl)amino]phenyl}-1h-indazol-3-yl)cyclopropanecarboxamide | Human | 6437 | |
| BMP2K (BIKE) | NAK | Other | 5i3o | B | | n-(6-{3-[(dimethylsulfamoyl)amino]phenyl}-1h-indazol-3-yl)cyclopropanecarboxamide | Human | 6434 | |
| BMP2K (BIKE) | NAK | Other | 5i3r | A | | n-[6-(3-{[(cyclopropylmethyl)sulfonyl]amino}phenyl)-1h-indazol-3-yl]cyclopropanecarboxamide | Human | 6435 | |
| BMP2K (BIKE) | NAK | Other | 5i3r | B | | n-[6-(3-{[(cyclopropylmethyl)sulfonyl]amino}phenyl)-1h-indazol-3-yl]cyclopropanecarboxamide | Human | 6436 | |
| BMP2K (BIKE) | NAK | Other | 5ikw | A | | n-(6-{3-[(cyclopropylsulfonyl)amino]phenyl}-1h-indazol-3-yl)cyclopropanecarboxamide | Human | 6709 | |
| BMPR1B | STKR | TKL | 3mdy | A | A | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | 1502 | |
| BMPR1B | STKR | TKL | 3mdy | A | B | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | 1501 | |
| BMPR1B | STKR | TKL | 3mdy | C | A | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | 1503 | |
| BMPR1B | STKR | TKL | 3mdy | C | B | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | 1500 | |
| BMPR2 | STKR | TKL | 3g2f | A | A | adenosine-5'-diphosphate | Human | 6870 | |
| BMPR2 | STKR | TKL | 3g2f | A | B | adenosine-5'-diphosphate | Human | 6868 | |
| BMPR2 | STKR | TKL | 3g2f | B | A | adenosine-5'-diphosphate | Human | 6867 | |
| BMPR2 | STKR | TKL | 3g2f | B | B | adenosine-5'-diphosphate | Human | 6869 | |
| BMPR2 | STKR | TKL | 6unp | A | A | adenosine-5'-diphosphate | Human | 13795 | |
| BMPR2 | STKR | TKL | 6unp | A | B | adenosine-5'-diphosphate | Human | 13794 | |
| BMX | Tec | TK | 3sxr | A | | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 3482 | |
| BMX | Tec | TK | 3sxr | B | | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 3481 | |
| BMX | Tec | TK | 3sxs | A | | 1-tert-butyl-3-(4-chloro-phenyl)-1h-pyrazolo[3,4-d]pyrimidin-4-ylamine | Human | 3483 | |
| BMX | Tec | TK | 6i99 | A | | ~{n}-[2-methyl-5-[8-[4-(methylsulfonylamino)phenyl]-2-oxidanylidene-benzo[h][1,6]naphthyridin-1-yl]phenyl]-3-oxidanyl-propanamide | Human | 12348 | |
| BMX | Tec | TK | 6i99 | B | | ~{n}-[2-methyl-5-[8-[4-(methylsulfonylamino)phenyl]-2-oxidanylidene-benzo[h][1,6]naphthyridin-1-yl]phenyl]-3-oxidanyl-propanamide | Human | 12349 | |
| BMX | Tec | TK | 8x2a | A | A | 4-[(3s)-3-{[(2e)-but-2-enoyl]amino}piperidin-1-yl]-5-fluoro-2,3-dimethyl-1h-indole-7-carboxamide | Human | 15131 | |
| BMX | Tec | TK | 8x2a | A | B | 4-[(3s)-3-{[(2e)-but-2-enoyl]amino}piperidin-1-yl]-5-fluoro-2,3-dimethyl-1h-indole-7-carboxamide | Human | 15130 | |
| BRAF | RAF | TKL | 1uwh | A | | 4-{4-[({[4-chloro-3-(trifluoromethyl)phenyl]amino}carbonyl)amino]phenoxy}-n-methylpyridine-2-carboxamide | Human | 3127 | |
| BRAF | RAF | TKL | 1uwh | B | | 4-{4-[({[4-chloro-3-(trifluoromethyl)phenyl]amino}carbonyl)amino]phenoxy}-n-methylpyridine-2-carboxamide | Human | 3109 | |
| BRAF | RAF | TKL | 1uwj | A | | 4-{4-[({[4-chloro-3-(trifluoromethyl)phenyl]amino}carbonyl)amino]phenoxy}-n-methylpyridine-2-carboxamide | Human | 3135 | |
| BRAF | RAF | TKL | 1uwj | B | | 4-{4-[({[4-chloro-3-(trifluoromethyl)phenyl]amino}carbonyl)amino]phenoxy}-n-methylpyridine-2-carboxamide | Human | 3105 | |
| BRAF | RAF | TKL | 2fb8 | A | | (1z)-5-(2-{4-[2-(dimethylamino)ethoxy]phenyl}-5-pyridin-4-yl-1h-imidazol-4-yl)indan-1-one oxime | Human | 3062 | |
| BRAF | RAF | TKL | 2fb8 | B | | (1z)-5-(2-{4-[2-(dimethylamino)ethoxy]phenyl}-5-pyridin-4-yl-1h-imidazol-4-yl)indan-1-one oxime | Human | 3086 | |
| BRAF | RAF | TKL | 3c4c | A | | n-{3-[(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl}propane-1-sulfonamide | Human | 3115 | |
| BRAF | RAF | TKL | 3c4c | B | | n-{3-[(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl}propane-1-sulfonamide | Human | 3063 | |
| BRAF | RAF | TKL | 3d4q | A | | (1e)-5-(1-piperidin-4-yl-3-pyridin-4-yl-1h-pyrazol-4-yl)-2,3-dihydro-1h-inden-1-one oxime | Human | 3095 | |
| BRAF | RAF | TKL | 3d4q | B | | (1e)-5-(1-piperidin-4-yl-3-pyridin-4-yl-1h-pyrazol-4-yl)-2,3-dihydro-1h-inden-1-one oxime | Human | 3060 | |
| BRAF | RAF | TKL | 3idp | A | | n~1~-(4-chlorophenyl)-6-methyl-n~5~-[3-(7h-purin-6-yl)pyridin-2-yl]isoquinoline-1,5-diamine | Human | 3077 | |
| BRAF | RAF | TKL | 3idp | B | | n~1~-(4-chlorophenyl)-6-methyl-n~5~-[3-(7h-purin-6-yl)pyridin-2-yl]isoquinoline-1,5-diamine | Human | 3121 | |
| BRAF | RAF | TKL | 3ii5 | A | | n-[3-(3-{4-[(dimethylamino)methyl]phenyl}pyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-3-(trifluoromethyl)benzamide | Human | 3116 | |
| BRAF | RAF | TKL | 3ii5 | B | | n-[3-(3-{4-[(dimethylamino)methyl]phenyl}pyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-3-(trifluoromethyl)benzamide | Human | 3076 | |
| BRAF | RAF | TKL | 3og7 | A | | n-(3-{[5-(4-chlorophenyl)-1h-pyrrolo[2,3-b]pyridin-3-yl]carbonyl}-2,4-difluorophenyl)propane-1-sulfonamide | Human | 3113 | |
| BRAF | RAF | TKL | 3og7 | B | | - | Human | 3140 | |
| BRAF | RAF | TKL | 3ppj | A | | methyl 3-{[(5s)-1-(hydroxyamino)-5h-inden-5-yl]amino}furo[2,3-c]pyridine-2-carboxylate | Human | 3091 | |
| BRAF | RAF | TKL | 3ppj | B | | methyl 3-{[(5s)-1-(hydroxyamino)-5h-inden-5-yl]amino}furo[2,3-c]pyridine-2-carboxylate | Human | 3087 | |
| BRAF | RAF | TKL | 3ppk | A | | 3-[(5-hydroxynaphthalen-2-yl)amino]-n-(pyrimidin-4-yl)furo[2,3-c]pyridine-2-carboxamide | Human | 3106 | |
| BRAF | RAF | TKL | 3ppk | B | | 3-[(5-hydroxynaphthalen-2-yl)amino]-n-(pyrimidin-4-yl)furo[2,3-c]pyridine-2-carboxamide | Human | 3092 | |
| BRAF | RAF | TKL | 3prf | A | | 2-chloro-5-{[2-(pyrimidin-2-yl)furo[2,3-c]pyridin-3-yl]amino}phenol | Human | 3129 | |
| BRAF | RAF | TKL | 3prf | B | | 2-chloro-5-{[2-(pyrimidin-2-yl)furo[2,3-c]pyridin-3-yl]amino}phenol | Human | 3139 | |
| BRAF | RAF | TKL | 3pri | A | | 3-(4-{[2-(pyrimidin-2-yl)furo[2,3-c]pyridin-3-yl]amino}-1h-indazol-3-yl)propan-1-ol | Human | 3093 | |
| BRAF | RAF | TKL | 3pri | B | | 3-(4-{[2-(pyrimidin-2-yl)furo[2,3-c]pyridin-3-yl]amino}-1h-indazol-3-yl)propan-1-ol | Human | 3103 | |
| BRAF | RAF | TKL | 3psb | A | | ethyl 3-{[1-(hydroxyamino)-2h-inden-5-yl]amino}thieno[2,3-c]pyridine-2-carboxylate | Human | 3111 | |
| BRAF | RAF | TKL | 3psb | B | | ethyl 3-{[1-(hydroxyamino)-2h-inden-5-yl]amino}thieno[2,3-c]pyridine-2-carboxylate | Human | 3125 | |
| BRAF | RAF | TKL | 3psd | A | | 6-[1-(piperidin-4-yl)-3-(pyridin-4-yl)-1h-pyrazol-4-yl]indeno[1,2-c]pyrazole | Human | 3142 | |
| BRAF | RAF | TKL | 3psd | B | | 6-[1-(piperidin-4-yl)-3-(pyridin-4-yl)-1h-pyrazol-4-yl]indeno[1,2-c]pyrazole | Human | 3083 | |
| BRAF | RAF | TKL | 3q4c | A | | [(1,2,3,4,5,6-eta)-(1s,2r,3r,4r,5s,6s)-1-carboxycyclohexane-1,2,3,4,5,6-hexayl](chloro)(3-methyl-5,7-dioxo-6,7-dihydro-5h-pyrido[2,3-a]pyrrolo[3,4-c]carbazol-12-ide-kappa~2~n~1~,n~12~)ruthenium(1+) | Human | 7251 | |
| BRAF | RAF | TKL | 3q4c | B | | - | Human | 7250 | |
| BRAF | RAF | TKL | 3q96 | A | | (2s)-n-[3-(2-aminopropan-2-yl)-5-(trifluoromethyl)phenyl]-7-[(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-4-yl)oxy]-1,2,3,4-tetrahydronaphthalene-2-carboxamide | Human | 3072 | |
| BRAF | RAF | TKL | 3q96 | B | | (2s)-n-[3-(2-aminopropan-2-yl)-5-(trifluoromethyl)phenyl]-7-[(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-4-yl)oxy]-1,2,3,4-tetrahydronaphthalene-2-carboxamide | Human | 3089 | |
| BRAF | RAF | TKL | 3skc | A | | 2,6-difluoro-n-[(5s)-3-methoxy-5h-pyrazolo[3,4-b]pyridin-5-yl]-3-[(phenylsulfonyl)amino]benzamide | Human | 3100 | |
| BRAF | RAF | TKL | 3skc | B | | 2,6-difluoro-n-[(5s)-3-methoxy-5h-pyrazolo[3,4-b]pyridin-5-yl]-3-[(phenylsulfonyl)amino]benzamide | Human | 3128 | |
| BRAF | RAF | TKL | 3tv4 | A | | n-(6-amino-5-bromopyridin-3-yl)-2,6-difluoro-3-[(propylsulfonyl)amino]benzamide | Human | 3054 | |
| BRAF | RAF | TKL | 3tv4 | B | | n-(6-amino-5-bromopyridin-3-yl)-2,6-difluoro-3-[(propylsulfonyl)amino]benzamide | Human | 3133 | |
| BRAF | RAF | TKL | 3tv6 | A | | 2,6-difluoro-n-(3-methoxy-2h-pyrazolo[3,4-b]pyridin-5-yl)-3-[(propylsulfonyl)amino]benzamide | Human | 3080 | |
| BRAF | RAF | TKL | 3tv6 | B | | 2,6-difluoro-n-(3-methoxy-2h-pyrazolo[3,4-b]pyridin-5-yl)-3-[(propylsulfonyl)amino]benzamide | Human | 3136 | |
| BRAF | RAF | TKL | 4cqe | A | | n-{4-[2-(1-cyclopropylpiperidin-4-yl)-4-(3-{[(2,5-difluorophenyl)sulfonyl]amino}-2-fluorophenyl)-1,3-thiazol-5-yl]pyridin-2-yl}acetamide | Human | 3088 | |
| BRAF | RAF | TKL | 4cqe | B | | n-{4-[2-(1-cyclopropylpiperidin-4-yl)-4-(3-{[(2,5-difluorophenyl)sulfonyl]amino}-2-fluorophenyl)-1,3-thiazol-5-yl]pyridin-2-yl}acetamide | Human | 3107 | |
| BRAF | RAF | TKL | 4dbn | A | | 2-chloro-3-(1-cyanocyclopropyl)-n-[5-({2-[(cyclopropylcarbonyl)amino][1,3]thiazolo[5,4-b]pyridin-5-yl}oxy)-2-fluorophenyl]benzamide | Human | 3052 | |
| BRAF | RAF | TKL | 4dbn | B | | 2-chloro-3-(1-cyanocyclopropyl)-n-[5-({2-[(cyclopropylcarbonyl)amino][1,3]thiazolo[5,4-b]pyridin-5-yl}oxy)-2-fluorophenyl]benzamide | Human | 3070 | |
| BRAF | RAF | TKL | 4e26 | A | | 5-chloro-7-[(r)-furan-2-yl(pyridin-2-ylamino)methyl]quinolin-8-ol | Human | 3108 | |
| BRAF | RAF | TKL | 4e26 | B | | 5-chloro-7-[(r)-furan-2-yl(pyridin-2-ylamino)methyl]quinolin-8-ol | Human | 3102 | |
| BRAF | RAF | TKL | 4e4x | A | | n-(2,4-difluoro-3-{2-[(3-hydroxypropyl)amino]-8-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-6-yl}phenyl)propane-1-sulfonamide | Human | 3051 | |
| BRAF | RAF | TKL | 4e4x | B | | n-(2,4-difluoro-3-{2-[(3-hydroxypropyl)amino]-8-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-6-yl}phenyl)propane-1-sulfonamide | Human | 3104 | |
| BRAF | RAF | TKL | 4ehe | A | | 4-amino-n-{2,6-difluoro-3-[(propylsulfonyl)amino]phenyl}thieno[3,2-d]pyrimidine-7-carboxamide | Human | 3112 | |
| BRAF | RAF | TKL | 4ehe | B | | 4-amino-n-{2,6-difluoro-3-[(propylsulfonyl)amino]phenyl}thieno[3,2-d]pyrimidine-7-carboxamide | Human | 3082 | |
| BRAF | RAF | TKL | 4ehg | A | | n-{2,4-difluoro-3-[({6-[(2-hydroxyethyl)amino]pyrimidin-4-yl}carbamoyl)amino]phenyl}propane-1-sulfonamide | Human | 3064 | |
| BRAF | RAF | TKL | 4ehg | B | | n-{2,4-difluoro-3-[({6-[(2-hydroxyethyl)amino]pyrimidin-4-yl}carbamoyl)amino]phenyl}propane-1-sulfonamide | Human | 3078 | |
| BRAF | RAF | TKL | 4fc0 | A | | 2-chloro-3-[(2-cyanopropan-2-yl)oxy]-n-{5-[{2-[(cyclopropylcarbonyl)amino][1,3]thiazolo[5,4-b]pyridin-5-yl}(methyl)amino]-2-fluorophenyl}benzamide | Human | 3131 | |
| BRAF | RAF | TKL | 4fc0 | B | | 2-chloro-3-[(2-cyanopropan-2-yl)oxy]-n-{5-[{2-[(cyclopropylcarbonyl)amino][1,3]thiazolo[5,4-b]pyridin-5-yl}(methyl)amino]-2-fluorophenyl}benzamide | Human | 3069 | |
| BRAF | RAF | TKL | 4fk3 | A | | n-{2,4-difluoro-3-[(5-pyridin-3-yl-1h-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]phenyl}ethanesulfonamide | Human | 3118 | |
| BRAF | RAF | TKL | 4fk3 | B | | - | Human | 3068 | |
| BRAF | RAF | TKL | 4g9c | A | | 3-{[3-(2-cyanopropan-2-yl)benzoyl]amino}-2,6-difluoro-n-(3-methoxy-2h-pyrazolo[3,4-b]pyridin-5-yl)benzamide | Human | 3084 | |
| BRAF | RAF | TKL | 4g9c | B | | 3-{[3-(2-cyanopropan-2-yl)benzoyl]amino}-2,6-difluoro-n-(3-methoxy-2h-pyrazolo[3,4-b]pyridin-5-yl)benzamide | Human | 3067 | |
| BRAF | RAF | TKL | 4g9r | A | | 3-(2-cyanopropan-2-yl)-n-{4-methyl-3-[(3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]phenyl}benzamide | Human | 3130 | |
| BRAF | RAF | TKL | 4g9r | B | | 3-(2-cyanopropan-2-yl)-n-{4-methyl-3-[(3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]phenyl}benzamide | Human | 3101 | |
| BRAF | RAF | TKL | 4h58 | A | A | n-(4-{[(2-methoxyethyl)amino]methyl}phenyl)-6-(pyridin-4-yl)quinazolin-2-amine | Human | 3137 | |
| BRAF | RAF | TKL | 4h58 | A | B | n-(4-{[(2-methoxyethyl)amino]methyl}phenyl)-6-(pyridin-4-yl)quinazolin-2-amine | Human | 3110 | |
| BRAF | RAF | TKL | 4h58 | B | A | - | Human | 3097 | |
| BRAF | RAF | TKL | 4h58 | B | B | - | Human | 3120 | |
| BRAF | RAF | TKL | 4h58 | C | A | - | Human | 3056 | |
| BRAF | RAF | TKL | 4h58 | C | B | - | Human | 3114 | |
| BRAF | RAF | TKL | 4jvg | A | | 1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea | Human | 3134 | |
| BRAF | RAF | TKL | 4jvg | B | | 1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea | Human | 3085 | |
| BRAF | RAF | TKL | 4jvg | C | | 1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea | Human | 3050 | |
| BRAF | RAF | TKL | 4jvg | D | | 1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea | Human | 3059 | |
| BRAF | RAF | TKL | 4ksp | A | | n-{7-cyano-6-[4-fluoro-3-({[3-(trifluoromethyl)phenyl]acetyl}amino)phenoxy]-1,3-benzothiazol-2-yl}cyclopropanecarboxamide | Human | 3081 | |
| BRAF | RAF | TKL | 4ksp | B | | n-{7-cyano-6-[4-fluoro-3-({[3-(trifluoromethyl)phenyl]acetyl}amino)phenoxy]-1,3-benzothiazol-2-yl}cyclopropanecarboxamide | Human | 3066 | |
| BRAF | RAF | TKL | 4ksq | A | | n-{7-cyano-6-[4-fluoro-3-({[3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-1,3-benzothiazol-2-yl}cyclopropanecarboxamide | Human | 3065 | |
| BRAF | RAF | TKL | 4ksq | B | | n-{7-cyano-6-[4-fluoro-3-({[3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-1,3-benzothiazol-2-yl}cyclopropanecarboxamide | Human | 3055 | |
| BRAF | RAF | TKL | 4mbj | A | | 2,6-difluoro-n-(1h-imidazo[4,5-b]pyridin-6-yl)-3-[(propylsulfonyl)amino]benzamide | Human | 3090 | |
| BRAF | RAF | TKL | 4mbj | B | | 2,6-difluoro-n-(1h-imidazo[4,5-b]pyridin-6-yl)-3-[(propylsulfonyl)amino]benzamide | Human | 3057 | |
| BRAF | RAF | TKL | 4mne | B | A | - | Human | 3075 | |
| BRAF | RAF | TKL | 4mne | B | B | - | Human | 3061 | |
| BRAF | RAF | TKL | 4mne | C | A | - | Human | 3122 | |
| BRAF | RAF | TKL | 4mne | C | B | - | Human | 3058 | |
| BRAF | RAF | TKL | 4mne | F | A | - | Human | 3099 | |
| BRAF | RAF | TKL | 4mne | F | B | - | Human | 3117 | |
| BRAF | RAF | TKL | 4mne | G | A | - | Human | 3071 | |
| BRAF | RAF | TKL | 4mne | G | B | - | Human | 3073 | |
| BRAF | RAF | TKL | 4mnf | A | A | 2-{4-[(1e)-1-(hydroxyimino)-2,3-dihydro-1h-inden-5-yl]-3-(pyridin-4-yl)-1h-pyrazol-1-yl}ethanol | Human | 3096 | |
| BRAF | RAF | TKL | 4mnf | A | B | 2-{4-[(1e)-1-(hydroxyimino)-2,3-dihydro-1h-inden-5-yl]-3-(pyridin-4-yl)-1h-pyrazol-1-yl}ethanol | Human | 3141 | |
| BRAF | RAF | TKL | 4mnf | B | A | 2-{4-[(1e)-1-(hydroxyimino)-2,3-dihydro-1h-inden-5-yl]-3-(pyridin-4-yl)-1h-pyrazol-1-yl}ethanol | Human | 3124 | |
| BRAF | RAF | TKL | 4mnf | B | B | 2-{4-[(1e)-1-(hydroxyimino)-2,3-dihydro-1h-inden-5-yl]-3-(pyridin-4-yl)-1h-pyrazol-1-yl}ethanol | Human | 3098 | |
| BRAF | RAF | TKL | 4pp7 | A | | n-{2,4-difluoro-3-[methyl(3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]phenyl}propane-1-sulfonamide | Human | 3094 | |
| BRAF | RAF | TKL | 4pp7 | B | | n-{2,4-difluoro-3-[methyl(3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]phenyl}propane-1-sulfonamide | Human | 3126 | |
| BRAF | RAF | TKL | 4r5y | A | | 5-({(1r,1as,6br)-1-[5-(trifluoromethyl)-1h-benzimidazol-2-yl]-1a,6b-dihydro-1h-cyclopropa[b][1]benzofuran-5-yl}oxy)-3,4-dihydro-1,8-naphthyridin-2(1h)-one | Human | 6414 | |
| BRAF | RAF | TKL | 4r5y | B | | 5-({(1r,1as,6br)-1-[5-(trifluoromethyl)-1h-benzimidazol-2-yl]-1a,6b-dihydro-1h-cyclopropa[b][1]benzofuran-5-yl}oxy)-3,4-dihydro-1,8-naphthyridin-2(1h)-one | Human | 6413 | |
| BRAF | RAF | TKL | 4rzv | A | | n-(3-{[5-(4-chlorophenyl)-1h-pyrrolo[2,3-b]pyridin-3-yl]carbonyl}-2,4-difluorophenyl)propane-1-sulfonamide | Human | 6944 | |
| BRAF | RAF | TKL | 4rzv | B | | n-(3-{[5-(4-chlorophenyl)-1h-pyrrolo[2,3-b]pyridin-3-yl]carbonyl}-2,4-difluorophenyl)propane-1-sulfonamide | Human | 6941 | |
| BRAF | RAF | TKL | 4rzw | A | | 3-(2-cyanopropan-2-yl)-n-{4-methyl-3-[(3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]phenyl}benzamide | Human | 6939 | |
| BRAF | RAF | TKL | 4rzw | B | | 3-(2-cyanopropan-2-yl)-n-{4-methyl-3-[(3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]phenyl}benzamide | Human | 6942 | |
| BRAF | RAF | TKL | 4wo5 | A | | n-{3-[(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl}propane-1-sulfonamide | Human | 3079 | |
| BRAF | RAF | TKL | 4wo5 | B | | n-{3-[(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl}propane-1-sulfonamide | Human | 3143 | |
| BRAF | RAF | TKL | 4xv1 | A | | n'-(3-{[5-(2-cyclopropylpyrimidin-5-yl)-1h-pyrrolo[2,3-b]pyridin-3-yl]carbonyl}-2,4-difluorophenyl)-n-ethyl-n-methylsulfuric diamide | Human | 6214 | |
| BRAF | RAF | TKL | 4xv1 | B | | - | Human | 6216 | |
| BRAF | RAF | TKL | 4xv2 | A | | dabrafenib | Human | 6213 | |
| BRAF | RAF | TKL | 4xv2 | B | | dabrafenib | Human | 6219 | |
| BRAF | RAF | TKL | 4xv3 | A | | n'-{3-[5-(2-aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-4-yl]-2-fluorophenyl}-n-ethyl-n-methylsulfuric diamide | Human | 6217 | |
| BRAF | RAF | TKL | 4xv3 | B | | - | Human | 6218 | |
| BRAF | RAF | TKL | 4xv9 | A | A | n-{3-[(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl}-4-(trifluoromethyl)benzenesulfonamide | Human | 6220 | |
| BRAF | RAF | TKL | 4xv9 | A | B | n-{3-[(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl}-4-(trifluoromethyl)benzenesulfonamide | Human | 6215 | |
| BRAF | RAF | TKL | 4yht | A | | 3-[(5-chloro-7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]-n-methyl-4-(morpholin-4-yl)benzenesulfonamide | Human | 6442 | |
| BRAF | RAF | TKL | 4yht | B | | 3-[(5-chloro-7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]-n-methyl-4-(morpholin-4-yl)benzenesulfonamide | Human | 6443 | |
| BRAF | RAF | TKL | 5c9c | A | A | 1-(3,3-dimethylbutyl)-3-{2-fluoro-4-methyl-5-[7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl]phenyl}urea | Human | 3123 | |
| BRAF | RAF | TKL | 5c9c | A | B | 1-(3,3-dimethylbutyl)-3-{2-fluoro-4-methyl-5-[7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl]phenyl}urea | Human | 3074 | |
| BRAF | RAF | TKL | 5c9c | B | A | 1-(3,3-dimethylbutyl)-3-{2-fluoro-4-methyl-5-[7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl]phenyl}urea | Human | 3138 | |
| BRAF | RAF | TKL | 5c9c | B | B | 1-(3,3-dimethylbutyl)-3-{2-fluoro-4-methyl-5-[7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl]phenyl}urea | Human | 3119 | |
| BRAF | RAF | TKL | 5csw | A | | dabrafenib | Human | 6433 | |
| BRAF | RAF | TKL | 5csw | B | | dabrafenib | Human | 6431 | |
| BRAF | RAF | TKL | 5csx | A | | n-(3-{5-[(1-ethylpiperidin-4-yl)(methyl)amino]-3-(pyrimidin-5-yl)-1h-pyrrolo[3,2-b]pyridin-1-yl}-2,4-difluorophenyl)propane-1-sulfonamide | Human | 6432 | |
| BRAF | RAF | TKL | 5ct7 | A | | 1-methyl-5-({2-[5-(trifluoromethyl)-1h-imidazol-2-yl]pyridin-4-yl}oxy)-n-[4-(trifluoromethyl)phenyl]-1h-benzimidazol-2-amine | Human | 6032 | |
| BRAF | RAF | TKL | 5ct7 | B | | 1-methyl-5-({2-[5-(trifluoromethyl)-1h-imidazol-2-yl]pyridin-4-yl}oxy)-n-[4-(trifluoromethyl)phenyl]-1h-benzimidazol-2-amine | Human | 6033 | |
| BRAF | RAF | TKL | 5fd2 | A | | 6-[2-[[3-(dimethylsulfamoylamino)-2,6-bis(fluoranyl)phenyl]amino]pyridin-3-yl]-7~{h}-purine | Human | 6603 | |
| BRAF | RAF | TKL | 5fd2 | B | | 6-[2-[[3-(dimethylsulfamoylamino)-2,6-bis(fluoranyl)phenyl]amino]pyridin-3-yl]-7~{h}-purine | Human | 6602 | |
| BRAF | RAF | TKL | 5hi2 | A | | 4-{4-[({[4-chloro-3-(trifluoromethyl)phenyl]amino}carbonyl)amino]phenoxy}-n-methylpyridine-2-carboxamide | Human | 6515 | |
| BRAF | RAF | TKL | 5hid | A | A | 3-(2-cyanopropan-2-yl)-n-{4-methyl-3-[(3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]phenyl}benzamide | Human | 6506 | |
| BRAF | RAF | TKL | 5hid | A | B | 3-(2-cyanopropan-2-yl)-n-{4-methyl-3-[(3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]phenyl}benzamide | Human | 6512 | |
| BRAF | RAF | TKL | 5hid | B | A | 3-(2-cyanopropan-2-yl)-n-{4-methyl-3-[(3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]phenyl}benzamide | Human | 6511 | |
| BRAF | RAF | TKL | 5hid | B | B | 3-(2-cyanopropan-2-yl)-n-{4-methyl-3-[(3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]phenyl}benzamide | Human | 6517 | |
| BRAF | RAF | TKL | 5hie | A | A | dabrafenib | Human | 6516 | |
| BRAF | RAF | TKL | 5hie | A | B | dabrafenib | Human | 6508 | |
| BRAF | RAF | TKL | 5hie | B | A | dabrafenib | Human | 6509 | |
| BRAF | RAF | TKL | 5hie | B | B | dabrafenib | Human | 6505 | |
| BRAF | RAF | TKL | 5hie | C | A | dabrafenib | Human | 6513 | |
| BRAF | RAF | TKL | 5hie | C | B | dabrafenib | Human | 6507 | |
| BRAF | RAF | TKL | 5hie | D | A | dabrafenib | Human | 6510 | |
| BRAF | RAF | TKL | 5hie | D | B | dabrafenib | Human | 6514 | |
| BRAF | RAF | TKL | 5ita | A | | n-{2-cyano-3-[(3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]phenyl}propane-1-sulfonamide | Human | 6940 | |
| BRAF | RAF | TKL | 5ita | B | | n-{2-cyano-3-[(3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]phenyl}propane-1-sulfonamide | Human | 6943 | |
| BRAF | RAF | TKL | 5jrq | A | | (3-{[dihydroxy(propyl)-lambda~4~-sulfanyl]amino}-2,6-difluorophenyl)[5-(4-methoxyphenyl)-1h-pyrrolo[2,3-b]pyridin-3-yl]methanone | Human | 7061 | |
| BRAF | RAF | TKL | 5jrq | B | | (3-{[dihydroxy(propyl)-lambda~4~-sulfanyl]amino}-2,6-difluorophenyl)[5-(4-methoxyphenyl)-1h-pyrrolo[2,3-b]pyridin-3-yl]methanone | Human | 7054 | |
| BRAF | RAF | TKL | 5jsm | A | A | - | Human | 7056 | |
| BRAF | RAF | TKL | 5jsm | A | B | - | Human | 7058 | |
| BRAF | RAF | TKL | 5jsm | B | A | n,n'-{ethane-1,2-diylbis[oxyethane-2,1-diyloxy-4,1-phenylene-1h-pyrrolo[2,3-b]pyridine-5,3-diylcarbonyl(2,4-difluoro-3,1-phenylene)]}di(propane-1-sulfonamide) | Human | 7060 | |
| BRAF | RAF | TKL | 5jsm | B | B | n,n'-{ethane-1,2-diylbis[oxyethane-2,1-diyloxy-4,1-phenylene-1h-pyrrolo[2,3-b]pyridine-5,3-diylcarbonyl(2,4-difluoro-3,1-phenylene)]}di(propane-1-sulfonamide) | Human | 7062 | |
| BRAF | RAF | TKL | 5jsm | C | A | n,n'-{ethane-1,2-diylbis[oxyethane-2,1-diyloxy-4,1-phenylene-1h-pyrrolo[2,3-b]pyridine-5,3-diylcarbonyl(2,4-difluoro-3,1-phenylene)]}di(propane-1-sulfonamide) | Human | 7059 | |
| BRAF | RAF | TKL | 5jsm | C | B | n,n'-{ethane-1,2-diylbis[oxyethane-2,1-diyloxy-4,1-phenylene-1h-pyrrolo[2,3-b]pyridine-5,3-diylcarbonyl(2,4-difluoro-3,1-phenylene)]}di(propane-1-sulfonamide) | Human | 7063 | |
| BRAF | RAF | TKL | 5jsm | D | A | - | Human | 7055 | |
| BRAF | RAF | TKL | 5jsm | D | B | - | Human | 7053 | |
| BRAF | RAF | TKL | 5jt2 | A | | 2,2'-oxybis[n-({4-[3-(3-{[dihydroxy(propyl)-lambda~4~-sulfanyl]amino}-2,6-difluorobenzene-1-carbonyl)-1h-pyrrolo[2,3-b]pyridin-5-yl]phenyl}methyl)acetamide] | Human | 7065 | |
| BRAF | RAF | TKL | 5jt2 | B | | - | Human | 7057 | |
| BRAF | RAF | TKL | 5jt2 | C | | 2,2'-oxybis[n-({4-[3-(3-{[dihydroxy(propyl)-lambda~4~-sulfanyl]amino}-2,6-difluorobenzene-1-carbonyl)-1h-pyrrolo[2,3-b]pyridin-5-yl]phenyl}methyl)acetamide] | Human | 7064 | |
| BRAF | RAF | TKL | 5jt2 | D | | - | Human | 7066 | |
| BRAF | RAF | TKL | 5val | A | | n-(3-tert-butylphenyl)-4-methyl-3-[6-(morpholin-4-yl)pyrimidin-4-yl]benzamide | Human | 8190 | |
| BRAF | RAF | TKL | 5val | B | | n-(3-tert-butylphenyl)-4-methyl-3-[6-(morpholin-4-yl)pyrimidin-4-yl]benzamide | Human | 8188 | |
| BRAF | RAF | TKL | 5vam | A | A | n-{2-methyl-5'-(morpholin-4-yl)-6'-[(oxan-4-yl)oxy][3,3'-bipyridin]-5-yl}-3-(trifluoromethyl)benzamide | Human | 8185 | |
| BRAF | RAF | TKL | 5vam | A | B | n-{2-methyl-5'-(morpholin-4-yl)-6'-[(oxan-4-yl)oxy][3,3'-bipyridin]-5-yl}-3-(trifluoromethyl)benzamide | Human | 8189 | |
| BRAF | RAF | TKL | 5vam | B | A | n-{2-methyl-5'-(morpholin-4-yl)-6'-[(oxan-4-yl)oxy][3,3'-bipyridin]-5-yl}-3-(trifluoromethyl)benzamide | Human | 8186 | |
| BRAF | RAF | TKL | 5vam | B | B | n-{2-methyl-5'-(morpholin-4-yl)-6'-[(oxan-4-yl)oxy][3,3'-bipyridin]-5-yl}-3-(trifluoromethyl)benzamide | Human | 8187 | |
| BRAF | RAF | TKL | 6b8u | A | | ~{n}-[3-(2-acetamidoimidazo[1,2-a]pyridin-6-yl)-4-methyl-phenyl]-3-(trifluoromethyl)benzamide | Human | 8679 | |
| BRAF | RAF | TKL | 6b8u | B | | ~{n}-[3-(2-acetamidoimidazo[1,2-a]pyridin-6-yl)-4-methyl-phenyl]-3-(trifluoromethyl)benzamide | Human | 8678 | |
| BRAF | RAF | TKL | 6cad | A | | 1-(propan-2-yl)-3-({3-[3-(trifluoromethyl)phenyl]isoquinolin-8-yl}ethynyl)-1h-pyrazolo[3,4-d]pyrimidin-4-amine | Human | 9576 | |
| BRAF | RAF | TKL | 6cad | B | | 1-(propan-2-yl)-3-({3-[3-(trifluoromethyl)phenyl]isoquinolin-8-yl}ethynyl)-1h-pyrazolo[3,4-d]pyrimidin-4-amine | Human | 9575 | |
| BRAF | RAF | TKL | 6n0p | A | A | n-{3-[2-(2-hydroxyethoxy)-6-(morpholin-4-yl)pyridin-4-yl]-4-methylphenyl}-2-(trifluoromethyl)pyridine-4-carboxamide | Human | 11597 | |
| BRAF | RAF | TKL | 6n0p | A | B | n-{3-[2-(2-hydroxyethoxy)-6-(morpholin-4-yl)pyridin-4-yl]-4-methylphenyl}-2-(trifluoromethyl)pyridine-4-carboxamide | Human | 11596 | |
| BRAF | RAF | TKL | 6n0p | B | A | n-{3-[2-(2-hydroxyethoxy)-6-(morpholin-4-yl)pyridin-4-yl]-4-methylphenyl}-2-(trifluoromethyl)pyridine-4-carboxamide | Human | 11594 | |
| BRAF | RAF | TKL | 6n0p | B | B | n-{3-[2-(2-hydroxyethoxy)-6-(morpholin-4-yl)pyridin-4-yl]-4-methylphenyl}-2-(trifluoromethyl)pyridine-4-carboxamide | Human | 11595 | |
| BRAF | RAF | TKL | 6n0q | A | A | n-[4-methyl-3-(1-methyl-2-oxo-2,3-dihydro-1h-benzimidazol-5-yl)phenyl]-3-(trifluoromethyl)benzamide | Human | 11771 | |
| BRAF | RAF | TKL | 6n0q | A | B | n-[4-methyl-3-(1-methyl-2-oxo-2,3-dihydro-1h-benzimidazol-5-yl)phenyl]-3-(trifluoromethyl)benzamide | Human | 11768 | |
| BRAF | RAF | TKL | 6n0q | B | A | n-[4-methyl-3-(1-methyl-2-oxo-2,3-dihydro-1h-benzimidazol-5-yl)phenyl]-3-(trifluoromethyl)benzamide | Human | 11770 | |
| BRAF | RAF | TKL | 6n0q | B | B | n-[4-methyl-3-(1-methyl-2-oxo-2,3-dihydro-1h-benzimidazol-5-yl)phenyl]-3-(trifluoromethyl)benzamide | Human | 11769 | |
| BRAF | RAF | TKL | 6nsq | A | | 5-[(4-amino-1-ethyl-1h-pyrazolo[3,4-d]pyrimidin-3-yl)ethynyl]-n-(4-chlorophenyl)-6-methylisoquinolin-1-amine | Human | 11328 | |
| BRAF | RAF | TKL | 6nsq | B | | 5-[(4-amino-1-ethyl-1h-pyrazolo[3,4-d]pyrimidin-3-yl)ethynyl]-n-(4-chlorophenyl)-6-methylisoquinolin-1-amine | Human | 11329 | |
| BRAF | RAF | TKL | 6nyb | A | | phosphothiophosphoric acid-adenylate ester | Human | 11708 | |
| BRAF | RAF | TKL | 6p3d | A | | 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-n-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide | Human | 12809 | |
| BRAF | RAF | TKL | 6p7g | A | | 3-[(imidazo[1,2-b]pyridazin-3-yl)ethynyl]-4-methyl-n-[4-({[2-(morpholin-4-yl)ethyl]amino}methyl)-3-(trifluoromethyl)phenyl]benzamide | Human | 12810 | |
| BRAF | RAF | TKL | 6p7g | B | | 3-[(imidazo[1,2-b]pyridazin-3-yl)ethynyl]-4-methyl-n-[4-({[2-(morpholin-4-yl)ethyl]amino}methyl)-3-(trifluoromethyl)phenyl]benzamide | Human | 12806 | |
| BRAF | RAF | TKL | 6p7g | C | | 3-[(imidazo[1,2-b]pyridazin-3-yl)ethynyl]-4-methyl-n-[4-({[2-(morpholin-4-yl)ethyl]amino}methyl)-3-(trifluoromethyl)phenyl]benzamide | Human | 12807 | |
| BRAF | RAF | TKL | 6p7g | D | | 3-[(imidazo[1,2-b]pyridazin-3-yl)ethynyl]-4-methyl-n-[4-({[2-(morpholin-4-yl)ethyl]amino}methyl)-3-(trifluoromethyl)phenyl]benzamide | Human | 12808 | |
| BRAF | RAF | TKL | 6pp9 | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 11711 | |
| BRAF | RAF | TKL | 6pp9 | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 11709 | |
| BRAF | RAF | TKL | 6q0j | A | A | - | Human | 11704 | |
| BRAF | RAF | TKL | 6q0j | A | B | - | Human | 11701 | |
| BRAF | RAF | TKL | 6q0j | B | A | - | Human | 11703 | |
| BRAF | RAF | TKL | 6q0j | B | B | - | Human | 11712 | |
| BRAF | RAF | TKL | 6q0k | A | | - | Human | 11706 | |
| BRAF | RAF | TKL | 6q0k | B | | - | Human | 11710 | |
| BRAF | RAF | TKL | 6q0t | A | A | - | Human | 11705 | |
| BRAF | RAF | TKL | 6q0t | A | B | - | Human | 11707 | |
| BRAF | RAF | TKL | 6q0t | B | A | - | Human | 11702 | |
| BRAF | RAF | TKL | 6q0t | B | B | - | Human | 11700 | |
| BRAF | RAF | TKL | 6u2g | B | | phosphomethylphosphonic acid adenylate ester | Human | 11567 | |
| BRAF | RAF | TKL | 6u2h | C | A | 2-{4-[(1e)-1-(hydroxyimino)-2,3-dihydro-1h-inden-5-yl]-3-(pyridin-4-yl)-1h-pyrazol-1-yl}ethanol | Human | 11568 | |
| BRAF | RAF | TKL | 6u2h | D | A | 2-{4-[(1e)-1-(hydroxyimino)-2,3-dihydro-1h-inden-5-yl]-3-(pyridin-4-yl)-1h-pyrazol-1-yl}ethanol | Human | 11569 | |
| BRAF | RAF | TKL | 6uan | B | | - | Human | 11641 | |
| BRAF | RAF | TKL | 6uan | C | | - | Human | 11642 | |
| BRAF | RAF | TKL | 6uuo | A | | 1-[4-{[1-(3-{[dihydroxy(propyl)-lambda~4~-sulfanyl]amino}-2,6-difluorophenyl)-3-(pyrimidin-5-yl)-1h-pyrrolo[3,2-b]pyridin-5-yl](methyl)amino}pyridin-1(4h)-yl]ethan-1-one | Human | 12347 | |
| BRAF | RAF | TKL | 6uuo | B | | 1-[4-{[1-(3-{[dihydroxy(propyl)-lambda~4~-sulfanyl]amino}-2,6-difluorophenyl)-3-(pyrimidin-5-yl)-1h-pyrrolo[3,2-b]pyridin-5-yl](methyl)amino}pyridin-1(4h)-yl]ethan-1-one | Human | 12346 | |
| BRAF | RAF | TKL | 6v2u | A | | dabrafenib | Human | 13034 | |
| BRAF | RAF | TKL | 6v2u | B | | dabrafenib | Human | 13031 | |
| BRAF | RAF | TKL | 6v2w | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 13026 | |
| BRAF | RAF | TKL | 6v2w | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 13032 | |
| BRAF | RAF | TKL | 6v34 | A | | 6-amino-5-chloro-n-[(1r)-1-(5-{[5-chloro-4-(trifluoromethyl)pyridin-2-yl]carbamoyl}-1,3-thiazol-2-yl)ethyl]pyrimidine-4-carboxamide | Human | 13200 | |
| BRAF | RAF | TKL | 6v34 | B | | 6-amino-5-chloro-n-[(1r)-1-(5-{[5-chloro-4-(trifluoromethyl)pyridin-2-yl]carbamoyl}-1,3-thiazol-2-yl)ethyl]pyrimidine-4-carboxamide | Human | 13199 | |
| BRAF | RAF | TKL | 6xag | C | A | - | Human | 12922 | |
| BRAF | RAF | TKL | 6xag | D | A | - | Human | 12921 | |
| BRAF | RAF | TKL | 6xfp | A | A | 4-amino-n-{1-[(3-chloro-2-fluorophenyl)amino]-6-methylisoquinolin-5-yl}thieno[3,2-d]pyrimidine-7-carboxamide | Human | 13403 | |
| BRAF | RAF | TKL | 6xfp | A | B | 4-amino-n-{1-[(3-chloro-2-fluorophenyl)amino]-6-methylisoquinolin-5-yl}thieno[3,2-d]pyrimidine-7-carboxamide | Human | 13404 | |
| BRAF | RAF | TKL | 6xlo | A | | 3-(2-cyanopropan-2-yl)-n-[2-fluoro-4-methyl-5-(7-methyl-8-oxo-7,8-dihydropyrido[2,3-d]pyridazin-3-yl)phenyl]benzamide | Human | 13618 | |
| BRAF | RAF | TKL | 7k0v | A | A | n-(3,3-dimethylbutyl)-n'-{2-fluoro-5-[(5-fluoro-3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]-4-methylphenyl}urea | Human | 13617 | |
| BRAF | RAF | TKL | 7k0v | A | B | n-(3,3-dimethylbutyl)-n'-{2-fluoro-5-[(5-fluoro-3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]-4-methylphenyl}urea | Human | 13616 | |
| BRAF | RAF | TKL | 7m0t | A | | phosphoaminophosphonic acid-adenylate ester | Human | 13525 | |
| BRAF | RAF | TKL | 7m0u | A | | phosphoaminophosphonic acid-adenylate ester | Human | 13527 | |
| BRAF | RAF | TKL | 7m0v | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 13526 | |
| BRAF | RAF | TKL | 7m0v | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 13522 | |
| BRAF | RAF | TKL | 7m0w | A | | phosphoaminophosphonic acid-adenylate ester | Human | 13528 | |
| BRAF | RAF | TKL | 7m0x | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 13524 | |
| BRAF | RAF | TKL | 7m0x | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 13523 | |
| BRAF | RAF | TKL | 7m0y | A | | phosphoaminophosphonic acid-adenylate ester | Human | 13520 | |
| BRAF | RAF | TKL | 7m0z | A | | phosphoaminophosphonic acid-adenylate ester | Human | 13521 | |
| BRAF | RAF | TKL | 7mfd | A | | - | Human | 14077 | |
| BRAF | RAF | TKL | 7mfe | A | | - | Human | 14078 | |
| BRAF | RAF | TKL | 7p3v | A | | ~{n}-[3-[5-(2-azanylpyrimidin-4-yl)-2-[(3~{s})-morpholin-3-yl]-1,3-thiazol-4-yl]-2-fluoranyl-phenyl]-2,5-bis(fluoranyl)benzenesulfonamide | Human | 13961 | |
| BRAF | RAF | TKL | 7shv | A | A | 2-{4-[(1e)-1-(hydroxyimino)-2,3-dihydro-1h-inden-5-yl]-3-(pyridin-4-yl)-1h-pyrazol-1-yl}ethanol | Human | 14482 | |
| BRAF | RAF | TKL | 7shv | A | B | 2-{4-[(1e)-1-(hydroxyimino)-2,3-dihydro-1h-inden-5-yl]-3-(pyridin-4-yl)-1h-pyrazol-1-yl}ethanol | Human | 14481 | |
| BRAF | RAF | TKL | 8c7x | A | A | ~{n}-[3-[(5-chloranyl-1~{h}-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-bis(fluoranyl)phenyl]-3-(2-cyanopropan-2-yl)benzamide | Human | 14630 | |
| BRAF | RAF | TKL | 8c7x | A | B | ~{n}-[3-[(5-chloranyl-1~{h}-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-bis(fluoranyl)phenyl]-3-(2-cyanopropan-2-yl)benzamide | Human | 14627 | |
| BRAF | RAF | TKL | 8c7y | A | A | ~{n}-[3-[(5-chloranyl-1~{h}-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-bis(fluoranyl)phenyl]-3-(2-cyanopropan-2-yl)benzamide | Human | 14629 | |
| BRAF | RAF | TKL | 8c7y | A | B | ~{n}-[3-[(5-chloranyl-1~{h}-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-bis(fluoranyl)phenyl]-3-(2-cyanopropan-2-yl)benzamide | Human | 14628 | |
| BRAF | RAF | TKL | 8dgs | A | A | phosphothiophosphoric acid-adenylate ester | Human | 14831 | |
| BRAF | RAF | TKL | 8dgs | A | B | phosphothiophosphoric acid-adenylate ester | Human | 14829 | |
| BRAF | RAF | TKL | 8dgt | A | A | phosphothiophosphoric acid-adenylate ester | Human | 14832 | |
| BRAF | RAF | TKL | 8dgt | A | B | phosphothiophosphoric acid-adenylate ester | Human | 14830 | |
| BRAF | RAF | TKL | 8f7o | A | A | 6-amino-5-chloro-n-[(1r)-1-(5-{[5-chloro-4-(trifluoromethyl)pyridin-2-yl]carbamoyl}-1,3-thiazol-2-yl)ethyl]pyrimidine-4-carboxamide | Human | 14704 | |
| BRAF | RAF | TKL | 8f7o | A | B | 6-amino-5-chloro-n-[(1r)-1-(5-{[5-chloro-4-(trifluoromethyl)pyridin-2-yl]carbamoyl}-1,3-thiazol-2-yl)ethyl]pyrimidine-4-carboxamide | Human | 14703 | |
| BRAF | RAF | TKL | 8f7p | A | A | n-{3-[2-(2-hydroxyethoxy)-6-(morpholin-4-yl)pyridin-4-yl]-4-methylphenyl}-2-(trifluoromethyl)pyridine-4-carboxamide | Human | 14705 | |
| BRAF | RAF | TKL | 8f7p | A | B | n-{3-[2-(2-hydroxyethoxy)-6-(morpholin-4-yl)pyridin-4-yl]-4-methylphenyl}-2-(trifluoromethyl)pyridine-4-carboxamide | Human | 14702 | |
| BRAF | RAF | TKL | 8qqg | A | A | (3~{s})-~{n}-[4-methyl-3-[2-morpholin-4-yl-6-[[(2~{r})-1-oxidanylpropan-2-yl]amino]pyridin-4-yl]phenyl]-3-[2,2,2-tris(fluoranyl)ethyl]pyrrolidine-1-carboxamide | Human | 15178 | |
| BRAF | RAF | TKL | 8qqg | A | B | (3~{s})-~{n}-[4-methyl-3-[2-morpholin-4-yl-6-[[(2~{r})-1-oxidanylpropan-2-yl]amino]pyridin-4-yl]phenyl]-3-[2,2,2-tris(fluoranyl)ethyl]pyrrolidine-1-carboxamide | Human | 15179 | |
| BRAF | RAF | TKL | 9bfb | A | A | n-{2-chloro-3-[(3,5-dimethyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]-4-fluorophenyl}-3-fluoropropane-1-sulfonamide | Human | 15365 | |
| BRAF | RAF | TKL | 9bfb | A | B | n-{2-chloro-3-[(3,5-dimethyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]-4-fluorophenyl}-3-fluoropropane-1-sulfonamide | Human | 15366 | |
| Brsk2 (BRSK2) | CAMKL | CAMK | 4ynz | A | | - | Mouse | 6293 | |
| Brsk2 (BRSK2) | CAMKL | CAMK | 4ynz | B | | - | Mouse | 6291 | |
| Brsk2 (BRSK2) | CAMKL | CAMK | 4yom | B | | - | Mouse | 6292 | |
| Btk (BTK) | Tec | TK | 4xi2 | A | | - | Mouse | 5815 | |
| Btk (BTK) | Tec | TK | 6mny | A | A | 5-amino-1-[(3r)-1-cyanopiperidin-3-yl]-3-[4-(2,4-difluorophenoxy)phenyl]-1h-pyrazole-4-carboxamide | Mouse | 11307 | |
| Btk (BTK) | Tec | TK | 6mny | A | B | 5-amino-1-[(3r)-1-cyanopiperidin-3-yl]-3-[4-(2,4-difluorophenoxy)phenyl]-1h-pyrazole-4-carboxamide | Mouse | 11308 | |
| Btk (BTK) | Tec | TK | 6mny | B | A | - | Mouse | 11306 | |
| Btk (BTK) | Tec | TK | 6mny | B | B | - | Mouse | 11309 | |
| Btk (BTK) | Tec | TK | 8fd9 | A | A | acalabrutinib | Mouse | 14836 | |
| Btk (BTK) | Tec | TK | 8fd9 | A | B | acalabrutinib | Mouse | 14835 | |
| Btk (BTK) | Tec | TK | 8ff0 | A | | 6-azanyl-9-[(3~{r})-1-[(~{e})-but-2-enoyl]pyrrolidin-3-yl]-7-(4-phenoxyphenyl)purin-8-one | Mouse | 14834 | |
| Btk (BTK) | Tec | TK | 8gmb | A | | 2-[3'-(hydroxymethyl)-1-methyl-5-({5-[(2s)-2-methyl-4-(oxetan-3-yl)piperazin-1-yl]pyridin-2-yl}amino)-6-oxo[1,6-dihydro[3,4'-bipyridine]]-2'-yl]-7,7-dimethyl-3,4,7,8-tetrahydro-2h-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-1(6h)-one | Mouse | 14999 | |
| Btk (BTK) | Tec | TK | 8s93 | A | A | 2-[3'-(hydroxymethyl)-1-methyl-5-({5-[(2s)-2-methyl-4-(oxetan-3-yl)piperazin-1-yl]pyridin-2-yl}amino)-6-oxo[1,6-dihydro[3,4'-bipyridine]]-2'-yl]-7,7-dimethyl-3,4,7,8-tetrahydro-2h-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-1(6h)-one | Mouse | 14997 | |
| Btk (BTK) | Tec | TK | 8s93 | A | B | 2-[3'-(hydroxymethyl)-1-methyl-5-({5-[(2s)-2-methyl-4-(oxetan-3-yl)piperazin-1-yl]pyridin-2-yl}amino)-6-oxo[1,6-dihydro[3,4'-bipyridine]]-2'-yl]-7,7-dimethyl-3,4,7,8-tetrahydro-2h-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-1(6h)-one | Mouse | 14996 | |
| Btk (BTK) | Tec | TK | 8s9f | A | | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Mouse | 14998 | |
| BTK | Tec | TK | 1k2p | A | | - | Human | 2918 | |
| BTK | Tec | TK | 1k2p | B | | - | Human | 2919 | |
| BTK | Tec | TK | 3gen | A | A | 4-amino-5-(4-phenoxyphenyl)-7h-pyrrolo[2,3-d]pyrimidin-7-yl-cyclopentane | Human | 2928 | |
| BTK | Tec | TK | 3gen | A | B | 4-amino-5-(4-phenoxyphenyl)-7h-pyrrolo[2,3-d]pyrimidin-7-yl-cyclopentane | Human | 2900 | |
| BTK | Tec | TK | 3k54 | A | A | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 2932 | |
| BTK | Tec | TK | 3k54 | A | B | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 2906 | |
| BTK | Tec | TK | 3ocs | A | | 4-tert-butyl-n-[2-methyl-3-(4-methyl-6-{[4-(morpholin-4-ylcarbonyl)phenyl]amino}-5-oxo-4,5-dihydropyrazin-2-yl)phenyl]benzamide | Human | 2907 | |
| BTK | Tec | TK | 3oct | A | A | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 2899 | |
| BTK | Tec | TK | 3oct | A | B | n-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide | Human | 2908 | |
| BTK | Tec | TK | 3p08 | A | | - | Human | 2905 | |
| BTK | Tec | TK | 3p08 | B | | - | Human | 2894 | |
| BTK | Tec | TK | 3pix | A | | 7-(4-methylpiperazin-1-yl)-4-[(5-methyl-1h-pyrazol-3-yl)amino]-2-(propan-2-yl)phthalazin-1(2h)-one | Human | 2927 | |
| BTK | Tec | TK | 3piy | A | | 6-({5-fluoro-2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl}amino)-2,2-dimethyl-2h-pyrido[3,2-b][1,4]oxazin-3(4h)-one | Human | 2909 | |
| BTK | Tec | TK | 3piz | A | | [5-amino-1-(2-methylphenyl)-1h-pyrazol-4-yl]{3-[1-(methylsulfonyl)piperidin-4-yl]phenyl}methanone | Human | 2922 | |
| BTK | Tec | TK | 3pj1 | A | | 3-(2,6-dichlorophenyl)-7-({4-[2-(diethylamino)ethoxy]phenyl}amino)-1-methyl-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1h)-one | Human | 2904 | |
| BTK | Tec | TK | 3pj2 | A | | 2-({4-[2-(diethylamino)ethoxy]phenyl}amino)-6-(4-fluorophenoxy)-8-methylpyrido[2,3-d]pyrimidin-7(8h)-one | Human | 2911 | |
| BTK | Tec | TK | 3pj3 | A | | 2-methyl-n-(2-phenyl-3h-imidazo[4,5-b]pyridin-6-yl)-5-{[(2e)-3-phenylprop-2-enoyl]amino}benzamide | Human | 2910 | |
| BTK | Tec | TK | 4nwm | A | A | 4-tert-butyl-n-[2-methyl-3-(6-{[4-(morpholin-4-ylcarbonyl)phenyl]amino}-7h-purin-2-yl)phenyl]benzamide | Human | 2930 | |
| BTK | Tec | TK | 4nwm | A | B | 4-tert-butyl-n-[2-methyl-3-(6-{[4-(morpholin-4-ylcarbonyl)phenyl]amino}-7h-purin-2-yl)phenyl]benzamide | Human | 2917 | |
| BTK | Tec | TK | 4nwm | B | A | 4-tert-butyl-n-[2-methyl-3-(6-{[4-(morpholin-4-ylcarbonyl)phenyl]amino}-7h-purin-2-yl)phenyl]benzamide | Human | 2898 | |
| BTK | Tec | TK | 4nwm | B | B | 4-tert-butyl-n-[2-methyl-3-(6-{[4-(morpholin-4-ylcarbonyl)phenyl]amino}-7h-purin-2-yl)phenyl]benzamide | Human | 2903 | |
| BTK | Tec | TK | 4ot5 | A | | 4-tert-butyl-n-{3-[8-({4-[(4-methylpiperazin-1-yl)carbonyl]phenyl}amino)imidazo[1,2-a]pyrazin-6-yl]phenyl}benzamide | Human | 2913 | |
| BTK | Tec | TK | 4ot6 | A | | 4-(methylsulfonyl)-n-[3-(8-{[4-(morpholin-4-ylcarbonyl)phenyl]amino}imidazo[1,2-a]pyrazin-6-yl)phenyl]benzamide | Human | 2931 | |
| BTK | Tec | TK | 4otf | A | A | n-{3-[6-({4-[(2r)-1,4-dimethyl-3-oxopiperazin-2-yl]phenyl}amino)-4-methyl-5-oxo-4,5-dihydropyrazin-2-yl]-2-methylphenyl}-4,5,6,7-tetrahydro-1-benzothiophene-2-carboxamide | Human | 2901 | |
| BTK | Tec | TK | 4otf | A | B | n-{3-[6-({4-[(2r)-1,4-dimethyl-3-oxopiperazin-2-yl]phenyl}amino)-4-methyl-5-oxo-4,5-dihydropyrazin-2-yl]-2-methylphenyl}-4,5,6,7-tetrahydro-1-benzothiophene-2-carboxamide | Human | 2921 | |
| BTK | Tec | TK | 4otq | A | | 1-{5-[3-(7-tert-butyl-4-oxoquinazolin-3(4h)-yl)-2-methylphenyl]-1-methyl-2-oxo-1,2-dihydropyridin-3-yl}-3-methylurea | Human | 2895 | |
| BTK | Tec | TK | 4otr | A | | 6-cyclopropyl-2-[3-(5-{[5-(4-ethylpiperazin-1-yl)pyridin-2-yl]amino}-1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-2-(hydroxymethyl)phenyl]-8-fluoroisoquinolin-1(2h)-one | Human | 2896 | |
| BTK | Tec | TK | 4rfy | A | A | 6-(dimethylamino)-2-[2-(hydroxymethyl)-3-(1-methyl-5-{[5-(morpholin-4-ylcarbonyl)pyridin-2-yl]amino}-6-oxo-1,6-dihydropyridin-3-yl)phenyl]-3,4-dihydroisoquinolin-1(2h)-one | Human | 2935 | |
| BTK | Tec | TK | 4rfy | A | B | 6-(dimethylamino)-2-[2-(hydroxymethyl)-3-(1-methyl-5-{[5-(morpholin-4-ylcarbonyl)pyridin-2-yl]amino}-6-oxo-1,6-dihydropyridin-3-yl)phenyl]-3,4-dihydroisoquinolin-1(2h)-one | Human | 2933 | |
| BTK | Tec | TK | 4rfz | A | | 6-(dimethylamino)-8-fluoro-2-[2-(hydroxymethyl)-3-(1-methyl-5-{[5-(morpholin-4-ylcarbonyl)pyridin-2-yl]amino}-6-oxo-1,6-dihydropyridin-3-yl)phenyl]isoquinolin-1(2h)-one | Human | 2925 | |
| BTK | Tec | TK | 4rg0 | A | | 2-{8-fluoro-2-[2-(hydroxymethyl)-3-(1-methyl-5-{[5-(4-methylpiperazin-1-yl)pyridin-2-yl]amino}-6-oxo-1,6-dihydropyridin-3-yl)phenyl]-1-oxo-1,2,3,4-tetrahydroisoquinolin-6-yl}-2-methylpropanenitrile | Human | 2929 | |
| BTK | Tec | TK | 4rx5 | A | A | n-(6-fluoro-2-methyl-3-{5-[(5-methyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-2-yl)amino]-6-oxo-1,6-dihydropyridazin-3-yl}phenyl)-1-benzothiophene-2-carboxamide | Human | 6259 | |
| BTK | Tec | TK | 4rx5 | A | B | n-(6-fluoro-2-methyl-3-{5-[(5-methyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-2-yl)amino]-6-oxo-1,6-dihydropyridazin-3-yl}phenyl)-1-benzothiophene-2-carboxamide | Human | 6258 | |
| BTK | Tec | TK | 4yhf | A | A | (2s)-2-({(3r)-3-[4-amino-3-(4-phenoxyphenyl)-1h-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl}carbonyl)-4,4-dimethylpentanenitrile | Human | 2916 | |
| BTK | Tec | TK | 4yhf | A | B | (2s)-2-({(3r)-3-[4-amino-3-(4-phenoxyphenyl)-1h-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl}carbonyl)-4,4-dimethylpentanenitrile | Human | 2902 | |
| BTK | Tec | TK | 4yhf | B | A | (2s)-2-({(3r)-3-[4-amino-3-(4-phenoxyphenyl)-1h-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl}carbonyl)-4,4-dimethylpentanenitrile | Human | 2897 | |
| BTK | Tec | TK | 4yhf | B | B | (2s)-2-({(3r)-3-[4-amino-3-(4-phenoxyphenyl)-1h-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl}carbonyl)-4,4-dimethylpentanenitrile | Human | 2912 | |
| BTK | Tec | TK | 4z3v | A | A | 4-amino-8-(5-methyl-1h-indazol-6-yl)cinnoline-3-carboxamide | Human | 2934 | |
| BTK | Tec | TK | 4z3v | A | B | 4-amino-8-(5-methyl-1h-indazol-6-yl)cinnoline-3-carboxamide | Human | 2914 | |
| BTK | Tec | TK | 4zly | A | A | 4-aminocinnoline-3-carboxamide | Human | 2926 | |
| BTK | Tec | TK | 4zly | A | B | 4-aminocinnoline-3-carboxamide | Human | 2920 | |
| BTK | Tec | TK | 4zly | A | C | 4-aminocinnoline-3-carboxamide | Human | 2915 | |
| BTK | Tec | TK | 4zlz | A | A | 4-amino-8-(4-methylpyridin-3-yl)cinnoline-3-carboxamide | Human | 2923 | |
| BTK | Tec | TK | 4zlz | A | B | 4-amino-8-(4-methylpyridin-3-yl)cinnoline-3-carboxamide | Human | 2924 | |
| BTK | Tec | TK | 5bpy | A | | 6-{(3r)-3-[(4-tert-butylbenzoyl)amino]piperidin-1-yl}-2-{[4-(morpholin-4-ylcarbonyl)phenyl]amino}pyridine-3-carboxamide | Human | 6095 | |
| BTK | Tec | TK | 5bpy | B | | 6-{(3r)-3-[(4-tert-butylbenzoyl)amino]piperidin-1-yl}-2-{[4-(morpholin-4-ylcarbonyl)phenyl]amino}pyridine-3-carboxamide | Human | 6094 | |
| BTK | Tec | TK | 5bq0 | A | A | 4-(2-chlorophenyl)-7-[(4-methylpiperazin-1-yl)carbonyl]-9h-carbazole-1-carboxamide | Human | 6871 | |
| BTK | Tec | TK | 5bq0 | A | B | 4-(2-chlorophenyl)-7-[(4-methylpiperazin-1-yl)carbonyl]-9h-carbazole-1-carboxamide | Human | 6872 | |
| BTK | Tec | TK | 5fbn | C | A | 4-[8-azanyl-3-[(3~{r})-1-(3-methyloxetan-3-yl)carbonylpiperidin-3-yl]imidazo[1,5-a]pyrazin-1-yl]-~{n}-[4-(trifluoromethyl)pyridin-2-yl]benzamide | Human | 6381 | |
| BTK | Tec | TK | 5fbn | C | B | 4-[8-azanyl-3-[(3~{r})-1-(3-methyloxetan-3-yl)carbonylpiperidin-3-yl]imidazo[1,5-a]pyrazin-1-yl]-~{n}-[4-(trifluoromethyl)pyridin-2-yl]benzamide | Human | 6382 | |
| BTK | Tec | TK | 5fbn | D | A | 4-[8-azanyl-3-[(3~{r})-1-(3-methyloxetan-3-yl)carbonylpiperidin-3-yl]imidazo[1,5-a]pyrazin-1-yl]-~{n}-[4-(trifluoromethyl)pyridin-2-yl]benzamide | Human | 6384 | |
| BTK | Tec | TK | 5fbn | D | B | 4-[8-azanyl-3-[(3~{r})-1-(3-methyloxetan-3-yl)carbonylpiperidin-3-yl]imidazo[1,5-a]pyrazin-1-yl]-~{n}-[4-(trifluoromethyl)pyridin-2-yl]benzamide | Human | 6383 | |
| BTK | Tec | TK | 5fbo | A | A | 4-[8-azanyl-3-[(3~{r},6~{s})-1-cyclopropylcarbonyl-6-methyl-piperidin-3-yl]imidazo[1,5-a]pyrazin-1-yl]-3-fluoranyl-~{n}-[4-(trifluoromethyl)pyridin-2-yl]benzamide | Human | 6455 | |
| BTK | Tec | TK | 5fbo | A | B | 4-[8-azanyl-3-[(3~{r},6~{s})-1-cyclopropylcarbonyl-6-methyl-piperidin-3-yl]imidazo[1,5-a]pyrazin-1-yl]-3-fluoranyl-~{n}-[4-(trifluoromethyl)pyridin-2-yl]benzamide | Human | 6456 | |
| BTK | Tec | TK | 5j87 | A | A | n-[3-(5-{[3-(acryloylamino)-4-(morpholine-4-carbonyl)phenyl]amino}-1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-2-methylphenyl]-4-tert-butylbenzamide | Human | 8002 | |
| BTK | Tec | TK | 5j87 | A | B | n-[3-(5-{[3-(acryloylamino)-4-(morpholine-4-carbonyl)phenyl]amino}-1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-2-methylphenyl]-4-tert-butylbenzamide | Human | 8003 | |
| BTK | Tec | TK | 5j87 | B | A | n-[3-(5-{[3-(acryloylamino)-4-(morpholine-4-carbonyl)phenyl]amino}-1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-2-methylphenyl]-4-tert-butylbenzamide | Human | 8005 | |
| BTK | Tec | TK | 5j87 | B | B | n-[3-(5-{[3-(acryloylamino)-4-(morpholine-4-carbonyl)phenyl]amino}-1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-2-methylphenyl]-4-tert-butylbenzamide | Human | 8007 | |
| BTK | Tec | TK | 5j87 | C | A | n-[3-(5-{[3-(acryloylamino)-4-(morpholine-4-carbonyl)phenyl]amino}-1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-2-methylphenyl]-4-tert-butylbenzamide | Human | 8004 | |
| BTK | Tec | TK | 5j87 | C | B | n-[3-(5-{[3-(acryloylamino)-4-(morpholine-4-carbonyl)phenyl]amino}-1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-2-methylphenyl]-4-tert-butylbenzamide | Human | 8006 | |
| BTK | Tec | TK | 5j87 | D | A | n-[3-(5-{[3-(acryloylamino)-4-(morpholine-4-carbonyl)phenyl]amino}-1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-2-methylphenyl]-4-tert-butylbenzamide | Human | 8008 | |
| BTK | Tec | TK | 5j87 | D | B | n-[3-(5-{[3-(acryloylamino)-4-(morpholine-4-carbonyl)phenyl]amino}-1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-2-methylphenyl]-4-tert-butylbenzamide | Human | 8001 | |
| BTK | Tec | TK | 5jrs | A | | 4-[2-fluoro-3-(4-oxoquinazolin-3(4h)-yl)phenyl]-7-(2-hydroxypropan-2-yl)-9h-carbazole-1-carboxamide | Human | 7032 | |
| BTK | Tec | TK | 5jrs | B | | 4-[2-fluoro-3-(4-oxoquinazolin-3(4h)-yl)phenyl]-7-(2-hydroxypropan-2-yl)-9h-carbazole-1-carboxamide | Human | 7033 | |
| BTK | Tec | TK | 5kup | A | A | 6-~{tert}-butyl-8-fluoranyl-2-[3-(hydroxymethyl)-4-[1-methyl-6-oxidanylidene-5-(pyrimidin-4-ylamino)pyridin-3-yl]pyridin-2-yl]phthalazin-1-one | Human | 7051 | |
| BTK | Tec | TK | 5kup | A | B | 6-~{tert}-butyl-8-fluoranyl-2-[3-(hydroxymethyl)-4-[1-methyl-6-oxidanylidene-5-(pyrimidin-4-ylamino)pyridin-3-yl]pyridin-2-yl]phthalazin-1-one | Human | 7052 | |
| BTK | Tec | TK | 5p9f | A | A | n-{3-[6-({4-[(2r)-1,4-dimethyl-3-oxopiperazin-2-yl]phenyl}amino)-4-methyl-5-oxo-4,5-dihydropyrazin-2-yl]-2-methylphenyl}-4,5,6,7-tetrahydro-1-benzothiophene-2-carboxamide | Human | 7632 | |
| BTK | Tec | TK | 5p9f | A | B | n-{3-[6-({4-[(2r)-1,4-dimethyl-3-oxopiperazin-2-yl]phenyl}amino)-4-methyl-5-oxo-4,5-dihydropyrazin-2-yl]-2-methylphenyl}-4,5,6,7-tetrahydro-1-benzothiophene-2-carboxamide | Human | 7629 | |
| BTK | Tec | TK | 5p9g | A | A | 6-cyclopropyl-8-fluoranyl-2-[2-(hydroxymethyl)-3-[1-methyl-5-[[5-(4-methylpiperazin-1-yl)pyridin-2-yl]amino]-6-oxidanylidene-pyridin-3-yl]phenyl]isoquinolin-1-one | Human | 7635 | |
| BTK | Tec | TK | 5p9g | A | B | 6-cyclopropyl-8-fluoranyl-2-[2-(hydroxymethyl)-3-[1-methyl-5-[[5-(4-methylpiperazin-1-yl)pyridin-2-yl]amino]-6-oxidanylidene-pyridin-3-yl]phenyl]isoquinolin-1-one | Human | 7644 | |
| BTK | Tec | TK | 5p9h | A | A | 6-~{tert}-butyl-8-fluoranyl-2-[3-(hydroxymethyl)-4-[1-methyl-5-[[5-(1-methylpiperidin-4-yl)pyridin-2-yl]amino]-6-oxidanylidene-pyridazin-3-yl]pyridin-2-yl]phthalazin-1-one | Human | 7631 | |
| BTK | Tec | TK | 5p9h | A | B | 6-~{tert}-butyl-8-fluoranyl-2-[3-(hydroxymethyl)-4-[1-methyl-5-[[5-(1-methylpiperidin-4-yl)pyridin-2-yl]amino]-6-oxidanylidene-pyridazin-3-yl]pyridin-2-yl]phthalazin-1-one | Human | 7643 | |
| BTK | Tec | TK | 5p9i | A | A | 1-{(3r)-3-[4-amino-3-(4-phenoxyphenyl)-1h-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl}prop-2-en-1-one | Human | 7627 | |
| BTK | Tec | TK | 5p9i | A | B | 1-{(3r)-3-[4-amino-3-(4-phenoxyphenyl)-1h-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl}prop-2-en-1-one | Human | 7642 | |
| BTK | Tec | TK | 5p9i | A | C | 1-{(3r)-3-[4-amino-3-(4-phenoxyphenyl)-1h-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl}prop-2-en-1-one | Human | 7638 | |
| BTK | Tec | TK | 5p9j | A | A | 1-[(3~{r})-3-[4-azanyl-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]propan-1-one | Human | 7637 | |
| BTK | Tec | TK | 5p9j | A | B | 1-[(3~{r})-3-[4-azanyl-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]propan-1-one | Human | 7628 | |
| BTK | Tec | TK | 5p9j | A | C | 1-[(3~{r})-3-[4-azanyl-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]propan-1-one | Human | 7640 | |
| BTK | Tec | TK | 5p9k | A | A | 4-[4-[[5-fluoranyl-4-[[3-(propanoylamino)phenyl]amino]pyrimidin-2-yl]amino]phenoxy]-~{n}-methyl-pyridine-2-carboxamide | Human | 7633 | |
| BTK | Tec | TK | 5p9k | A | B | 4-[4-[[5-fluoranyl-4-[[3-(propanoylamino)phenyl]amino]pyrimidin-2-yl]amino]phenoxy]-~{n}-methyl-pyridine-2-carboxamide | Human | 7636 | |
| BTK | Tec | TK | 5p9k | A | C | 4-[4-[[5-fluoranyl-4-[[3-(propanoylamino)phenyl]amino]pyrimidin-2-yl]amino]phenoxy]-~{n}-methyl-pyridine-2-carboxamide | Human | 7626 | |
| BTK | Tec | TK | 5p9l | A | A | ~{n}-[3-[[5-fluoranyl-2-[[4-(2-methoxyethoxy)phenyl]amino]pyrimidin-4-yl]amino]phenyl]propanamide | Human | 7625 | |
| BTK | Tec | TK | 5p9l | A | B | ~{n}-[3-[[5-fluoranyl-2-[[4-(2-methoxyethoxy)phenyl]amino]pyrimidin-4-yl]amino]phenyl]propanamide | Human | 7630 | |
| BTK | Tec | TK | 5p9m | A | A | 6-azanyl-9-[(3~{r})-1-[(~{e})-but-2-enoyl]pyrrolidin-3-yl]-7-(4-phenoxyphenyl)purin-8-one | Human | 7634 | |
| BTK | Tec | TK | 5p9m | A | B | 6-azanyl-9-[(3~{r})-1-[(~{e})-but-2-enoyl]pyrrolidin-3-yl]-7-(4-phenoxyphenyl)purin-8-one | Human | 7639 | |
| BTK | Tec | TK | 5p9m | A | C | 6-azanyl-9-[(3~{r})-1-[(~{e})-but-2-enoyl]pyrrolidin-3-yl]-7-(4-phenoxyphenyl)purin-8-one | Human | 7641 | |
| BTK | Tec | TK | 5t18 | A | A | 6-fluoro-5-(r)-(3-(s)-(8-fluoro-1-methyl-2,4-dioxo-1,2-dihydroquinazolin-3(4h)-yl)-2-methylphenyl)-2-(s)-(2-hydroxypropan-2-yl)-2,3,4,9-tetrahydro-1h-carbazole-8-carboxamide | Human | 7508 | |
| BTK | Tec | TK | 5t18 | A | B | 6-fluoro-5-(r)-(3-(s)-(8-fluoro-1-methyl-2,4-dioxo-1,2-dihydroquinazolin-3(4h)-yl)-2-methylphenyl)-2-(s)-(2-hydroxypropan-2-yl)-2,3,4,9-tetrahydro-1h-carbazole-8-carboxamide | Human | 7507 | |
| BTK | Tec | TK | 5u9d | A | A | (r)-n-methyl-2-(3-((quinoxalin-6-ylamino)methyl)furan-2-carbonyl)-2,3,4,9-tetrahydro-1h-pyrido[3,4-b]indole-3-carboxamide | Human | 7393 | |
| BTK | Tec | TK | 5u9d | A | B | (r)-n-methyl-2-(3-((quinoxalin-6-ylamino)methyl)furan-2-carbonyl)-2,3,4,9-tetrahydro-1h-pyrido[3,4-b]indole-3-carboxamide | Human | 7392 | |
| BTK | Tec | TK | 5vfi | A | A | 2-[3'-(hydroxymethyl)-1-methyl-5-({5-[(2s)-2-methyl-4-(oxetan-3-yl)piperazin-1-yl]pyridin-2-yl}amino)-6-oxo[1,6-dihydro[3,4'-bipyridine]]-2'-yl]-7,7-dimethyl-3,4,7,8-tetrahydro-2h-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-1(6h)-one | Human | 9602 | |
| BTK | Tec | TK | 5vfi | A | B | 2-[3'-(hydroxymethyl)-1-methyl-5-({5-[(2s)-2-methyl-4-(oxetan-3-yl)piperazin-1-yl]pyridin-2-yl}amino)-6-oxo[1,6-dihydro[3,4'-bipyridine]]-2'-yl]-7,7-dimethyl-3,4,7,8-tetrahydro-2h-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-1(6h)-one | Human | 9601 | |
| BTK | Tec | TK | 5vgo | A | A | 2-(2-methoxyethoxy)ethanol | Human | 8218 | |
| BTK | Tec | TK | 5vgo | A | B | 2-(2-methoxyethoxy)ethanol | Human | 8219 | |
| BTK | Tec | TK | 5xyz | A | A | n-[3-(5-{[(2-chloro-6-fluorophenyl)methyl]amino}-1h-1,2,4-triazol-3-yl)phenyl]propanamide | Human | 9929 | |
| BTK | Tec | TK | 5xyz | A | B | n-[3-(5-{[(2-chloro-6-fluorophenyl)methyl]amino}-1h-1,2,4-triazol-3-yl)phenyl]propanamide | Human | 9932 | |
| BTK | Tec | TK | 5xyz | B | A | n-[3-(5-{[(2-chloro-6-fluorophenyl)methyl]amino}-1h-1,2,4-triazol-3-yl)phenyl]propanamide | Human | 9931 | |
| BTK | Tec | TK | 5xyz | B | B | n-[3-(5-{[(2-chloro-6-fluorophenyl)methyl]amino}-1h-1,2,4-triazol-3-yl)phenyl]propanamide | Human | 9930 | |
| BTK | Tec | TK | 5zz4 | A | | n-[3-(4-amino-6-{[4-(morpholine-4-carbonyl)phenyl]amino}-1,3,5-triazin-2-yl)-2-methylphenyl]-4-tert-butylbenzamide | Human | 10479 | |
| BTK | Tec | TK | 5zz4 | B | | n-[3-(4-amino-6-{[4-(morpholine-4-carbonyl)phenyl]amino}-1,3,5-triazin-2-yl)-2-methylphenyl]-4-tert-butylbenzamide | Human | 10468 | |
| BTK | Tec | TK | 5zz4 | C | | n-[3-(4-amino-6-{[4-(morpholine-4-carbonyl)phenyl]amino}-1,3,5-triazin-2-yl)-2-methylphenyl]-4-tert-butylbenzamide | Human | 10464 | |
| BTK | Tec | TK | 5zz4 | D | | n-[3-(4-amino-6-{[4-(morpholine-4-carbonyl)phenyl]amino}-1,3,5-triazin-2-yl)-2-methylphenyl]-4-tert-butylbenzamide | Human | 10478 | |
| BTK | Tec | TK | 5zz4 | E | | n-[3-(4-amino-6-{[4-(morpholine-4-carbonyl)phenyl]amino}-1,3,5-triazin-2-yl)-2-methylphenyl]-4-tert-butylbenzamide | Human | 10470 | |
| BTK | Tec | TK | 5zz4 | F | | n-[3-(4-amino-6-{[4-(morpholine-4-carbonyl)phenyl]amino}-1,3,5-triazin-2-yl)-2-methylphenyl]-4-tert-butylbenzamide | Human | 10469 | |
| BTK | Tec | TK | 6aua | A | A | n-{3-[(2r)-6-{[3-amino-4-(morpholine-4-carbonyl)phenyl]amino}-5-oxo-2,5-dihydropyrazin-2-yl]-2-methylphenyl}-4-(piperidin-1-yl)benzamide | Human | 10472 | |
| BTK | Tec | TK | 6aua | A | B | n-{3-[(2r)-6-{[3-amino-4-(morpholine-4-carbonyl)phenyl]amino}-5-oxo-2,5-dihydropyrazin-2-yl]-2-methylphenyl}-4-(piperidin-1-yl)benzamide | Human | 10473 | |
| BTK | Tec | TK | 6aub | A | A | 4-tert-butyl-n-[2-methyl-3-(1-methyl-5-{[5-(morpholine-4-carbonyl)pyridin-2-yl]amino}-6-oxo-1,6-dihydropyridin-3-yl)phenyl]benzamide | Human | 10466 | |
| BTK | Tec | TK | 6aub | A | B | 4-tert-butyl-n-[2-methyl-3-(1-methyl-5-{[5-(morpholine-4-carbonyl)pyridin-2-yl]amino}-6-oxo-1,6-dihydropyridin-3-yl)phenyl]benzamide | Human | 10475 | |
| BTK | Tec | TK | 6bik | A | A | 4-tert-butyl-n-[2-(hydroxymethyl)-3-(1-methyl-5-{[5-(morpholine-4-carbonyl)pyridin-2-yl]amino}-6-oxo-1,6-dihydropyridazin-3-yl)phenyl]benzamide | Human | 10680 | |
| BTK | Tec | TK | 6bik | A | B | 4-tert-butyl-n-[2-(hydroxymethyl)-3-(1-methyl-5-{[5-(morpholine-4-carbonyl)pyridin-2-yl]amino}-6-oxo-1,6-dihydropyridazin-3-yl)phenyl]benzamide | Human | 10678 | |
| BTK | Tec | TK | 6bke | A | A | n-[2-(2-hydroxyethyl)-3-{5-[(5-methyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-2-yl)amino]-6-oxo-1,6-dihydropyridazin-3-yl}phenyl]-1-benzothiophene-2-carboxamide | Human | 10681 | |
| BTK | Tec | TK | 6bke | A | B | n-[2-(2-hydroxyethyl)-3-{5-[(5-methyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-2-yl)amino]-6-oxo-1,6-dihydropyridazin-3-yl}phenyl]-1-benzothiophene-2-carboxamide | Human | 10683 | |
| BTK | Tec | TK | 6bkh | A | A | n-[2-(hydroxymethyl)-3-{5-[(5-methyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-2-yl)amino]-6-oxo-1,6-dihydropyridazin-3-yl}phenyl]-1-benzothiophene-2-carboxamide | Human | 10682 | |
| BTK | Tec | TK | 6bkh | A | B | n-[2-(hydroxymethyl)-3-{5-[(5-methyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-2-yl)amino]-6-oxo-1,6-dihydropyridazin-3-yl}phenyl]-1-benzothiophene-2-carboxamide | Human | 10677 | |
| BTK | Tec | TK | 6bkw | A | A | n-(3-{5-[(1,5-dimethyl-1h-pyrazol-3-yl)amino]-1-methyl-6-oxo-1,6-dihydropyridazin-3-yl}-2,6-difluorophenyl)-4,5,6,7-tetrahydro-1-benzothiophene-2-carboxamide | Human | 10686 | |
| BTK | Tec | TK | 6bkw | A | B | n-(3-{5-[(1,5-dimethyl-1h-pyrazol-3-yl)amino]-1-methyl-6-oxo-1,6-dihydropyridazin-3-yl}-2,6-difluorophenyl)-4,5,6,7-tetrahydro-1-benzothiophene-2-carboxamide | Human | 10679 | |
| BTK | Tec | TK | 6bln | A | A | n-(3-{5-[(1,5-dimethyl-1h-pyrazol-3-yl)amino]-6-oxo-1,6-dihydropyridazin-3-yl}-2,6-difluorophenyl)-4,5,6,7-tetrahydro-1-benzothiophene-2-carboxamide | Human | 10685 | |
| BTK | Tec | TK | 6bln | A | B | n-(3-{5-[(1,5-dimethyl-1h-pyrazol-3-yl)amino]-6-oxo-1,6-dihydropyridazin-3-yl}-2,6-difluorophenyl)-4,5,6,7-tetrahydro-1-benzothiophene-2-carboxamide | Human | 10684 | |
| BTK | Tec | TK | 6di0 | A | A | 6-(cyclohexylamino)pyridine-3-carboxamide | Human | 10629 | |
| BTK | Tec | TK | 6di0 | A | B | 6-(cyclohexylamino)pyridine-3-carboxamide | Human | 10626 | |
| BTK | Tec | TK | 6di0 | A | C | 6-(cyclohexylamino)pyridine-3-carboxamide | Human | 10628 | |
| BTK | Tec | TK | 6di1 | A | A | 4-amino-2-[(3s)-3-(propanoylamino)pyrrolidin-1-yl]pyrimidine-5-carboxamide | Human | 10630 | |
| BTK | Tec | TK | 6di1 | A | B | 4-amino-2-[(3s)-3-(propanoylamino)pyrrolidin-1-yl]pyrimidine-5-carboxamide | Human | 10627 | |
| BTK | Tec | TK | 6di3 | A | | 6-[(3s)-3-(acryloylamino)pyrrolidin-1-yl]-2-(4-phenoxyphenoxy)pyridine-3-carboxamide | Human | 10474 | |
| BTK | Tec | TK | 6di5 | A | A | 2-(4-phenoxyphenoxy)-6-[(1s,4s)-5-propanoyl-2,5-diazabicyclo[2.2.1]heptan-2-yl]pyridine-3-carboxamide | Human | 10471 | |
| BTK | Tec | TK | 6di5 | A | B | 2-(4-phenoxyphenoxy)-6-[(1s,4s)-5-propanoyl-2,5-diazabicyclo[2.2.1]heptan-2-yl]pyridine-3-carboxamide | Human | 10481 | |
| BTK | Tec | TK | 6di9 | A | A | 6-[(3s)-3-(acryloylamino)pyrrolidin-1-yl]-2-{[4-(tert-butylcarbamoyl)phenyl]amino}pyridine-3-carboxamide | Human | 10465 | |
| BTK | Tec | TK | 6di9 | A | B | 6-[(3s)-3-(acryloylamino)pyrrolidin-1-yl]-2-{[4-(tert-butylcarbamoyl)phenyl]amino}pyridine-3-carboxamide | Human | 10476 | |
| BTK | Tec | TK | 6e4f | A | A | 1,5-anhydro-2-{[5-(2-chloro-4-phenoxybenzene-1-carbonyl)-7h-pyrrolo[2,3-d]pyrimidin-4-yl]amino}-2,3,4-trideoxy-d-erythro-hexitol | Human | 10477 | |
| BTK | Tec | TK | 6e4f | A | B | 1,5-anhydro-2-{[5-(2-chloro-4-phenoxybenzene-1-carbonyl)-7h-pyrrolo[2,3-d]pyrimidin-4-yl]amino}-2,3,4-trideoxy-d-erythro-hexitol | Human | 10480 | |
| BTK | Tec | TK | 6ep9 | A | | n-[2-methyl-3-[4-methyl-6-[4-(4-methylpiperazine-1-carbonyl)anilino]-5-oxo-pyrazin-2-yl]phenyl]-4-(1-piperidyl)benzamide | Human | 10467 | |
| BTK | Tec | TK | 6hrp | A | | 6-~{tert}-butyl-8-fluoranyl-2-[2-(hydroxymethyl)-3-[1-methyl-5-[(5-morpholin-4-ylcarbonylpyridin-2-yl)amino]-6-oxidanylidene-pyridazin-3-yl]phenyl]phthalazin-1-one | Human | 10971 | |
| BTK | Tec | TK | 6hrt | A | | (9~{s})-12-(6-~{tert}-butyl-8-fluoranyl-1-oxidanylidene-phthalazin-2-yl)-6-methyl-4-[(5-morpholin-4-ylcarbonylpyridin-2-yl)amino]-9-oxidanyl-6-azatricyclo[9.4.0.0^{2,7}]pentadeca-1(15),2(7),3,11,13-pentaen-5-one | Human | 10972 | |
| BTK | Tec | TK | 6j6m | A | A | (7s)-2-(4-phenoxyphenyl)-7-(1-propanoylpiperidin-4-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | 11767 | |
| BTK | Tec | TK | 6j6m | A | B | (7s)-2-(4-phenoxyphenyl)-7-(1-propanoylpiperidin-4-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | 11766 | |
| BTK | Tec | TK | 6n9p | A | A | n-(3-{[2-amino-3-(4-phenoxyphenyl)pyridin-4-yl]oxy}phenyl)propanamide | Human | 10886 | |
| BTK | Tec | TK | 6n9p | A | B | n-(3-{[2-amino-3-(4-phenoxyphenyl)pyridin-4-yl]oxy}phenyl)propanamide | Human | 10887 | |
| BTK | Tec | TK | 6n9p | A | C | n-(3-{[2-amino-3-(4-phenoxyphenyl)pyridin-4-yl]oxy}phenyl)propanamide | Human | 10888 | |
| BTK | Tec | TK | 6nfh | A | A | 8-(2,3-dihydro-1h-inden-5-yl)-2-({4-[(2s)-3-(dimethylamino)-2-hydroxypropoxy]phenyl}amino)-5,8-dihydropteridine-6,7-dione | Human | 10964 | |
| BTK | Tec | TK | 6nfh | A | B | 8-(2,3-dihydro-1h-inden-5-yl)-2-({4-[(2s)-3-(dimethylamino)-2-hydroxypropoxy]phenyl}amino)-5,8-dihydropteridine-6,7-dione | Human | 10965 | |
| BTK | Tec | TK | 6nfi | A | A | n-(3-{[(2,6-dimethylphenyl)methyl]amino}-7-methoxyindeno[1,2-c]pyrazol-6-yl)methanesulfonamide | Human | 10962 | |
| BTK | Tec | TK | 6nfi | A | B | n-(3-{[(2,6-dimethylphenyl)methyl]amino}-7-methoxyindeno[1,2-c]pyrazol-6-yl)methanesulfonamide | Human | 10963 | |
| BTK | Tec | TK | 6nzm | A | A | n-[2-fluoro-6-(pyrrolidin-1-yl)phenyl]-n'-{3-[(2r)-1-(2-hydroxyethyl)-4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)piperazin-2-yl]phenyl}urea | Human | 11144 | |
| BTK | Tec | TK | 6nzm | A | B | n-[2-fluoro-6-(pyrrolidin-1-yl)phenyl]-n'-{3-[(2r)-1-(2-hydroxyethyl)-4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)piperazin-2-yl]phenyl}urea | Human | 11143 | |
| BTK | Tec | TK | 6nzm | D | A | n-[2-fluoro-6-(pyrrolidin-1-yl)phenyl]-n'-{3-[(2r)-1-(2-hydroxyethyl)-4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)piperazin-2-yl]phenyl}urea | Human | 11141 | |
| BTK | Tec | TK | 6nzm | D | B | n-[2-fluoro-6-(pyrrolidin-1-yl)phenyl]-n'-{3-[(2r)-1-(2-hydroxyethyl)-4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)piperazin-2-yl]phenyl}urea | Human | 11142 | |
| BTK | Tec | TK | 6o8i | A | A | 4-[(3s)-3-{[(2e)-but-2-enoyl]amino}piperidin-1-yl]-5-fluoro-2,3-dimethyl-1h-indole-7-carboxamide | Human | 11002 | |
| BTK | Tec | TK | 6o8i | A | B | 4-[(3s)-3-{[(2e)-but-2-enoyl]amino}piperidin-1-yl]-5-fluoro-2,3-dimethyl-1h-indole-7-carboxamide | Human | 11001 | |
| BTK | Tec | TK | 6omu | A | A | 1-[4-({[6-amino-5-(4-phenoxyphenyl)pyrimidin-4-yl]amino}methyl)piperidin-1-yl]prop-2-en-1-one | Human | 11529 | |
| BTK | Tec | TK | 6omu | A | B | 1-[4-({[6-amino-5-(4-phenoxyphenyl)pyrimidin-4-yl]amino}methyl)piperidin-1-yl]prop-2-en-1-one | Human | 11530 | |
| BTK | Tec | TK | 6omu | A | C | - | Human | 11528 | |
| BTK | Tec | TK | 6s90 | A | | 4-~{tert}-butyl-~{n}-[2-methyl-3-[6-[4-(4-methylpiperazin-1-yl)carbonylphenyl]-7~{h}-pyrrolo[2,3-d]pyrimidin-4-yl]phenyl]benzamide | Human | 11636 | |
| BTK | Tec | TK | 6s90 | B | | 4-~{tert}-butyl-~{n}-[2-methyl-3-[6-[4-(4-methylpiperazin-1-yl)carbonylphenyl]-7~{h}-pyrrolo[2,3-d]pyrimidin-4-yl]phenyl]benzamide | Human | 11635 | |
| BTK | Tec | TK | 6tfp | A | | ~{n}-[3-[6-azanyl-5-[2-[methyl(propanoyl)amino]ethoxy]pyrimidin-4-yl]-5-fluoranyl-2-methyl-phenyl]-4-cyclopropyl-2-fluoranyl-benzamide | Human | 12024 | |
| BTK | Tec | TK | 6tfp | B | | ~{n}-[3-[6-azanyl-5-[2-[methyl(propanoyl)amino]ethoxy]pyrimidin-4-yl]-5-fluoranyl-2-methyl-phenyl]-4-cyclopropyl-2-fluoranyl-benzamide | Human | 12020 | |
| BTK | Tec | TK | 6tfp | C | | ~{n}-[3-[6-azanyl-5-[2-[methyl(propanoyl)amino]ethoxy]pyrimidin-4-yl]-5-fluoranyl-2-methyl-phenyl]-4-cyclopropyl-2-fluoranyl-benzamide | Human | 12023 | |
| BTK | Tec | TK | 6tfp | D | | ~{n}-[3-[6-azanyl-5-[2-[methyl(propanoyl)amino]ethoxy]pyrimidin-4-yl]-5-fluoranyl-2-methyl-phenyl]-4-cyclopropyl-2-fluoranyl-benzamide | Human | 12021 | |
| BTK | Tec | TK | 6tfp | E | | ~{n}-[3-[6-azanyl-5-[2-[methyl(propanoyl)amino]ethoxy]pyrimidin-4-yl]-5-fluoranyl-2-methyl-phenyl]-4-cyclopropyl-2-fluoranyl-benzamide | Human | 12022 | |
| BTK | Tec | TK | 6vxq | A | A | n-{[4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl]methyl}benzamide | Human | 13100 | |
| BTK | Tec | TK | 6vxq | A | B | n-{[4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl]methyl}benzamide | Human | 13101 | |
| BTK | Tec | TK | 6w06 | A | A | 4-~{tert}-butyl-~{n}-[[4-(7~{h}-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl]methyl]benzamide | Human | 13099 | |
| BTK | Tec | TK | 6w06 | A | B | 4-~{tert}-butyl-~{n}-[[4-(7~{h}-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl]methyl]benzamide | Human | 13098 | |
| BTK | Tec | TK | 6w07 | A | A | ~{n}-[[2-methyl-4-[2-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]phenyl]methyl]-3-propan-2-yloxy-azetidine-1-carboxamide | Human | 13096 | |
| BTK | Tec | TK | 6w07 | A | B | ~{n}-[[2-methyl-4-[2-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]phenyl]methyl]-3-propan-2-yloxy-azetidine-1-carboxamide | Human | 13102 | |
| BTK | Tec | TK | 6w07 | A | C | ~{n}-[[2-methyl-4-[2-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]phenyl]methyl]-3-propan-2-yloxy-azetidine-1-carboxamide | Human | 13097 | |
| BTK | Tec | TK | 6w7o | A | | [5-({[(3s)-2-(n-methyl-l-alanyl-3-methyl-l-valyl)-3-{[(1r)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl}-1,2,3,4-tetrahydroisoquinolin-7-yl]oxy}methyl)pyrazin-2-yl]methyl (3r)-3-{5-amino-4-carbamoyl-3-[4-(2,4-difluorophenoxy)phenyl]-1h-pyrazol-1-yl}piperidine-1-carboxylate | Human | 13195 | |
| BTK | Tec | TK | 6w7o | B | | [5-({[(3s)-2-(n-methyl-l-alanyl-3-methyl-l-valyl)-3-{[(1r)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl}-1,2,3,4-tetrahydroisoquinolin-7-yl]oxy}methyl)pyrazin-2-yl]methyl (3r)-3-{5-amino-4-carbamoyl-3-[4-(2,4-difluorophenoxy)phenyl]-1h-pyrazol-1-yl}piperidine-1-carboxylate | Human | 13196 | |
| BTK | Tec | TK | 6w8i | A | | - | Human | 12990 | |
| BTK | Tec | TK | 6w8i | B | | - | Human | 12991 | |
| BTK | Tec | TK | 6x3n | A | A | 4-{8-amino-3-[(6r,8as)-3-oxohexahydro-3h-[1,3]oxazolo[3,4-a]pyridin-6-yl]imidazo[1,5-a]pyrazin-1-yl}-n-[4-(trifluoromethyl)pyridin-2-yl]benzamide | Human | 12514 | |
| BTK | Tec | TK | 6x3n | A | B | 4-{8-amino-3-[(6r,8as)-3-oxohexahydro-3h-[1,3]oxazolo[3,4-a]pyridin-6-yl]imidazo[1,5-a]pyrazin-1-yl}-n-[4-(trifluoromethyl)pyridin-2-yl]benzamide | Human | 12510 | |
| BTK | Tec | TK | 6x3o | A | A | 4-{8-amino-3-[(6r,8as)-3-oxo-3,5,6,7,8,8a-hexahydroindolizin-6-yl]imidazo[1,5-a]pyrazin-1-yl}-3-methoxy-n-[4-(trifluoromethyl)pyridin-2-yl]benzamide | Human | 12513 | |
| BTK | Tec | TK | 6x3o | A | B | 4-{8-amino-3-[(6r,8as)-3-oxo-3,5,6,7,8,8a-hexahydroindolizin-6-yl]imidazo[1,5-a]pyrazin-1-yl}-3-methoxy-n-[4-(trifluoromethyl)pyridin-2-yl]benzamide | Human | 12512 | |
| BTK | Tec | TK | 6x3o | B | A | 4-{8-amino-3-[(6r,8as)-3-oxo-3,5,6,7,8,8a-hexahydroindolizin-6-yl]imidazo[1,5-a]pyrazin-1-yl}-3-methoxy-n-[4-(trifluoromethyl)pyridin-2-yl]benzamide | Human | 12508 | |
| BTK | Tec | TK | 6x3o | B | B | 4-{8-amino-3-[(6r,8as)-3-oxo-3,5,6,7,8,8a-hexahydroindolizin-6-yl]imidazo[1,5-a]pyrazin-1-yl}-3-methoxy-n-[4-(trifluoromethyl)pyridin-2-yl]benzamide | Human | 12511 | |
| BTK | Tec | TK | 6x3p | A | A | 4-{8-amino-3-[(6r,8as)-3-oxooctahydroindolizin-6-yl]imidazo[1,5-a]pyrazin-1-yl}-3-(cyclopropyloxy)-n-[4-(trifluoromethyl)pyridin-2-yl]benzamide | Human | 12516 | |
| BTK | Tec | TK | 6x3p | A | B | 4-{8-amino-3-[(6r,8as)-3-oxooctahydroindolizin-6-yl]imidazo[1,5-a]pyrazin-1-yl}-3-(cyclopropyloxy)-n-[4-(trifluoromethyl)pyridin-2-yl]benzamide | Human | 12517 | |
| BTK | Tec | TK | 6xe4 | A | A | (1s,2s)-n-[2'-(6-tert-butyl-8-fluoro-1-oxophthalazin-2(1h)-yl)-3'-(hydroxymethyl)-1-methyl-6-oxo[1,6-dihydro[3,4'-bipyridine]]-5-yl]-2-fluorocyclopropane-1-carboxamide | Human | 12515 | |
| BTK | Tec | TK | 6xe4 | A | B | (1s,2s)-n-[2'-(6-tert-butyl-8-fluoro-1-oxophthalazin-2(1h)-yl)-3'-(hydroxymethyl)-1-methyl-6-oxo[1,6-dihydro[3,4'-bipyridine]]-5-yl]-2-fluorocyclopropane-1-carboxamide | Human | 12509 | |
| BTK | Tec | TK | 7kxl | A | A | 3-tert-butyl-n-({2-fluoro-4-[2-(1-methyl-1h-pyrazol-4-yl)-1h-imidazo[4,5-b]pyridin-7-yl]phenyl}methyl)-1,2,4-oxadiazole-5-carboxamide | Human | 13563 | |
| BTK | Tec | TK | 7kxl | A | B | 3-tert-butyl-n-({2-fluoro-4-[2-(1-methyl-1h-pyrazol-4-yl)-1h-imidazo[4,5-b]pyridin-7-yl]phenyl}methyl)-1,2,4-oxadiazole-5-carboxamide | Human | 13561 | |
| BTK | Tec | TK | 7kxl | A | C | 3-tert-butyl-n-({2-fluoro-4-[2-(1-methyl-1h-pyrazol-4-yl)-1h-imidazo[4,5-b]pyridin-7-yl]phenyl}methyl)-1,2,4-oxadiazole-5-carboxamide | Human | 13576 | |
| BTK | Tec | TK | 7kxm | A | A | 4-tert-butyl-n-(2-methyl-3-{2-[4-(morpholine-4-carbonyl)phenyl]-1h-imidazo[4,5-b]pyridin-7-yl}phenyl)benzamide | Human | 13569 | |
| BTK | Tec | TK | 7kxm | A | B | 4-tert-butyl-n-(2-methyl-3-{2-[4-(morpholine-4-carbonyl)phenyl]-1h-imidazo[4,5-b]pyridin-7-yl}phenyl)benzamide | Human | 13564 | |
| BTK | Tec | TK | 7kxm | A | C | 4-tert-butyl-n-(2-methyl-3-{2-[4-(morpholine-4-carbonyl)phenyl]-1h-imidazo[4,5-b]pyridin-7-yl}phenyl)benzamide | Human | 13567 | |
| BTK | Tec | TK | 7kxn | A | A | 3-tert-butyl-n-[(1s)-6-{2-[5-methyl-1-(propan-2-yl)-1h-pyrazol-4-yl]-1h-imidazo[4,5-b]pyridin-7-yl}-1,2,3,4-tetrahydronaphthalen-1-yl]-1,2,4-oxadiazole-5-carboxamide | Human | 13574 | |
| BTK | Tec | TK | 7kxn | A | B | 3-tert-butyl-n-[(1s)-6-{2-[5-methyl-1-(propan-2-yl)-1h-pyrazol-4-yl]-1h-imidazo[4,5-b]pyridin-7-yl}-1,2,3,4-tetrahydronaphthalen-1-yl]-1,2,4-oxadiazole-5-carboxamide | Human | 13571 | |
| BTK | Tec | TK | 7kxn | A | C | 3-tert-butyl-n-[(1s)-6-{2-[5-methyl-1-(propan-2-yl)-1h-pyrazol-4-yl]-1h-imidazo[4,5-b]pyridin-7-yl}-1,2,3,4-tetrahydronaphthalen-1-yl]-1,2,4-oxadiazole-5-carboxamide | Human | 13570 | |
| BTK | Tec | TK | 7kxo | A | A | 3-tert-butyl-n-[(1r)-6-{2-[5-methyl-1-(oxan-4-yl)-1h-pyrazol-4-yl]-3h-imidazo[4,5-b]pyridin-7-yl}-1,2,3,4-tetrahydronaphthalen-1-yl]-1,2,4-oxadiazole-5-carboxamide | Human | 13573 | |
| BTK | Tec | TK | 7kxo | A | B | 3-tert-butyl-n-[(1r)-6-{2-[5-methyl-1-(oxan-4-yl)-1h-pyrazol-4-yl]-3h-imidazo[4,5-b]pyridin-7-yl}-1,2,3,4-tetrahydronaphthalen-1-yl]-1,2,4-oxadiazole-5-carboxamide | Human | 13568 | |
| BTK | Tec | TK | 7kxo | A | C | 3-tert-butyl-n-[(1r)-6-{2-[5-methyl-1-(oxan-4-yl)-1h-pyrazol-4-yl]-3h-imidazo[4,5-b]pyridin-7-yl}-1,2,3,4-tetrahydronaphthalen-1-yl]-1,2,4-oxadiazole-5-carboxamide | Human | 13572 | |
| BTK | Tec | TK | 7kxp | A | A | 3-tert-butyl-n-[(1s)-6-{2-[3-methyl-1-(oxan-4-yl)-1h-pyrazol-4-yl]-1h-imidazo[4,5-b]pyridin-7-yl}-1,2,3,4-tetrahydronaphthalen-1-yl]-1,2,4-oxadiazole-5-carboxamide | Human | 13575 | |
| BTK | Tec | TK | 7kxp | A | B | 3-tert-butyl-n-[(1s)-6-{2-[3-methyl-1-(oxan-4-yl)-1h-pyrazol-4-yl]-1h-imidazo[4,5-b]pyridin-7-yl}-1,2,3,4-tetrahydronaphthalen-1-yl]-1,2,4-oxadiazole-5-carboxamide | Human | 13566 | |
| BTK | Tec | TK | 7kxq | A | A | 3-tert-butyl-n-[(5r)-2-{2-[3,5-dimethyl-1-(propan-2-yl)-1h-pyrazol-4-yl]-3h-imidazo[4,5-b]pyridin-7-yl}-6,7,8,9-tetrahydro-5h-benzo[7]annulen-5-yl]-1,2,4-oxadiazole-5-carboxamide | Human | 13562 | |
| BTK | Tec | TK | 7kxq | A | B | 3-tert-butyl-n-[(5r)-2-{2-[3,5-dimethyl-1-(propan-2-yl)-1h-pyrazol-4-yl]-3h-imidazo[4,5-b]pyridin-7-yl}-6,7,8,9-tetrahydro-5h-benzo[7]annulen-5-yl]-1,2,4-oxadiazole-5-carboxamide | Human | 13565 | |
| BTK | Tec | TK | 7l5o | A | A | (2e)-2-{(3r)-3-[4-amino-3-(2-fluoro-4-phenoxyphenyl)-1h-pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl}-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile | Human | 14272 | |
| BTK | Tec | TK | 7l5o | A | B | (2e)-2-{(3r)-3-[4-amino-3-(2-fluoro-4-phenoxyphenyl)-1h-pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl}-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile | Human | 14271 | |
| BTK | Tec | TK | 7l5o | A | C | (2e)-2-{(3r)-3-[4-amino-3-(2-fluoro-4-phenoxyphenyl)-1h-pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl}-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile | Human | 14268 | |
| BTK | Tec | TK | 7l5p | A | A | (2e)-2-{(3r)-3-[4-amino-3-(2-fluoro-4-phenoxyphenyl)-1h-pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl}-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile | Human | 14269 | |
| BTK | Tec | TK | 7l5p | A | B | (2e)-2-{(3r)-3-[4-amino-3-(2-fluoro-4-phenoxyphenyl)-1h-pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl}-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile | Human | 14270 | |
| BTK | Tec | TK | 7lty | A | A | ~{n}-[(5~{r})-2-[2-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]-6,7,8,9-tetrahydro-5~{h}-benzo[7]annulen-5-yl]-3-propan-2-yloxy-azetidine-1-carboxamide | Human | 14065 | |
| BTK | Tec | TK | 7lty | A | B | ~{n}-[(5~{r})-2-[2-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]-6,7,8,9-tetrahydro-5~{h}-benzo[7]annulen-5-yl]-3-propan-2-yloxy-azetidine-1-carboxamide | Human | 14069 | |
| BTK | Tec | TK | 7lty | A | C | ~{n}-[(5~{r})-2-[2-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]-6,7,8,9-tetrahydro-5~{h}-benzo[7]annulen-5-yl]-3-propan-2-yloxy-azetidine-1-carboxamide | Human | 14068 | |
| BTK | Tec | TK | 7lty | A | D | ~{n}-[(5~{r})-2-[2-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]-6,7,8,9-tetrahydro-5~{h}-benzo[7]annulen-5-yl]-3-propan-2-yloxy-azetidine-1-carboxamide | Human | 14064 | |
| BTK | Tec | TK | 7ltz | A | A | 1-~{tert}-butyl-~{n}-[(5~{r})-8-[2-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]-2-(oxetan-3-yl)-1,3,4,5-tetrahydro-2-benzazepin-5-yl]-1,2,3-triazole-4-carboxamide | Human | 14067 | |
| BTK | Tec | TK | 7ltz | A | B | 1-~{tert}-butyl-~{n}-[(5~{r})-8-[2-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]-2-(oxetan-3-yl)-1,3,4,5-tetrahydro-2-benzazepin-5-yl]-1,2,3-triazole-4-carboxamide | Human | 14066 | |
| BTK | Tec | TK | 7n4q | A | A | (2r)-2-(3-chloro-5-fluoroanilino)-2-cyclopropyl-n-[(3r)-1-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-3-yl]acetamide | Human | 14227 | |
| BTK | Tec | TK | 7n4q | A | B | (2r)-2-(3-chloro-5-fluoroanilino)-2-cyclopropyl-n-[(3r)-1-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-3-yl]acetamide | Human | 14224 | |
| BTK | Tec | TK | 7n4r | A | A | n-{2-[methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]ethyl}-n~2~-phenylglycinamide | Human | 14226 | |
| BTK | Tec | TK | 7n4r | A | B | n-{2-[methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]ethyl}-n~2~-phenylglycinamide | Human | 14228 | |
| BTK | Tec | TK | 7n4r | A | C | n-{2-[methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]ethyl}-n~2~-phenylglycinamide | Human | 14225 | |
| BTK | Tec | TK | 7n4s | A | | (3r,3'r)-3-anilino-1'-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)[1,3'-bipiperidin]-2-one | Human | 14229 | |
| BTK | Tec | TK | 7n5o | A | A | 5-(1h-benzimidazol-2-yl)-2,4-dihydro-3h-1,2,4-triazol-3-one | Human | 13896 | |
| BTK | Tec | TK | 7n5o | A | B | 5-(1h-benzimidazol-2-yl)-2,4-dihydro-3h-1,2,4-triazol-3-one | Human | 13891 | |
| BTK | Tec | TK | 7n5r | A | A | 5-phenyl-2,4-dihydro-3h-1,2,4-triazol-3-one | Human | 13895 | |
| BTK | Tec | TK | 7n5r | A | B | 5-phenyl-2,4-dihydro-3h-1,2,4-triazol-3-one | Human | 13890 | |
| BTK | Tec | TK | 7n5x | A | A | 5-(1-ethoxyisoquinolin-3-yl)-2,4-dihydro-3h-1,2,4-triazol-3-one | Human | 13893 | |
| BTK | Tec | TK | 7n5x | A | B | 5-(1-ethoxyisoquinolin-3-yl)-2,4-dihydro-3h-1,2,4-triazol-3-one | Human | 13889 | |
| BTK | Tec | TK | 7n5y | A | A | 5-(1-{[(3s)-1-propanoylpyrrolidin-3-yl]oxy}isoquinolin-3-yl)-2,4-dihydro-3h-1,2,4-triazol-3-one | Human | 13894 | |
| BTK | Tec | TK | 7n5y | A | B | 5-(1-{[(3s)-1-propanoylpyrrolidin-3-yl]oxy}isoquinolin-3-yl)-2,4-dihydro-3h-1,2,4-triazol-3-one | Human | 13892 | |
| BTK | Tec | TK | 7r60 | A | A | 2-(4-phenoxyphenoxy)-5-[(3r)-1-(prop-2-enoyl)piperidin-3-yl]pyridine-3-carboxamide | Human | 13937 | |
| BTK | Tec | TK | 7r60 | A | B | 2-(4-phenoxyphenoxy)-5-[(3r)-1-(prop-2-enoyl)piperidin-3-yl]pyridine-3-carboxamide | Human | 13939 | |
| BTK | Tec | TK | 7r61 | A | A | 5-{(3s)-1-[(z)-iminomethyl]piperidin-3-yl}-2-(4-phenoxyphenoxy)pyridine-3-carboxamide | Human | 13938 | |
| BTK | Tec | TK | 7r61 | A | B | 5-{(3s)-1-[(z)-iminomethyl]piperidin-3-yl}-2-(4-phenoxyphenoxy)pyridine-3-carboxamide | Human | 13936 | |
| BTK | Tec | TK | 7r61 | A | C | 5-{(3s)-1-[(z)-iminomethyl]piperidin-3-yl}-2-(4-phenoxyphenoxy)pyridine-3-carboxamide | Human | 13940 | |
| BTK | Tec | TK | 7yc9 | A | A | (7~{s})-2-(4-bromanyl-3,5-dimethoxy-phenyl)-7-(1-propanoylpiperidin-4-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | 14746 | |
| BTK | Tec | TK | 7yc9 | A | B | (7~{s})-2-(4-bromanyl-3,5-dimethoxy-phenyl)-7-(1-propanoylpiperidin-4-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | 14745 | |
| BTK | Tec | TK | 8e2m | A | A | (5p)-5-[4-methyl-6-(2-methylpropyl)pyridin-3-yl]-4-oxo-n-[(1r,2s)-2-propanamidocyclopentyl]-4,5-dihydro-3h-1-thia-3,5,8-triazaacenaphthylene-2-carboxamide | Human | 14552 | |
| BTK | Tec | TK | 8e2m | A | B | (5p)-5-[4-methyl-6-(2-methylpropyl)pyridin-3-yl]-4-oxo-n-[(1r,2s)-2-propanamidocyclopentyl]-4,5-dihydro-3h-1-thia-3,5,8-triazaacenaphthylene-2-carboxamide | Human | 14553 | |
| BTK | Tec | TK | 8e2m | A | C | (5p)-5-[4-methyl-6-(2-methylpropyl)pyridin-3-yl]-4-oxo-n-[(1r,2s)-2-propanamidocyclopentyl]-4,5-dihydro-3h-1-thia-3,5,8-triazaacenaphthylene-2-carboxamide | Human | 14551 | |
| BTK | Tec | TK | 8ejb | A | A | 5-[(3r)-3-(3-methyl-2-oxoimidazolidin-1-yl)piperidin-1-yl]-3-[4-(piperidin-4-yl)anilino]pyrazine-2-carboxamide | Human | 14614 | |
| BTK | Tec | TK | 8ejb | A | B | 5-[(3r)-3-(3-methyl-2-oxoimidazolidin-1-yl)piperidin-1-yl]-3-[4-(piperidin-4-yl)anilino]pyrazine-2-carboxamide | Human | 14615 | |
| BTK | Tec | TK | 8flg | A | A | n~2~-(3-chlorophenyl)-n-[(3r)-1-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-3-yl]glycinamide | Human | 14641 | |
| BTK | Tec | TK | 8flg | A | B | n~2~-(3-chlorophenyl)-n-[(3r)-1-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-3-yl]glycinamide | Human | 14634 | |
| BTK | Tec | TK | 8flh | A | A | 2-(3,5-dichloroanilino)-1-{(3r)-3-[methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]azepan-1-yl}ethan-1-one | Human | 14637 | |
| BTK | Tec | TK | 8flh | A | B | 2-(3,5-dichloroanilino)-1-{(3r)-3-[methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]azepan-1-yl}ethan-1-one | Human | 14638 | |
| BTK | Tec | TK | 8flh | A | C | 2-(3,5-dichloroanilino)-1-{(3r)-3-[methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]azepan-1-yl}ethan-1-one | Human | 14639 | |
| BTK | Tec | TK | 8fll | A | A | pirtobrutinib | Human | 14636 | |
| BTK | Tec | TK | 8fll | A | B | pirtobrutinib | Human | 14640 | |
| BTK | Tec | TK | 8fln | A | A | pirtobrutinib | Human | 14642 | |
| BTK | Tec | TK | 8fln | A | B | pirtobrutinib | Human | 14635 | |
| BTK | Tec | TK | 8fln | A | C | pirtobrutinib | Human | 14633 | |
| BTK | Tec | TK | 8flv | A | A | 2-(3,5-dichloroanilino)-1-{(3r)-3-[methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}ethan-1-one | Human | 14698 | |
| BTK | Tec | TK | 8flv | A | B | 2-(3,5-dichloroanilino)-1-{(3r)-3-[methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}ethan-1-one | Human | 14699 | |
| BTK | Tec | TK | 8flv | A | C | 2-(3,5-dichloroanilino)-1-{(3r)-3-[methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}ethan-1-one | Human | 14697 | |
| BTK | Tec | TK | 8gc7 | A | A | 5-(piperidin-1-yl)-3-[4-(piperidin-4-yl)anilino]pyrazine-2-carboxamide | Human | 15196 | |
| BTK | Tec | TK | 8gc7 | A | B | 5-(piperidin-1-yl)-3-[4-(piperidin-4-yl)anilino]pyrazine-2-carboxamide | Human | 15197 | |
| BTK | Tec | TK | 8gc8 | A | A | 5-(piperidin-1-yl)-3-[4-(piperidin-4-yl)anilino]pyrazine-2-carboxamide | Human | 15195 | |
| BTK | Tec | TK | 8gc8 | A | B | 5-(piperidin-1-yl)-3-[4-(piperidin-4-yl)anilino]pyrazine-2-carboxamide | Human | 15192 | |
| BTK | Tec | TK | 8tu3 | A | A | 1-[(4r)-4-{[(6p,8s)-6-(1-methyl-1h-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl]oxy}azepan-1-yl]propan-1-one | Human | 15362 | |
| BTK | Tec | TK | 8tu3 | A | B | 1-[(4r)-4-{[(6p,8s)-6-(1-methyl-1h-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl]oxy}azepan-1-yl]propan-1-one | Human | 15354 | |
| BTK | Tec | TK | 8tu3 | A | C | 1-[(4r)-4-{[(6p,8s)-6-(1-methyl-1h-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl]oxy}azepan-1-yl]propan-1-one | Human | 15359 | |
| BTK | Tec | TK | 8tu4 | A | A | n-methyl-n-[(1s,3r)-3-methyl-3-{[(6m,8s)-6-(1-methyl-1h-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl]oxy}cyclobutyl]propanamide | Human | 15360 | |
| BTK | Tec | TK | 8tu4 | A | B | n-methyl-n-[(1s,3r)-3-methyl-3-{[(6m,8s)-6-(1-methyl-1h-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl]oxy}cyclobutyl]propanamide | Human | 15357 | |
| BTK | Tec | TK | 8tu4 | A | C | n-methyl-n-[(1s,3r)-3-methyl-3-{[(6m,8s)-6-(1-methyl-1h-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl]oxy}cyclobutyl]propanamide | Human | 15355 | |
| BTK | Tec | TK | 8tu5 | A | A | 1-[(1s,5s,6s)-6-methyl-6-{[(6m,8r)-6-(1-methyl-1h-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl]oxy}-2-azabicyclo[3.2.0]heptan-2-yl]propan-1-one | Human | 15363 | |
| BTK | Tec | TK | 8tu5 | A | B | 1-[(1s,5s,6s)-6-methyl-6-{[(6m,8r)-6-(1-methyl-1h-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl]oxy}-2-azabicyclo[3.2.0]heptan-2-yl]propan-1-one | Human | 15358 | |
| BTK | Tec | TK | 8tu5 | A | C | 1-[(1s,5s,6s)-6-methyl-6-{[(6m,8r)-6-(1-methyl-1h-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl]oxy}-2-azabicyclo[3.2.0]heptan-2-yl]propan-1-one | Human | 15356 | |
| BTK | Tec | TK | 8u2d | A | A | (3r)-2-[n-(1h-indazole-5-carbonyl)-3-methyl-d-phenylalanyl]-n-methyl-2,3,4,9-tetrahydro-1h-pyrido[3,4-b]indole-3-carboxamide | Human | 15199 | |
| BTK | Tec | TK | 8u2d | A | B | (3r)-2-[n-(1h-indazole-5-carbonyl)-3-methyl-d-phenylalanyl]-n-methyl-2,3,4,9-tetrahydro-1h-pyrido[3,4-b]indole-3-carboxamide | Human | 15193 | |
| BTK | Tec | TK | 8u2e | A | A | (2s)-6-fluoro-5-[(3s)-3-(3-methyl-2-oxoimidazolidin-1-yl)piperidin-1-yl]-2-(4-methylpiperazine-1-carbonyl)-2,3,4,9-tetrahydro-1h-carbazole-8-carboxamide | Human | 15198 | |
| BTK | Tec | TK | 8u2e | A | B | (2s)-6-fluoro-5-[(3s)-3-(3-methyl-2-oxoimidazolidin-1-yl)piperidin-1-yl]-2-(4-methylpiperazine-1-carbonyl)-2,3,4,9-tetrahydro-1h-carbazole-8-carboxamide | Human | 15194 | |
| BTK | Tec | TK | 8yvv | A | A | - | Human | 15353 | |
| BTK | Tec | TK | 8yvv | A | B | - | Human | 15361 | |
| BUB1 | BUB | Other | 4qpm | A | | adenosine-5'-diphosphate | Human | 1843 | |
| BUB1 | BUB | Other | 4qpm | B | | adenosine-5'-diphosphate | Human | 1844 | |
| BUB1 | BUB | Other | 4r8q | A | | adenosine-5'-diphosphate | Human | 1842 | |
| BUB1 | BUB | Other | 5dmz | A | | adenosine-5'-diphosphate | Human | 6287 | |
| BUB1 | BUB | Other | 5dmz | B | | adenosine-5'-diphosphate | Human | 6286 | |
| BUB1 | BUB | Other | 6f7b | A | A | 2-[3,5-bis(fluoranyl)-4-[[3-[5-methoxy-4-[(3-methoxypyridin-4-yl)amino]pyrimidin-2-yl]indazol-1-yl]methyl]phenoxy]ethanol | Human | 10808 | |
| BUB1 | BUB | Other | 6f7b | A | B | 2-[3,5-bis(fluoranyl)-4-[[3-[5-methoxy-4-[(3-methoxypyridin-4-yl)amino]pyrimidin-2-yl]indazol-1-yl]methyl]phenoxy]ethanol | Human | 10807 | |
| BUB1B (BUBR1) | BUB | Other | 6tlj | S | | - | Human | 11992 | |
| CAMK1 (CaMK1a) | CAMK1 | CAMK | 4fg7 | A | | adenosine-5'-triphosphate | Human | 4848 | |
| CAMK1 (CaMK1a) | CAMK1 | CAMK | 4fg8 | A | | adenosine-5'-triphosphate | Human | 4850 | |
| CAMK1 (CaMK1a) | CAMK1 | CAMK | 4fg8 | B | | adenosine-5'-triphosphate | Human | 4849 | |
| CAMK1 (CaMK1a) | CAMK1 | CAMK | 4fg9 | A | | adenosine-5'-triphosphate | Human | 4846 | |
| CAMK1 (CaMK1a) | CAMK1 | CAMK | 4fg9 | B | | adenosine-5'-triphosphate | Human | 4845 | |
| CAMK1 (CaMK1a) | CAMK1 | CAMK | 4fgb | A | | - | Human | 4847 | |
| CAMK1D (CaMK1d) | CAMK1 | CAMK | 2jc6 | A | A | n-(5-methyl-1h-pyrazol-3-yl)-2-phenylquinazolin-4-amine | Human | 4829 | |
| CAMK1D (CaMK1d) | CAMK1 | CAMK | 2jc6 | A | B | n-(5-methyl-1h-pyrazol-3-yl)-2-phenylquinazolin-4-amine | Human | 4830 | |
| CAMK1D (CaMK1d) | CAMK1 | CAMK | 2jc6 | C | A | n-(5-methyl-1h-pyrazol-3-yl)-2-phenylquinazolin-4-amine | Human | 4832 | |
| CAMK1D (CaMK1d) | CAMK1 | CAMK | 2jc6 | C | B | n-(5-methyl-1h-pyrazol-3-yl)-2-phenylquinazolin-4-amine | Human | 4831 | |
| CAMK1D (CaMK1d) | CAMK1 | CAMK | 6qp5 | A | A | - | Human | 12028 | |
| CAMK1D (CaMK1d) | CAMK1 | CAMK | 6qp5 | A | B | - | Human | 12029 | |
| CAMK1D (CaMK1d) | CAMK1 | CAMK | 6t28 | A | A | 2-[(3~{s})-3-azanylpiperidin-1-yl]-4-[[2,6-di(propan-2-yl)pyridin-4-yl]amino]pyrimidine-5-carboxamide | Human | 13202 | |
| CAMK1D (CaMK1d) | CAMK1 | CAMK | 6t28 | A | B | 2-[(3~{s})-3-azanylpiperidin-1-yl]-4-[[2,6-di(propan-2-yl)pyridin-4-yl]amino]pyrimidine-5-carboxamide | Human | 13205 | |
| CAMK1D (CaMK1d) | CAMK1 | CAMK | 6t29 | A | A | 2-[(3~{s})-3-azanylpiperidin-1-yl]-4-[[3,5-bis(2-cyanopropan-2-yl)phenyl]amino]pyrimidine-5-carboxamide | Human | 13204 | |
| CAMK1D (CaMK1d) | CAMK1 | CAMK | 6t29 | A | B | 2-[(3~{s})-3-azanylpiperidin-1-yl]-4-[[3,5-bis(2-cyanopropan-2-yl)phenyl]amino]pyrimidine-5-carboxamide | Human | 13203 | |
| CAMK1D (CaMK1d) | CAMK1 | CAMK | 6t6f | A | A | 2-[(3~{s})-3-azanylpiperidin-1-yl]-4-[[3-(trifluoromethyl)phenyl]amino]pyrimidine-5-carboxamide | Human | 11939 | |
| CAMK1D (CaMK1d) | CAMK1 | CAMK | 6t6f | A | B | 2-[(3~{s})-3-azanylpiperidin-1-yl]-4-[[3-(trifluoromethyl)phenyl]amino]pyrimidine-5-carboxamide | Human | 11940 | |
| CAMK1D (CaMK1d) | CAMK1 | CAMK | 6t6f | B | A | 2-[(3~{s})-3-azanylpiperidin-1-yl]-4-[[3-(trifluoromethyl)phenyl]amino]pyrimidine-5-carboxamide | Human | 11941 | |
| CAMK1D (CaMK1d) | CAMK1 | CAMK | 6t6f | B | B | 2-[(3~{s})-3-azanylpiperidin-1-yl]-4-[[3-(trifluoromethyl)phenyl]amino]pyrimidine-5-carboxamide | Human | 11942 | |
| CAMK1D (CaMK1d) | CAMK1 | CAMK | 8bfm | A | | pyrazolo[5,1-a]phthalazin-6-amine | Human | 14516 | |
| CAMK1D (CaMK1d) | CAMK1 | CAMK | 8bfs | A | A | 3~{h}-pyrrolo[2,3-c]isoquinolin-5-amine | Human | 14506 | |
| CAMK1D (CaMK1d) | CAMK1 | CAMK | 8bfs | A | B | 3~{h}-pyrrolo[2,3-c]isoquinolin-5-amine | Human | 14505 | |
| CAMK1G (CaMK1g) | CAMK1 | CAMK | 2jam | A | A | 5-[(e)-(5-chloro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-n-[2-(diethylamino)ethyl]-2,4-dimethyl-1h-pyrrole-3-carboxamide | Human | 1218 | |
| CAMK1G (CaMK1g) | CAMK1 | CAMK | 2jam | A | B | 5-[(e)-(5-chloro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-n-[2-(diethylamino)ethyl]-2,4-dimethyl-1h-pyrrole-3-carboxamide | Human | 1221 | |
| CAMK1G (CaMK1g) | CAMK1 | CAMK | 2jam | B | A | 5-[(e)-(5-chloro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-n-[2-(diethylamino)ethyl]-2,4-dimethyl-1h-pyrrole-3-carboxamide | Human | 1220 | |
| CAMK1G (CaMK1g) | CAMK1 | CAMK | 2jam | B | B | 5-[(e)-(5-chloro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-n-[2-(diethylamino)ethyl]-2,4-dimethyl-1h-pyrrole-3-carboxamide | Human | 1219 | |
| Camk2a (CaMK2a) | CAMK2 | CAMK | 7b55 | A | A | - | Mouse | 14244 | |
| Camk2a (CaMK2a) | CAMK2 | CAMK | 7b55 | A | B | - | Mouse | 14247 | |
| Camk2a (CaMK2a) | CAMK2 | CAMK | 7b56 | A | A | - | Mouse | 14245 | |
| Camk2a (CaMK2a) | CAMK2 | CAMK | 7b56 | A | B | - | Mouse | 14249 | |
| Camk2a (CaMK2a) | CAMK2 | CAMK | 7b57 | A | A | - | Mouse | 14246 | |
| Camk2a (CaMK2a) | CAMK2 | CAMK | 7b57 | A | B | - | Mouse | 14248 | |
| CAMK2A (CaMK2a) | CAMK2 | CAMK | 2vz6 | A | A | (2z,3e)-2,3'-biindole-2',3(1h,1'h)-dione 3-{o-[(3r)-3,4-dihydroxybutyl]oxime} | Human | 2472 | |
| CAMK2A (CaMK2a) | CAMK2 | CAMK | 2vz6 | A | B | (2z,3e)-2,3'-biindole-2',3(1h,1'h)-dione 3-{o-[(3r)-3,4-dihydroxybutyl]oxime} | Human | 2471 | |
| CAMK2A (CaMK2a) | CAMK2 | CAMK | 2vz6 | B | A | (2z,3e)-2,3'-biindole-2',3(1h,1'h)-dione 3-{o-[(3r)-3,4-dihydroxybutyl]oxime} | Human | 2474 | |
| CAMK2A (CaMK2a) | CAMK2 | CAMK | 2vz6 | B | B | (2z,3e)-2,3'-biindole-2',3(1h,1'h)-dione 3-{o-[(3r)-3,4-dihydroxybutyl]oxime} | Human | 2470 | |
| CAMK2A (CaMK2a) | CAMK2 | CAMK | 3soa | A | | 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile | Human | 2473 | |
| CAMK2A (CaMK2a) | CAMK2 | CAMK | 6vzk | A | | 4'-hydroxycinnamic acid | Human | 12165 | |
| CAMK2A (CaMK2a) | CAMK2 | CAMK | 6w4o | O | | - | Human | 12485 | |
| CAMK2A (CaMK2a) | CAMK2 | CAMK | 6w4p | H | | - | Human | 12484 | |
| CAMK2A (CaMK2a) | CAMK2 | CAMK | 6x5g | A | A | - | Human | 13061 | |
| CAMK2A (CaMK2a) | CAMK2 | CAMK | 6x5g | A | B | - | Human | 13068 | |
| CAMK2A (CaMK2a) | CAMK2 | CAMK | 6x5q | A | | - | Human | 13056 | |
| CAMK2A (CaMK2a) | CAMK2 | CAMK | 7kl0 | A | | methyl 6-o-(heptylcarbamoyl)-beta-l-altropyranoside | Human | 13111 | |
| CAMK2A (CaMK2a) | CAMK2 | CAMK | 7kl0 | B | | methyl 6-o-(heptylcarbamoyl)-beta-l-altropyranoside | Human | 13114 | |
| CAMK2A (CaMK2a) | CAMK2 | CAMK | 7kl1 | A | | adenosine-5'-triphosphate | Human | 13059 | |
| CAMK2A (CaMK2a) | CAMK2 | CAMK | 7kl1 | B | | adenosine-5'-triphosphate | Human | 13062 | |
| CAMK2A (CaMK2a) | CAMK2 | CAMK | 7kl2 | A | | - | Human | 13064 | |
| CAMK2A (CaMK2a) | CAMK2 | CAMK | 7uiq | A | | - | Human | 14175 | |
| CAMK2A (CaMK2a) | CAMK2 | CAMK | 7uir | A | | adenosine-5'-triphosphate | Human | 14173 | |
| CAMK2A (CaMK2a) | CAMK2 | CAMK | 7uis | A | | - | Human | 14174 | |
| CAMK2A (CaMK2a) | CAMK2 | CAMK | 7ujp | A | | adenosine-5'-diphosphate | Human | 14193 | |
| CAMK2A (CaMK2a) | CAMK2 | CAMK | 7ujq | A | | methyl 6-o-(heptylcarbamoyl)-beta-l-altropyranoside | Human | 14189 | |
| CAMK2A (CaMK2a) | CAMK2 | CAMK | 7ujr | A | | - | Human | 14191 | |
| CAMK2A (CaMK2a) | CAMK2 | CAMK | 7ujs | A | | adenosine-5'-diphosphate | Human | 14190 | |
| CAMK2A (CaMK2a) | CAMK2 | CAMK | 7ujt | A | | adenosine-5'-triphosphate | Human | 14192 | |
| CAMK2B (CaMK2b) | CAMK2 | CAMK | 3bhh | A | | [4-({4-[(5-cyclopropyl-1h-pyrazol-3-yl)amino]-6-(methylamino)pyrimidin-2-yl}amino)phenyl]acetonitrile | Human | 1507 | |
| CAMK2B (CaMK2b) | CAMK2 | CAMK | 3bhh | B | | [4-({4-[(5-cyclopropyl-1h-pyrazol-3-yl)amino]-6-(methylamino)pyrimidin-2-yl}amino)phenyl]acetonitrile | Human | 1506 | |
| CAMK2B (CaMK2b) | CAMK2 | CAMK | 3bhh | C | | - | Human | 1505 | |
| CAMK2B (CaMK2b) | CAMK2 | CAMK | 3bhh | D | | - | Human | 1504 | |
| Camk2d (CaMK2d) | CAMK2 | CAMK | 6bab | A | A | n-[(2s)-2-(diethylamino)propyl]-2-(3-hydroxyazetidin-1-yl)-6-[5-(thiophen-2-yl)pyrazolo[1,5-a]pyrimidin-3-yl]pyridine-4-carboxamide | Mouse | 8694 | |
| Camk2d (CaMK2d) | CAMK2 | CAMK | 6bab | A | B | n-[(2s)-2-(diethylamino)propyl]-2-(3-hydroxyazetidin-1-yl)-6-[5-(thiophen-2-yl)pyrazolo[1,5-a]pyrimidin-3-yl]pyridine-4-carboxamide | Mouse | 8691 | |
| Camk2d (CaMK2d) | CAMK2 | CAMK | 6bab | B | A | n-[(2s)-2-(diethylamino)propyl]-2-(3-hydroxyazetidin-1-yl)-6-[5-(thiophen-2-yl)pyrazolo[1,5-a]pyrimidin-3-yl]pyridine-4-carboxamide | Mouse | 8690 | |
| Camk2d (CaMK2d) | CAMK2 | CAMK | 6bab | B | B | n-[(2s)-2-(diethylamino)propyl]-2-(3-hydroxyazetidin-1-yl)-6-[5-(thiophen-2-yl)pyrazolo[1,5-a]pyrimidin-3-yl]pyridine-4-carboxamide | Mouse | 8693 | |
| Camk2d (CaMK2d) | CAMK2 | CAMK | 6bab | C | A | n-[(2s)-2-(diethylamino)propyl]-2-(3-hydroxyazetidin-1-yl)-6-[5-(thiophen-2-yl)pyrazolo[1,5-a]pyrimidin-3-yl]pyridine-4-carboxamide | Mouse | 8697 | |
| Camk2d (CaMK2d) | CAMK2 | CAMK | 6bab | C | B | n-[(2s)-2-(diethylamino)propyl]-2-(3-hydroxyazetidin-1-yl)-6-[5-(thiophen-2-yl)pyrazolo[1,5-a]pyrimidin-3-yl]pyridine-4-carboxamide | Mouse | 8692 | |
| Camk2d (CaMK2d) | CAMK2 | CAMK | 6bab | D | A | n-[(2s)-2-(diethylamino)propyl]-2-(3-hydroxyazetidin-1-yl)-6-[5-(thiophen-2-yl)pyrazolo[1,5-a]pyrimidin-3-yl]pyridine-4-carboxamide | Mouse | 8695 | |
| Camk2d (CaMK2d) | CAMK2 | CAMK | 6bab | D | B | n-[(2s)-2-(diethylamino)propyl]-2-(3-hydroxyazetidin-1-yl)-6-[5-(thiophen-2-yl)pyrazolo[1,5-a]pyrimidin-3-yl]pyridine-4-carboxamide | Mouse | 8696 | |
| CAMK2D (CaMK2d) | CAMK2 | CAMK | 2vn9 | A | | [4-({4-[(5-cyclopropyl-1h-pyrazol-3-yl)amino]quinazolin-2-yl}imino)cyclohexa-2,5-dien-1-yl]acetonitrile | Human | 2140 | |
| CAMK2D (CaMK2d) | CAMK2 | CAMK | 2vn9 | B | | [4-({4-[(5-cyclopropyl-1h-pyrazol-3-yl)amino]quinazolin-2-yl}imino)cyclohexa-2,5-dien-1-yl]acetonitrile | Human | 2139 | |
| CAMK2D (CaMK2d) | CAMK2 | CAMK | 2wel | A | A | (3z)-n,n-dimethyl-2-oxo-3-(4,5,6,7-tetrahydro-1h-indol-2-ylmethylidene)-2,3-dihydro-1h-indole-5-sulfonamide | Human | 2138 | |
| CAMK2D (CaMK2d) | CAMK2 | CAMK | 2wel | A | B | (3z)-n,n-dimethyl-2-oxo-3-(4,5,6,7-tetrahydro-1h-indol-2-ylmethylidene)-2,3-dihydro-1h-indole-5-sulfonamide | Human | 2137 | |
| CAMK2D (CaMK2d) | CAMK2 | CAMK | 2wel | A | C | (3z)-n,n-dimethyl-2-oxo-3-(4,5,6,7-tetrahydro-1h-indol-2-ylmethylidene)-2,3-dihydro-1h-indole-5-sulfonamide | Human | 2136 | |
| CAMK2D (CaMK2d) | CAMK2 | CAMK | 5vlo | A | | n-[(2s)-2-(diethylamino)propyl]-2-[(2s)-2-(methylcarbamoyl)azetidin-1-yl]-6-[5-(thiophen-2-yl)pyrazolo[1,5-a]pyrimidin-3-yl]pyridine-4-carboxamide | Human | 8348 | |
| CAMK2D (CaMK2d) | CAMK2 | CAMK | 5vlo | B | | n-[(2s)-2-(diethylamino)propyl]-2-[(2s)-2-(methylcarbamoyl)azetidin-1-yl]-6-[5-(thiophen-2-yl)pyrazolo[1,5-a]pyrimidin-3-yl]pyridine-4-carboxamide | Human | 8347 | |
| CAMK2D (CaMK2d) | CAMK2 | CAMK | 6ayw | A | | n-[2-(dimethylamino)ethyl]-3-[6-(thiophen-2-yl)imidazo[1,2-b]pyridazin-3-yl]benzamide | Human | 8666 | |
| CAMK2D (CaMK2d) | CAMK2 | CAMK | 6ayw | B | | n-[2-(dimethylamino)ethyl]-3-[6-(thiophen-2-yl)imidazo[1,2-b]pyridazin-3-yl]benzamide | Human | 8665 | |
| CAMK2D (CaMK2d) | CAMK2 | CAMK | 8uso | A | | - | Human | 15247 | |
| CAMK2G (CaMK2g) | CAMK2 | CAMK | 2v7o | A | A | - | Human | 7239 | |
| CAMK2G (CaMK2g) | CAMK2 | CAMK | 2v7o | A | B | - | Human | 7238 | |
| CAMK4 (CaMK4) | CAMK1 | CAMK | 2w4o | A | | 5-amino-3-{[4-(aminosulfonyl)phenyl]amino}-n-(2,6-difluorophenyl)-1h-1,2,4-triazole-1-carbothioamide | Human | 2687 | |
| CAMKK1 (CaMKK1) | CAMKK | Other | 6ccf | A | | n-[2-oxo-3-((e)-phenyl{[4-(piperidin-1-ylmethyl)phenyl]imino}methyl)-2,6-dihydro-1h-indol-5-yl]ethanesulfonamide | Human | 9712 | |
| CAMKK1 (CaMKK1) | CAMKK | Other | 6ccf | B | | n-[2-oxo-3-((e)-phenyl{[4-(piperidin-1-ylmethyl)phenyl]imino}methyl)-2,6-dihydro-1h-indol-5-yl]ethanesulfonamide | Human | 9717 | |
| CAMKK1 (CaMKK1) | CAMKK | Other | 6cd6 | A | A | 2-cyclopentyl-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid | Human | 9716 | |
| CAMKK1 (CaMKK1) | CAMKK | Other | 6cd6 | A | B | 2-cyclopentyl-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid | Human | 9714 | |
| CAMKK1 (CaMKK1) | CAMKK | Other | 6cd6 | B | A | 2-cyclopentyl-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid | Human | 9709 | |
| CAMKK1 (CaMKK1) | CAMKK | Other | 6cd6 | B | B | 2-cyclopentyl-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid | Human | 9713 | |
| CAMKK1 (CaMKK1) | CAMKK | Other | 6cd6 | C | A | 2-cyclopentyl-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid | Human | 9711 | |
| CAMKK1 (CaMKK1) | CAMKK | Other | 6cd6 | C | B | 2-cyclopentyl-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid | Human | 9715 | |
| CAMKK1 (CaMKK1) | CAMKK | Other | 6cd6 | D | A | 2-cyclopentyl-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid | Human | 9710 | |
| CAMKK1 (CaMKK1) | CAMKK | Other | 6cd6 | D | B | 2-cyclopentyl-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid | Human | 9708 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 2zv2 | A | | 7-oxo-7h-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid | Human | 406 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 5uy6 | A | | 2-cyclopentyl-4-(5-phenylfuro[2,3-b]pyridin-3-yl)benzoic acid | Human | 7982 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 5uyj | A | A | 2-cyclopentyl-4-(7-methoxyquinolin-4-yl)benzoic acid | Human | 7560 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 5uyj | A | B | 2-cyclopentyl-4-(7-methoxyquinolin-4-yl)benzoic acid | Human | 7559 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 5vt1 | A | | 4-({5-[(3-hydroxy-4-methylphenyl)amino]-4-oxo-4h-1,2,6-thiadiazin-3-yl}amino)benzamide | Human | 7591 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 5yv8 | A | A | 1-amino-4-hydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid | Human | 10753 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 5yv8 | A | B | 1-amino-4-hydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid | Human | 10755 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 5yv9 | A | | 5-chloro-2-methoxy-4[(1z)-3-(4-methoxyphenyl)-3-oxoprop-1-en-1-yl]aminobenzoic acid | Human | 10752 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 5yva | A | | 3-(1h-tetrazol-5-yl)-10lambda~6~-thioxanthene-9,10,10-trione | Human | 10750 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 5yvb | A | | (3z)-5-chloro-3-[(1-methyl-1h-pyrazol-4-yl)methylidene]-1,3-dihydro-2h-indol-2-one | Human | 10751 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 5yvc | A | | 3-{2,4-dimethyl-5-[(z)-(2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-1h-pyrrol-3-yl}propanoic acid | Human | 10754 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 6bku | A | | 2-cyclopentyl-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid | Human | 8687 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 6ble | A | A | 1-{2-[5-(2-methoxyethoxy)-1h-benzimidazol-1-yl]quinolin-8-yl}piperidin-4-amine | Human | 8688 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 6ble | A | B | 1-{2-[5-(2-methoxyethoxy)-1h-benzimidazol-1-yl]quinolin-8-yl}piperidin-4-amine | Human | 8689 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 6bql | A | | 2-({5-chloro-2-[(2-methoxy-4-morpholin-4-ylphenyl)amino]pyrimidin-4-yl}amino)-n-methylbenzamide | Human | 9061 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 6bqp | A | | 1-(2-{5-[(3-methyloxetan-3-yl)methoxy]-1h-benzimidazol-1-yl}quinolin-8-yl)piperidin-4-amine | Human | 9064 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 6bqq | A | | 4-{[(7r)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxy-n-(1-methylpiperidin-4-yl)benzamide | Human | 9063 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 6brc | A | | 5-chloro-n~2~-{4-[4-(dimethylamino)piperidin-1-yl]-2-methoxyphenyl}-n~4~-[2-(dimethylphosphoryl)phenyl]pyrimidine-2,4-diamine | Human | 9062 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 6brc | B | | 5-chloro-n~2~-{4-[4-(dimethylamino)piperidin-1-yl]-2-methoxyphenyl}-n~4~-[2-(dimethylphosphoryl)phenyl]pyrimidine-2,4-diamine | Human | 9060 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 6cmj | A | A | 2-(2-methylpropyl)-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid | Human | 9784 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 6cmj | A | B | 2-(2-methylpropyl)-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid | Human | 9783 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 6cmj | B | A | 2-(2-methylpropyl)-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid | Human | 9786 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 6cmj | B | B | 2-(2-methylpropyl)-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid | Human | 9785 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 8tuc | A | A | (4m)-2-cyclopentyl-4-(7-ethoxyquinazolin-4-yl)benzoic acid | Human | 15005 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 8tuc | A | B | (4m)-2-cyclopentyl-4-(7-ethoxyquinazolin-4-yl)benzoic acid | Human | 15004 | |
| CASK | CASK | CAMK | 3c0g | A | A | [(2r,3s,4r,5r)-5-(6-aminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] dihydrogen phosphate | Human | 3828 | |
| CASK | CASK | CAMK | 3c0g | A | B | [(2r,3s,4r,5r)-5-(6-aminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] dihydrogen phosphate | Human | 3827 | |
| CASK | CASK | CAMK | 3c0g | B | A | [(2r,3s,4r,5r)-5-(6-aminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] dihydrogen phosphate | Human | 3824 | |
| CASK | CASK | CAMK | 3c0g | B | B | [(2r,3s,4r,5r)-5-(6-aminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] dihydrogen phosphate | Human | 3826 | |
| CASK | CASK | CAMK | 3c0h | A | | adenosine monophosphate | Human | 3825 | |
| CASK | CASK | CAMK | 3c0h | B | | adenosine monophosphate | Human | 3817 | |
| CASK | CASK | CAMK | 3c0i | A | A | [(2r,3s,4r,5r)-5-(6-aminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] dihydrogen phosphate | Human | 3830 | |
| CASK | CASK | CAMK | 3c0i | A | B | [(2r,3s,4r,5r)-5-(6-aminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] dihydrogen phosphate | Human | 3819 | |
| CASK | CASK | CAMK | 3mfr | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 3822 | |
| CASK | CASK | CAMK | 3mfr | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 3831 | |
| CASK | CASK | CAMK | 3mfs | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 3818 | |
| CASK | CASK | CAMK | 3mfs | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 3829 | |
| CASK | CASK | CAMK | 3mft | A | A | - | Human | 3823 | |
| CASK | CASK | CAMK | 3mft | A | B | - | Human | 3821 | |
| CASK | CASK | CAMK | 3mfu | A | A | phosphoaminophosphonic acid-adenylate ester | Human | 3816 | |
| CASK | CASK | CAMK | 3mfu | A | B | phosphoaminophosphonic acid-adenylate ester | Human | 3832 | |
| CASK | CASK | CAMK | 3tac | A | | - | Human | 3820 | |
| CASK | CASK | CAMK | 6kmh | A | | - | Human | 12672 | |
| CASK | CASK | CAMK | 6kmh | B | | - | Human | 12671 | |
| CASK | CASK | CAMK | 7oai | A | A | 4-(cyclopentylamino)-2-[(2,5-dichlorophenyl)methylamino]-n-[3-(2-oxo-1,3-oxazolidin-3-yl)propyl]pyrimidine-5-carboxamide | Human | 13584 | |
| CASK | CASK | CAMK | 7oai | A | B | 4-(cyclopentylamino)-2-[(2,5-dichlorophenyl)methylamino]-n-[3-(2-oxo-1,3-oxazolidin-3-yl)propyl]pyrimidine-5-carboxamide | Human | 13583 | |
| CASK | CASK | CAMK | 7oaj | A | A | 4-(cyclopentylamino)-2-[(3,4-dichlorophenyl)methylamino]-n-[3-(2-oxidanylidenepyrrolidin-1-yl)propyl]pyrimidine-5-carboxamide | Human | 13582 | |
| CASK | CASK | CAMK | 7oaj | A | B | 4-(cyclopentylamino)-2-[(3,4-dichlorophenyl)methylamino]-n-[3-(2-oxidanylidenepyrrolidin-1-yl)propyl]pyrimidine-5-carboxamide | Human | 13581 | |
| CASK | CASK | CAMK | 7oak | A | | 2-[[2,5-bis(bromanyl)-4-methyl-phenyl]methylamino]-4-(cyclopentylamino)-n-[3-(2-oxidanylidene-1,3-oxazolidin-3-yl)propyl]pyrimidine-5-carboxamide | Human | 13585 | |
| CASK | CASK | CAMK | 7oal | A | | 2-[[2,5-bis(bromanyl)-4-methyl-phenyl]methylamino]-4-(cyclohexylamino)-n-[3-(2-oxidanylidene-1,3-oxazolidin-3-yl)propyl]pyrimidine-5-carboxamide | Human | 13586 | |
| CDC42BPB (MRCKb) | DMPK | AGC | 3qfv | A | | 2-(carbamoylamino)-5-(4-fluorophenyl)thiophene-3-carboxamide | Human | 4860 | |
| CDC42BPB (MRCKb) | DMPK | AGC | 3qfv | B | | 2-(carbamoylamino)-5-(4-fluorophenyl)thiophene-3-carboxamide | Human | 4857 | |
| CDC42BPB (MRCKb) | DMPK | AGC | 3tku | A | | 5-(1,4-diazepan-1-sulfonyl)isoquinoline | Human | 4862 | |
| CDC42BPB (MRCKb) | DMPK | AGC | 3tku | B | | 5-(1,4-diazepan-1-sulfonyl)isoquinoline | Human | 4859 | |
| CDC42BPB (MRCKb) | DMPK | AGC | 4uak | A | A | adenosine-5'-diphosphate | Human | 4864 | |
| CDC42BPB (MRCKb) | DMPK | AGC | 4uak | A | B | adenosine-5'-diphosphate | Human | 4863 | |
| CDC42BPB (MRCKb) | DMPK | AGC | 4ual | A | A | 4-chloro-1-(piperidin-4-yl)-n-[3-(pyridin-2-yl)-1h-pyrazol-4-yl]-1h-pyrazole-3-carboxamide | Human | 4861 | |
| CDC42BPB (MRCKb) | DMPK | AGC | 4ual | A | B | 4-chloro-1-(piperidin-4-yl)-n-[3-(pyridin-2-yl)-1h-pyrazol-4-yl]-1h-pyrazole-3-carboxamide | Human | 4858 | |
| CDC42BPB (MRCKb) | DMPK | AGC | 5ote | A | | 2-[4-[(6~{s})-1,8-diazaspiro[5.5]undecan-8-yl]-1~{h}-pyrrolo[2,3-b]pyridin-3-yl]-1,3-thiazole | Human | 9578 | |
| CDC42BPB (MRCKb) | DMPK | AGC | 5otf | A | | (6~{s})-8-(3-pyrimidin-4-yl-1~{h}-pyrrolo[2,3-b]pyridin-4-yl)-1,8-diazaspiro[5.5]undecane | Human | 9577 | |
| CDC7 | CDC7 | Other | 4f99 | A | | adenosine-5'-diphosphate | Human | 4824 | |
| CDC7 | CDC7 | Other | 4f9a | A | | adenosine-5'-diphosphate | Human | 4825 | |
| CDC7 | CDC7 | Other | 4f9a | C | | adenosine-5'-diphosphate | Human | 4826 | |
| CDC7 | CDC7 | Other | 4f9b | A | | 2-(pyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one | Human | 4828 | |
| CDC7 | CDC7 | Other | 4f9b | C | | 2-(pyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one | Human | 4827 | |
| CDC7 | CDC7 | Other | 4f9c | A | | 8-chloro-2-[(2s)-pyrrolidin-2-yl][1]benzofuro[3,2-d]pyrimidin-4(3h)-one | Human | 4823 | |
| CDC7 | CDC7 | Other | 6ya6 | A | A | 8-chloro-2-[(2s)-pyrrolidin-2-yl][1]benzofuro[3,2-d]pyrimidin-4(3h)-one | Human | 13844 | |
| CDC7 | CDC7 | Other | 6ya6 | A | B | 8-chloro-2-[(2s)-pyrrolidin-2-yl][1]benzofuro[3,2-d]pyrimidin-4(3h)-one | Human | 13841 | |
| CDC7 | CDC7 | Other | 6ya7 | A | A | adenosine-5'-diphosphate | Human | 13845 | |
| CDC7 | CDC7 | Other | 6ya7 | A | B | adenosine-5'-diphosphate | Human | 13842 | |
| CDC7 | CDC7 | Other | 6ya8 | A | A | adenosine-5'-diphosphate | Human | 13846 | |
| CDC7 | CDC7 | Other | 6ya8 | A | B | adenosine-5'-diphosphate | Human | 13843 | |
| CDK1 (CDC2) | CDK | CMGC | 4y72 | A | A | {[(2,6-difluorophenyl)carbonyl]amino}-n-(4-fluorophenyl)-1h-pyrazole-3-carboxamide | Human | 4610 | |
| CDK1 (CDC2) | CDK | CMGC | 4y72 | A | B | {[(2,6-difluorophenyl)carbonyl]amino}-n-(4-fluorophenyl)-1h-pyrazole-3-carboxamide | Human | 4609 | |
| CDK1 (CDC2) | CDK | CMGC | 4yc3 | A | A | - | Human | 6555 | |
| CDK1 (CDC2) | CDK | CMGC | 4yc3 | A | B | - | Human | 6554 | |
| CDK1 (CDC2) | CDK | CMGC | 4yc6 | A | A | - | Human | 4607 | |
| CDK1 (CDC2) | CDK | CMGC | 4yc6 | A | B | - | Human | 4616 | |
| CDK1 (CDC2) | CDK | CMGC | 4yc6 | C | A | - | Human | 4608 | |
| CDK1 (CDC2) | CDK | CMGC | 4yc6 | C | B | - | Human | 4611 | |
| CDK1 (CDC2) | CDK | CMGC | 4yc6 | E | A | - | Human | 4612 | |
| CDK1 (CDC2) | CDK | CMGC | 4yc6 | E | B | - | Human | 4614 | |
| CDK1 (CDC2) | CDK | CMGC | 4yc6 | G | A | - | Human | 4613 | |
| CDK1 (CDC2) | CDK | CMGC | 4yc6 | G | B | - | Human | 4615 | |
| CDK1 (CDC2) | CDK | CMGC | 5hq0 | A | A | {[(2,6-difluorophenyl)carbonyl]amino}-n-(4-fluorophenyl)-1h-pyrazole-3-carboxamide | Human | 6422 | |
| CDK1 (CDC2) | CDK | CMGC | 5hq0 | A | B | {[(2,6-difluorophenyl)carbonyl]amino}-n-(4-fluorophenyl)-1h-pyrazole-3-carboxamide | Human | 6421 | |
| CDK1 (CDC2) | CDK | CMGC | 5lqf | A | A | o6-cyclohexylmethoxy-2-(4'-sulphamoylanilino) purine | Human | 7364 | |
| CDK1 (CDC2) | CDK | CMGC | 5lqf | A | B | o6-cyclohexylmethoxy-2-(4'-sulphamoylanilino) purine | Human | 7366 | |
| CDK1 (CDC2) | CDK | CMGC | 5lqf | D | A | o6-cyclohexylmethoxy-2-(4'-sulphamoylanilino) purine | Human | 7365 | |
| CDK1 (CDC2) | CDK | CMGC | 5lqf | D | B | o6-cyclohexylmethoxy-2-(4'-sulphamoylanilino) purine | Human | 7367 | |
| CDK1 (CDC2) | CDK | CMGC | 6gu2 | A | A | 2-(2-chlorophenyl)-8-[(3~{r},4~{r})-1-methyl-3-oxidanyl-piperidin-4-yl]-5,7-bis(oxidanyl)chromen-4-one | Human | 10780 | |
| CDK1 (CDC2) | CDK | CMGC | 6gu2 | A | B | 2-(2-chlorophenyl)-8-[(3~{r},4~{r})-1-methyl-3-oxidanyl-piperidin-4-yl]-5,7-bis(oxidanyl)chromen-4-one | Human | 10776 | |
| CDK1 (CDC2) | CDK | CMGC | 6gu3 | A | | 4-(2-methyl-3-propan-2-yl-imidazol-4-yl)-~{n}-(4-methylsulfonylphenyl)pyrimidin-2-amine | Human | 10778 | |
| CDK1 (CDC2) | CDK | CMGC | 6gu4 | A | | ~{n}2-[(1~{r},2~{s})-2-azanylcyclohexyl]-~{n}6-(3-chlorophenyl)-9-ethyl-purine-2,6-diamine | Human | 10777 | |
| CDK1 (CDC2) | CDK | CMGC | 6gu6 | A | | 3-[({3-ethyl-5-[(2s)-2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl}amino)methyl]-1-hydroxypyridinium | Human | 10774 | |
| CDK1 (CDC2) | CDK | CMGC | 6gu7 | A | | 4-(2-methyl-3-propan-2-yl-imidazol-4-yl)-~{n}-(4-methylsulfonylphenyl)pyrimidin-2-amine | Human | 10781 | |
| CDK1 (CDC2) | CDK | CMGC | 6gu7 | C | | - | Human | 10775 | |
| CDK1 (CDC2) | CDK | CMGC | 6gu7 | E | | - | Human | 10782 | |
| CDK1 (CDC2) | CDK | CMGC | 6gu7 | G | | - | Human | 10779 | |
| CDK1 (CDC2) | CDK | CMGC | 7nj0 | B | | - | Human | 13827 | |
| CDK12 (CRK7) | CDK | CMGC | 4cxa | A | | phosphoaminophosphonic acid-adenylate ester | Human | 4856 | |
| CDK12 (CRK7) | CDK | CMGC | 4cxa | C | | - | Human | 4853 | |
| CDK12 (CRK7) | CDK | CMGC | 4nst | A | | adenosine-5'-diphosphate | Human | 4852 | |
| CDK12 (CRK7) | CDK | CMGC | 4nst | C | | adenosine-5'-diphosphate | Human | 4851 | |
| CDK12 (CRK7) | CDK | CMGC | 4un0 | C | | - | Human | 4854 | |
| CDK12 (CRK7) | CDK | CMGC | 4un0 | D | | - | Human | 4855 | |
| CDK12 (CRK7) | CDK | CMGC | 5acb | C | | n-[4-[(3r)-3-[[5-chloranyl-4-(1h-indol-3-yl)pyrimidin-2-yl]amino]piperidin-1-yl]carbonylphenyl]-4-(dimethylamino)butanamide | Human | 6701 | |
| CDK12 (CRK7) | CDK | CMGC | 5acb | D | | n-[4-[(3r)-3-[[5-chloranyl-4-(1h-indol-3-yl)pyrimidin-2-yl]amino]piperidin-1-yl]carbonylphenyl]-4-(dimethylamino)butanamide | Human | 6702 | |
| CDK12 (CRK7) | CDK | CMGC | 6b3e | A | | 2-[(2s)-1-(6-{[(4,5-difluoro-1h-benzimidazol-2-yl)methyl]amino}-9-ethyl-9h-purin-2-yl)piperidin-2-yl]ethan-1-ol | Human | 9452 | |
| CDK12 (CRK7) | CDK | CMGC | 6b3e | C | | 2-[(2s)-1-(6-{[(4,5-difluoro-1h-benzimidazol-2-yl)methyl]amino}-9-ethyl-9h-purin-2-yl)piperidin-2-yl]ethan-1-ol | Human | 9453 | |
| CDK12 (CRK7) | CDK | CMGC | 6ckx | A | | n-[4-(1-methyl-1h-pyrazol-4-yl)phenyl]-n-{trans-4-[(quinazolin-2-yl)amino]cyclohexyl}acetamide | Human | 10578 | |
| CDK12 (CRK7) | CDK | CMGC | 6ckx | C | | n-[4-(1-methyl-1h-pyrazol-4-yl)phenyl]-n-{trans-4-[(quinazolin-2-yl)amino]cyclohexyl}acetamide | Human | 10579 | |
| CDK12 (CRK7) | CDK | CMGC | 6td3 | B | | (2r)-2-({9-(1-methylethyl)-6-[(4-pyridin-2-ylbenzyl)amino]-9h-purin-2-yl}amino)butan-1-ol | Human | 12371 | |
| CDK12 (CRK7) | CDK | CMGC | 6td3 | E | | (2r)-2-({9-(1-methylethyl)-6-[(4-pyridin-2-ylbenzyl)amino]-9h-purin-2-yl}amino)butan-1-ol | Human | 12369 | |
| CDK12 (CRK7) | CDK | CMGC | 6td3 | H | | (2r)-2-({9-(1-methylethyl)-6-[(4-pyridin-2-ylbenzyl)amino]-9h-purin-2-yl}amino)butan-1-ol | Human | 12370 | |
| CDK12 (CRK7) | CDK | CMGC | 7nxk | A | | (e)-n-[4-[(1r,3r)-3-[[5-chloranyl-4-(1h-indol-3-yl)pyrimidin-2-yl]amino]cyclohexyl]oxyphenyl]-4-(dimethylamino)but-2-enamide | Human | 13547 | |
| CDK12 (CRK7) | CDK | CMGC | 8bu1 | B | | (2~{r})-2-[[6-[[5,6-bis(chloranyl)-1~{h}-benzimidazol-2-yl]methylamino]-9-(1-methylpyrazol-4-yl)purin-2-yl]amino]butan-1-ol | Human | 14930 | |
| CDK12 (CRK7) | CDK | CMGC | 8bu2 | B | | ~{n}-[[5,6-bis(chloranyl)-1~{h}-benzimidazol-2-yl]methyl]-2-morpholin-4-yl-9-propan-2-yl-purin-6-amine | Human | 14918 | |
| CDK12 (CRK7) | CDK | CMGC | 8bu3 | B | | 2-morpholin-4-yl-9-propan-2-yl-~{n}-[(4-pyridin-2-ylphenyl)methyl]purin-6-amine | Human | 14931 | |
| CDK12 (CRK7) | CDK | CMGC | 8bu4 | B | | (2~{r})-2-[[6-[[5,6-bis(chloranyl)-1~{h}-benzimidazol-2-yl]methylamino]-9-(1-methylpyrazol-4-yl)purin-2-yl]amino]butan-1-ol | Human | 14910 | |
| CDK12 (CRK7) | CDK | CMGC | 8bu5 | B | | ~{n}-[[5,6-bis(chloranyl)-1~{h}-benzimidazol-2-yl]methyl]-9-(1-methylpyrazol-4-yl)-2-morpholin-4-yl-purin-6-amine | Human | 14926 | |
| CDK12 (CRK7) | CDK | CMGC | 8bu6 | B | | ~{n}-(1~{h}-benzimidazol-2-ylmethyl)-9-(1-methylpyrazol-4-yl)-2-morpholin-4-yl-purin-6-amine | Human | 14921 | |
| CDK12 (CRK7) | CDK | CMGC | 8bu7 | B | | - | Human | 14913 | |
| CDK12 (CRK7) | CDK | CMGC | 8bu9 | B | | r-roscovitine | Human | 14914 | |
| CDK12 (CRK7) | CDK | CMGC | 8bua | B | | (2~{r})-~{n}-(1~{h}-benzimidazol-2-yl)-2-(3-oxidanylidene-1~{h}-isoindol-2-yl)propanamide | Human | 14932 | |
| CDK12 (CRK7) | CDK | CMGC | 8bub | B | | ~{n}-(5-methyl-2,3-dihydro-1,3-thiazol-2-yl)-3-(5-methylfuran-2-yl)carbonyl-1,3-thiazolidine-4-carboxamide | Human | 14928 | |
| CDK12 (CRK7) | CDK | CMGC | 8buc | B | | 2-(1~{h}-benzimidazol-2-ylsulfanyl)-~{n}-(5-chloranylpyridin-2-yl)ethanamide | Human | 14909 | |
| CDK12 (CRK7) | CDK | CMGC | 8bud | B | | ~{n}-(5-bromanylpyridin-2-yl)-3-(4-oxidanylidenequinazolin-3-yl)propanamide | Human | 14929 | |
| CDK12 (CRK7) | CDK | CMGC | 8bue | B | | ~{n}-(1~{h}-benzimidazol-2-yl)-1-(2-methoxy-5-methyl-phenyl)-5-oxidanylidene-pyrrolidine-3-carboxamide | Human | 14912 | |
| CDK12 (CRK7) | CDK | CMGC | 8buf | B | | 2-(6,7-dihydro-4~{h}-thieno[3,2-c]pyridin-5-ylmethyl)-6,7-dimethoxy-3~{h}-quinazolin-4-one | Human | 14919 | |
| CDK12 (CRK7) | CDK | CMGC | 8bug | B | | 2-[2-[(6-methylpyridin-2-yl)amino]-1,3-thiazol-4-yl]-~{n}-(5-methyl-1,3-thiazol-2-yl)ethanamide | Human | 14935 | |
| CDK12 (CRK7) | CDK | CMGC | 8buh | B | | 6-[[[2-[[(2~{r})-1-oxidanylbutan-2-yl]amino]-9-propan-2-yl-purin-6-yl]amino]methyl]-3-pyridin-2-yl-1~{h}-pyridin-2-one | Human | 14922 | |
| CDK12 (CRK7) | CDK | CMGC | 8bui | B | | (2~{r})-2-[[9-propan-2-yl-6-[(4-pyridin-2-ylphenyl)amino]purin-2-yl]amino]butan-1-ol | Human | 14925 | |
| CDK12 (CRK7) | CDK | CMGC | 8buj | B | | (2~{r})-2-[[6-(octylamino)-9-propan-2-yl-purin-2-yl]amino]butan-1-ol | Human | 14933 | |
| CDK12 (CRK7) | CDK | CMGC | 8buk | B | | (2~{r})-2-[[6-(naphthalen-2-ylmethylamino)-9-propan-2-yl-purin-2-yl]amino]butan-1-ol | Human | 14927 | |
| CDK12 (CRK7) | CDK | CMGC | 8bul | B | | (2~{r})-2-[[6-(3-phenylpropylamino)-9-propan-2-yl-purin-2-yl]amino]butan-1-ol | Human | 14911 | |
| CDK12 (CRK7) | CDK | CMGC | 8bum | B | | (2r)-2-[[6-(5-naphthalen-1-ylpentylamino)-9-propan-2-yl-purin-2-yl]amino]butan-1-ol | Human | 14924 | |
| CDK12 (CRK7) | CDK | CMGC | 8bun | B | | (2~{r})-2-[[6-[(4-phenylphenyl)methylamino]-9-propan-2-yl-purin-2-yl]amino]butan-1-ol | Human | 14916 | |
| CDK12 (CRK7) | CDK | CMGC | 8buo | B | | (2~{r})-2-[[6-[(3-fluoranyl-4-pyridin-2-yl-phenyl)methylamino]-9-propan-2-yl-purin-2-yl]amino]butan-1-ol | Human | 14934 | |
| CDK12 (CRK7) | CDK | CMGC | 8bup | B | | (2~{r})-2-[[6-[3-(3-methylphenyl)propylamino]-9-propan-2-yl-purin-2-yl]amino]butan-1-ol | Human | 14923 | |
| CDK12 (CRK7) | CDK | CMGC | 8buq | B | | (2~{r})-2-[[6-[[1-(3-chlorophenyl)pyrazol-3-yl]methylamino]-9-propan-2-yl-purin-2-yl]amino]butan-1-ol | Human | 14917 | |
| CDK12 (CRK7) | CDK | CMGC | 8bur | B | A | ~{n}-[2-(2-methoxyphenyl)ethyl]-2-[[9-propan-2-yl-6-[(4-pyridin-2-ylphenyl)methylamino]purin-2-yl]amino]ethanamide | Human | 14915 | |
| CDK12 (CRK7) | CDK | CMGC | 8bur | B | B | ~{n}-[2-(2-methoxyphenyl)ethyl]-2-[[9-propan-2-yl-6-[(4-pyridin-2-ylphenyl)methylamino]purin-2-yl]amino]ethanamide | Human | 14920 | |
| CDK12 (CRK7) | CDK | CMGC | 8bus | B | | 1,3-dimethyl-5-[[[9-propan-2-yl-6-[(4-pyridin-2-ylphenyl)methylamino]purin-2-yl]amino]methyl]pyrazole-4-sulfonamide | Human | 14908 | |
| CDK12 (CRK7) | CDK | CMGC | 8but | B | | 2-[[6-[[4-(2-hydroxyethyloxy)phenyl]methylamino]-9-propan-2-yl-purin-2-yl]amino]butan-1-ol | Human | 14936 | |
| CDK12 (CRK7) | CDK | CMGC | 8p81 | A | A | ~{n}-[[5,6-bis(chloranyl)-1~{h}-benzimidazol-2-yl]methyl]-9-(1-methylpyrazol-4-yl)-2-morpholin-4-yl-purin-6-amine | Human | 15062 | |
| CDK12 (CRK7) | CDK | CMGC | 8p81 | A | B | ~{n}-[[5,6-bis(chloranyl)-1~{h}-benzimidazol-2-yl]methyl]-9-(1-methylpyrazol-4-yl)-2-morpholin-4-yl-purin-6-amine | Human | 15061 | |
| CDK13 (CHED) | CDK | CMGC | 5efq | A | | adenosine-5'-diphosphate | Human | 6323 | |
| CDK13 (CHED) | CDK | CMGC | 5efq | C | | adenosine-5'-diphosphate | Human | 6324 | |
| CDK13 (CHED) | CDK | CMGC | 7nxj | A | | n-[4-[(3r)-3-[[5-chloranyl-4-(1h-indol-3-yl)pyrimidin-2-yl]amino]piperidin-1-yl]carbonylphenyl]-4-(dimethylamino)butanamide | Human | 13544 | |
| CDK16 (PCTAIRE1) | CDK | CMGC | 3mtl | A | A | (2z,3e)-2,3'-biindole-2',3(1h,1'h)-dione 3-{o-[(3r)-3,4-dihydroxybutyl]oxime} | Human | 1701 | |
| CDK16 (PCTAIRE1) | CDK | CMGC | 3mtl | A | B | (2z,3e)-2,3'-biindole-2',3(1h,1'h)-dione 3-{o-[(3r)-3,4-dihydroxybutyl]oxime} | Human | 1702 | |
| CDK16 (PCTAIRE1) | CDK | CMGC | 5g6v | A | | 4-[4-({[3-tert-butyl-1-(quinolin-6-yl)-1h-pyrazol-5-yl]carbamoyl}amino)-3-fluorophenoxy]-n-methylpyridine-2-carboxamide | Human | 7273 | |
| CDK16 (PCTAIRE1) | CDK | CMGC | 5g6v | B | | 4-[4-({[3-tert-butyl-1-(quinolin-6-yl)-1h-pyrazol-5-yl]carbamoyl}amino)-3-fluorophenoxy]-n-methylpyridine-2-carboxamide | Human | 7274 | |
| CDK2 | CDK | CMGC | 1aq1 | A | | staurosporine | Human | 4267 | |
| CDK2 | CDK | CMGC | 1b38 | A | | adenosine-5'-triphosphate | Human | 4483 | |
| CDK2 | CDK | CMGC | 1b39 | A | | adenosine-5'-triphosphate | Human | 4407 | |
| CDK2 | CDK | CMGC | 1buh | A | | - | Human | 4178 | |
| CDK2 | CDK | CMGC | 1ckp | A | A | purvalanol b | Human | 4066 | |
| CDK2 | CDK | CMGC | 1ckp | A | B | purvalanol b | Human | 4214 | |
| CDK2 | CDK | CMGC | 1di8 | A | | 4-[3-hydroxyanilino]-6,7-dimethoxyquinazoline | Human | 4577 | |
| CDK2 | CDK | CMGC | 1dm2 | A | A | 4-(5-amino-4-oxo-4h-pyrazol-3-yl)-2-bromo-4,5,6,7-tetrahydro-3ah-pyrrolo[2,3-c]azepin-8-one | Human | 4104 | |
| CDK2 | CDK | CMGC | 1dm2 | A | B | 4-(5-amino-4-oxo-4h-pyrazol-3-yl)-2-bromo-4,5,6,7-tetrahydro-3ah-pyrrolo[2,3-c]azepin-8-one | Human | 4024 | |
| CDK2 | CDK | CMGC | 1e1v | A | | 6-o-cyclohexylmethyl guanine | Human | 3886 | |
| CDK2 | CDK | CMGC | 1e1x | A | | 6-cyclohexylmethyloxy-5-nitroso-pyrimidine-2,4-diamine | Human | 4114 | |
| CDK2 | CDK | CMGC | 1e9h | A | | 2',3-dioxo-1,1',2',3-tetrahydro-2,3'-biindole-5'-sulfonic acid | Human | 4302 | |
| CDK2 | CDK | CMGC | 1e9h | C | | 2',3-dioxo-1,1',2',3-tetrahydro-2,3'-biindole-5'-sulfonic acid | Human | 4570 | |
| CDK2 | CDK | CMGC | 1f5q | A | A | - | Human | 4194 | |
| CDK2 | CDK | CMGC | 1f5q | A | B | - | Human | 4517 | |
| CDK2 | CDK | CMGC | 1f5q | C | A | - | Human | 4281 | |
| CDK2 | CDK | CMGC | 1f5q | C | B | - | Human | 3952 | |
| CDK2 | CDK | CMGC | 1fin | A | | adenosine-5'-triphosphate | Human | 4367 | |
| CDK2 | CDK | CMGC | 1fin | C | | adenosine-5'-triphosphate | Human | 4479 | |
| CDK2 | CDK | CMGC | 1fq1 | B | | adenosine-5'-triphosphate | Human | 4266 | |
| CDK2 | CDK | CMGC | 1fvt | A | | 4-(5-bromo-2-oxo-2h-indol-3-ylazo)-benzenesulfonamide | Human | 4480 | |
| CDK2 | CDK | CMGC | 1fvv | A | | 4-[(7-oxo-7h-thiazolo[5,4-e]indol-8-ylmethyl)-amino]-n-pyridin-2-yl-benzenesulfonamide | Human | 4065 | |
| CDK2 | CDK | CMGC | 1fvv | C | | 4-[(7-oxo-7h-thiazolo[5,4-e]indol-8-ylmethyl)-amino]-n-pyridin-2-yl-benzenesulfonamide | Human | 4461 | |
| CDK2 | CDK | CMGC | 1g5s | A | | 2-[trans-(4-aminocyclohexyl)amino]-6-(benzyl-amino)-9-cyclopentylpurine | Human | 3888 | |
| CDK2 | CDK | CMGC | 1gih | A | | 1-(5-oxo-2,3,5,9b-tetrahydro-1h-pyrrolo[2,1-a]isoindol-9-yl)-3-pyridin-2-yl-urea | Human | 3922 | |
| CDK2 | CDK | CMGC | 1gii | A | | 1-(5-oxo-2,3,5,9b-tetrahydro-1h-pyrrolo[2,1-a]isoindol-9-yl)-3-pyridin-2-yl-urea | Human | 4448 | |
| CDK2 | CDK | CMGC | 1gij | A | | 1-(5-oxo-2,3,5,9b-tetrahydro-1h-pyrrolo[2,1-a]isoindol-9-yl)-3-(5-pyrrolidin-2-yl-1h-pyrazol-3-yl)-urea | Human | 4542 | |
| CDK2 | CDK | CMGC | 1gy3 | A | | adenosine-5'-triphosphate | Human | 3978 | |
| CDK2 | CDK | CMGC | 1gy3 | C | | adenosine-5'-triphosphate | Human | 4445 | |
| CDK2 | CDK | CMGC | 1gz8 | A | A | 1-[(2-amino-6,9-dihydro-1h-purin-6-yl)oxy]-3-methyl-2-butanol | Human | 3981 | |
| CDK2 | CDK | CMGC | 1gz8 | A | B | 1-[(2-amino-6,9-dihydro-1h-purin-6-yl)oxy]-3-methyl-2-butanol | Human | 3956 | |
| CDK2 | CDK | CMGC | 1h00 | A | A | (2s)-1-[4-({6-[(2,6-difluorophenyl)amino]pyrimidin-4-yl}amino)phenoxy]-3-(dimethylamino)propan-2-ol | Human | 4484 | |
| CDK2 | CDK | CMGC | 1h00 | A | B | (2r)-1-[4-({6-[(2,6-difluorophenyl)amino]pyrimidin-4-yl}amino)phenoxy]-3-(dimethylamino)propan-2-ol | Human | 4428 | |
| CDK2 | CDK | CMGC | 1h01 | A | A | (2r)-1-[4-({4-[(2,5-dichlorophenyl)amino]pyrimidin-2-yl}amino)phenoxy]-3-(dimethylamino)propan-2-ol | Human | 3974 | |
| CDK2 | CDK | CMGC | 1h01 | A | B | (2s)-1-[4-({4-[(2,5-dichlorophenyl)amino]pyrimidin-2-yl}amino)phenoxy]-3-(dimethylamino)propan-2-ol | Human | 4561 | |
| CDK2 | CDK | CMGC | 1h07 | A | A | ((2-bromo-4-methylphenyl){6-[(4-{[(2r)-3-(dimethylamino)-2-hydroxypropyl]oxy}phenyl)amino]pyrimidin-4-yl}amino)acetonitrile | Human | 3918 | |
| CDK2 | CDK | CMGC | 1h07 | A | B | ((2-bromo-4-methylphenyl){6-[(4-{[(2s)-3-(dimethylamino)-2-hydroxypropyl]oxy}phenyl)amino]pyrimidin-4-yl}amino)acetonitrile | Human | 3908 | |
| CDK2 | CDK | CMGC | 1h08 | A | A | (2r)-1-{4-[(4-anilino-5-bromopyrimidin-2-yl)amino]phenoxy}-3-(dimethylamino)propan-2-ol | Human | 4220 | |
| CDK2 | CDK | CMGC | 1h08 | A | B | (2s)-1-{4-[(4-anilino-5-bromopyrimidin-2-yl)amino]phenoxy}-3-(dimethylamino)propan-2-ol | Human | 4411 | |
| CDK2 | CDK | CMGC | 1h0v | A | A | 5-{[(2-amino-9h-purin-6-yl)oxy]methyl}-2-pyrrolidinone | Human | 4368 | |
| CDK2 | CDK | CMGC | 1h0v | A | B | 5-{[(2-amino-9h-purin-6-yl)oxy]methyl}-2-pyrrolidinone | Human | 3933 | |
| CDK2 | CDK | CMGC | 1h0w | A | A | 1-amino-6-cyclohex-3-enylmethyloxypurine | Human | 3987 | |
| CDK2 | CDK | CMGC | 1h0w | A | B | 1-amino-6-cyclohex-3-enylmethyloxypurine | Human | 4016 | |
| CDK2 | CDK | CMGC | 1h1p | A | | 6-o-cyclohexylmethyl guanine | Human | 4309 | |
| CDK2 | CDK | CMGC | 1h1p | C | | 6-o-cyclohexylmethyl guanine | Human | 4581 | |
| CDK2 | CDK | CMGC | 1h1q | A | | 2-anilino-6-cyclohexylmethoxypurine | Human | 4195 | |
| CDK2 | CDK | CMGC | 1h1q | C | | 2-anilino-6-cyclohexylmethoxypurine | Human | 4053 | |
| CDK2 | CDK | CMGC | 1h1r | A | A | 6-cyclohexylmethoxy-2-(3'-chloroanilino) purine | Human | 3906 | |
| CDK2 | CDK | CMGC | 1h1r | A | B | 6-cyclohexylmethoxy-2-(3'-chloroanilino) purine | Human | 4494 | |
| CDK2 | CDK | CMGC | 1h1r | C | A | 6-cyclohexylmethoxy-2-(3'-chloroanilino) purine | Human | 3920 | |
| CDK2 | CDK | CMGC | 1h1r | C | B | 6-cyclohexylmethoxy-2-(3'-chloroanilino) purine | Human | 4081 | |
| CDK2 | CDK | CMGC | 1h1s | A | | o6-cyclohexylmethoxy-2-(4'-sulphamoylanilino) purine | Human | 4400 | |
| CDK2 | CDK | CMGC | 1h1s | C | | o6-cyclohexylmethoxy-2-(4'-sulphamoylanilino) purine | Human | 4572 | |
| CDK2 | CDK | CMGC | 1h24 | A | | - | Human | 4199 | |
| CDK2 | CDK | CMGC | 1h24 | C | | - | Human | 4296 | |
| CDK2 | CDK | CMGC | 1h25 | A | | - | Human | 4273 | |
| CDK2 | CDK | CMGC | 1h25 | C | | - | Human | 4112 | |
| CDK2 | CDK | CMGC | 1h26 | A | | - | Human | 4122 | |
| CDK2 | CDK | CMGC | 1h26 | C | | - | Human | 4179 | |
| CDK2 | CDK | CMGC | 1h27 | A | | - | Human | 4116 | |
| CDK2 | CDK | CMGC | 1h27 | C | | - | Human | 4030 | |
| CDK2 | CDK | CMGC | 1h28 | A | | - | Human | 4169 | |
| CDK2 | CDK | CMGC | 1h28 | C | | - | Human | 4351 | |
| CDK2 | CDK | CMGC | 1hck | A | A | adenosine-5'-triphosphate | Human | 3878 | |
| CDK2 | CDK | CMGC | 1hck | A | B | adenosine-5'-triphosphate | Human | 4416 | |
| CDK2 | CDK | CMGC | 1hcl | A | A | - | Human | 4545 | |
| CDK2 | CDK | CMGC | 1hcl | A | B | - | Human | 4540 | |
| CDK2 | CDK | CMGC | 1jst | A | | adenosine-5'-triphosphate | Human | 4455 | |
| CDK2 | CDK | CMGC | 1jst | C | | adenosine-5'-triphosphate | Human | 4356 | |
| CDK2 | CDK | CMGC | 1jsu | A | | - | Human | 4146 | |
| CDK2 | CDK | CMGC | 1jsv | A | | 4-[(6-amino-4-pyrimidinyl)amino]benzenesulfonamide | Human | 4171 | |
| CDK2 | CDK | CMGC | 1jvp | P | 1 | 3-pyridin-4-yl-2,4-dihydroindeno[1,2-c]pyrazole | Human | 3919 | |
| CDK2 | CDK | CMGC | 1jvp | P | 2 | 3-pyridin-4-yl-2,4-dihydroindeno[1,2-c]pyrazole | Human | 4097 | |
| CDK2 | CDK | CMGC | 1ke5 | A | | n-methyl-4-{[(2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]amino}benzenesulfonamide | Human | 4376 | |
| CDK2 | CDK | CMGC | 1ke6 | A | | n-methyl-{4-[2-(7-oxo-6,7-dihydro-8h-[1,3]thiazolo[5,4-e]indol-8-ylidene)hydrazino]phenyl}methanesulfonamide | Human | 4219 | |
| CDK2 | CDK | CMGC | 1ke7 | A | | 3-{[(2,2-dioxido-1,3-dihydro-2-benzothien-5-yl)amino]methylene}-5-(1,3-oxazol-5-yl)-1,3-dihydro-2h-indol-2-one | Human | 4295 | |
| CDK2 | CDK | CMGC | 1ke8 | A | | 4-{[(2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]amino}-n-(1,3-thiazol-2-yl)benzenesulfonamide | Human | 4048 | |
| CDK2 | CDK | CMGC | 1ke9 | A | | 3-{[4-([amino(imino)methyl]aminosulfonyl)anilino]methylene}-2-oxo-2,3-dihydro-1h-indole | Human | 4250 | |
| CDK2 | CDK | CMGC | 1ogu | A | A | 4-{[4-amino-6-(cyclohexylmethoxy)-5-nitrosopyrimidin-2-yl]amino}benzamide | Human | 3965 | |
| CDK2 | CDK | CMGC | 1ogu | A | B | 4-{[4-amino-6-(cyclohexylmethoxy)-5-nitrosopyrimidin-2-yl]amino}benzamide | Human | 3935 | |
| CDK2 | CDK | CMGC | 1ogu | C | A | 4-{[4-amino-6-(cyclohexylmethoxy)-5-nitrosopyrimidin-2-yl]amino}benzamide | Human | 3964 | |
| CDK2 | CDK | CMGC | 1ogu | C | B | 4-{[4-amino-6-(cyclohexylmethoxy)-5-nitrosopyrimidin-2-yl]amino}benzamide | Human | 4560 | |
| CDK2 | CDK | CMGC | 1oi9 | A | A | 6-cyclohexylmethyloxy-2-(4'-hydroxyanilino)purine | Human | 4033 | |
| CDK2 | CDK | CMGC | 1oi9 | A | B | 6-cyclohexylmethyloxy-2-(4'-hydroxyanilino)purine | Human | 4492 | |
| CDK2 | CDK | CMGC | 1oi9 | C | A | 6-cyclohexylmethyloxy-2-(4'-hydroxyanilino)purine | Human | 4571 | |
| CDK2 | CDK | CMGC | 1oi9 | C | B | 6-cyclohexylmethyloxy-2-(4'-hydroxyanilino)purine | Human | 4036 | |
| CDK2 | CDK | CMGC | 1oiq | A | | n-[4-(2-methylimidazo[1,2-a]pyridin-3-yl)-2-pyrimidinyl]acetamide | Human | 4379 | |
| CDK2 | CDK | CMGC | 1oir | A | | 1-(dimethylamino)-3-(4-{{4-(2-methylimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]amino}phenoxy)propan-2-ol | Human | 4389 | |
| CDK2 | CDK | CMGC | 1oit | A | | 4-[(4-imidazo[1,2-a]pyridin-3-ylpyrimidin-2-yl)amino]benzenesulfonamide | Human | 4025 | |
| CDK2 | CDK | CMGC | 1oiu | A | A | 3-(6-cyclohexylmethoxy-9h-purin-2-ylamino)-benzenesulfonamide | Human | 4110 | |
| CDK2 | CDK | CMGC | 1oiu | A | B | 3-(6-cyclohexylmethoxy-9h-purin-2-ylamino)-benzenesulfonamide | Human | 4556 | |
| CDK2 | CDK | CMGC | 1oiu | C | A | 3-(6-cyclohexylmethoxy-9h-purin-2-ylamino)-benzenesulfonamide | Human | 4524 | |
| CDK2 | CDK | CMGC | 1oiu | C | B | 3-(6-cyclohexylmethoxy-9h-purin-2-ylamino)-benzenesulfonamide | Human | 4049 | |
| CDK2 | CDK | CMGC | 1oiy | A | A | 4-(6-cyclohexylmethoxy-9h-purin-2-ylamino)--benzamide | Human | 4225 | |
| CDK2 | CDK | CMGC | 1oiy | A | B | 4-(6-cyclohexylmethoxy-9h-purin-2-ylamino)--benzamide | Human | 3945 | |
| CDK2 | CDK | CMGC | 1oiy | C | A | 4-(6-cyclohexylmethoxy-9h-purin-2-ylamino)--benzamide | Human | 4465 | |
| CDK2 | CDK | CMGC | 1oiy | C | B | 4-(6-cyclohexylmethoxy-9h-purin-2-ylamino)--benzamide | Human | 4245 | |
| CDK2 | CDK | CMGC | 1okv | A | | - | Human | 3921 | |
| CDK2 | CDK | CMGC | 1okv | C | | - | Human | 4093 | |
| CDK2 | CDK | CMGC | 1okw | A | | - | Human | 4314 | |
| CDK2 | CDK | CMGC | 1okw | C | | - | Human | 3896 | |
| CDK2 | CDK | CMGC | 1ol1 | A | | - | Human | 4429 | |
| CDK2 | CDK | CMGC | 1ol1 | C | | - | Human | 3951 | |
| CDK2 | CDK | CMGC | 1ol2 | A | | - | Human | 4305 | |
| CDK2 | CDK | CMGC | 1ol2 | C | | - | Human | 4497 | |
| CDK2 | CDK | CMGC | 1p2a | A | | 5-[(2-aminoethyl)amino]-6-fluoro-3-(1h-pyrrol-2-yl)benzo[cd]indol-2(1h)-one | Human | 4422 | |
| CDK2 | CDK | CMGC | 1p5e | A | | 4,5,6,7-tetrabromobenzotriazole | Human | 4090 | |
| CDK2 | CDK | CMGC | 1p5e | C | | 4,5,6,7-tetrabromobenzotriazole | Human | 4434 | |
| CDK2 | CDK | CMGC | 1pf8 | A | | (3z)-3-(1h-imidazol-5-ylmethylene)-5-methoxy-1h-indol-2(3h)-one | Human | 3861 | |
| CDK2 | CDK | CMGC | 1pkd | A | | 7-hydroxystaurosporine | Human | 4170 | |
| CDK2 | CDK | CMGC | 1pkd | C | | 7-hydroxystaurosporine | Human | 3973 | |
| CDK2 | CDK | CMGC | 1pw2 | A | | - | Human | 4432 | |
| CDK2 | CDK | CMGC | 1pxi | A | A | 4-(2,5-dichlorothien-3-yl)pyrimidin-2-amine | Human | 4381 | |
| CDK2 | CDK | CMGC | 1pxi | A | B | - | Human | 3924 | |
| CDK2 | CDK | CMGC | 1pxj | A | A | 4-(2,4-dimethyl-1,3-thiazol-5-yl)pyrimidin-2-amine | Human | 3927 | |
| CDK2 | CDK | CMGC | 1pxj | A | B | - | Human | 3911 | |
| CDK2 | CDK | CMGC | 1pxk | A | A | n-[4-(2,4-dimethyl-1,3-thiazol-5-yl)pyrimidin-2-yl]-n'-hydroxyimidoformamide | Human | 3915 | |
| CDK2 | CDK | CMGC | 1pxk | A | B | - | Human | 3980 | |
| CDK2 | CDK | CMGC | 1pxl | A | A | 4-(2,4-dimethyl-1,3-thiazol-5-yl)-n-[4-(trifluoromethyl)phenyl]pyrimidin-2-amine | Human | 4233 | |
| CDK2 | CDK | CMGC | 1pxl | A | B | - | Human | 4074 | |
| CDK2 | CDK | CMGC | 1pxm | A | A | 3-[4-(2,4-dimethyl-thiazol-5-yl)-pyrimidin-2-ylamino]-phenol | Human | 3944 | |
| CDK2 | CDK | CMGC | 1pxm | A | B | - | Human | 3936 | |
| CDK2 | CDK | CMGC | 1pxn | A | A | 4-[4-(4-methyl-2-methylamino-thiazol-5-yl)-pyrimidin-2-ylamino]-phenol | Human | 4383 | |
| CDK2 | CDK | CMGC | 1pxn | A | B | - | Human | 4172 | |
| CDK2 | CDK | CMGC | 1pxo | A | A | [4-(2-amino-4-methyl-thiazol-5-yl)-pyrimidin-2-yl]-(3-nitro-phenyl)-amine | Human | 4512 | |
| CDK2 | CDK | CMGC | 1pxo | A | B | - | Human | 3860 | |
| CDK2 | CDK | CMGC | 1pxo | A | C | [4-(2-amino-4-methyl-thiazol-5-yl)-pyrimidin-2-yl]-(3-nitro-phenyl)-amine | Human | 4546 | |
| CDK2 | CDK | CMGC | 1pxo | A | D | [4-(2-amino-4-methyl-thiazol-5-yl)-pyrimidin-2-yl]-(3-nitro-phenyl)-amine | Human | 4167 | |
| CDK2 | CDK | CMGC | 1pxp | A | A | n-[4-(2,4-dimethyl-thiazol-5-yl)-pyrimidin-2-yl]-n',n'-dimethyl-benzene-1,4-diamine | Human | 4316 | |
| CDK2 | CDK | CMGC | 1pxp | A | B | - | Human | 3943 | |
| CDK2 | CDK | CMGC | 1pye | A | | [2-amino-6-(2,6-difluoro-benzoyl)-imidazo[1,2-a]pyridin-3-yl]-phenyl-methanone | Human | 4284 | |
| CDK2 | CDK | CMGC | 1qmz | A | | adenosine-5'-triphosphate | Human | 4242 | |
| CDK2 | CDK | CMGC | 1qmz | C | | adenosine-5'-triphosphate | Human | 4527 | |
| CDK2 | CDK | CMGC | 1r78 | A | A | 4-((3r,4s,5r)-4-amino-3,5-dihydroxy-hex-1-ynyl)-5-fluoro-3-[1-(3-methoxy-1h-pyrrol-2-yl)-meth-(z)-ylidene]-1,3-dihydro-indol-2-one | Human | 4253 | |
| CDK2 | CDK | CMGC | 1r78 | A | B | 4-((3r,4s,5r)-4-amino-3,5-dihydroxy-hex-1-ynyl)-5-fluoro-3-[1-(3-methoxy-1h-pyrrol-2-yl)-meth-(z)-ylidene]-1,3-dihydro-indol-2-one | Human | 4249 | |
| CDK2 | CDK | CMGC | 1urc | A | A | - | Human | 4334 | |
| CDK2 | CDK | CMGC | 1urc | A | B | - | Human | 4010 | |
| CDK2 | CDK | CMGC | 1urc | C | A | - | Human | 4006 | |
| CDK2 | CDK | CMGC | 1urc | C | B | - | Human | 3937 | |
| CDK2 | CDK | CMGC | 1urw | A | A | 2-[4-(n-(3-dimethylaminopropyl)sulphamoyl)anilino]- | Human | 4054 | |
| CDK2 | CDK | CMGC | 1urw | A | B | 2-[4-(n-(3-dimethylaminopropyl)sulphamoyl)anilino]- | Human | 4196 | |
| CDK2 | CDK | CMGC | 1v1k | A | A | (2r)-1-(dimethylamino)-3-{4-[(6-{[2-fluoro-5-(trifluoromethyl)phenyl]amino}pyrimidin-4-yl)amino]phenoxy}propan-2-ol | Human | 4189 | |
| CDK2 | CDK | CMGC | 1v1k | A | B | (2r)-1-(dimethylamino)-3-{4-[(6-{[2-fluoro-5-(trifluoromethyl)phenyl]amino}pyrimidin-4-yl)amino]phenoxy}propan-2-ol | Human | 3928 | |
| CDK2 | CDK | CMGC | 1vyw | A | | n-(3-cyclopropyl-1h-pyrazol-5-yl)-2-(2-naphthyl)acetamide | Human | 3992 | |
| CDK2 | CDK | CMGC | 1vyw | C | | n-(3-cyclopropyl-1h-pyrazol-5-yl)-2-(2-naphthyl)acetamide | Human | 4133 | |
| CDK2 | CDK | CMGC | 1vyz | A | | n-(5-cyclopropyl-1h-pyrazol-3-yl)benzamide | Human | 4325 | |
| CDK2 | CDK | CMGC | 1w0x | C | A | olomoucine | Human | 4537 | |
| CDK2 | CDK | CMGC | 1w0x | C | B | olomoucine | Human | 4478 | |
| CDK2 | CDK | CMGC | 1w8c | A | A | 6-(cyclohexylmethoxy)-8-isopropyl-9h-purin-2-amine | Human | 4332 | |
| CDK2 | CDK | CMGC | 1w8c | A | B | 6-(cyclohexylmethoxy)-8-isopropyl-9h-purin-2-amine | Human | 4197 | |
| CDK2 | CDK | CMGC | 1w98 | A | | - | Human | 4013 | |
| CDK2 | CDK | CMGC | 1wcc | A | A | 2-amino-6-chloropyrazine | Human | 4394 | |
| CDK2 | CDK | CMGC | 1wcc | A | B | 2-amino-6-chloropyrazine | Human | 3897 | |
| CDK2 | CDK | CMGC | 1y8y | A | | (5-chloropyrazolo[1,5-a]pyrimidin-7-yl)-(4-methanesulfonylphenyl)amine | Human | 3914 | |
| CDK2 | CDK | CMGC | 1y91 | A | | 4-[5-(trans-4-aminocyclohexylamino)-3-isopropylpyrazolo[1,5-a]pyrimidin-7-ylamino]-n,n-dimethylbenzenesulfonamide | Human | 4505 | |
| CDK2 | CDK | CMGC | 1ykr | A | | 4-{[6-(2,6-dichlorobenzoyl)imidazo[1,2-a]pyridin-2-yl]amino}benzenesulfonamide | Human | 4578 | |
| CDK2 | CDK | CMGC | 2a0c | X | A | 2-{[(2-{[(1r)-1-(hydroxymethyl)propyl]amino}-9-isopropyl-9h-purin-6-yl)amino]methyl}phenol | Human | 4157 | |
| CDK2 | CDK | CMGC | 2a0c | X | B | 2-{[(2-{[(1r)-1-(hydroxymethyl)propyl]amino}-9-isopropyl-9h-purin-6-yl)amino]methyl}phenol | Human | 3868 | |
| CDK2 | CDK | CMGC | 2a4l | A | | r-roscovitine | Human | 4238 | |
| CDK2 | CDK | CMGC | 2b52 | A | | 1-(3-(2,4-dimethylthiazol-5-yl)-4-oxo-2,4-dihydroindeno[1,2-c]pyrazol-5-yl)-3-(4-methylpiperazin-1-yl)urea | Human | 3997 | |
| CDK2 | CDK | CMGC | 2b53 | A | | 6-(3-aminophenyl)-n-(tert-butyl)-2-(trifluoromethyl)quinazolin-4-amine | Human | 3875 | |
| CDK2 | CDK | CMGC | 2b54 | A | | 6-(3,4-dihydroxybenzyl)-3-ethyl-1-(2,4,6-trichlorophenyl)-1h-pyrazolo[3,4-d]pyrimidin-4(5h)-one | Human | 4292 | |
| CDK2 | CDK | CMGC | 2b55 | A | | 2-(4-(aminomethyl)piperidin-1-yl)-n-(3_cyclohexyl-4-oxo-2,4-dihydroindeno[1,2-c]pyrazol-5-yl)acetamide | Human | 4216 | |
| CDK2 | CDK | CMGC | 2bhe | A | | (2z)-5'-bromo-2,3'-biindole-2',3(1h,1'h)-dione ammoniate | Human | 4184 | |
| CDK2 | CDK | CMGC | 2bhh | A | | (2e,3s)-3-hydroxy-5'-[(4-hydroxypiperidin-1-yl)sulfonyl]-3-methyl-1,3-dihydro-2,3'-biindol-2'(1'h)-one | Human | 4417 | |
| CDK2 | CDK | CMGC | 2bkz | A | | 1-[4-(aminosulfonyl)phenyl]-1,6-dihydropyrazolo[3,4-e]indazole-3-carboxamide | Human | 3942 | |
| CDK2 | CDK | CMGC | 2bkz | C | | 1-[4-(aminosulfonyl)phenyl]-1,6-dihydropyrazolo[3,4-e]indazole-3-carboxamide | Human | 4555 | |
| CDK2 | CDK | CMGC | 2bpm | A | | (2s)-n-[(3z)-5-cyclopropyl-3h-pyrazol-3-ylidene]-2-[4-(2-oxoimidazolidin-1-yl)phenyl]propanamide | Human | 4042 | |
| CDK2 | CDK | CMGC | 2bpm | C | | (2s)-n-[(3z)-5-cyclopropyl-3h-pyrazol-3-ylidene]-2-[4-(2-oxoimidazolidin-1-yl)phenyl]propanamide | Human | 4128 | |
| CDK2 | CDK | CMGC | 2btr | A | | n-(5-isopropyl-thiazol-2-yl)-2-pyridin-3-yl-acetamide | Human | 3998 | |
| CDK2 | CDK | CMGC | 2bts | A | | 4-[(5-isopropyl-1,3-thiazol-2-yl)amino]benzenesulfonamide | Human | 4443 | |
| CDK2 | CDK | CMGC | 2c4g | A | | (3z)-5-acetyl-3-(benzoylimino)-3,6-dihydropyrrolo[3,4-c]pyrazol-5-ium | Human | 4088 | |
| CDK2 | CDK | CMGC | 2c4g | C | | (3z)-5-acetyl-3-(benzoylimino)-3,6-dihydropyrrolo[3,4-c]pyrazol-5-ium | Human | 4453 | |
| CDK2 | CDK | CMGC | 2c5n | A | A | n-[4-(2,4-dimethyl-thiazol-5-yl)-pyrimidin-2-yl]-n',n'-dimethyl-benzene-1,4-diamine | Human | 4063 | |
| CDK2 | CDK | CMGC | 2c5n | A | B | n-[4-(2,4-dimethyl-thiazol-5-yl)-pyrimidin-2-yl]-n',n'-dimethyl-benzene-1,4-diamine | Human | 4223 | |
| CDK2 | CDK | CMGC | 2c5n | C | A | n-[4-(2,4-dimethyl-thiazol-5-yl)-pyrimidin-2-yl]-n',n'-dimethyl-benzene-1,4-diamine | Human | 4161 | |
| CDK2 | CDK | CMGC | 2c5n | C | B | n-[4-(2,4-dimethyl-thiazol-5-yl)-pyrimidin-2-yl]-n',n'-dimethyl-benzene-1,4-diamine | Human | 3903 | |
| CDK2 | CDK | CMGC | 2c5o | A | A | 4-(2,4-dimethyl-1,3-thiazol-5-yl)pyrimidin-2-amine | Human | 4388 | |
| CDK2 | CDK | CMGC | 2c5o | A | B | 4-(2,4-dimethyl-1,3-thiazol-5-yl)pyrimidin-2-amine | Human | 4440 | |
| CDK2 | CDK | CMGC | 2c5o | C | A | 4-(2,4-dimethyl-1,3-thiazol-5-yl)pyrimidin-2-amine | Human | 4414 | |
| CDK2 | CDK | CMGC | 2c5o | C | B | 4-(2,4-dimethyl-1,3-thiazol-5-yl)pyrimidin-2-amine | Human | 4050 | |
| CDK2 | CDK | CMGC | 2c5v | A | A | 4-(2,4-dimethyl-1,3-thiazol-5-yl)-n-[4-(trifluoromethyl)phenyl]pyrimidin-2-amine | Human | 4012 | |
| CDK2 | CDK | CMGC | 2c5v | A | B | 4-(2,4-dimethyl-1,3-thiazol-5-yl)-n-[4-(trifluoromethyl)phenyl]pyrimidin-2-amine | Human | 4338 | |
| CDK2 | CDK | CMGC | 2c5v | C | A | 4-(2,4-dimethyl-1,3-thiazol-5-yl)-n-[4-(trifluoromethyl)phenyl]pyrimidin-2-amine | Human | 4384 | |
| CDK2 | CDK | CMGC | 2c5v | C | B | 4-(2,4-dimethyl-1,3-thiazol-5-yl)-n-[4-(trifluoromethyl)phenyl]pyrimidin-2-amine | Human | 4209 | |
| CDK2 | CDK | CMGC | 2c5x | A | A | hydroxy(oxo)(3-{[(2z)-4-[3-(1h-1,2,4-triazol-1-ylmethyl)phenyl]pyrimidin-2(5h)-ylidene]amino}phenyl)ammonium | Human | 4312 | |
| CDK2 | CDK | CMGC | 2c5x | A | B | hydroxy(oxo)(3-{[(2z)-4-[3-(1h-1,2,4-triazol-1-ylmethyl)phenyl]pyrimidin-2(5h)-ylidene]amino}phenyl)ammonium | Human | 3892 | |
| CDK2 | CDK | CMGC | 2c5x | C | A | hydroxy(oxo)(3-{[(2z)-4-[3-(1h-1,2,4-triazol-1-ylmethyl)phenyl]pyrimidin-2(5h)-ylidene]amino}phenyl)ammonium | Human | 4466 | |
| CDK2 | CDK | CMGC | 2c5x | C | B | hydroxy(oxo)(3-{[(2z)-4-[3-(1h-1,2,4-triazol-1-ylmethyl)phenyl]pyrimidin-2(5h)-ylidene]amino}phenyl)ammonium | Human | 4418 | |
| CDK2 | CDK | CMGC | 2c5y | A | A | hydroxy(oxo)(3-{[(2z)-4-[3-(1h-1,2,4-triazol-1-ylmethyl)phenyl]pyrimidin-2(5h)-ylidene]amino}phenyl)ammonium | Human | 6785 | |
| CDK2 | CDK | CMGC | 2c5y | A | B | hydroxy(oxo)(3-{[(2z)-4-[3-(1h-1,2,4-triazol-1-ylmethyl)phenyl]pyrimidin-2(5h)-ylidene]amino}phenyl)ammonium | Human | 6777 | |
| CDK2 | CDK | CMGC | 2c68 | A | | (5z)-5-(3-bromocyclohexa-2,5-dien-1-ylidene)-n-(pyridin-4-ylmethyl)-1,5-dihydropyrazolo[1,5-a]pyrimidin-7-amine | Human | 6776 | |
| CDK2 | CDK | CMGC | 2c69 | A | | (5z)-5-(3-bromocyclohexa-2,5-dien-1-ylidene)-n-(pyridin-4-ylmethyl)-1,5-dihydro[1,2,4]triazolo[1,5-a]pyrimidin-7-amine | Human | 6775 | |
| CDK2 | CDK | CMGC | 2c6i | A | | 4-{[5-(cyclohexylmethoxy)[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]amino}benzenesulfonamide | Human | 6774 | |
| CDK2 | CDK | CMGC | 2c6k | A | | 4-{[5-(cyclohexylamino)[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]amino}benzenesulfonamide | Human | 6773 | |
| CDK2 | CDK | CMGC | 2c6l | A | | 4-({5-[(4-aminocyclohexyl)amino][1,2,4]triazolo[1,5-a]pyrimidin-7-yl}amino)benzenesulfonamide | Human | 6779 | |
| CDK2 | CDK | CMGC | 2c6m | A | | 4-{[5-(cyclohexyloxy)[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]amino}benzenesulfonamide | Human | 6782 | |
| CDK2 | CDK | CMGC | 2c6o | A | | o6-cyclohexylmethoxy-2-(4'-sulphamoylanilino) purine | Human | 6783 | |
| CDK2 | CDK | CMGC | 2c6t | A | | 4-{[5-(cyclohexyloxy)[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]amino}benzenesulfonamide | Human | 4371 | |
| CDK2 | CDK | CMGC | 2c6t | C | | 4-{[5-(cyclohexyloxy)[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]amino}benzenesulfonamide | Human | 3994 | |
| CDK2 | CDK | CMGC | 2cch | A | A | adenosine-5'-triphosphate | Human | 4303 | |
| CDK2 | CDK | CMGC | 2cch | A | B | adenosine-5'-triphosphate | Human | 4553 | |
| CDK2 | CDK | CMGC | 2cch | A | C | - | Human | 4566 | |
| CDK2 | CDK | CMGC | 2cch | C | A | adenosine-5'-triphosphate | Human | 3932 | |
| CDK2 | CDK | CMGC | 2cch | C | B | adenosine-5'-triphosphate | Human | 4000 | |
| CDK2 | CDK | CMGC | 2cch | C | C | - | Human | 4431 | |
| CDK2 | CDK | CMGC | 2cci | A | | adenosine-5'-triphosphate | Human | 4373 | |
| CDK2 | CDK | CMGC | 2cci | C | | adenosine-5'-triphosphate | Human | 4532 | |
| CDK2 | CDK | CMGC | 2cjm | A | | adenosine-5'-triphosphate | Human | 4406 | |
| CDK2 | CDK | CMGC | 2cjm | C | | adenosine-5'-triphosphate | Human | 4126 | |
| CDK2 | CDK | CMGC | 2clx | A | A | 4-[(e)-(3,5-diamino-1h-pyrazol-4-yl)diazenyl]phenol | Human | 3909 | |
| CDK2 | CDK | CMGC | 2clx | A | B | 4-[(e)-(3,5-diamino-1h-pyrazol-4-yl)diazenyl]phenol | Human | 3880 | |
| CDK2 | CDK | CMGC | 2ds1 | A | | (13r,15s)-13-methyl-16-oxa-8,9,12,22,24-pentaazahexacyclo[15.6.2.16,9.1,12,15.0,2,7.0,21,25]heptacosa-1(24),2,4,6,17(25),18,20-heptaene-23,26-dione | Human | 4513 | |
| CDK2 | CDK | CMGC | 2duv | A | | 2-(3,4-dihydroxyphenyl)-8-(1,1-dioxidoisothiazolidin-2-yl)-3-hydroxy-6-methyl-4h-chromen-4-one | Human | 4193 | |
| CDK2 | CDK | CMGC | 2exm | A | | n-(3-methylbut-2-en-1-yl)-9h-purin-6-amine | Human | 4055 | |
| CDK2 | CDK | CMGC | 2fvd | A | | (4-amino-2-{[1-(methylsulfonyl)piperidin-4-yl]amino}pyrimidin-5-yl)(2,3-difluoro-6-methoxyphenyl)methanone | Human | 4408 | |
| CDK2 | CDK | CMGC | 2g9x | A | | 3-({2-[(4-{[6-(cyclohexylmethoxy)-9h-purin-2-yl]amino}phenyl)sulfonyl]ethyl}amino)propan-1-ol | Human | 3883 | |
| CDK2 | CDK | CMGC | 2g9x | C | | 3-({2-[(4-{[6-(cyclohexylmethoxy)-9h-purin-2-yl]amino}phenyl)sulfonyl]ethyl}amino)propan-1-ol | Human | 4082 | |
| CDK2 | CDK | CMGC | 2i40 | A | A | 5-[5,6-bis(methyloxy)-1h-benzimidazol-1-yl]-3-{[1-(2-chlorophenyl)ethyl]oxy}-2-thiophenecarboxamide | Human | 4363 | |
| CDK2 | CDK | CMGC | 2i40 | A | B | 5-[5,6-bis(methyloxy)-1h-benzimidazol-1-yl]-3-{[1-(2-chlorophenyl)ethyl]oxy}-2-thiophenecarboxamide | Human | 4470 | |
| CDK2 | CDK | CMGC | 2i40 | C | A | 5-[5,6-bis(methyloxy)-1h-benzimidazol-1-yl]-3-{[1-(2-chlorophenyl)ethyl]oxy}-2-thiophenecarboxamide | Human | 4222 | |
| CDK2 | CDK | CMGC | 2i40 | C | B | 5-[5,6-bis(methyloxy)-1h-benzimidazol-1-yl]-3-{[1-(2-chlorophenyl)ethyl]oxy}-2-thiophenecarboxamide | Human | 4043 | |
| CDK2 | CDK | CMGC | 2iw6 | A | | [(2-chloro-5-methylphenyl){6-[(4-{[(2r)-3-(dimethylamino)-2-hydroxypropyl]oxy}phenyl)amino]pyrimidin-4-yl}amino]acetonitrile | Human | 4019 | |
| CDK2 | CDK | CMGC | 2iw6 | C | | [(2-chloro-5-methylphenyl){6-[(4-{[(2r)-3-(dimethylamino)-2-hydroxypropyl]oxy}phenyl)amino]pyrimidin-4-yl}amino]acetonitrile | Human | 4108 | |
| CDK2 | CDK | CMGC | 2iw8 | A | A | o6-cyclohexylmethoxy-2-(4'-sulphamoylanilino) purine | Human | 4142 | |
| CDK2 | CDK | CMGC | 2iw8 | A | B | o6-cyclohexylmethoxy-2-(4'-sulphamoylanilino) purine | Human | 4377 | |
| CDK2 | CDK | CMGC | 2iw8 | C | A | o6-cyclohexylmethoxy-2-(4'-sulphamoylanilino) purine | Human | 4294 | |
| CDK2 | CDK | CMGC | 2iw8 | C | B | o6-cyclohexylmethoxy-2-(4'-sulphamoylanilino) purine | Human | 4350 | |
| CDK2 | CDK | CMGC | 2iw9 | A | A | o6-cyclohexylmethoxy-2-(4'-sulphamoylanilino) purine | Human | 4174 | |
| CDK2 | CDK | CMGC | 2iw9 | A | B | o6-cyclohexylmethoxy-2-(4'-sulphamoylanilino) purine | Human | 3955 | |
| CDK2 | CDK | CMGC | 2iw9 | C | A | o6-cyclohexylmethoxy-2-(4'-sulphamoylanilino) purine | Human | 4218 | |
| CDK2 | CDK | CMGC | 2iw9 | C | B | o6-cyclohexylmethoxy-2-(4'-sulphamoylanilino) purine | Human | 3858 | |
| CDK2 | CDK | CMGC | 2j9m | A | A | 6-bromo-13-thia-2,4,8,12,19-pentaazatricyclo[12.3.1.1~3,7~]nonadeca-1(18),3(19),4,6,14,16-hexaene 13,13-dioxide | Human | 4154 | |
| CDK2 | CDK | CMGC | 2j9m | A | B | 6-bromo-13-thia-2,4,8,12,19-pentaazatricyclo[12.3.1.1~3,7~]nonadeca-1(18),3(19),4,6,14,16-hexaene 13,13-dioxide | Human | 4246 | |
| CDK2 | CDK | CMGC | 2jgz | A | | - | Human | 4117 | |
| CDK2 | CDK | CMGC | 2r3f | A | A | 5-(2,3-dichlorophenyl)-n-(pyridin-4-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine | Human | 4175 | |
| CDK2 | CDK | CMGC | 2r3f | A | B | 5-(2,3-dichlorophenyl)-n-(pyridin-4-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine | Human | 4291 | |
| CDK2 | CDK | CMGC | 2r3g | A | A | 6-(2-fluorophenyl)-n-(pyridin-3-ylmethyl)imidazo[1,2-a]pyrazin-8-amine | Human | 4276 | |
| CDK2 | CDK | CMGC | 2r3g | A | B | 6-(2-fluorophenyl)-n-(pyridin-3-ylmethyl)imidazo[1,2-a]pyrazin-8-amine | Human | 3923 | |
| CDK2 | CDK | CMGC | 2r3h | A | A | 3-methyl-n-(pyridin-4-ylmethyl)imidazo[1,2-a]pyrazin-8-amine | Human | 4152 | |
| CDK2 | CDK | CMGC | 2r3h | A | B | 3-methyl-n-(pyridin-4-ylmethyl)imidazo[1,2-a]pyrazin-8-amine | Human | 3970 | |
| CDK2 | CDK | CMGC | 2r3i | A | A | 5-(2-fluorophenyl)-n-(pyridin-4-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine | Human | 4135 | |
| CDK2 | CDK | CMGC | 2r3i | A | B | 5-(2-fluorophenyl)-n-(pyridin-4-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine | Human | 4059 | |
| CDK2 | CDK | CMGC | 2r3i | A | C | - | Human | 4317 | |
| CDK2 | CDK | CMGC | 2r3j | A | A | 3-bromo-5-phenyl-n-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine | Human | 4185 | |
| CDK2 | CDK | CMGC | 2r3j | A | B | 3-bromo-5-phenyl-n-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine | Human | 4544 | |
| CDK2 | CDK | CMGC | 2r3k | A | A | 3-bromo-5-phenyl-n-(pyrimidin-5-ylmethyl)pyrazolo[1,5-a]pyridin-7-amine | Human | 3953 | |
| CDK2 | CDK | CMGC | 2r3k | A | B | 3-bromo-5-phenyl-n-(pyrimidin-5-ylmethyl)pyrazolo[1,5-a]pyridin-7-amine | Human | 3876 | |
| CDK2 | CDK | CMGC | 2r3k | A | C | 3-bromo-5-phenyl-n-(pyrimidin-5-ylmethyl)pyrazolo[1,5-a]pyridin-7-amine | Human | 4022 | |
| CDK2 | CDK | CMGC | 2r3l | A | A | 3-bromo-6-phenyl-n-(pyrimidin-5-ylmethyl)imidazo[1,2-a]pyridin-8-amine | Human | 4200 | |
| CDK2 | CDK | CMGC | 2r3l | A | B | 3-bromo-6-phenyl-n-(pyrimidin-5-ylmethyl)imidazo[1,2-a]pyridin-8-amine | Human | 4085 | |
| CDK2 | CDK | CMGC | 2r3l | A | C | 3-bromo-6-phenyl-n-(pyrimidin-5-ylmethyl)imidazo[1,2-a]pyridin-8-amine | Human | 4496 | |
| CDK2 | CDK | CMGC | 2r3m | A | A | n-((2-aminopyrimidin-5-yl)methyl)-5-(2,6-difluorophenyl)-3-ethylpyrazolo[1,5-a]pyrimidin-7-amine | Human | 4286 | |
| CDK2 | CDK | CMGC | 2r3m | A | B | n-((2-aminopyrimidin-5-yl)methyl)-5-(2,6-difluorophenyl)-3-ethylpyrazolo[1,5-a]pyrimidin-7-amine | Human | 4576 | |
| CDK2 | CDK | CMGC | 2r3n | A | A | 3-cyclopropyl-5-phenyl-n-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine | Human | 4101 | |
| CDK2 | CDK | CMGC | 2r3n | A | B | 3-cyclopropyl-5-phenyl-n-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine | Human | 4046 | |
| CDK2 | CDK | CMGC | 2r3o | A | A | (5-phenyl-7-(pyridin-3-ylmethylamino)pyrazolo[1,5-a]pyrimidin-3-yl)methanol | Human | 4147 | |
| CDK2 | CDK | CMGC | 2r3o | A | B | (5-phenyl-7-(pyridin-3-ylmethylamino)pyrazolo[1,5-a]pyrimidin-3-yl)methanol | Human | 4354 | |
| CDK2 | CDK | CMGC | 2r3o | A | C | (5-phenyl-7-(pyridin-3-ylmethylamino)pyrazolo[1,5-a]pyrimidin-3-yl)methanol | Human | 4229 | |
| CDK2 | CDK | CMGC | 2r3p | A | A | 5-(2,3-dichlorophenyl)-n-(pyridin-4-ylmethyl)-3-thiocyanatopyrazolo[1,5-a]pyrimidin-7-amine | Human | 4176 | |
| CDK2 | CDK | CMGC | 2r3p | A | B | 5-(2,3-dichlorophenyl)-n-(pyridin-4-ylmethyl)-3-thiocyanatopyrazolo[1,5-a]pyrimidin-7-amine | Human | 4392 | |
| CDK2 | CDK | CMGC | 2r3q | A | A | 3-((3-bromo-5-o-tolylpyrazolo[1,5-a]pyrimidin-7-ylamino)methyl)pyridine 1-oxide | Human | 4038 | |
| CDK2 | CDK | CMGC | 2r3q | A | B | 3-((3-bromo-5-o-tolylpyrazolo[1,5-a]pyrimidin-7-ylamino)methyl)pyridine 1-oxide | Human | 4459 | |
| CDK2 | CDK | CMGC | 2r3q | A | C | 3-((3-bromo-5-o-tolylpyrazolo[1,5-a]pyrimidin-7-ylamino)methyl)pyridine 1-oxide | Human | 3976 | |
| CDK2 | CDK | CMGC | 2r3r | A | A | 3-bromo-5-phenyl-n-(pyridin-4-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine | Human | 4040 | |
| CDK2 | CDK | CMGC | 2r3r | A | B | 3-bromo-5-phenyl-n-(pyridin-4-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine | Human | 4215 | |
| CDK2 | CDK | CMGC | 2r64 | A | | n-[5-(1,1-dioxidoisothiazolidin-2-yl)-1h-indazol-3-yl]-2-(4-piperidin-1-ylphenyl)acetamide | Human | 4425 | |
| CDK2 | CDK | CMGC | 2uue | A | | 4-methyl-5-{(2e)-2-[(4-morpholin-4-ylphenyl)imino]-2,5-dihydropyrimidin-4-yl}-1,3-thiazol-2-amine | Human | 4515 | |
| CDK2 | CDK | CMGC | 2uue | C | | 4-methyl-5-{(2e)-2-[(4-morpholin-4-ylphenyl)imino]-2,5-dihydropyrimidin-4-yl}-1,3-thiazol-2-amine | Human | 4321 | |
| CDK2 | CDK | CMGC | 2uzb | A | C | 4-{5-[(z)-(2-imino-4-oxo-1,3-thiazolidin-5-ylidene)methyl]-2-furyl}-n-methylbenzenesulfonamide | Human | 4099 | |
| CDK2 | CDK | CMGC | 2uzb | A | D | 4-{5-[(z)-(2-imino-4-oxo-1,3-thiazolidin-5-ylidene)methyl]-2-furyl}-n-methylbenzenesulfonamide | Human | 3866 | |
| CDK2 | CDK | CMGC | 2uzb | C | C | 4-{5-[(z)-(2-imino-4-oxo-1,3-thiazolidin-5-ylidene)methyl]-2-furyl}-n-methylbenzenesulfonamide | Human | 4045 | |
| CDK2 | CDK | CMGC | 2uzb | C | D | 4-{5-[(z)-(2-imino-4-oxo-1,3-thiazolidin-5-ylidene)methyl]-2-furyl}-n-methylbenzenesulfonamide | Human | 4502 | |
| CDK2 | CDK | CMGC | 2uzd | A | | 4-{5-[(z)-(2-imino-4-oxo-1,3-thiazolidin-5-ylidene)methyl]furan-2-yl}benzenesulfonamide | Human | 3877 | |
| CDK2 | CDK | CMGC | 2uzd | C | | 4-{5-[(z)-(2-imino-4-oxo-1,3-thiazolidin-5-ylidene)methyl]furan-2-yl}benzenesulfonamide | Human | 3900 | |
| CDK2 | CDK | CMGC | 2uze | A | | 4-{5-[(z)-(2-imino-4-oxo-1,3-thiazolidin-5-ylidene)methyl]furan-2-yl}benzoic acid | Human | 3949 | |
| CDK2 | CDK | CMGC | 2uze | C | | 4-{5-[(z)-(2-imino-4-oxo-1,3-thiazolidin-5-ylidene)methyl]furan-2-yl}benzoic acid | Human | 4071 | |
| CDK2 | CDK | CMGC | 2uzl | A | | 4-{5-[(z)-(2-imino-4-oxo-1,3-thiazolidin-5-ylidene)methyl]furan-2-yl}-2-(trifluoromethyl)benzenesulfonamide | Human | 3917 | |
| CDK2 | CDK | CMGC | 2uzl | C | | 4-{5-[(z)-(2-imino-4-oxo-1,3-thiazolidin-5-ylidene)methyl]furan-2-yl}-2-(trifluoromethyl)benzenesulfonamide | Human | 4106 | |
| CDK2 | CDK | CMGC | 2uzn | A | | 4-{5-[(1z)-1-(2-imino-4-oxo-1,3-thiazolidin-5-ylidene)ethyl]-2-furyl}benzenesulfonamide | Human | 4064 | |
| CDK2 | CDK | CMGC | 2uzo | A | | 4-{5-[(z)-(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]furan-2-yl}benzenesulfonamide | Human | 3862 | |
| CDK2 | CDK | CMGC | 2v0d | A | | 2-imino-5-(1-pyridin-2-yl-meth-(e)-ylidene)-1,3-thiazolidin-4-one | Human | 4327 | |
| CDK2 | CDK | CMGC | 2v22 | A | | - | Human | 4077 | |
| CDK2 | CDK | CMGC | 2v22 | C | | - | Human | 4255 | |
| CDK2 | CDK | CMGC | 2vta | A | | 1h-indazole | Human | 4118 | |
| CDK2 | CDK | CMGC | 2vth | A | | 5-hydroxynaphthalene-1-sulfonamide | Human | 4274 | |
| CDK2 | CDK | CMGC | 2vti | A | | n-(4-sulfamoylphenyl)-1h-indazole-3-carboxamide | Human | 4177 | |
| CDK2 | CDK | CMGC | 2vtj | A | | 4-[(6-chloropyrazin-2-yl)amino]benzenesulfonamide | Human | 3959 | |
| CDK2 | CDK | CMGC | 2vtl | A | | n-phenyl-1h-pyrazole-3-carboxamide | Human | 3870 | |
| CDK2 | CDK | CMGC | 2vtm | A | | pyrazolo[1,5-a]pyrimidine-3-carbonitrile | Human | 4283 | |
| CDK2 | CDK | CMGC | 2vtn | A | | 4-(acetylamino)-n-(4-fluorophenyl)-1h-pyrazole-3-carboxamide | Human | 4027 | |
| CDK2 | CDK | CMGC | 2vto | A | A | n-(4-fluorophenyl)-4-[(phenylcarbonyl)amino]-1h-pyrazole-3-carboxamide | Human | 4421 | |
| CDK2 | CDK | CMGC | 2vto | A | B | n-(4-fluorophenyl)-4-[(phenylcarbonyl)amino]-1h-pyrazole-3-carboxamide | Human | 3946 | |
| CDK2 | CDK | CMGC | 2vtp | A | A | {[(2,6-difluorophenyl)carbonyl]amino}-n-(4-fluorophenyl)-1h-pyrazole-3-carboxamide | Human | 4511 | |
| CDK2 | CDK | CMGC | 2vtp | A | B | {[(2,6-difluorophenyl)carbonyl]amino}-n-(4-fluorophenyl)-1h-pyrazole-3-carboxamide | Human | 4401 | |
| CDK2 | CDK | CMGC | 2vtq | A | | {[(2,6-difluorophenyl)carbonyl]amino}-n-piperidin-4-yl-1h-pyrazole-3-carboxamide | Human | 3891 | |
| CDK2 | CDK | CMGC | 2vtr | A | A | 5-chloro-7-[(1-methylethyl)amino]pyrazolo[1,5-a]pyrimidine-3-carbonitrile | Human | 4391 | |
| CDK2 | CDK | CMGC | 2vtr | A | B | 5-chloro-7-[(1-methylethyl)amino]pyrazolo[1,5-a]pyrimidine-3-carbonitrile | Human | 3907 | |
| CDK2 | CDK | CMGC | 2vts | A | | 5-[(4-aminocyclohexyl)amino]-7-(propan-2-ylamino)pyrazolo[1,5-a]pyrimidine-3-carbonitrile | Human | 4300 | |
| CDK2 | CDK | CMGC | 2vtt | A | | 4-{[(2,6-difluorophenyl)carbonyl]amino}-n-[(3s)-piperidin-3-yl]-1h-pyrazole-3-carboxamide | Human | 4100 | |
| CDK2 | CDK | CMGC | 2vu3 | A | A | 4-{[(2,6-dichlorophenyl)carbonyl]amino}-n-piperidin-4-yl-1h-pyrazole-3-carboxamide | Human | 4582 | |
| CDK2 | CDK | CMGC | 2vu3 | A | B | 4-{[(2,6-dichlorophenyl)carbonyl]amino}-n-piperidin-4-yl-1h-pyrazole-3-carboxamide | Human | 3884 | |
| CDK2 | CDK | CMGC | 2vv9 | A | A | 2-{4-[4-({4-[2-methyl-1-(1-methylethyl)-1h-imidazol-5-yl]pyrimidin-2-yl}amino)phenyl]piperazin-1-yl}-2-oxoethanol | Human | 3989 | |
| CDK2 | CDK | CMGC | 2vv9 | A | B | 2-{4-[4-({4-[2-methyl-1-(1-methylethyl)-1h-imidazol-5-yl]pyrimidin-2-yl}amino)phenyl]piperazin-1-yl}-2-oxoethanol | Human | 3881 | |
| CDK2 | CDK | CMGC | 2w05 | A | A | n-(2-methoxyethyl)-4-({4-[2-methyl-1-(1-methylethyl)-1h-imidazol-5-yl]pyrimidin-2-yl}amino)benzenesulfonamide | Human | 4547 | |
| CDK2 | CDK | CMGC | 2w05 | A | B | n-(2-methoxyethyl)-4-({4-[2-methyl-1-(1-methylethyl)-1h-imidazol-5-yl]pyrimidin-2-yl}amino)benzenesulfonamide | Human | 4256 | |
| CDK2 | CDK | CMGC | 2w06 | A | | 4-{[4-(1-cyclopropyl-2-methyl-1h-imidazol-5-yl)pyrimidin-2-yl]amino}-n-methylbenzenesulfonamide | Human | 3982 | |
| CDK2 | CDK | CMGC | 2w17 | A | A | n-(4-{[(3s)-3-(dimethylamino)pyrrolidin-1-yl]carbonyl}phenyl)-5-fluoro-4-[2-methyl-1-(1-methylethyl)-1h-imidazol-5-yl]pyrimidin-2-amine | Human | 3968 | |
| CDK2 | CDK | CMGC | 2w17 | A | B | n-(4-{[(3s)-3-(dimethylamino)pyrrolidin-1-yl]carbonyl}phenyl)-5-fluoro-4-[2-methyl-1-(1-methylethyl)-1h-imidazol-5-yl]pyrimidin-2-amine | Human | 4165 | |
| CDK2 | CDK | CMGC | 2w1h | A | | n-[3-(1h-benzimidazol-2-yl)-1h-pyrazol-4-yl]benzamide | Human | 4228 | |
| CDK2 | CDK | CMGC | 2wev | A | A | [4-(2-amino-4-methyl-thiazol-5-yl)-pyrimidin-2-yl]-(3-nitro-phenyl)-amine | Human | 4067 | |
| CDK2 | CDK | CMGC | 2wev | A | B | [4-(2-amino-4-methyl-thiazol-5-yl)-pyrimidin-2-yl]-(3-nitro-phenyl)-amine | Human | 4580 | |
| CDK2 | CDK | CMGC | 2wev | A | C | [4-(2-amino-4-methyl-thiazol-5-yl)-pyrimidin-2-yl]-(3-nitro-phenyl)-amine | Human | 4007 | |
| CDK2 | CDK | CMGC | 2wev | C | A | [4-(2-amino-4-methyl-thiazol-5-yl)-pyrimidin-2-yl]-(3-nitro-phenyl)-amine | Human | 4503 | |
| CDK2 | CDK | CMGC | 2wev | C | B | [4-(2-amino-4-methyl-thiazol-5-yl)-pyrimidin-2-yl]-(3-nitro-phenyl)-amine | Human | 3859 | |
| CDK2 | CDK | CMGC | 2wev | C | C | [4-(2-amino-4-methyl-thiazol-5-yl)-pyrimidin-2-yl]-(3-nitro-phenyl)-amine | Human | 4288 | |
| CDK2 | CDK | CMGC | 2wfy | A | A | - | Human | 4324 | |
| CDK2 | CDK | CMGC | 2wfy | A | B | - | Human | 4426 | |
| CDK2 | CDK | CMGC | 2wfy | C | A | - | Human | 4329 | |
| CDK2 | CDK | CMGC | 2wfy | C | B | - | Human | 4096 | |
| CDK2 | CDK | CMGC | 2whb | A | A | - | Human | 4471 | |
| CDK2 | CDK | CMGC | 2whb | A | B | - | Human | 4457 | |
| CDK2 | CDK | CMGC | 2whb | C | A | - | Human | 4132 | |
| CDK2 | CDK | CMGC | 2whb | C | B | - | Human | 4352 | |
| CDK2 | CDK | CMGC | 2wih | A | | n,1,4,4-tetramethyl-8-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4,5-dihydro-1h-pyrazolo[4,3-h]quinazoline-3-carboxamide | Human | 4163 | |
| CDK2 | CDK | CMGC | 2wih | C | | n,1,4,4-tetramethyl-8-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4,5-dihydro-1h-pyrazolo[4,3-h]quinazoline-3-carboxamide | Human | 4119 | |
| CDK2 | CDK | CMGC | 2wip | A | | 1-methyl-8-(phenylamino)-4,5-dihydro-1h-pyrazolo[4,3-h]quinazoline-3-carboxylic acid | Human | 4520 | |
| CDK2 | CDK | CMGC | 2wip | C | | 1-methyl-8-(phenylamino)-4,5-dihydro-1h-pyrazolo[4,3-h]quinazoline-3-carboxylic acid | Human | 4190 | |
| CDK2 | CDK | CMGC | 2wma | A | | - | Human | 4435 | |
| CDK2 | CDK | CMGC | 2wma | C | | - | Human | 4410 | |
| CDK2 | CDK | CMGC | 2wmb | A | | - | Human | 4060 | |
| CDK2 | CDK | CMGC | 2wmb | C | | - | Human | 4474 | |
| CDK2 | CDK | CMGC | 2wpa | A | | n-{6,6-dimethyl-5-[(1-methylpiperidin-4-yl)carbonyl]-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl}-3-methylbutanamide | Human | 4399 | |
| CDK2 | CDK | CMGC | 2wpa | C | | n-{6,6-dimethyl-5-[(1-methylpiperidin-4-yl)carbonyl]-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl}-3-methylbutanamide | Human | 4162 | |
| CDK2 | CDK | CMGC | 2wxv | A | | n,1-dimethyl-8-{[1-(methylsulfonyl)piperidin-4-yl]amino}-1h-pyrazolo[4,3-h]quinazoline-3-carboxamide | Human | 4318 | |
| CDK2 | CDK | CMGC | 2wxv | C | | n,1-dimethyl-8-{[1-(methylsulfonyl)piperidin-4-yl]amino}-1h-pyrazolo[4,3-h]quinazoline-3-carboxamide | Human | 4504 | |
| CDK2 | CDK | CMGC | 2x1n | A | A | 2-methyl-n-[(1z)-3-nitrocyclohexa-2,4-dien-1-ylidene]-4,5-dihydro[1,3]thiazolo[4,5-h]quinazolin-8-amine | Human | 4579 | |
| CDK2 | CDK | CMGC | 2x1n | A | B | 2-methyl-n-[(1z)-3-nitrocyclohexa-2,4-dien-1-ylidene]-4,5-dihydro[1,3]thiazolo[4,5-h]quinazolin-8-amine | Human | 4078 | |
| CDK2 | CDK | CMGC | 2x1n | C | A | 2-methyl-n-[(1z)-3-nitrocyclohexa-2,4-dien-1-ylidene]-4,5-dihydro[1,3]thiazolo[4,5-h]quinazolin-8-amine | Human | 3991 | |
| CDK2 | CDK | CMGC | 2x1n | C | B | 2-methyl-n-[(1z)-3-nitrocyclohexa-2,4-dien-1-ylidene]-4,5-dihydro[1,3]thiazolo[4,5-h]quinazolin-8-amine | Human | 4062 | |
| CDK2 | CDK | CMGC | 2xmy | A | A | 4-[4-(3,4-dimethyl-2-oxo-2,3-dihydro-thiazol-5-yl)-pyrimidin-2-ylamino]-n-(2-methoxy-ethyl)-benzenesulfonamide | Human | 4526 | |
| CDK2 | CDK | CMGC | 2xmy | A | B | 4-[4-(3,4-dimethyl-2-oxo-2,3-dihydro-thiazol-5-yl)-pyrimidin-2-ylamino]-n-(2-methoxy-ethyl)-benzenesulfonamide | Human | 3985 | |
| CDK2 | CDK | CMGC | 2xnb | A | A | 3,4-dimethyl-5-(2-{[(1z)-4-piperazin-1-ylcyclohexa-2,4-dien-1-ylidene]amino}pyrimidin-4-yl)-1,3-thiazol-2(3h)-one | Human | 4217 | |
| CDK2 | CDK | CMGC | 2xnb | A | B | 3,4-dimethyl-5-(2-{[(1z)-4-piperazin-1-ylcyclohexa-2,4-dien-1-ylidene]amino}pyrimidin-4-yl)-1,3-thiazol-2(3h)-one | Human | 4034 | |
| CDK2 | CDK | CMGC | 3bht | A | A | 4-(4-methoxy-1h-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine | Human | 3950 | |
| CDK2 | CDK | CMGC | 3bht | A | B | 4-(4-methoxy-1h-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine | Human | 4491 | |
| CDK2 | CDK | CMGC | 3bht | C | A | 4-(4-methoxy-1h-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine | Human | 4151 | |
| CDK2 | CDK | CMGC | 3bht | C | B | 4-(4-methoxy-1h-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine | Human | 3889 | |
| CDK2 | CDK | CMGC | 3bhu | A | A | 4-(4-propoxy-1h-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine | Human | 4105 | |
| CDK2 | CDK | CMGC | 3bhu | A | B | 4-(4-propoxy-1h-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine | Human | 4446 | |
| CDK2 | CDK | CMGC | 3bhu | C | A | 4-(4-propoxy-1h-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine | Human | 4087 | |
| CDK2 | CDK | CMGC | 3bhu | C | B | 4-(4-propoxy-1h-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine | Human | 4464 | |
| CDK2 | CDK | CMGC | 3bhv | A | A | 9-amino-5-(2-aminopyrimidin-4-yl)pyrido[3',2':4,5]pyrrolo[1,2-c]pyrimidin-4-ol | Human | 4531 | |
| CDK2 | CDK | CMGC | 3bhv | A | B | 9-amino-5-(2-aminopyrimidin-4-yl)pyrido[3',2':4,5]pyrrolo[1,2-c]pyrimidin-4-ol | Human | 4001 | |
| CDK2 | CDK | CMGC | 3bhv | C | A | 9-amino-5-(2-aminopyrimidin-4-yl)pyrido[3',2':4,5]pyrrolo[1,2-c]pyrimidin-4-ol | Human | 4353 | |
| CDK2 | CDK | CMGC | 3bhv | C | B | 9-amino-5-(2-aminopyrimidin-4-yl)pyrido[3',2':4,5]pyrrolo[1,2-c]pyrimidin-4-ol | Human | 4529 | |
| CDK2 | CDK | CMGC | 3ddp | A | A | (2r)-2-({9-(1-methylethyl)-6-[(4-pyridin-2-ylbenzyl)amino]-9h-purin-2-yl}amino)butan-1-ol | Human | 6781 | |
| CDK2 | CDK | CMGC | 3ddp | A | B | (2r)-2-({9-(1-methylethyl)-6-[(4-pyridin-2-ylbenzyl)amino]-9h-purin-2-yl}amino)butan-1-ol | Human | 6780 | |
| CDK2 | CDK | CMGC | 3ddp | C | A | (2r)-2-({9-(1-methylethyl)-6-[(4-pyridin-2-ylbenzyl)amino]-9h-purin-2-yl}amino)butan-1-ol | Human | 6784 | |
| CDK2 | CDK | CMGC | 3ddp | C | B | (2r)-2-({9-(1-methylethyl)-6-[(4-pyridin-2-ylbenzyl)amino]-9h-purin-2-yl}amino)butan-1-ol | Human | 6778 | |
| CDK2 | CDK | CMGC | 3ddq | A | A | r-roscovitine | Human | 4477 | |
| CDK2 | CDK | CMGC | 3ddq | A | B | r-roscovitine | Human | 4269 | |
| CDK2 | CDK | CMGC | 3ddq | C | A | r-roscovitine | Human | 4364 | |
| CDK2 | CDK | CMGC | 3ddq | C | B | r-roscovitine | Human | 4289 | |
| CDK2 | CDK | CMGC | 3dog | A | A | (2r)-2-{[4-(benzylamino)-8-(1-methylethyl)pyrazolo[1,5-a][1,3,5]triazin-2-yl]amino}butan-1-ol | Human | 4541 | |
| CDK2 | CDK | CMGC | 3dog | A | B | (2r)-2-{[4-(benzylamino)-8-(1-methylethyl)pyrazolo[1,5-a][1,3,5]triazin-2-yl]amino}butan-1-ol | Human | 4365 | |
| CDK2 | CDK | CMGC | 3dog | C | A | (2r)-2-{[4-(benzylamino)-8-(1-methylethyl)pyrazolo[1,5-a][1,3,5]triazin-2-yl]amino}butan-1-ol | Human | 4382 | |
| CDK2 | CDK | CMGC | 3dog | C | B | (2r)-2-{[4-(benzylamino)-8-(1-methylethyl)pyrazolo[1,5-a][1,3,5]triazin-2-yl]amino}butan-1-ol | Human | 4121 | |
| CDK2 | CDK | CMGC | 3eid | A | A | (2s)-1-(dimethylamino)-3-(4-{[4-(6-morpholin-4-ylpyrazolo[1,5-b]pyridazin-3-yl)pyrimidin-2-yl]amino}phenoxy)propan-2-ol | Human | 4386 | |
| CDK2 | CDK | CMGC | 3eid | A | B | (2s)-1-(dimethylamino)-3-(4-{[4-(6-morpholin-4-ylpyrazolo[1,5-b]pyridazin-3-yl)pyrimidin-2-yl]amino}phenoxy)propan-2-ol | Human | 4424 | |
| CDK2 | CDK | CMGC | 3eid | C | A | - | Human | 4072 | |
| CDK2 | CDK | CMGC | 3eid | C | B | - | Human | 4467 | |
| CDK2 | CDK | CMGC | 3ej1 | A | | n-cyclopropyl-4-pyrazolo[1,5-b]pyridazin-3-ylpyrimidin-2-amine | Human | 4168 | |
| CDK2 | CDK | CMGC | 3ej1 | C | | n-cyclopropyl-4-pyrazolo[1,5-b]pyridazin-3-ylpyrimidin-2-amine | Human | 4092 | |
| CDK2 | CDK | CMGC | 3eoc | A | | 5-methyl-7-phenyl-n-(3,4,5-trimethoxyphenyl)imidazo[5,1-f][1,2,4]triazin-2-amine | Human | 4390 | |
| CDK2 | CDK | CMGC | 3eoc | C | | 5-methyl-7-phenyl-n-(3,4,5-trimethoxyphenyl)imidazo[5,1-f][1,2,4]triazin-2-amine | Human | 3969 | |
| CDK2 | CDK | CMGC | 3ezr | A | | 3-methoxy-4-{3-[4-(4-methylpiperazin-1-yl)-1h-benzimidazol-2-yl]-1h-indazol-6-yl}aniline | Human | 4475 | |
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