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Searching for structures with analogs of
Golvatinib
.
Search results (8 entries covering 3 PDB structures)
#
Kinase
Family
Group
PDB
Chain
(Alternate) Model
Orthosteric ligand
Organism
Details
Similarity (MFP)
File
MET
Met
TK
5dg5
B
B
n-(2,5-difluoro-4-{[2-(1-methyl-1h-pyrazol-4-yl)pyridin-4-yl]oxy}phenyl)-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
Human
7036
0.49
MET
Met
TK
4mxc
A
B
n-(3-fluoro-4-{[2-({3-[(methylsulfonyl)methyl]phenyl}amino)pyrimidin-4-yl]oxy}phenyl)-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
Human
3025
0.40
MET
Met
TK
5dg5
A
A
n-(2,5-difluoro-4-{[2-(1-methyl-1h-pyrazol-4-yl)pyridin-4-yl]oxy}phenyl)-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
Human
7037
0.49
EPHA2 (EphA2)
Eph
TK
5ia5
A
B
golvatinib
Human
7183
1.00
EPHA2 (EphA2)
Eph
TK
5ia5
A
A
golvatinib
Human
7192
1.00
MET
Met
TK
5dg5
B
A
n-(2,5-difluoro-4-{[2-(1-methyl-1h-pyrazol-4-yl)pyridin-4-yl]oxy}phenyl)-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
Human
7035
0.49
MET
Met
TK
4mxc
A
A
n-(3-fluoro-4-{[2-({3-[(methylsulfonyl)methyl]phenyl}amino)pyrimidin-4-yl]oxy}phenyl)-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
Human
3033
0.40
MET
Met
TK
5dg5
A
B
n-(2,5-difluoro-4-{[2-(1-methyl-1h-pyrazol-4-yl)pyridin-4-yl]oxy}phenyl)-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
Human
7034
0.49
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Golvatinib
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