| FGFR1 | FGFR | TK | 5vnd | A | B | n-{2-[(6-{[(2,6-dichloro-3,5-dimethoxyphenyl)carbamoyl](methyl)amino}pyrimidin-4-yl)amino]-5-(4-ethylpiperazin-1-yl)phenyl}propanamide | Human | 7648 | 0.77 | |
| FGFR1 | FGFR | TK | 3tt0 | B | B | 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-(6-{[4-(4-ethylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)-1-methylurea | Human | 3581 | 1.00 | |
| FGFR1 | FGFR | TK | 5vnd | A | A | n-{2-[(6-{[(2,6-dichloro-3,5-dimethoxyphenyl)carbamoyl](methyl)amino}pyrimidin-4-yl)amino]-5-(4-ethylpiperazin-1-yl)phenyl}propanamide | Human | 7646 | 0.77 | |
| EGFR | EGFR | TK | 4r5s | A | | n-[4-({[(2,6-dichloro-3,5-dimethoxyphenyl)carbamoyl](6-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino}methyl)phenyl]propanamide | Human | 775 | 0.67 | |
| EGFR | EGFR | TK | 5gtz | A | B | n-[5-[[5-chloranyl-4-[(2-propan-2-ylsulfonylphenyl)amino]pyrimidin-2-yl]amino]-2-(4-ethylpiperazin-1-yl)-4-methoxy-phenyl]prop-2-enamide | Human | 8361 | 0.41 | |
| EGFR | EGFR | TK | 5gtz | A | A | n-[5-[[5-chloranyl-4-[(2-propan-2-ylsulfonylphenyl)amino]pyrimidin-2-yl]amino]-2-(4-ethylpiperazin-1-yl)-4-methoxy-phenyl]prop-2-enamide | Human | 8365 | 0.41 | |
| FGFR1 | FGFR | TK | 5vnd | B | A | n-{2-[(6-{[(2,6-dichloro-3,5-dimethoxyphenyl)carbamoyl](methyl)amino}pyrimidin-4-yl)amino]-5-(4-ethylpiperazin-1-yl)phenyl}propanamide | Human | 7647 | 0.77 | |
| FGFR1 | FGFR | TK | 6p69 | A | A | n-{2-[(6-{[(2,6-dichloro-3,5-dimethoxyphenyl)carbamoyl][3-(4-methylpiperazin-1-yl)propyl]amino}pyrimidin-4-yl)amino]phenyl}prop-2-enamide | Human | 11333 | 0.49 | |
| FGFR1 | FGFR | TK | 6p68 | C | | n-{3-[(6-{[(2,6-dichloro-3,5-dimethoxyphenyl)carbamoyl](methyl)amino}pyrimidin-4-yl)amino]-1-(2-hydroxyethyl)-1h-pyrazol-4-yl}prop-2-enamide | Human | 11332 | 0.52 | |
| FGFR1 | FGFR | TK | 6p69 | B | B | n-{2-[(6-{[(2,6-dichloro-3,5-dimethoxyphenyl)carbamoyl][3-(4-methylpiperazin-1-yl)propyl]amino}pyrimidin-4-yl)amino]phenyl}prop-2-enamide | Human | 11335 | 0.49 | |
| FGFR1 | FGFR | TK | 6p68 | B | | n-{3-[(6-{[(2,6-dichloro-3,5-dimethoxyphenyl)carbamoyl](methyl)amino}pyrimidin-4-yl)amino]-1-(2-hydroxyethyl)-1h-pyrazol-4-yl}prop-2-enamide | Human | 11334 | 0.52 | |
| FGFR1 | FGFR | TK | 6p68 | A | | n-{3-[(6-{[(2,6-dichloro-3,5-dimethoxyphenyl)carbamoyl](methyl)amino}pyrimidin-4-yl)amino]-1-(2-hydroxyethyl)-1h-pyrazol-4-yl}prop-2-enamide | Human | 11336 | 0.52 | |
| FGFR1 | FGFR | TK | 6p69 | A | B | n-{2-[(6-{[(2,6-dichloro-3,5-dimethoxyphenyl)carbamoyl][3-(4-methylpiperazin-1-yl)propyl]amino}pyrimidin-4-yl)amino]phenyl}prop-2-enamide | Human | 11330 | 0.49 | |
| FGFR4 | FGFR | TK | 4r6v | A | | n-[4-({[(2,6-dichloro-3,5-dimethoxyphenyl)carbamoyl](6-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino}methyl)phenyl]propanamide | Human | 931 | 0.67 | |
| FGFR1 | FGFR | TK | 3tt0 | B | A | 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-(6-{[4-(4-ethylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)-1-methylurea | Human | 3547 | 1.00 | |
| FGFR1 | FGFR | TK | 5vnd | B | B | n-{2-[(6-{[(2,6-dichloro-3,5-dimethoxyphenyl)carbamoyl](methyl)amino}pyrimidin-4-yl)amino]-5-(4-ethylpiperazin-1-yl)phenyl}propanamide | Human | 7645 | 0.77 | |
| FGFR1 | FGFR | TK | 3tt0 | A | A | 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-(6-{[4-(4-ethylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)-1-methylurea | Human | 3567 | 1.00 | |
| FGFR1 | FGFR | TK | 3tt0 | A | B | 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-(6-{[4-(4-ethylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)-1-methylurea | Human | 3538 | 1.00 | |
| FGFR1 | FGFR | TK | 6p69 | B | A | n-{2-[(6-{[(2,6-dichloro-3,5-dimethoxyphenyl)carbamoyl][3-(4-methylpiperazin-1-yl)propyl]amino}pyrimidin-4-yl)amino]phenyl}prop-2-enamide | Human | 11331 | 0.49 | |
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