Searching for structures with analogs of Itacitinib.

Search results (21 entries covering 8 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetailsSimilarity (MFP)File
BMP2K (BIKE)NAKOther4w9xAbaricitinibHuman32730.56
JAK2JakATK6wtnAA(3r)-3-cyclopentyl-3-[4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl]propanenitrileHuman135380.43
JAK2JakATK6wtoABbaricitinibHuman135390.56
JAK2JakATK6wtnAB(3r)-3-cyclopentyl-3-[4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl]propanenitrileHuman135400.43
JAK2JakATK6vglA(3r)-3-cyclopentyl-3-[4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl]propanenitrileHuman132230.43
JAK2JakATK6vglD(3r)-3-cyclopentyl-3-[4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl]propanenitrileHuman132200.43
JAK2JakATK6vglC(3r)-3-cyclopentyl-3-[4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl]propanenitrileHuman132210.43
JAK2JakATK6vglB(3r)-3-cyclopentyl-3-[4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl]propanenitrileHuman132220.43
JAK2JakATK6vnkB(3r)-3-cyclopentyl-3-[4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl]propanenitrileHuman132950.43
JAK2JakATK6vn8AbaricitinibHuman132910.56
JAK2JakATK6vn8BbaricitinibHuman133010.56
JAK2JakATK6vnkD(3r)-3-cyclopentyl-3-[4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl]propanenitrileHuman132920.43
JAK2JakATK6vnkA(3r)-3-cyclopentyl-3-[4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl]propanenitrileHuman132930.43
JAK2JakATK6vnkC(3r)-3-cyclopentyl-3-[4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl]propanenitrileHuman133040.43
JAK2JakATK6vsnD(3s)-3-cyclopentyl-3-[4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl]propanenitrileHuman133430.43
JAK2JakATK6vsnC(3s)-3-cyclopentyl-3-[4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl]propanenitrileHuman133500.43
JAK2JakATK6vsnB(3s)-3-cyclopentyl-3-[4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl]propanenitrileHuman133560.43
JAK2JakATK6vsnA(3s)-3-cyclopentyl-3-[4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl]propanenitrileHuman133530.43
JAK2JakATK6wtpAAtert-butyl 4-[(4-{1-[3-(cyanomethyl)-1-(ethylsulfonyl)azetidin-3-yl]-1h-pyrazol-4-yl}-7h-pyrrolo[2,3-d]pyrimidin-2-yl)amino]benzoateHuman135410.43
JAK2JakATK6wtpABtert-butyl 4-[(4-{1-[3-(cyanomethyl)-1-(ethylsulfonyl)azetidin-3-yl]-1h-pyrazol-4-yl}-7h-pyrrolo[2,3-d]pyrimidin-2-yl)amino]benzoateHuman135420.43
JAK2JakATK6wtoAAbaricitinibHuman135360.56