Searching for structures with analogs of Lestaurtinib.

Search results (168 entries covering 85 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetailsSimilarity (MFP)File
ITKTecTK1snuBstaurosporineHuman330.59
ITKTecTK1sm2BstaurosporineHuman730.59
ITKTecTK1snuAstaurosporineHuman820.59
PRKAA1 (AMPKa1)CAMKLCAMK4rerAstaurosporineHuman1210.59
PRKAA2 (AMPKa2)CAMKLCAMK4cffCstaurosporineHuman1900.59
PRKAA2 (AMPKa2)CAMKLCAMK4cfeCstaurosporineHuman1920.59
IKBKB (IKKb)IKKOther4kikABk-252aHuman2880.72
IKBKB (IKKb)IKKOther4kikAAk-252aHuman2900.72
IKBKB (IKKb)IKKOther4kikBBk-252aHuman2930.72
IKBKB (IKKb)IKKOther4kikBAk-252aHuman2950.72
EPHB4 (EphB4)EphTK2yn8BstaurosporineHuman3490.59
EPHB4 (EphB4)EphTK3zewBAstaurosporineHuman3510.59
EPHB4 (EphB4)EphTK2yn8AstaurosporineHuman3520.59
EPHB4 (EphB4)EphTK3zewBBstaurosporineHuman3570.59
EPHB4 (EphB4)EphTK3zewAAstaurosporineHuman3730.59
JAK3JakATK1yvjAB1,2,3,4-tetrahydrogen-staurosporineHuman4510.50
JAK3JakATK1yvjAA1,2,3,4-tetrahydrogen-staurosporineHuman4600.50
PKN1PKNAGC4otgAAlestaurtinibHuman5480.69
PKN1PKNAGC4otgABlestaurtinibHuman5490.69
MKNK2 (MNK2)MAPKAPKCAMK2hw7AstaurosporineHuman7640.59
ABL1AblTK2hz4B1,2,3,4-tetrahydrogen-staurosporineHuman10580.50
SYKSykTK1xbcAAstaurosporineHuman11650.59
MAP2K6STE7STE3fmeAstaurosporineHuman12310.59
SYKSykTK1xbcABstaurosporineHuman12070.59
LIMK1LISKTKL3s95BAstaurosporineHuman12450.59
LIMK1LISKTKL3s95AAstaurosporineHuman12460.59
LIMK1LISKTKL3s95BBstaurosporineHuman12470.59
MAPKAPK2MAPKAPKCAMK2pzyCstaurosporineHuman12790.59
MELKCAMKLCAMK5m5aABk-252aHuman87330.72
CHEK1 (CHK1)CAMKLCAMK1nvsArel-(9r,12s)-9,10,11,12-tetrahydro-9,12-epoxy-1h-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-1,3(2h)-dioneHuman15910.45
CHEK1 (CHK1)CAMKLCAMK1nvqA7-hydroxystaurosporineHuman16420.43
IRAK4IRAKTKL2nryDBstaurosporineHuman17460.59
IRAK4IRAKTKL2nryCBstaurosporineHuman17500.59
IRAK4IRAKTKL4u9aAstaurosporineHuman17510.59
IRAK4IRAKTKL4u97BstaurosporineHuman17420.59
IRAK4IRAKTKL4u97AstaurosporineHuman17540.59
IRAK4IRAKTKL2nryAAstaurosporineHuman17530.59
IRAK4IRAKTKL2nryBBstaurosporineHuman17720.59
IRAK4IRAKTKL2nryABstaurosporineHuman17770.59
IRAK4IRAKTKL2nryCAstaurosporineHuman17790.59
LYNSrcTK3a4oXstaurosporineHuman18120.59
RPS6KB1 (p70S6K)RSKAGC3a61AstaurosporineHuman18460.59
RPS6KB1 (p70S6K)RSKAGC3a60AstaurosporineHuman18520.59
RPS6KB1 (p70S6K)RSKAGC3a60BstaurosporineHuman18560.59
FYNSrcTK2dq7XstaurosporineHuman19410.59
STK16 (MPSK1)NAKOther2bujBstaurosporineHuman22300.59
STK16 (MPSK1)NAKOther2bujAstaurosporineHuman22290.59
PIM1PIMCAMK1yhsAstaurosporineHuman24440.59
ZAP70SykTK1u59ABstaurosporineHuman27330.59
ZAP70SykTK1u59AAstaurosporineHuman27340.59
RPS6KA2 (RSK1)RSKAGC2z7rAstaurosporineHuman27770.59
FESFerTK3bkbAAstaurosporineHuman28100.59
FESFerTK3cblABstaurosporineHuman28110.59
FESFerTK3bkbABstaurosporineHuman28130.59
FESFerTK3cd3AAstaurosporineHuman28140.59
FESFerTK3cd3ABstaurosporineHuman28150.59
CSKCskTK3d7tAstaurosporineHuman29410.59
METMetTK1r0pAk-252aHuman29910.72
PDPK1 (PDK1)PDK1AGC1okyAAstaurosporineHuman31640.59
PDPK1 (PDK1)PDK1AGC1okyABstaurosporineHuman31950.59
PDPK1 (PDK1)PDK1AGC1okzA7-hydroxystaurosporineHuman32090.43
MAP2K1STE7STE3eqfAk-252aHuman33170.72
DYRK1ADYRKCMGC4nctBpkc412Human37430.60
DYRK1ADYRKCMGC4nctDpkc412Human37510.60
DYRK1ADYRKCMGC4nctCpkc412Human37790.60
DYRK1ADYRKCMGC4nctApkc412Human37940.60
AAK1NAKOther4wsqBAk-252aHuman38330.72
CDK2CDKCMGC1pkdC7-hydroxystaurosporineHuman39730.43
CDK2CDKCMGC1pkdA7-hydroxystaurosporineHuman41700.43
CDK2CDKCMGC4ez7AstaurosporineHuman42400.59
CDK2CDKCMGC4erwAstaurosporineHuman43700.59
STK32A (YANK1)YANKAGC4fr4FBstaurosporineHuman46860.59
STK32A (YANK1)YANKAGC4fr4DBstaurosporineHuman46870.59
STK32A (YANK1)YANKAGC4fr4EAstaurosporineHuman46890.59
STK32A (YANK1)YANKAGC4fr4ABstaurosporineHuman46900.59
STK32A (YANK1)YANKAGC4fr4FAstaurosporineHuman46910.59
STK32A (YANK1)YANKAGC4fr4BAstaurosporineHuman46920.59
STK32A (YANK1)YANKAGC4fr4AAstaurosporineHuman46930.59
STK32A (YANK1)YANKAGC4fr4CBstaurosporineHuman46940.59
STK32A (YANK1)YANKAGC4fr4BBstaurosporineHuman46950.59
MAP3K5STE11STE2clqBBstaurosporineHuman47320.59
MAP3K5STE11STE4bf2AstaurosporineHuman47430.59
MAP3K5STE11STE4bf2BstaurosporineHuman47450.59
MAP3K5STE11STE2clqABstaurosporineHuman47360.59
MAP3K5STE11STE2clqAAstaurosporineHuman47400.59
PRKCQ (PKCt)PKCAGC1xjdAstaurosporineHuman53570.59
ALKALKTK3lcsABstaurosporineHuman53760.59
ALKALKTK3lcsAAstaurosporineHuman53810.59
STK24 (MST3)STE20STE4qmyAstaurosporineHuman55920.59
STK24 (MST3)STE20STE3ckxAstaurosporineHuman55990.59
LIMK1LISKTKL3s95ABstaurosporineHuman12480.59
RPS6KB1 (p70S6K)RSKAGC3a62AstaurosporineHuman18670.59
IRAK4IRAKTKL4u9aBstaurosporineHuman17920.59
FESFerTK3cblAAstaurosporineHuman28080.59
CSKCskTK1bygAstaurosporineHuman29430.59
STK32A (YANK1)YANKAGC4fr4CAstaurosporineHuman46840.59
STK32A (YANK1)YANKAGC4fr4DAstaurosporineHuman46880.59
TTKTTKOther3hmoAstaurosporineHuman47070.59
EPHB4 (EphB4)EphTK3zewABstaurosporineHuman3770.59
PRKAA1 (AMPKa1)CAMKLCAMK4rewAstaurosporineHuman1240.59
PRKAA2 (AMPKa2)CAMKLCAMK4cfeAstaurosporineHuman1950.59
CHEK1 (CHK1)CAMKLCAMK1nvrAstaurosporineHuman15850.59
FESFerTK3bkbACstaurosporineHuman28120.59
STK32A (YANK1)YANKAGC4fr4EBstaurosporineHuman46850.59
DAPK1DAPKCAMK1wvyAstaurosporineHuman56610.59
ERN1 (IRE1)IREOther4yzcBAstaurosporineHuman62270.59
ERN1 (IRE1)IREOther4yzcBBstaurosporineHuman62310.59
ERN1 (IRE1)IREOther4yzcABstaurosporineHuman62320.59
PRKAA2 (AMPKa2)CAMKLCAMK5ezvAAstaurosporineHuman64240.59
PRKAA2 (AMPKa2)CAMKLCAMK5ezvCBstaurosporineHuman64260.59
PRKAA2 (AMPKa2)CAMKLCAMK5ezvABstaurosporineHuman64280.59
PRKAA2 (AMPKa2)CAMKLCAMK5ezvCAstaurosporineHuman64300.59
TGFBR1 (TGFbR1)STKRTKL5e8wAAstaurosporineHuman66110.59
TGFBR1 (TGFbR1)STKRTKL5e8wABstaurosporineHuman66140.59
TGFBR2 (TGFbR2)STKRTKL5e8yAstaurosporineHuman66270.59
TGFBR1 (TGFbR1)STKRTKL5e8xABstaurosporineHuman66170.59
TGFBR1 (TGFbR1)STKRTKL5e8xAAstaurosporineHuman66150.59
ITKTecTK1sm2AstaurosporineHuman740.59
AAK1NAKOther4wsqAAk-252aHuman38340.72
AAK1NAKOther4wsqBBk-252aHuman38350.72
AAK1NAKOther4wsqABk-252aHuman38360.72
IRAK4IRAKTKL2nryBAstaurosporineHuman17580.59
IRAK4IRAKTKL2nryDAstaurosporineHuman17890.59
ERN1 (IRE1)IREOther4yzcAAstaurosporineHuman62350.59
PRKAA2 (AMPKa2)CAMKLCAMK4cffAstaurosporineHuman1910.59
MAP3K5STE11STE2clqBAstaurosporineHuman47550.59
MASTLMASTAGC5lohABstaurosporineHuman70850.59
MASTLMASTAGC5lohAAstaurosporineHuman70860.59
MASTLMASTAGC5lohBBstaurosporineHuman70870.59
MASTLMASTAGC5lohBAstaurosporineHuman70880.59
RIPK2RIPKTKL5ng2ABstaurosporineHuman80560.59
RIPK2RIPKTKL5ng2AAstaurosporineHuman80500.59
RIPK2RIPKTKL5ng2BBstaurosporineHuman80520.59
RIPK2RIPKTKL5ng2BAstaurosporineHuman80530.59
Prkaa1 (AMPKa1)CAMKLCAMK5ufuAstaurosporineMouse75900.59
RPS6KB1 (p70S6K)RSKAGC4rloBstaurosporineHuman72200.59
PRKAA2 (AMPKa2)CAMKLCAMK5isoCstaurosporineHuman79800.59
PRKAA2 (AMPKa2)CAMKLCAMK5isoAstaurosporineHuman79810.59
LCKSrcTK1qpdAstaurosporineHuman22670.59
MELKCAMKLCAMK5m5aAAk-252aHuman87350.72
EGFREGFRTK5xgnA12-(2-cyanoethyl)-6,7,12,13-tetrahydro-13-methyl-5-oxo-5h-indolo[2,3-a]pyrrolo[3,4-c]carbazoleHuman85530.46
EGFREGFRTK5xgmA12-(2-cyanoethyl)-6,7,12,13-tetrahydro-13-methyl-5-oxo-5h-indolo[2,3-a]pyrrolo[3,4-c]carbazoleHuman85520.46
PAK4STE20STE5vedAstaurosporineHuman85700.59
CHEK1 (CHK1)CAMKLCAMK5oorAstaurosporineHuman86030.59
MAPKAPK2MAPKAPKCAMK1nxkDstaurosporineHuman13340.59
MAPKAPK2MAPKAPKCAMK1nxkCstaurosporineHuman13120.59
GSK3BGSKCMGC1q3dAstaurosporineHuman7050.59
PRKAA2 (AMPKa2)CAMKLCAMK6b1uCBstaurosporineHuman98500.59
PRKAA2 (AMPKa2)CAMKLCAMK6b1uABstaurosporineHuman98490.59
PRKAA2 (AMPKa2)CAMKLCAMK6b1uAAstaurosporineHuman98480.59
PRKAA2 (AMPKa2)CAMKLCAMK6b1uCAstaurosporineHuman98470.59
PRKAA2 (AMPKa2)CAMKLCAMK6b2eAstaurosporineHuman98510.59
MAPKAPK2MAPKAPKCAMK1nxkBstaurosporineHuman12920.59
Ripk4 (ANKRD3)RIPKTKL5wnjAlestaurtinibMouse98930.69
MAPKAPK2MAPKAPKCAMK1nxkAstaurosporineHuman13420.59
Ripk4 (ANKRD3)RIPKTKL5wnlAstaurosporineMouse98910.59
PRKAA1 (AMPKa1)CAMKLCAMK6c9hAstaurosporineHuman107140.59
PRKAA1 (AMPKa1)CAMKLCAMK6c9gAstaurosporineHuman107150.59
PRKAA1 (AMPKa1)CAMKLCAMK6c9jAstaurosporineHuman107170.59
PRKAA1 (AMPKa1)CAMKLCAMK6c9fAstaurosporineHuman107160.59
CDK2CDKCMGC1aq1AstaurosporineHuman42670.59
PIK3CG (p110g)PIKAtypical1e8zAstaurosporineHuman92280.59
IRAK4IRAKTKL2oicBstaurosporineHuman17520.59
IRAK4IRAKTKL2oicAstaurosporineHuman17390.59
IRAK4IRAKTKL2oicCstaurosporineHuman17340.59
IRAK4IRAKTKL2oicDstaurosporineHuman17550.59
GSK3BGSKCMGC1q3dBstaurosporineHuman7520.59
LCKSrcTK1qpjAstaurosporineHuman22830.59