Searching for structures with analogs of Omipalisib.

Search results (8 entries covering 5 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetailsSimilarity (MFP)File
PIK3CG (p110g)PIKAtypical3l08AB2,4-difluoro-n-[2-methoxy-5-(4-pyridazin-4-ylquinolin-6-yl)pyridin-3-yl]benzenesulfonamideHuman91641.00
PIK3CG (p110g)PIKAtypical3l08AA2,4-difluoro-n-[2-methoxy-5-(4-pyridazin-4-ylquinolin-6-yl)pyridin-3-yl]benzenesulfonamideHuman92171.00
BRAFRAFTKL3skcA2,6-difluoro-n-[(5s)-3-methoxy-5h-pyrazolo[3,4-b]pyridin-5-yl]-3-[(phenylsulfonyl)amino]benzamideHuman31000.40
BRAFRAFTKL3skcB2,6-difluoro-n-[(5s)-3-methoxy-5h-pyrazolo[3,4-b]pyridin-5-yl]-3-[(phenylsulfonyl)amino]benzamideHuman31280.40
PIK3CG (p110g)PIKAtypical3s2aAn-{2-chloro-5-[4-(morpholin-4-yl)quinolin-6-yl]pyridin-3-yl}-4-fluorobenzenesulfonamideHuman91580.41
PI4KAPIKAtypical6bq1E5-{2-amino-1-[4-(morpholin-4-yl)phenyl]-1h-benzimidazol-6-yl}-n-(2-fluorophenyl)-2-methoxypyridine-3-sulfonamideHuman90690.40
PI4KAPIKAtypical6bq1A5-{2-amino-1-[4-(morpholin-4-yl)phenyl]-1h-benzimidazol-6-yl}-n-(2-fluorophenyl)-2-methoxypyridine-3-sulfonamideHuman90700.40
Pik3cd (p110d)PIKAtypical7potAn-[5-(3,6-dihydro-2h-pyran-4-yl)-2-methoxy-pyridin-3-yl]benzenesulfonamideMouse139160.40