Searching for structures with analogs of Omipalisib.
Search results (8 entries covering 5 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | Similarity (MFP) | File |
|---|---|---|---|---|---|---|---|---|---|---|---|
| PIK3CG (p110g) | PIK | Atypical | 3l08 | A | A | 2,4-difluoro-n-[2-methoxy-5-(4-pyridazin-4-ylquinolin-6-yl)pyridin-3-yl]benzenesulfonamide | Human | 9217 | 1.00 | ||
| BRAF | RAF | TKL | 3skc | A | 2,6-difluoro-n-[(5s)-3-methoxy-5h-pyrazolo[3,4-b]pyridin-5-yl]-3-[(phenylsulfonyl)amino]benzamide | Human | 3100 | 0.40 | |||
| Pik3cd (p110d) | PIK | Atypical | 7pot | A | n-[5-(3,6-dihydro-2h-pyran-4-yl)-2-methoxy-pyridin-3-yl]benzenesulfonamide | Mouse | 13916 | 0.40 | |||
| PIK3CG (p110g) | PIK | Atypical | 3l08 | A | B | 2,4-difluoro-n-[2-methoxy-5-(4-pyridazin-4-ylquinolin-6-yl)pyridin-3-yl]benzenesulfonamide | Human | 9164 | 1.00 | ||
| PIK3CG (p110g) | PIK | Atypical | 3s2a | A | n-{2-chloro-5-[4-(morpholin-4-yl)quinolin-6-yl]pyridin-3-yl}-4-fluorobenzenesulfonamide | Human | 9158 | 0.41 | |||
| PI4KA | PIK | Atypical | 6bq1 | E | 5-{2-amino-1-[4-(morpholin-4-yl)phenyl]-1h-benzimidazol-6-yl}-n-(2-fluorophenyl)-2-methoxypyridine-3-sulfonamide | Human | 9069 | 0.40 | |||
| PI4KA | PIK | Atypical | 6bq1 | A | 5-{2-amino-1-[4-(morpholin-4-yl)phenyl]-1h-benzimidazol-6-yl}-n-(2-fluorophenyl)-2-methoxypyridine-3-sulfonamide | Human | 9070 | 0.40 | |||
| BRAF | RAF | TKL | 3skc | B | 2,6-difluoro-n-[(5s)-3-methoxy-5h-pyrazolo[3,4-b]pyridin-5-yl]-3-[(phenylsulfonyl)amino]benzamide | Human | 3128 | 0.40 |
Omipalisib
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