Searching for structures with analogs of Pexidartinib.

Search results (5 entries covering 4 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetailsSimilarity (MFP)File
CSF1R (FMS)PDGFRTK4hw7A5-[(5-methoxy-1h-pyrrolo[2,3-b]pyridin-3-yl)methyl]-n-[4-(trifluoromethyl)benzyl]pyridin-2-amineHuman23040.62
CSF1R (FMS)PDGFRTK4r7hA5-[(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)methyl]-n-{[6-(trifluoromethyl)pyridin-3-yl]methyl}pyridin-2-amineHuman23081.00
KITPDGFRTK7khgAB5-[(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)methyl]-n-{[6-(trifluoromethyl)pyridin-3-yl]methyl}pyridin-2-amineHuman137881.00
KITPDGFRTK7khgAA5-[(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)methyl]-n-{[6-(trifluoromethyl)pyridin-3-yl]methyl}pyridin-2-amineHuman137861.00
KITPDGFRTK4hvsA5-(1h-pyrrolo[2,3-b]pyridin-3-ylmethyl)-n-[4-(trifluoromethyl)benzyl]pyridin-2-amineHuman4030.60