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Searching for structures with analogs of
Pexidartinib
.
Search results (5 entries covering 4 PDB structures)
#
Kinase
Family
Group
PDB
Chain
(Alternate) Model
Orthosteric ligand
Organism
Details
Similarity (MFP)
File
KIT
PDGFR
TK
7khg
A
B
5-[(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)methyl]-n-{[6-(trifluoromethyl)pyridin-3-yl]methyl}pyridin-2-amine
Human
13788
1.00
KIT
PDGFR
TK
4hvs
A
5-(1h-pyrrolo[2,3-b]pyridin-3-ylmethyl)-n-[4-(trifluoromethyl)benzyl]pyridin-2-amine
Human
403
0.60
CSF1R (FMS)
PDGFR
TK
4r7h
A
5-[(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)methyl]-n-{[6-(trifluoromethyl)pyridin-3-yl]methyl}pyridin-2-amine
Human
2308
1.00
CSF1R (FMS)
PDGFR
TK
4hw7
A
5-[(5-methoxy-1h-pyrrolo[2,3-b]pyridin-3-yl)methyl]-n-[4-(trifluoromethyl)benzyl]pyridin-2-amine
Human
2304
0.62
KIT
PDGFR
TK
7khg
A
A
5-[(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)methyl]-n-{[6-(trifluoromethyl)pyridin-3-yl]methyl}pyridin-2-amine
Human
13786
1.00
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Pexidartinib
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