| EPHA3 (EphA3) | Eph | TK | 4twn | A | B | 1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea | Human | 2865 | 0.40 | |
| EPHA3 (EphA3) | Eph | TK | 4twn | A | A | 1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea | Human | 2846 | 0.40 | |
| RIPK1 | RIPK | TKL | 4neu | B | A | 1-[4-(1-aminoisoquinolin-5-yl)phenyl]-3-(5-tert-butyl-1,2-oxazol-3-yl)urea | Human | 568 | 0.41 | |
| RIPK1 | RIPK | TKL | 4neu | A | B | 1-[4-(1-aminoisoquinolin-5-yl)phenyl]-3-(5-tert-butyl-1,2-oxazol-3-yl)urea | Human | 561 | 0.41 | |
| RIPK1 | RIPK | TKL | 4neu | B | B | 1-[4-(1-aminoisoquinolin-5-yl)phenyl]-3-(5-tert-butyl-1,2-oxazol-3-yl)urea | Human | 573 | 0.41 | |
| STK10 (LOK) | STE20 | STE | 6gtt | A | A | 1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea | Human | 10026 | 0.40 | |
| RIPK2 | RIPK | TKL | 5ar7 | A | B | 1-(5-tert-butyl-1,2-oxazol-3-yl)-3-(4-pyridin-4-yloxyphenyl)urea | Human | 6182 | 0.42 | |
| RIPK2 | RIPK | TKL | 5ar7 | B | B | 1-(5-tert-butyl-1,2-oxazol-3-yl)-3-(4-pyridin-4-yloxyphenyl)urea | Human | 6188 | 0.42 | |
| RIPK2 | RIPK | TKL | 5ar7 | A | A | 1-(5-tert-butyl-1,2-oxazol-3-yl)-3-(4-pyridin-4-yloxyphenyl)urea | Human | 6174 | 0.42 | |
| RIPK2 | RIPK | TKL | 5ar7 | B | A | 1-(5-tert-butyl-1,2-oxazol-3-yl)-3-(4-pyridin-4-yloxyphenyl)urea | Human | 6178 | 0.42 | |
| MAPK14 (p38a) | MAPK | CMGC | 3hv6 | A | | 1-[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]-3-[4-(2-morpholin-4-ylethoxy)phenyl]urea | Human | 5101 | 0.51 | |
| RIPK1 | RIPK | TKL | 4neu | A | A | 1-[4-(1-aminoisoquinolin-5-yl)phenyl]-3-(5-tert-butyl-1,2-oxazol-3-yl)urea | Human | 576 | 0.41 | |
| BRAF | RAF | TKL | 4jvg | C | | 1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea | Human | 3050 | 0.40 | |
| BRAF | RAF | TKL | 4jvg | A | | 1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea | Human | 3134 | 0.40 | |
| BRAF | RAF | TKL | 4jvg | B | | 1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea | Human | 3085 | 0.40 | |
| MAPK14 (p38a) | MAPK | CMGC | 5n66 | A | | 1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea | Human | 8524 | 0.40 | |
| MAPK14 (p38a) | MAPK | CMGC | 1kv2 | A | | 1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea | Human | 5255 | 0.40 | |
| BRAF | RAF | TKL | 4jvg | D | | 1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea | Human | 3059 | 0.40 | |
| MAPK9 (JNK2) | MAPK | CMGC | 3npc | A | | 1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea | Human | 1235 | 0.40 | |
| MAPK9 (JNK2) | MAPK | CMGC | 3npc | B | | 1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea | Human | 1237 | 0.40 | |
| PTK2B (PYK2) | FAK | TK | 3fzs | A | | 1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea | Human | 94 | 0.40 | |
| STK10 (LOK) | STE20 | STE | 6gtt | A | B | 1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea | Human | 10025 | 0.40 | |
| FLT3 | PDGFR | TK | 4rt7 | A | B | 1-(5-tert-butyl-1,2-oxazol-3-yl)-3-(4-{7-[2-(morpholin-4-yl)ethoxy]imidazo[2,1-b][1,3]benzothiazol-2-yl}phenyl)urea | Human | 627 | 1.00 | |
| FLT3 | PDGFR | TK | 4xuf | B | | 1-(5-tert-butyl-1,2-oxazol-3-yl)-3-(4-{7-[2-(morpholin-4-yl)ethoxy]imidazo[2,1-b][1,3]benzothiazol-2-yl}phenyl)urea | Human | 623 | 1.00 | |
| FLT3 | PDGFR | TK | 4rt7 | A | A | 1-(5-tert-butyl-1,2-oxazol-3-yl)-3-(4-{7-[2-(morpholin-4-yl)ethoxy]imidazo[2,1-b][1,3]benzothiazol-2-yl}phenyl)urea | Human | 626 | 1.00 | |
| FLT3 | PDGFR | TK | 4xuf | A | | 1-(5-tert-butyl-1,2-oxazol-3-yl)-3-(4-{7-[2-(morpholin-4-yl)ethoxy]imidazo[2,1-b][1,3]benzothiazol-2-yl}phenyl)urea | Human | 624 | 1.00 | |
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