| MAPK1 (Erk2) | MAPK | CMGC | 4xj0 | B | | 1-[(1s)-1-(4-chloro-3-fluorophenyl)-2-hydroxyethyl]-4-[2-(tetrahydro-2h-pyran-4-ylamino)pyrimidin-4-yl]pyridin-2(1h)-one | Human | 6049 | 0.70 | |
| CDK2 | CDK | CMGC | 5k4j | A | B | 1-[(1~{s})-1-(4-chloranyl-3-fluoranyl-phenyl)-2-oxidanyl-ethyl]-4-[2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]pyridin-2-one | Human | 6750 | 1.00 | |
| MAPK1 (Erk2) | MAPK | CMGC | 8u8j | A | | (4m)-4-{(4r)-3-[(2s)-2-methylbutyl][1,2,4]triazolo[4,3-a]pyridin-7-yl}-n-(1-methyl-1h-pyrazol-5-yl)pyrimidin-2-amine | Human | 15224 | 0.46 | |
| MAPK1 (Erk2) | MAPK | CMGC | 5bve | A | B | 2-[(1s)-1-(3-chlorophenyl)-2-hydroxyethyl]-8-[2-(tetrahydro-2h-pyran-4-ylamino)pyrimidin-4-yl]-2,3,4,5-tetrahydro-1h-pyrrolo[1,2-a][1,4]diazepin-1-one | Human | 6026 | 0.40 | |
| MAPK1 (Erk2) | MAPK | CMGC | 5k4i | A | | 1-[(1~{s})-1-(4-chloranyl-3-fluoranyl-phenyl)-2-oxidanyl-ethyl]-4-[2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]pyridin-2-one | Human | 6744 | 1.00 | |
| MAPK1 (Erk2) | MAPK | CMGC | 5bve | A | A | 2-[(1s)-1-(3-chlorophenyl)-2-hydroxyethyl]-8-[2-(tetrahydro-2h-pyran-4-ylamino)pyrimidin-4-yl]-2,3,4,5-tetrahydro-1h-pyrrolo[1,2-a][1,4]diazepin-1-one | Human | 6029 | 0.40 | |
| MAPK1 (Erk2) | MAPK | CMGC | 5bvd | A | B | 2-[(1s)-1-(3-chlorophenyl)-2-hydroxyethyl]-7-[2-(tetrahydro-2h-pyran-4-ylamino)pyrimidin-4-yl]-3,4-dihydropyrrolo[1,2-a]pyrazin-1(2h)-one | Human | 6028 | 0.40 | |
| CDK2 | CDK | CMGC | 5k4j | A | A | 1-[(1~{s})-1-(4-chloranyl-3-fluoranyl-phenyl)-2-oxidanyl-ethyl]-4-[2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]pyridin-2-one | Human | 6751 | 1.00 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6gjb | A | A | [(1~{r},4~{z})-cyclooct-4-en-1-yl] ~{n}-[4-[4-[[4-[1-[(1~{s})-1-(4-chloranyl-3-fluoranyl-phenyl)-2-oxidanyl-ethyl]-2-oxidanylidene-pyridin-4-yl]pyrimidin-2-yl]amino]pyridin-2-yl]but-3-ynyl]carbamate | Human | 10832 | 0.54 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6gjb | A | B | [(1~{r},4~{z})-cyclooct-4-en-1-yl] ~{n}-[4-[4-[[4-[1-[(1~{s})-1-(4-chloranyl-3-fluoranyl-phenyl)-2-oxidanyl-ethyl]-2-oxidanylidene-pyridin-4-yl]pyrimidin-2-yl]amino]pyridin-2-yl]but-3-ynyl]carbamate | Human | 10831 | 0.54 | |
| MAPK1 (Erk2) | MAPK | CMGC | 5nhp | A | | 5-(2-methoxyethyl)-1-methyl-2-[2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]-6,7-dihydropyrrolo[3,2-c]pyridin-4-one | Human | 7998 | 0.40 | |
| MAPK1 (Erk2) | MAPK | CMGC | 6oph | A | | 1-[(1~{s})-1-(4-chloranyl-3-fluoranyl-phenyl)-2-oxidanyl-ethyl]-4-[2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]pyridin-2-one | Human | 11509 | 1.00 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4xj0 | A | | 1-[(1s)-1-(4-chloro-3-fluorophenyl)-2-hydroxyethyl]-4-[2-(tetrahydro-2h-pyran-4-ylamino)pyrimidin-4-yl]pyridin-2(1h)-one | Human | 6048 | 0.70 | |
| MAPK1 (Erk2) | MAPK | CMGC | 5bvd | A | A | 2-[(1s)-1-(3-chlorophenyl)-2-hydroxyethyl]-7-[2-(tetrahydro-2h-pyran-4-ylamino)pyrimidin-4-yl]-3,4-dihydropyrrolo[1,2-a]pyrazin-1(2h)-one | Human | 6030 | 0.40 | |
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