Searching for structures with analogs of Roniciclib.

Search results (15 entries covering 5 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetailsSimilarity (MFP)File
CDK2CDKCMGC5ievAAroniciclibHuman65670.77
CDK2CDKCMGC5iexAA(2r,3r)-3-[(5-bromo-2-{[4-(s-cyclopropylsulfonimidoyl)phenyl]amino}pyrimidin-4-yl)oxy]butan-2-olHuman65650.75
CDK2CDKCMGC5iexAB(2r,3r)-3-[(5-bromo-2-{[4-(s-cyclopropylsulfonimidoyl)phenyl]amino}pyrimidin-4-yl)oxy]butan-2-olHuman65720.75
PTK2B (PYK2)FAKTK3h3cA4-{[4-{[(1r,2r)-2-(dimethylamino)cyclopentyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}-n-methylbenzenesulfonamideHuman960.42
CDK2CDKCMGC5ievABroniciclibHuman65700.77
MELKCAMKLCAMK5mahAA~{n}-methyl-4-[[4-[[3-[methyl(methylsulfonyl)amino]pyrazin-2-yl]methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]benzamideHuman87290.41
MELKCAMKLCAMK5mahAB~{n}-methyl-4-[[4-[[3-[methyl(methylsulfonyl)amino]pyrazin-2-yl]methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]benzamideHuman87340.41
PTK2 (FAK)FAKTK6yvyBB4-{[4-{[(1r,2r)-2-(dimethylamino)cyclopentyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}-n-methylbenzenesulfonamideHuman132670.42
PTK2 (FAK)FAKTK6yvyCB4-{[4-{[(1r,2r)-2-(dimethylamino)cyclopentyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}-n-methylbenzenesulfonamideHuman132680.42
PTK2 (FAK)FAKTK6yvyCA4-{[4-{[(1r,2r)-2-(dimethylamino)cyclopentyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}-n-methylbenzenesulfonamideHuman132690.42
PTK2 (FAK)FAKTK6yvyAB4-{[4-{[(1r,2r)-2-(dimethylamino)cyclopentyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}-n-methylbenzenesulfonamideHuman132700.42
PTK2 (FAK)FAKTK6yvyDA4-{[4-{[(1r,2r)-2-(dimethylamino)cyclopentyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}-n-methylbenzenesulfonamideHuman132730.42
PTK2 (FAK)FAKTK6yvyDB4-{[4-{[(1r,2r)-2-(dimethylamino)cyclopentyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}-n-methylbenzenesulfonamideHuman132740.42
PTK2 (FAK)FAKTK6yvyAA4-{[4-{[(1r,2r)-2-(dimethylamino)cyclopentyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}-n-methylbenzenesulfonamideHuman132750.42
PTK2 (FAK)FAKTK6yvyBA4-{[4-{[(1r,2r)-2-(dimethylamino)cyclopentyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}-n-methylbenzenesulfonamideHuman132760.42