Searching for structures with analogs of Selumetinib.

Search results (9 entries covering 8 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetailsSimilarity (MFP)File
MAP2K1STE7STE2p55A2-[(4-ethynyl-2-fluorophenyl)amino]-3,4-difluoro-n-(2-hydroxyethoxy)benzamideHuman33270.42
MAP2K1STE7STE6v2xB5-[(4-bromo-2-fluorophenyl)amino]-4-fluoro-n-(2-hydroxyethoxy)-1-methyl-1h-benzimidazole-6-carboxamideHuman131970.85
MAP2K1STE7STE6v32B5-[(4-bromo-2-chlorophenyl)amino]-4-fluoro-n-(2-hydroxyethoxy)-1-methyl-1h-benzimidazole-6-carboxamideHuman130191.00
MAP2K1STE7STE7m0tB5-[(4-bromo-2-chlorophenyl)amino]-4-fluoro-n-(2-hydroxyethoxy)-1-methyl-1h-benzimidazole-6-carboxamideHuman135121.00
MAP2K1STE7STE3eqcAB2-[(2-chloro-4-iodophenyl)amino]-n-{[(2r)-2,3-dihydroxypropyl]oxy}-3,4-difluorobenzamideHuman33000.41
MAP2K1STE7STE7m0uB5-[(4-bromo-2-fluorophenyl)amino]-4-fluoro-n-(2-hydroxyethoxy)-1-methyl-1h-benzimidazole-6-carboxamideHuman135170.85
MAP2K1STE7STE4u81A8-[(4-cyclopropyl-2-fluorophenyl)amino]-n-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-7-carboxamideHuman33010.41
MAP2K1STE7STE3eqcAA2-[(2-chloro-4-iodophenyl)amino]-n-{[(2r)-2,3-dihydroxypropyl]oxy}-3,4-difluorobenzamideHuman32800.41
MAP2K1STE7STE4u7zA5-[(4-bromo-2-chlorophenyl)amino]-4-fluoro-n-(2-hydroxyethoxy)-1-methyl-1h-benzimidazole-6-carboxamideHuman32971.00