Searching for structures with analogs of Semaxanib.

Search results (16 entries covering 8 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetailsSimilarity (MFP)File
PIM1PIMCAMK7qfmAA4-[(~{e})-(2-oxidanylidene-1~{h}-indol-3-ylidene)methyl]benzoic acidHuman145610.47
PIM1PIMCAMK7qfmAB4-[(~{e})-(2-oxidanylidene-1~{h}-indol-3-ylidene)methyl]benzoic acidHuman145600.47
CAMKK2 (CaMKK2)CAMKKOther5yvcA3-{2,4-dimethyl-5-[(z)-(2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-1h-pyrrol-3-yl}propanoic acidHuman107540.52
NEK2NEKOther2javAB5-[(z)-(5-chloro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-n-(diethylamino)ethyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman3230.43
Tbk1 (TBK1)IKKOther4jlcA3-{2,4-dimethyl-5-[(z)-(2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-1h-pyrrol-3-yl}propanoic acidMouse56980.52
DYRK1ADYRKCMGC7a53AB(3~{e})-3-[(5-methylfuran-2-yl)methylidene]-1~{h}-indol-2-oneHuman137410.53
DYRK1ADYRKCMGC7a53AA(3~{e})-3-[(5-methylfuran-2-yl)methylidene]-1~{h}-indol-2-oneHuman137550.53
FGFR1FGFRTK1fgiBA3-[(3-(2-carboxyethyl)-4-methylpyrrol-2-yl)methylene]-2-indolinoneHuman35860.49
FGFR1FGFRTK1fgiAB3-[(3-(2-carboxyethyl)-4-methylpyrrol-2-yl)methylene]-2-indolinoneHuman35520.49
FGFR1FGFRTK1fgiAA3-[(3-(2-carboxyethyl)-4-methylpyrrol-2-yl)methylene]-2-indolinoneHuman35550.49
FGFR1FGFRTK1fgiBB3-[(3-(2-carboxyethyl)-4-methylpyrrol-2-yl)methylene]-2-indolinoneHuman35800.49
RETRetTK2x2mA(3z)-3-[(3,5-dimethyl-1h-pyrrol-2-yl)methylidene]-1,3-dihydro-2h-indol-2-oneHuman33661.00
RETRetTK2x2mB(3z)-3-[(3,5-dimethyl-1h-pyrrol-2-yl)methylidene]-1,3-dihydro-2h-indol-2-oneHuman33751.00
RETRetTK2x2kAB(3z)-5-amino-3-[(3,5-dimethyl-1h-pyrrol-2-yl)methylidene]-1,3-dihydro-2h-indol-2-oneHuman33580.71
RETRetTK2x2kAA(3z)-5-amino-3-[(3,5-dimethyl-1h-pyrrol-2-yl)methylidene]-1,3-dihydro-2h-indol-2-oneHuman33600.71
NEK2NEKOther2javAA5-[(z)-(5-chloro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-n-(diethylamino)ethyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman3320.43