KLIFS - the structural kinase database

Searching for structures with analogs of Theliatinib.

Search results (19 entries covering 13 PDB structures)

Kinase	Family	Group	PDB	Chain	(Alternate) Model	Orthosteric ligand	Organism	Details	Similarity (MFP)
EGFR	EGFR	TK	4i23	A		(2e)-n-{4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}-4-(piperidin-1-yl)but-2-enamide	Human	870	0.43
AURKA (AurA)	Aur	Other	2c6e	A		n-{5-[(7-{[(2s)-2-hydroxy-3-piperidin-1-ylpropyl]oxy}-6-methoxyquinazolin-4-yl)amino]pyrimidin-2-yl}benzamide	Human	1989	0.43
EGFR	EGFR	TK	4hjo	A		[6,7-bis(2-methoxy-ethoxy)quinazoline-4-yl]-(3-ethynylphenyl)amine	Human	835	0.54
EGFR	EGFR	TK	4i24	A		(2e)-n-{4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}-4-(piperidin-1-yl)but-2-enamide	Human	831	0.43
CDK2	CDK	CMGC	1di8	A		4-[3-hydroxyanilino]-6,7-dimethoxyquinazoline	Human	4577	0.44
EGFR	EGFR	TK	9ou9	A		4-(3-chloro-2-fluoroanilino)-7-methoxyquinazolin-6-yl (2r)-2,4-dimethylpiperazine-1-carboxylate	Human	15880	0.47
EGFR	EGFR	TK	9pmz	A		icotinib	Human	15897	0.47
ILK	MLK	TKL	9d5p	A		[6,7-bis(2-methoxy-ethoxy)quinazoline-4-yl]-(3-ethynylphenyl)amine	Human	15993	0.54
AURKA (AurA)	Aur	Other	2c6e	B		n-{5-[(7-{[(2s)-2-hydroxy-3-piperidin-1-ylpropyl]oxy}-6-methoxyquinazolin-4-yl)amino]pyrimidin-2-yl}benzamide	Human	2046	0.43
MAPK14 (p38a)	MAPK	CMGC	1di9	A		4-[3-methylsulfanylanilino]-6,7-dimethoxyquinazoline	Human	5251	0.40
EGFR	EGFR	TK	1m17	A	B	[6,7-bis(2-methoxy-ethoxy)quinazoline-4-yl]-(3-ethynylphenyl)amine	Human	905	0.54
RET	Ret	TK	5amn	A		4-[3-hydroxyanilino]-6,7-dimethoxyquinazoline	Human	6412	0.44
TTBK1	TTBK	CK1	4btk	A		4-[3-hydroxyanilino]-6,7-dimethoxyquinazoline	Human	771	0.44
EGFR	EGFR	TK	4i24	B		(2e)-n-{4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}-4-(piperidin-1-yl)but-2-enamide	Human	910	0.43
EGFR	EGFR	TK	1m17	A	A	[6,7-bis(2-methoxy-ethoxy)quinazoline-4-yl]-(3-ethynylphenyl)amine	Human	873	0.54
TTBK2	TTBK	CK1	6u0k	B	A	4-[3-hydroxyanilino]-6,7-dimethoxyquinazoline	Human	12049	0.44
TTBK2	TTBK	CK1	6u0k	A	A	4-[3-hydroxyanilino]-6,7-dimethoxyquinazoline	Human	12046	0.44
TTBK2	TTBK	CK1	6u0k	B	B	4-[3-hydroxyanilino]-6,7-dimethoxyquinazoline	Human	12047	0.44
TTBK2	TTBK	CK1	6u0k	A	B	4-[3-hydroxyanilino]-6,7-dimethoxyquinazoline	Human	12048	0.44