| EGFR | EGFR | TK | 5x2f | A | A | 9-cyclohexyl-n2-[4-(4-methylpiperazin-1-yl)phenyl]-n8-phenyl-purine-2,8-diamine | Human | 9540 | 0.44 | |
| EGFR | EGFR | TK | 5x2a | A | A | n2-[4-(4-methylpiperazin-1-yl)phenyl]-n8-phenyl-9-propan-2-yl-purine-2,8-diamine | Human | 9545 | 0.40 | |
| EGFR | EGFR | TK | 5x2a | A | B | n2-[4-(4-methylpiperazin-1-yl)phenyl]-n8-phenyl-9-propan-2-yl-purine-2,8-diamine | Human | 9530 | 0.40 | |
| EGFR | EGFR | TK | 5x2f | D | A | 9-cyclohexyl-n2-[4-(4-methylpiperazin-1-yl)phenyl]-n8-phenyl-purine-2,8-diamine | Human | 9544 | 0.44 | |
| EGFR | EGFR | TK | 5x2a | C | C | n2-[4-(4-methylpiperazin-1-yl)phenyl]-n8-phenyl-9-propan-2-yl-purine-2,8-diamine | Human | 9547 | 0.40 | |
| EGFR | EGFR | TK | 5x2c | A | C | 9-cyclopentyl-n2-[4-(4-methylpiperazin-1-yl)phenyl]-n8-phenyl-purine-2,8-diamine | Human | 9566 | 0.42 | |
| EGFR | EGFR | TK | 5x2f | D | B | 9-cyclohexyl-n2-[4-(4-methylpiperazin-1-yl)phenyl]-n8-phenyl-purine-2,8-diamine | Human | 9528 | 0.44 | |
| EGFR | EGFR | TK | 5x2c | A | A | 9-cyclopentyl-n2-[4-(4-methylpiperazin-1-yl)phenyl]-n8-phenyl-purine-2,8-diamine | Human | 9572 | 0.42 | |
| MAPK1 (Erk2) | MAPK | CMGC | 5ngu | A | | 2-[2-[[4-(4-methylpiperazin-1-yl)phenyl]amino]pyrimidin-4-yl]-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one | Human | 7991 | 0.43 | |
| CDK6 | CDK | CMGC | 3nux | A | | 4-[5-chloro-3-(1-methylethyl)-1h-pyrazol-4-yl]-n-(5-piperazin-1-ylpyridin-2-yl)pyrimidin-2-amine | Human | 2807 | 0.41 | |
| CDK6 | CDK | CMGC | 5l2t | A | | 7-cyclopentyl-n,n-dimethyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}-7h-pyrrolo[2,3-d]pyrimidine-6-carboxamide | Human | 6992 | 0.51 | |
| CDK6 | CDK | CMGC | 2euf | B | | 6-acetyl-8-cyclopentyl-5-methyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 2804 | 0.46 | |
| EGFR | EGFR | TK | 5x2a | A | C | n2-[4-(4-methylpiperazin-1-yl)phenyl]-n8-phenyl-9-propan-2-yl-purine-2,8-diamine | Human | 9539 | 0.40 | |
| EGFR | EGFR | TK | 5x28 | A | | 9-cyclohexyl-n2-[4-(4-methylpiperazin-1-yl)phenyl]-n8-phenyl-purine-2,8-diamine | Human | 9538 | 0.44 | |
| EGFR | EGFR | TK | 5x2a | B | C | n2-[4-(4-methylpiperazin-1-yl)phenyl]-n8-phenyl-9-propan-2-yl-purine-2,8-diamine | Human | 9543 | 0.40 | |
| EGFR | EGFR | TK | 5x2f | B | A | 9-cyclohexyl-n2-[4-(4-methylpiperazin-1-yl)phenyl]-n8-phenyl-purine-2,8-diamine | Human | 9546 | 0.44 | |
| EGFR | EGFR | TK | 5x26 | A | | n2-[4-(4-methylpiperazin-1-yl)phenyl]-n8-phenyl-9-propan-2-yl-purine-2,8-diamine | Human | 9536 | 0.40 | |
| EGFR | EGFR | TK | 5x2a | C | A | n2-[4-(4-methylpiperazin-1-yl)phenyl]-n8-phenyl-9-propan-2-yl-purine-2,8-diamine | Human | 9537 | 0.40 | |
| EGFR | EGFR | TK | 5x2a | C | B | n2-[4-(4-methylpiperazin-1-yl)phenyl]-n8-phenyl-9-propan-2-yl-purine-2,8-diamine | Human | 9531 | 0.40 | |
| EGFR | EGFR | TK | 5x2f | A | B | 9-cyclohexyl-n2-[4-(4-methylpiperazin-1-yl)phenyl]-n8-phenyl-purine-2,8-diamine | Human | 9535 | 0.44 | |
| EGFR | EGFR | TK | 5x2a | B | A | n2-[4-(4-methylpiperazin-1-yl)phenyl]-n8-phenyl-9-propan-2-yl-purine-2,8-diamine | Human | 9526 | 0.40 | |
| EGFR | EGFR | TK | 5x2f | C | B | 9-cyclohexyl-n2-[4-(4-methylpiperazin-1-yl)phenyl]-n8-phenyl-purine-2,8-diamine | Human | 9542 | 0.44 | |
| EGFR | EGFR | TK | 5x27 | A | | 9-cyclopentyl-n2-[4-(4-methylpiperazin-1-yl)phenyl]-n8-phenyl-purine-2,8-diamine | Human | 9534 | 0.42 | |
| CDK6 | CDK | CMGC | 4tth | B | | 9-cyclopentyl-n-(5-piperazin-1-ylpyridin-2-yl)pyrido[4,5]pyrrolo[1,2-d]pyrimidin-2-amine | Human | 2803 | 0.45 | |
| CDK6 | CDK | CMGC | 5l2i | A | | 6-acetyl-8-cyclopentyl-5-methyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 6991 | 0.46 | |
| CDK6 | CDK | CMGC | 6oql | A | | 5-fluoro-n-[5-(4-methylpiperazin-1-yl)pyridin-2-yl]-4-[(4r)-4-methyl-5,6,7,8-tetrahydro-4h-pyrazolo[1,5-a]azepin-3-yl]pyrimidin-2-amine | Human | 12647 | 0.43 | |
| EGFR | EGFR | TK | 5x2c | B | A | 9-cyclopentyl-n2-[4-(4-methylpiperazin-1-yl)phenyl]-n8-phenyl-purine-2,8-diamine | Human | 9569 | 0.42 | |
| EGFR | EGFR | TK | 5x2c | B | C | 9-cyclopentyl-n2-[4-(4-methylpiperazin-1-yl)phenyl]-n8-phenyl-purine-2,8-diamine | Human | 9570 | 0.42 | |
| EGFR | EGFR | TK | 5x2c | B | B | 9-cyclopentyl-n2-[4-(4-methylpiperazin-1-yl)phenyl]-n8-phenyl-purine-2,8-diamine | Human | 9571 | 0.42 | |
| EGFR | EGFR | TK | 5x2c | A | B | 9-cyclopentyl-n2-[4-(4-methylpiperazin-1-yl)phenyl]-n8-phenyl-purine-2,8-diamine | Human | 9567 | 0.42 | |
| EGFR | EGFR | TK | 5x2f | C | A | 9-cyclohexyl-n2-[4-(4-methylpiperazin-1-yl)phenyl]-n8-phenyl-purine-2,8-diamine | Human | 9527 | 0.44 | |
| EGFR | EGFR | TK | 5x2f | B | B | 9-cyclohexyl-n2-[4-(4-methylpiperazin-1-yl)phenyl]-n8-phenyl-purine-2,8-diamine | Human | 9541 | 0.44 | |
| EGFR | EGFR | TK | 5x2a | B | B | n2-[4-(4-methylpiperazin-1-yl)phenyl]-n8-phenyl-9-propan-2-yl-purine-2,8-diamine | Human | 9548 | 0.40 | |
| CDK2 | CDK | CMGC | 6oqi | A | | 5-fluoro-n-[5-(4-methylpiperazin-1-yl)pyridin-2-yl]-4-[(4s)-4-methyl-5,6,7,8-tetrahydro-4h-pyrazolo[1,5-a]azepin-3-yl]pyrimidin-2-amine | Human | 12648 | 0.43 | |
Match: