Searching for structures with analogs of Mevociclib.

Search results (10 entries covering 7 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetailsSimilarity (MFP)File
EGFREGFRTK4li5AAn-(3-{[5-chloro-4-(1h-indol-3-yl)pyrimidin-2-yl]amino}-4-methoxyphenyl)propanamideHuman8410.44
MAPK10 (JNK3)MAPKCMGC2p33A4-{[5-chloro-4-(1h-indol-3-yl)pyrimidin-2-yl]amino}-n-ethylpiperidine-1-carboxamideHuman34550.52
MAPK10 (JNK3)MAPKCMGC4x21An-ethyl-4-{[4-(1h-indol-3-yl)-5-iodopyrimidin-2-yl]amino}piperidine-1-carboxamideHuman62400.44
EGFREGFRTK4li5ABn-(3-{[5-chloro-4-(1h-indol-3-yl)pyrimidin-2-yl]amino}-4-methoxyphenyl)propanamideHuman7970.44
CDK12 (CRK7)CDKCMGC5acbCn-[4-[(3r)-3-[[5-chloranyl-4-(1h-indol-3-yl)pyrimidin-2-yl]amino]piperidin-1-yl]carbonylphenyl]-4-(dimethylamino)butanamideHuman67010.52
CDK12 (CRK7)CDKCMGC5acbDn-[4-[(3r)-3-[[5-chloranyl-4-(1h-indol-3-yl)pyrimidin-2-yl]amino]piperidin-1-yl]carbonylphenyl]-4-(dimethylamino)butanamideHuman67020.52
CDK7CDKCMGC6xd3Jn-(3-{[5-chloro-4-(1h-indol-3-yl)pyrimidin-2-yl]amino}phenyl)-4-{[4-(dimethylamino)butanoyl]amino}benzamideHuman127720.48
MAPK10 (JNK3)MAPKCMGC4x21Bn-ethyl-4-{[4-(1h-indol-3-yl)-5-iodopyrimidin-2-yl]amino}piperidine-1-carboxamideHuman62390.44
CDK13 (CHED)CDKCMGC7nxjAn-[4-[(3r)-3-[[5-chloranyl-4-(1h-indol-3-yl)pyrimidin-2-yl]amino]piperidin-1-yl]carbonylphenyl]-4-(dimethylamino)butanamideHuman135440.52
CDK12 (CRK7)CDKCMGC7nxkA(e)-n-[4-[(1r,3r)-3-[[5-chloranyl-4-(1h-indol-3-yl)pyrimidin-2-yl]amino]cyclohexyl]oxyphenyl]-4-(dimethylamino)but-2-enamideHuman135470.67