Searching for structures with analogs of Lanraplenib.
Search results (6 entries covering 4 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | Similarity (MFP) | File |
|---|---|---|---|---|---|---|---|---|---|---|---|
| AURKA (AurA) | Aur | Other | 2xne | A | 3-chloro-n-(4-morpholin-4-ylphenyl)-6-pyridin-3-ylimidazo[1,2-a]pyrazin-8-amine | Human | 7221 | 0.42 | |||
| ACVR1 (ALK2) | STKR | TKL | 9l04 | A | 4-(1-ethyl-3-pyridin-3-yl-pyrazol-4-yl)-~{n}-[4-[4-(oxetan-3-yl)piperazin-1-yl]phenyl]pyrimidin-2-amine | Human | 15732 | 0.44 | |||
| SYK | Syk | TK | 4puz | B | 6-(1h-indazol-6-yl)-n-[4-(morpholin-4-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine | Human | 1153 | 0.49 | |||
| SYK | Syk | TK | 4puz | A | 6-(1h-indazol-6-yl)-n-[4-(morpholin-4-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine | Human | 1163 | 0.49 | |||
| SYK | Syk | TK | 6vov | B | 6-(6-aminopyrazin-2-yl)-n-{4-[4-(oxetan-3-yl)piperazin-1-yl]phenyl}imidazo[1,2-a]pyrazin-8-amine | Human | 12040 | 1.00 | |||
| SYK | Syk | TK | 6vov | A | 6-(6-aminopyrazin-2-yl)-n-{4-[4-(oxetan-3-yl)piperazin-1-yl]phenyl}imidazo[1,2-a]pyrazin-8-amine | Human | 12041 | 1.00 |
Lanraplenib
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