KLIFS - the structural kinase database

Searching for structures with analogs of Samuraciclib.

Search results (15 entries covering 8 PDB structures)

Kinase	Family	Group	PDB	Chain	(Alternate) Model	Orthosteric ligand	Organism	Details	Similarity (MFP)
CDK2	CDK	CMGC	2r3n	A	B	3-cyclopropyl-5-phenyl-n-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine	Human	4046	0.40
CDK2	CDK	CMGC	3dog	C	A	(2r)-2-{[4-(benzylamino)-8-(1-methylethyl)pyrazolo[1,5-a][1,3,5]triazin-2-yl]amino}butan-1-ol	Human	4382	0.42
CDK2	CDK	CMGC	3dog	A	A	(2r)-2-{[4-(benzylamino)-8-(1-methylethyl)pyrazolo[1,5-a][1,3,5]triazin-2-yl]amino}butan-1-ol	Human	4541	0.42
CDK7	CDK	CMGC	8p4z	A	A	2-[(3r)-piperidin-3-yl]oxy-8-propan-2-yl-n-[(2-pyrazol-1-ylphenyl)methyl]pyrazolo[1,5-a][1,3,5]triazin-4-amine	Human	14796	0.41
CDK7	CDK	CMGC	8p4z	A	B	2-[(3r)-piperidin-3-yl]oxy-8-propan-2-yl-n-[(2-pyrazol-1-ylphenyl)methyl]pyrazolo[1,5-a][1,3,5]triazin-4-amine	Human	14797	0.41
CDK2	CDK	CMGC	5jq8	A		(3s,4s)-4-[[[7-[(phenylmethyl)amino]-3-propan-2-yl-pyrazolo[1,5-a]pyrimidin-5-yl]amino]methyl]piperidin-3-ol	Human	7417	1.00
CDK7	CDK	CMGC	7b5o	J	A	(3r,4r)-4-[[[7-[(phenylmethyl)amino]-3-propan-2-yl-pyrazolo[1,5-a]pyrimidin-5-yl]amino]methyl]piperidin-3-ol	Human	13278	1.00
CDK7	CDK	CMGC	7b5q	J	A	(3r,4r)-4-[[[7-[(phenylmethyl)amino]-3-propan-2-yl-pyrazolo[1,5-a]pyrimidin-5-yl]amino]methyl]piperidin-3-ol	Human	13277	1.00
CDK2	CDK	CMGC	3dog	C	B	(2r)-2-{[4-(benzylamino)-8-(1-methylethyl)pyrazolo[1,5-a][1,3,5]triazin-2-yl]amino}butan-1-ol	Human	4121	0.42
CDK2	CDK	CMGC	3dog	A	B	(2r)-2-{[4-(benzylamino)-8-(1-methylethyl)pyrazolo[1,5-a][1,3,5]triazin-2-yl]amino}butan-1-ol	Human	4365	0.42
CDK2	CDK	CMGC	3ns9	A		(2s,3s)-3-{[7-(benzylamino)-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidin-5-yl]amino}butane-1,2,4-triol	Human	4575	0.58
CDK2	CDK	CMGC	5jq5	A		(3r,4r)-4-[[[7-[(phenylmethyl)amino]-3-propan-2-yl-pyrazolo[1,5-a]pyrimidin-5-yl]amino]methyl]piperidin-3-ol	Human	7416	1.00
CDK2	CDK	CMGC	2r3n	A	A	3-cyclopropyl-5-phenyl-n-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine	Human	4101	0.40
CDK7	CDK	CMGC	7b5o	J	B	(3r,4r)-4-[[[7-[(phenylmethyl)amino]-3-propan-2-yl-pyrazolo[1,5-a]pyrimidin-5-yl]amino]methyl]piperidin-3-ol	Human	13279	1.00
CDK7	CDK	CMGC	7b5q	J	B	(3r,4r)-4-[[[7-[(phenylmethyl)amino]-3-propan-2-yl-pyrazolo[1,5-a]pyrimidin-5-yl]amino]methyl]piperidin-3-ol	Human	13280	1.00