KLIFS - the structural kinase database

Searching for structures with analogs of Epertinib.

Kinase	Family	Group	PDB	Chain	(Alternate) Model	Orthosteric ligand	Organism	Details	Similarity (MFP)
EGFR	EGFR	TK	1xkk	A		n-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine	Human	844	0.46
ERBB4 (ErbB4)	EGFR	TK	3bbt	B		n-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine	Human	2825	0.46
ERBB4 (ErbB4)	EGFR	TK	2r4b	B	A	n-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-ethylthieno[3,2-d]pyrimidin-4-amine	Human	2818	0.46
ERBB4 (ErbB4)	EGFR	TK	3bbt	D		n-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine	Human	2819	0.46
ERBB4 (ErbB4)	EGFR	TK	2r4b	B	B	n-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-ethylthieno[3,2-d]pyrimidin-4-amine	Human	2823	0.46
ERBB4 (ErbB4)	EGFR	TK	2r4b	A	B	n-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-ethylthieno[3,2-d]pyrimidin-4-amine	Human	2827	0.46
ERBB4 (ErbB4)	EGFR	TK	2r4b	A	A	n-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-ethylthieno[3,2-d]pyrimidin-4-amine	Human	2822	0.46