Searching for structures with analogs of Pegcantratinib.

Search results (172 entries covering 86 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetailsSimilarity (MFP)File
ITKTecTK1snuBstaurosporineHuman330.55
ITKTecTK1snuAstaurosporineHuman820.55
ITKTecTK1sm2BstaurosporineHuman730.55
PRKAA1 (AMPKa1)CAMKLCAMK4rerAstaurosporineHuman1210.55
PRKAA2 (AMPKa2)CAMKLCAMK4cfeCstaurosporineHuman1920.55
IKBKB (IKKb)IKKOther4kikBBk-252aHuman2930.63
IKBKB (IKKb)IKKOther4kikAAk-252aHuman2900.63
IKBKB (IKKb)IKKOther4kikABk-252aHuman2880.63
IKBKB (IKKb)IKKOther4kikBAk-252aHuman2950.63
EPHB4 (EphB4)EphTK3zewBAstaurosporineHuman3510.55
EPHB4 (EphB4)EphTK2yn8AstaurosporineHuman3520.55
EPHB4 (EphB4)EphTK2yn8BstaurosporineHuman3490.55
EPHB4 (EphB4)EphTK3zewBBstaurosporineHuman3570.55
JAK3JakATK1yvjAB1,2,3,4-tetrahydrogen-staurosporineHuman4510.47
JAK3JakATK1yvjAA1,2,3,4-tetrahydrogen-staurosporineHuman4600.47
PKN1PKNAGC4otgAAlestaurtinibHuman5480.44
PKN1PKNAGC4otgABlestaurtinibHuman5490.44
MASTLMASTAGC5lohAAstaurosporineHuman70860.55
MASTLMASTAGC5lohABstaurosporineHuman70850.55
CDK2CDKCMGC1pkdC7-hydroxystaurosporineHuman39730.41
SYKSykTK1xbcABstaurosporineHuman12070.55
LIMK1LISKTKL3s95AAstaurosporineHuman12460.55
LIMK1LISKTKL3s95BBstaurosporineHuman12470.55
LIMK1LISKTKL3s95BAstaurosporineHuman12450.55
MAP2K6STE7STE3fmeAstaurosporineHuman12310.55
MAPKAPK2MAPKAPKCAMK2pzyCstaurosporineHuman12790.55
MELKCAMKLCAMK5m5aABk-252aHuman87330.63
IRAK4IRAKTKL4u9aAstaurosporineHuman17510.55
IRAK4IRAKTKL2nryCBstaurosporineHuman17500.55
IRAK4IRAKTKL4u97BstaurosporineHuman17420.55
IRAK4IRAKTKL2nryDBstaurosporineHuman17460.55
IRAK4IRAKTKL2nryBBstaurosporineHuman17720.55
IRAK4IRAKTKL2nryAAstaurosporineHuman17530.55
IRAK4IRAKTKL4u97AstaurosporineHuman17540.55
IRAK4IRAKTKL2nryABstaurosporineHuman17770.55
IRAK4IRAKTKL2nryCAstaurosporineHuman17790.55
RPS6KB1 (p70S6K)RSKAGC3a61AstaurosporineHuman18460.55
RPS6KB1 (p70S6K)RSKAGC3a60AstaurosporineHuman18520.55
LYNSrcTK3a4oXstaurosporineHuman18120.55
RPS6KB1 (p70S6K)RSKAGC3a60BstaurosporineHuman18560.55
STK16 (MPSK1)NAKOther2bujBstaurosporineHuman22300.55
PIM1PIMCAMK1yhsAstaurosporineHuman24440.55
FYNSrcTK2dq7XstaurosporineHuman19410.55
FESFerTK3bkbAAstaurosporineHuman28100.55
FESFerTK3cd3ABstaurosporineHuman28150.55
FESFerTK3cd3AAstaurosporineHuman28140.55
FESFerTK3cblABstaurosporineHuman28110.55
FESFerTK3bkbABstaurosporineHuman28130.55
METMetTK1r0pAk-252aHuman29910.63
PDPK1 (PDK1)PDK1AGC1okyABstaurosporineHuman31950.55
PDPK1 (PDK1)PDK1AGC1okyAAstaurosporineHuman31640.55
PDPK1 (PDK1)PDK1AGC1okzA7-hydroxystaurosporineHuman32090.41
RPS6KA1 (RSK3)RSKAGC2z7rAstaurosporineHuman27770.55
ZAP70SykTK1u59AAstaurosporineHuman27340.55
AAK1NAKOther4wsqBAk-252aHuman38330.63
DYRK1ADYRKCMGC4nctApkc412Human37940.53
DYRK1ADYRKCMGC4nctCpkc412Human37790.53
STK32A (YANK1)YANKAGC4fr4BAstaurosporineHuman46920.55
MAP3K5STE11STE4bf2AstaurosporineHuman47430.55
MAP3K5STE11STE4bf2BstaurosporineHuman47450.55
MAP3K5STE11STE2clqBBstaurosporineHuman47320.55
MAP3K5STE11STE2clqABstaurosporineHuman47360.55
MAP3K5STE11STE2clqAAstaurosporineHuman47400.55
CHEK1 (CHK1)CAMKLCAMK5oorAstaurosporineHuman86030.55
PRKCQ (PKCt)PKCAGC1xjdAstaurosporineHuman53570.55
ALKALKTK3lcsABstaurosporineHuman53760.55
STK24 (MST3)STE20STE3ckxAstaurosporineHuman55990.55
STK24 (MST3)STE20STE4qmyAstaurosporineHuman55920.55
CHEK1 (CHK1)CAMKLCAMK7akoBBstaurosporineHuman134960.55
CHEK1 (CHK1)CAMKLCAMK1nvqA7-hydroxystaurosporineHuman16420.41
RPS6KB1 (p70S6K)RSKAGC3a62AstaurosporineHuman18670.55
LIMK1LISKTKL3s95ABstaurosporineHuman12480.55
CSKCskTK1bygAstaurosporineHuman29430.55
TTKTTKOther3hmoAstaurosporineHuman47070.55
STK32A (YANK1)YANKAGC4fr4CAstaurosporineHuman46840.55
PRKAA1 (AMPKa1)CAMKLCAMK4rewAstaurosporineHuman1240.55
EPHB4 (EphB4)EphTK3zewABstaurosporineHuman3770.55
PRKAA2 (AMPKa2)CAMKLCAMK4cfeAstaurosporineHuman1950.55
CHEK1 (CHK1)CAMKLCAMK1nvrAstaurosporineHuman15850.55
FESFerTK3bkbACstaurosporineHuman28120.55
STK32A (YANK1)YANKAGC4fr4EBstaurosporineHuman46850.55
DAPK1DAPKCAMK1wvyAstaurosporineHuman56610.55
ERN1 (IRE1)IREOther4yzcABstaurosporineHuman62320.55
ERN1 (IRE1)IREOther4yzcBAstaurosporineHuman62270.55
ERN1 (IRE1)IREOther4yzcBBstaurosporineHuman62310.55
PRKAA2 (AMPKa2)CAMKLCAMK5ezvABstaurosporineHuman64280.55
PRKAA2 (AMPKa2)CAMKLCAMK5ezvCAstaurosporineHuman64300.55
PRKAA2 (AMPKa2)CAMKLCAMK5ezvCBstaurosporineHuman64260.55
PRKAA2 (AMPKa2)CAMKLCAMK5ezvAAstaurosporineHuman64240.55
TGFBR1 (TGFbR1)STKRTKL5e8wAAstaurosporineHuman66110.55
TGFBR1 (TGFbR1)STKRTKL5e8wABstaurosporineHuman66140.55
TGFBR2 (TGFbR2)STKRTKL5e8yAstaurosporineHuman66270.55
TGFBR1 (TGFbR1)STKRTKL5e8xABstaurosporineHuman66170.55
TGFBR1 (TGFbR1)STKRTKL5e8xAAstaurosporineHuman66150.55
ITKTecTK1sm2AstaurosporineHuman740.55
AAK1NAKOther4wsqAAk-252aHuman38340.63
AAK1NAKOther4wsqABk-252aHuman38360.63
AAK1NAKOther4wsqBBk-252aHuman38350.63
IRAK4IRAKTKL2nryBAstaurosporineHuman17580.55
IRAK4IRAKTKL2nryDAstaurosporineHuman17890.55
ERN1 (IRE1)IREOther4yzcAAstaurosporineHuman62350.55
PRKAA2 (AMPKa2)CAMKLCAMK4cffAstaurosporineHuman1910.55
MAP3K5STE11STE2clqBAstaurosporineHuman47550.55
MASTLMASTAGC5lohBAstaurosporineHuman70880.55
RIPK2RIPKTKL5ng2ABstaurosporineHuman80560.55
Prkaa1 (AMPKa1)CAMKLCAMK5ufuAstaurosporineMouse75900.55
RIPK2RIPKTKL5ng2BBstaurosporineHuman80520.55
RIPK2RIPKTKL5ng2AAstaurosporineHuman80500.55
RPS6KB1 (p70S6K)RSKAGC4rloBstaurosporineHuman72200.55
PRKAA2 (AMPKa2)CAMKLCAMK5isoAstaurosporineHuman79810.55
PRKAA2 (AMPKa2)CAMKLCAMK5isoCstaurosporineHuman79800.55
CDK2CDKCMGC7nvqAstaurosporineHuman136270.55
CDK2CDKCMGC1pkdA7-hydroxystaurosporineHuman41700.41
LCKSrcTK1qpdAstaurosporineHuman22670.55
SYKSykTK1xbcAAstaurosporineHuman11650.55
EGFREGFRTK5xgnA12-(2-cyanoethyl)-6,7,12,13-tetrahydro-13-methyl-5-oxo-5h-indolo[2,3-a]pyrrolo[3,4-c]carbazoleHuman85530.40
EGFREGFRTK5xgmA12-(2-cyanoethyl)-6,7,12,13-tetrahydro-13-methyl-5-oxo-5h-indolo[2,3-a]pyrrolo[3,4-c]carbazoleHuman85520.40
PAK4STE20STE5vedAstaurosporineHuman85700.55
MAPKAPK2MAPKAPKCAMK1nxkDstaurosporineHuman13340.55
DYRK1ADYRKCMGC4nctBpkc412Human37430.53
MAPKAPK2MAPKAPKCAMK1nxkCstaurosporineHuman13120.55
GSK3BGSKCMGC1q3dAstaurosporineHuman7050.55
DYRK1ADYRKCMGC4nctDpkc412Human37510.53
RIPK2RIPKTKL5ng2BAstaurosporineHuman80530.55
PRKAA2 (AMPKa2)CAMKLCAMK6b1uCBstaurosporineHuman98500.55
PRKAA2 (AMPKa2)CAMKLCAMK6b2eAstaurosporineHuman98510.55
PRKAA2 (AMPKa2)CAMKLCAMK6b1uAAstaurosporineHuman98480.55
PRKAA2 (AMPKa2)CAMKLCAMK6b1uABstaurosporineHuman98490.55
MAPKAPK2MAPKAPKCAMK1nxkBstaurosporineHuman12920.55
MAPKAPK2MAPKAPKCAMK1nxkAstaurosporineHuman13420.55
Ripk4 (ANKRD3)RIPKTKL5wnjAlestaurtinibMouse98930.44
Ripk4 (ANKRD3)RIPKTKL5wnlAstaurosporineMouse98910.55
ALKALKTK3lcsAAstaurosporineHuman53810.55
PRKAA1 (AMPKa1)CAMKLCAMK6c9fAstaurosporineHuman107160.55
PRKAA1 (AMPKa1)CAMKLCAMK6c9jAstaurosporineHuman107170.55
PRKAA1 (AMPKa1)CAMKLCAMK6c9gAstaurosporineHuman107150.55
PRKAA1 (AMPKa1)CAMKLCAMK6c9hAstaurosporineHuman107140.55
PRKAA2 (AMPKa2)CAMKLCAMK6b1uCAstaurosporineHuman98470.55
ABL1AblTK2hz4B1,2,3,4-tetrahydrogen-staurosporineHuman10580.47
CDK2CDKCMGC1aq1AstaurosporineHuman42670.55
PIK3CG (p110g)PIKAtypical1e8zAstaurosporineHuman92280.55
IRAK4IRAKTKL2oicDstaurosporineHuman17550.55
IRAK4IRAKTKL2oicAstaurosporineHuman17390.55
IRAK4IRAKTKL2oicCstaurosporineHuman17340.55
GSK3BGSKCMGC1q3dBstaurosporineHuman7520.55
LCKSrcTK1qpjAstaurosporineHuman22830.55
ZAP70SykTK1u59ABstaurosporineHuman27330.55
PRKAA2 (AMPKa2)CAMKLCAMK4cffCstaurosporineHuman1900.55
CHEK1 (CHK1)CAMKLCAMK7akoABstaurosporineHuman134950.55
CHEK1 (CHK1)CAMKLCAMK7akoAAstaurosporineHuman134900.55
CHEK1 (CHK1)CAMKLCAMK7akoBAstaurosporineHuman134920.55
FESFerTK3cblAAstaurosporineHuman28080.55
MKNK2 (MNK2)MAPKAPKCAMK2hw7AstaurosporineHuman7640.55
STK32A (YANK1)YANKAGC4fr4BBstaurosporineHuman46950.55
CDK2CDKCMGC4ez7AstaurosporineHuman42400.55
IRAK4IRAKTKL4u9aBstaurosporineHuman17920.55
STK32A (YANK1)YANKAGC4fr4FBstaurosporineHuman46860.55
CSKCskTK3d7tAstaurosporineHuman29410.55
EPHB4 (EphB4)EphTK3zewAAstaurosporineHuman3730.55
MASTLMASTAGC5lohBBstaurosporineHuman70870.55
STK32A (YANK1)YANKAGC4fr4AAstaurosporineHuman46930.55
STK32A (YANK1)YANKAGC4fr4EAstaurosporineHuman46890.55
STK32A (YANK1)YANKAGC4fr4CBstaurosporineHuman46940.55
STK32A (YANK1)YANKAGC4fr4DAstaurosporineHuman46880.55
STK32A (YANK1)YANKAGC4fr4FAstaurosporineHuman46910.55
STK32A (YANK1)YANKAGC4fr4DBstaurosporineHuman46870.55
STK32A (YANK1)YANKAGC4fr4ABstaurosporineHuman46900.55
STK16 (MPSK1)NAKOther2bujAstaurosporineHuman22290.55
IRAK4IRAKTKL2oicBstaurosporineHuman17520.55
MELKCAMKLCAMK5m5aAAk-252aHuman87350.63
MAP2K1STE7STE3eqfAk-252aHuman33170.63
CDK2CDKCMGC4erwAstaurosporineHuman43700.55