Searching for structures with analogs of Zorifertinib.

Search results (29 entries covering 21 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetailsSimilarity (MFP)File
EGFREGFRTK4i24B(2e)-n-{4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}-4-(piperidin-1-yl)but-2-enamideHuman9100.42
EPHB4 (EphB4)EphTK2vwuAn-(5-chloro-1,3-benzodioxol-4-yl)-6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin-4-amineHuman3700.44
EGFREGFRTK2ityAgefitinibHuman7900.44
EGFREGFRTK2itzAgefitinibHuman7890.44
EGFREGFRTK3ug2ABgefitinibHuman8190.44
EGFREGFRTK4i22AgefitinibHuman8230.44
EGFREGFRTK4i23A(2e)-n-{4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}-4-(piperidin-1-yl)but-2-enamideHuman8700.42
EGFREGFRTK4wkqABgefitinibHuman8370.44
EGFREGFRTK3ug2AAgefitinibHuman8980.44
RETRetTK2ivuA4-bromo-2-fluoro-n-[(4e)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4(1h)-ylidene]anilineHuman33640.46
EGFREGFRTK4wkqAAgefitinibHuman8890.44
KSR2RAFTKL5kkrB6,7-dimethoxy-~{n}-(2-methyl-4-phenoxy-phenyl)quinazolin-4-amineHuman70270.41
EGFREGFRTK4i24A(2e)-n-{4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}-4-(piperidin-1-yl)but-2-enamideHuman8310.42
EGFREGFRTK2itoAgefitinibHuman7830.44
CDK2CDKCMGC1di8A4-[3-hydroxyanilino]-6,7-dimethoxyquinazolineHuman45770.44
GAKNAKOther5y80ABgefitinibHuman103300.44
GAKNAKOther5y7zAgefitinibHuman103320.44
GAKNAKOther5y80AAgefitinibHuman103290.44
GAKNAKOther5y7zBgefitinibHuman103310.44
EGFREGFRTK5y25A(2r)-n-[4-[(3-chloranyl-4-fluoranyl-phenyl)amino]-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]-1-(2-fluoranylethanoyl)pyrrolidine-2-carboxamideHuman103730.40
TTBK2TTBKCK16u0kAA4-[3-hydroxyanilino]-6,7-dimethoxyquinazolineHuman120460.44
TTBK2TTBKCK16u0kBB4-[3-hydroxyanilino]-6,7-dimethoxyquinazolineHuman120470.44
TTBK2TTBKCK16u0kAB4-[3-hydroxyanilino]-6,7-dimethoxyquinazolineHuman120480.44
TTBK2TTBKCK16u0kBA4-[3-hydroxyanilino]-6,7-dimethoxyquinazolineHuman120490.44
MAPK14 (p38a)MAPKCMGC1di9A4-[3-methylsulfanylanilino]-6,7-dimethoxyquinazolineHuman52510.41
MAPK14 (p38a)MAPKCMGC4a9yAn-(3-{[7-methoxy-6-(2-pyrrolidin-1-ylethoxy)quinazolin-4-yl]amino}-4-methylphenyl)-2-morpholin-4-ylisonicotinamideHuman50730.40
TTBK1TTBKCK14btkA4-[3-hydroxyanilino]-6,7-dimethoxyquinazolineHuman7710.44
RETRetTK5amnA4-[3-hydroxyanilino]-6,7-dimethoxyquinazolineHuman64120.44
MAPK14 (p38a)MAPKCMGC2bakAn-(3-{[7-methoxy-6-(2-pyrrolidin-1-ylethoxy)quinazolin-4-yl]amino}-4-methylphenyl)-2-morpholin-4-ylisonicotinamideHuman51140.40