KLIFS - the structural kinase database

Searching for structures with analogs of Ritlecitinib.

Kinase	Family	Group	PDB	Chain	Orthosteric ligand	Organism	Details	Similarity (MFP)
JAK1	JakA	TK	4k77	A	4-(cyclohexylamino)pyrido[3,4-d]pyrimidin-8(7h)-one	Human	1449	0.41
JAK3	JakA	TK	5toz	A	1-{(2s,5r)-2-methyl-5-[(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}propan-1-one	Human	7163	0.75
JAK3	JakA	TK	5tts	A	1-{(3r)-3-[(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}propan-1-one	Human	7439	0.56
JAK1	JakA	TK	4k77	B	4-(cyclohexylamino)pyrido[3,4-d]pyrimidin-8(7h)-one	Human	1475	0.41