Searching for structures with analogs of Roblitinib.
Search results (12 entries covering 9 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | Similarity (MFP) | File |
|---|---|---|---|---|---|---|---|---|---|---|---|
| FGFR4 | FGFR | TK | 6jpj | A | n-[5-cyano-4-(2-methoxyethylamino)pyridin-2-yl]-7-methanoyl-6-[(4-methyl-2-oxidanylidene-piperazin-1-yl)methyl]-3,4-dihydro-2h-1,8-naphthyridine-1-carboxamide | Human | 11051 | 1.00 | |||
| FGFR4 | FGFR | TK | 7yc3 | A | 6-bromanyl-~{n}-[5-cyano-4-(2-methoxyethylamino)pyridin-2-yl]-5-methanoyl-1-(2-morpholin-4-ylethyl)pyrrolo[3,2-b]pyridine-3-carboxamide | Human | 14501 | 0.48 | |||
| FGFR4 | FGFR | TK | 6yi8 | A | B | n-[5-cyano-4-(2-methoxyethylamino)pyridin-2-yl]-7-methanoyl-6-[(4-methyl-2-oxidanylidene-piperazin-1-yl)methyl]-3,4-dihydro-2h-1,8-naphthyridine-1-carboxamide | Human | 12811 | 1.00 | ||
| FGFR4 | FGFR | TK | 6yi8 | B | A | n-[5-cyano-4-(2-methoxyethylamino)pyridin-2-yl]-7-methanoyl-6-[(4-methyl-2-oxidanylidene-piperazin-1-yl)methyl]-3,4-dihydro-2h-1,8-naphthyridine-1-carboxamide | Human | 12813 | 1.00 | ||
| FGFR4 | FGFR | TK | 6yi8 | B | B | n-[5-cyano-4-(2-methoxyethylamino)pyridin-2-yl]-7-methanoyl-6-[(4-methyl-2-oxidanylidene-piperazin-1-yl)methyl]-3,4-dihydro-2h-1,8-naphthyridine-1-carboxamide | Human | 12814 | 1.00 | ||
| FGFR4 | FGFR | TK | 7vjl | A | n-[5-(aminomethyl)-4-(2-methoxyethylamino)pyridin-2-yl]-7-[2,2,2-tris(fluoranyl)ethanoyl]-3,4-dihydro-2h-1,8-naphthyridine-1-carboxamide | Human | 14109 | 0.50 | |||
| FGFR4 | FGFR | TK | 6yi8 | A | A | n-[5-cyano-4-(2-methoxyethylamino)pyridin-2-yl]-7-methanoyl-6-[(4-methyl-2-oxidanylidene-piperazin-1-yl)methyl]-3,4-dihydro-2h-1,8-naphthyridine-1-carboxamide | Human | 12812 | 1.00 | ||
| FGFR4 | FGFR | TK | 8kh9 | A | 1-[4-[(1~{r})-1-[3,5-bis(chloranyl)pyridin-4-yl]ethoxy]-5-cyano-pyridin-2-yl]-3-[6-methanoyl-5-[(4-methyl-2-oxidanylidene-piperazin-1-yl)methyl]-3-(2-morpholin-4-ylethoxy)pyridin-2-yl]urea | Human | 15284 | 0.53 | |||
| FGFR4 | FGFR | TK | 8kh7 | A | 1-[4-[(1~{r})-1-[3,5-bis(chloranyl)pyridin-4-yl]ethoxy]-5-cyano-pyridin-2-yl]-3-[6-methanoyl-5-[(4-methyl-2-oxidanylidene-piperazin-1-yl)methyl]-3-(2-morpholin-4-ylethoxy)pyridin-2-yl]urea | Human | 15286 | 0.53 | |||
| FGFR4 | FGFR | TK | 8w5c | A | n-[5-cyano-4-(2-methoxyethylamino)pyridin-2-yl]-5-methanoyl-6-[(4-methylpiperazin-1-yl)methyl]-1-propan-2-yl-pyrrolo[3,2-b]pyridine-3-carboxamide | Human | 15288 | 0.58 | |||
| FGFR4 | FGFR | TK | 7yc1 | A | ~{n}-[5-cyano-4-(2-methoxyethylamino)pyridin-2-yl]-5-methanoyl-1-propyl-pyrrolo[3,2-b]pyridine-3-carboxamide | Human | 14498 | 0.44 | |||
| FGFR4 | FGFR | TK | 8kh8 | A | 1-[4-[(1~{r})-1-[3,5-bis(chloranyl)pyridin-4-yl]ethoxy]-5-cyano-pyridin-2-yl]-3-[6-methanoyl-5-[(4-methyl-2-oxidanylidene-piperazin-1-yl)methyl]-3-(2-morpholin-4-ylethoxy)pyridin-2-yl]urea | Human | 15285 | 0.53 |
Roblitinib
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