Searching for structures with analogs of -.
Search results (29 entries covering 10 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | Similarity (MFP) | File |
|---|---|---|---|---|---|---|---|---|---|---|---|
| CDK2 | CDK | CMGC | 4ek5 | A | B | n-(5-cyclopropyl-1h-pyrazol-3-yl)benzene-1,4-dicarboxamide | Human | 4145 | 0.40 | ||
| FGFR4 | FGFR | TK | 5nwz | A | ~{n}-[3-[2-(3,5-dimethoxyphenyl)ethyl]-1~{h}-pyrazol-5-yl]-2-(propanoylamino)benzamide | Human | 9789 | 0.42 | |||
| CDK2 | CDK | CMGC | 4ek4 | A | C | 4-bromo-n-(5-methyl-1h-pyrazol-3-yl)benzamide | Human | 4369 | 0.40 | ||
| FGFR4 | FGFR | TK | 5nwz | B | ~{n}-[3-[2-(3,5-dimethoxyphenyl)ethyl]-1~{h}-pyrazol-5-yl]-2-(propanoylamino)benzamide | Human | 9788 | 0.42 | |||
| FGFR1 | FGFR | TK | 44ad | A | A | 2-[5-[2-(3,5-dimethoxyphenyl)ethyl]-1~{h}-pyrazol-3-yl]-6-(4-methylpiperazin-1-yl)-1~{h}-benzimidazole | Human | 15682 | 0.43 | ||
| CDK2 | CDK | CMGC | 4ek5 | A | A | n-(5-cyclopropyl-1h-pyrazol-3-yl)benzene-1,4-dicarboxamide | Human | 4037 | 0.40 | ||
| FGFR1 | FGFR | TK | 4rwj | B | B | n-{3-[2-(3,5-dimethoxyphenyl)ethyl]-1h-pyrazol-5-yl}-4-[(3r,5s)-3,5-dimethylpiperazin-1-yl]benzamide | Human | 3559 | 0.74 | ||
| FGFR1 | FGFR | TK | 4v05 | A | B | n-{3-[2-(3,5-dimethoxyphenyl)ethyl]-1h-pyrazol-5-yl}-4-[(3r,5s)-3,5-dimethylpiperazin-1-yl]benzamide | Human | 3593 | 0.74 | ||
| FGFR1 | FGFR | TK | 44ad | A | B | 2-[5-[2-(3,5-dimethoxyphenyl)ethyl]-1~{h}-pyrazol-3-yl]-6-(4-methylpiperazin-1-yl)-1~{h}-benzimidazole | Human | 15672 | 0.43 | ||
| FGFR1 | FGFR | TK | 4nk9 | B | n~4~-{5-[2-(3,5-dimethoxyphenyl)ethyl]-1h-pyrazol-3-yl}-n~2~-[(3-methyl-1,2-oxazol-5-yl)methyl]pyrimidine-2,4-diamine | Human | 3535 | 0.40 | |||
| FGFR1 | FGFR | TK | 4rwk | A | B | n-{3-[2-(3,5-dimethoxyphenyl)ethyl]-1h-pyrazol-5-yl}-4-[(3r,5s)-3,5-dimethylpiperazin-1-yl]benzamide | Human | 3517 | 0.74 | ||
| FGFR1 | FGFR | TK | 4v05 | B | A | n-{3-[2-(3,5-dimethoxyphenyl)ethyl]-1h-pyrazol-5-yl}-4-[(3r,5s)-3,5-dimethylpiperazin-1-yl]benzamide | Human | 3518 | 0.74 | ||
| CDK2 | CDK | CMGC | 4ek4 | A | B | 4-bromo-n-(5-methyl-1h-pyrazol-3-yl)benzamide | Human | 3957 | 0.40 | ||
| FGFR1 | FGFR | TK | 4wun | A | B | n-{3-[2-(3,5-dimethoxyphenyl)ethyl]-1h-pyrazol-5-yl}-4-[(3r,5s)-3,5-dimethylpiperazin-1-yl]benzamide | Human | 3595 | 0.74 | ||
| FGFR1 | FGFR | TK | 4v05 | B | B | n-{3-[2-(3,5-dimethoxyphenyl)ethyl]-1h-pyrazol-5-yl}-4-[(3r,5s)-3,5-dimethylpiperazin-1-yl]benzamide | Human | 3493 | 0.74 | ||
| FGFR1 | FGFR | TK | 4rwk | A | A | n-{3-[2-(3,5-dimethoxyphenyl)ethyl]-1h-pyrazol-5-yl}-4-[(3r,5s)-3,5-dimethylpiperazin-1-yl]benzamide | Human | 3500 | 0.74 | ||
| FGFR1 | FGFR | TK | 4rwk | B | A | n-{3-[2-(3,5-dimethoxyphenyl)ethyl]-1h-pyrazol-5-yl}-4-[(3r,5s)-3,5-dimethylpiperazin-1-yl]benzamide | Human | 3591 | 0.74 | ||
| FGFR1 | FGFR | TK | 4nk9 | A | n~4~-{5-[2-(3,5-dimethoxyphenyl)ethyl]-1h-pyrazol-3-yl}-n~2~-[(3-methyl-1,2-oxazol-5-yl)methyl]pyrimidine-2,4-diamine | Human | 3550 | 0.40 | |||
| FGFR1 | FGFR | TK | 4wun | B | A | n-{3-[2-(3,5-dimethoxyphenyl)ethyl]-1h-pyrazol-5-yl}-4-[(3r,5s)-3,5-dimethylpiperazin-1-yl]benzamide | Human | 3529 | 0.74 | ||
| FGFR1 | FGFR | TK | 4rwj | A | B | n-{3-[2-(3,5-dimethoxyphenyl)ethyl]-1h-pyrazol-5-yl}-4-[(3r,5s)-3,5-dimethylpiperazin-1-yl]benzamide | Human | 3519 | 0.74 | ||
| FGFR1 | FGFR | TK | 4rwj | A | A | n-{3-[2-(3,5-dimethoxyphenyl)ethyl]-1h-pyrazol-5-yl}-4-[(3r,5s)-3,5-dimethylpiperazin-1-yl]benzamide | Human | 3584 | 0.74 | ||
| FGFR1 | FGFR | TK | 4rwk | B | B | n-{3-[2-(3,5-dimethoxyphenyl)ethyl]-1h-pyrazol-5-yl}-4-[(3r,5s)-3,5-dimethylpiperazin-1-yl]benzamide | Human | 3530 | 0.74 | ||
| FGFR1 | FGFR | TK | 4rwj | B | A | n-{3-[2-(3,5-dimethoxyphenyl)ethyl]-1h-pyrazol-5-yl}-4-[(3r,5s)-3,5-dimethylpiperazin-1-yl]benzamide | Human | 3579 | 0.74 | ||
| FGFR1 | FGFR | TK | 4v05 | A | A | n-{3-[2-(3,5-dimethoxyphenyl)ethyl]-1h-pyrazol-5-yl}-4-[(3r,5s)-3,5-dimethylpiperazin-1-yl]benzamide | Human | 3560 | 0.74 | ||
| FGFR1 | FGFR | TK | 4wun | A | A | n-{3-[2-(3,5-dimethoxyphenyl)ethyl]-1h-pyrazol-5-yl}-4-[(3r,5s)-3,5-dimethylpiperazin-1-yl]benzamide | Human | 3511 | 0.74 | ||
| FGFR1 | FGFR | TK | 4wun | B | B | n-{3-[2-(3,5-dimethoxyphenyl)ethyl]-1h-pyrazol-5-yl}-4-[(3r,5s)-3,5-dimethylpiperazin-1-yl]benzamide | Human | 3565 | 0.74 | ||
| CDK2 | CDK | CMGC | 4ek4 | A | A | 4-bromo-n-(5-methyl-1h-pyrazol-3-yl)benzamide | Human | 4212 | 0.40 | ||
| CDK2 | CDK | CMGC | 4fkg | A | A | 4-[(5-cyclopropyl-1h-pyrazol-3-yl)carbamoyl]benzoic acid | Human | 4020 | 0.41 | ||
| CDK2 | CDK | CMGC | 4fkg | A | B | 4-[(5-cyclopropyl-1h-pyrazol-3-yl)carbamoyl]benzoic acid | Human | 4559 | 0.41 |
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