Searching for structures with analogs of -.
Search results (10 entries covering 5 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | Similarity (MFP) | File |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Pik3cd (p110d) | PIK | Atypical | 7oij | A | A | 6-[[5-[2-[(1s)-1-cyclopropylethyl]-7-(methylsulfamoyl)-1-oxidanylidene-3h-isoindol-5-yl]-4-methyl-1,3-thiazol-2-yl]amino]-n-[3-(dimethylamino)propyl]pyridine-2-carboxamide | Mouse | 13801 | 0.56 | ||
| Pik3cd (p110d) | PIK | Atypical | 7oil | A | B | 2-[(1s)-1-cyclopropylethyl]-5-[4-methyl-2-[[6-(2-oxidanylidenepyrrolidin-1-yl)pyridin-2-yl]amino]-1,3-thiazol-5-yl]-7-methylsulfonyl-3h-isoindol-1-one | Mouse | 13806 | 1.00 | ||
| Pik3cd (p110d) | PIK | Atypical | 7oil | A | A | 2-[(1s)-1-cyclopropylethyl]-5-[4-methyl-2-[[6-(2-oxidanylidenepyrrolidin-1-yl)pyridin-2-yl]amino]-1,3-thiazol-5-yl]-7-methylsulfonyl-3h-isoindol-1-one | Mouse | 13804 | 1.00 | ||
| Pik3cd (p110d) | PIK | Atypical | 7ois | A | B | n-[5-[2-[(1s)-1-cyclopropylethyl]-7-[(3-methylsulfonylphenyl)sulfamoyl]-1-oxidanylidene-3h-isoindol-5-yl]-4-methyl-1,3-thiazol-2-yl]ethanamide | Mouse | 13802 | 0.58 | ||
| Pik3cd (p110d) | PIK | Atypical | 7oi4 | A | A | n-[5-[2-[(1s)-1-cyclopropylethyl]-7-[[4-[(dimethylamino)methyl]phenyl]sulfamoyl]-1-oxidanylidene-3h-isoindol-5-yl]-4-methyl-1,3-thiazol-2-yl]ethanamide | Mouse | 13800 | 0.49 | ||
| Pik3cd (p110d) | PIK | Atypical | 6ftn | A | A | ~{n}-[5-[2-[(1~{s})-1-cyclopropylethyl]-7-methyl-1-oxidanylidene-3~{h}-isoindol-5-yl]-4-methyl-1,3-thiazol-2-yl]ethanamide | Mouse | 10010 | 0.51 | ||
| Pik3cd (p110d) | PIK | Atypical | 7ois | A | A | n-[5-[2-[(1s)-1-cyclopropylethyl]-7-[(3-methylsulfonylphenyl)sulfamoyl]-1-oxidanylidene-3h-isoindol-5-yl]-4-methyl-1,3-thiazol-2-yl]ethanamide | Mouse | 13803 | 0.58 | ||
| Pik3cd (p110d) | PIK | Atypical | 6ftn | A | B | ~{n}-[5-[2-[(1~{s})-1-cyclopropylethyl]-7-methyl-1-oxidanylidene-3~{h}-isoindol-5-yl]-4-methyl-1,3-thiazol-2-yl]ethanamide | Mouse | 10011 | 0.51 | ||
| Pik3cd (p110d) | PIK | Atypical | 7oi4 | A | B | n-[5-[2-[(1s)-1-cyclopropylethyl]-7-[[4-[(dimethylamino)methyl]phenyl]sulfamoyl]-1-oxidanylidene-3h-isoindol-5-yl]-4-methyl-1,3-thiazol-2-yl]ethanamide | Mouse | 13805 | 0.49 | ||
| Pik3cd (p110d) | PIK | Atypical | 7oij | A | B | 6-[[5-[2-[(1s)-1-cyclopropylethyl]-7-(methylsulfamoyl)-1-oxidanylidene-3h-isoindol-5-yl]-4-methyl-1,3-thiazol-2-yl]amino]-n-[3-(dimethylamino)propyl]pyridine-2-carboxamide | Mouse | 13807 | 0.56 |
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