| TNNI3K (HH498) | MLK | TKL | 7mgj | A | | n-methyl-4-[4-({[3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]pyridine-2-carboxamide | Human | 13969 | 0.66 | |
| RIPK2 | RIPK | TKL | 6es0 | A | | 2-[2-fluoranyl-4-[[2-fluoranyl-4-[2-(methylcarbamoyl)pyridin-4-yl]oxy-phenyl]carbamoylamino]phenyl]sulfanylethanoic acid | Human | 9574 | 0.49 | |
| CDK2 | CDK | CMGC | 5a14 | A | B | 1-[4-(2-azanylpyrimidin-4-yl)oxyphenyl]-3-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]urea | Human | 3901 | 0.43 | |
| RIPK2 | RIPK | TKL | 6es0 | B | | 2-[2-fluoranyl-4-[[2-fluoranyl-4-[2-(methylcarbamoyl)pyridin-4-yl]oxy-phenyl]carbamoylamino]phenyl]sulfanylethanoic acid | Human | 9573 | 0.49 | |
| BRAF | RAF | TKL | 1uwj | B | | 4-{4-[({[4-chloro-3-(trifluoromethyl)phenyl]amino}carbonyl)amino]phenoxy}-n-methylpyridine-2-carboxamide | Human | 3105 | 0.91 | |
| BRAF | RAF | TKL | 1uwh | A | | 4-{4-[({[4-chloro-3-(trifluoromethyl)phenyl]amino}carbonyl)amino]phenoxy}-n-methylpyridine-2-carboxamide | Human | 3127 | 0.91 | |
| CDK8 | CDK | CMGC | 3rgf | A | A | 4-{4-[({[4-chloro-3-(trifluoromethyl)phenyl]amino}carbonyl)amino]phenoxy}-n-methylpyridine-2-carboxamide | Human | 3841 | 0.91 | |
| RIPK2 | RIPK | TKL | 5ar7 | A | B | 1-(5-tert-butyl-1,2-oxazol-3-yl)-3-(4-pyridin-4-yloxyphenyl)urea | Human | 6182 | 0.43 | |
| CDK2 | CDK | CMGC | 5a14 | A | A | 1-[4-(2-azanylpyrimidin-4-yl)oxyphenyl]-3-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]urea | Human | 3977 | 0.43 | |
| RIPK2 | RIPK | TKL | 5ar7 | B | A | 1-(5-tert-butyl-1,2-oxazol-3-yl)-3-(4-pyridin-4-yloxyphenyl)urea | Human | 6178 | 0.43 | |
| CDK8 | CDK | CMGC | 3rgf | A | B | 4-{4-[({[4-chloro-3-(trifluoromethyl)phenyl]amino}carbonyl)amino]phenoxy}-n-methylpyridine-2-carboxamide | Human | 3846 | 0.91 | |
| RIPK2 | RIPK | TKL | 5ar7 | B | B | 1-(5-tert-butyl-1,2-oxazol-3-yl)-3-(4-pyridin-4-yloxyphenyl)urea | Human | 6188 | 0.43 | |
| RIPK2 | RIPK | TKL | 5ar7 | A | A | 1-(5-tert-butyl-1,2-oxazol-3-yl)-3-(4-pyridin-4-yloxyphenyl)urea | Human | 6174 | 0.43 | |
| KDR | VEGFR | TK | 4asd | A | | 4-{4-[({[4-chloro-3-(trifluoromethyl)phenyl]amino}carbonyl)amino]phenoxy}-n-methylpyridine-2-carboxamide | Human | 5333 | 0.91 | |
| KDR | VEGFR | TK | 2qu6 | A | | 4-({2-[(4-chloro-3-{[(2s)-1-methylpyrrolidin-2-yl]methoxy}phenyl)amino]-1,3-benzoxazol-5-yl}oxy)-n-methylpyridine-2-carboxamide | Human | 5316 | 0.40 | |
| KDR | VEGFR | TK | 2oh4 | A | B | methyl (5-{4-[({[2-fluoro-5-(trifluoromethyl)phenyl]amino}carbonyl)amino]phenoxy}-1h-benzimidazol-2-yl)carbamate | Human | 5324 | 0.40 | |
| KDR | VEGFR | TK | 2oh4 | A | A | methyl (5-{4-[({[2-fluoro-5-(trifluoromethyl)phenyl]amino}carbonyl)amino]phenoxy}-1h-benzimidazol-2-yl)carbamate | Human | 5347 | 0.40 | |
| KDR | VEGFR | TK | 3wze | A | A | 4-{4-[({[4-chloro-3-(trifluoromethyl)phenyl]amino}carbonyl)amino]phenoxy}-n-methylpyridine-2-carboxamide | Human | 5336 | 0.91 | |
| KDR | VEGFR | TK | 2qu6 | B | | 4-({2-[(4-chloro-3-{[(2s)-1-methylpyrrolidin-2-yl]methoxy}phenyl)amino]-1,3-benzoxazol-5-yl}oxy)-n-methylpyridine-2-carboxamide | Human | 5340 | 0.40 | |
| KDR | VEGFR | TK | 3wze | A | B | 4-{4-[({[4-chloro-3-(trifluoromethyl)phenyl]amino}carbonyl)amino]phenoxy}-n-methylpyridine-2-carboxamide | Human | 5320 | 0.91 | |
| KDR | VEGFR | TK | 2qu5 | A | | 4-[[2-[[4-chloro-3-(trifluoromethyl)phenyl]amino]-3h-benzimidazol-5-yl]oxy]-n-methyl-pyridine-2-carboxamide | Human | 5317 | 0.60 | |
| MAPK14 (p38a) | MAPK | CMGC | 3heg | A | A | 4-{4-[({[4-chloro-3-(trifluoromethyl)phenyl]amino}carbonyl)amino]phenoxy}-n-methylpyridine-2-carboxamide | Human | 5112 | 0.91 | |
| MAPK14 (p38a) | MAPK | CMGC | 3gcs | A | A | 4-{4-[({[4-chloro-3-(trifluoromethyl)phenyl]amino}carbonyl)amino]phenoxy}-n-methylpyridine-2-carboxamide | Human | 5077 | 0.91 | |
| MAPK14 (p38a) | MAPK | CMGC | 3heg | A | B | 4-{4-[({[4-chloro-3-(trifluoromethyl)phenyl]amino}carbonyl)amino]phenoxy}-n-methylpyridine-2-carboxamide | Human | 5218 | 0.91 | |
| MAPK14 (p38a) | MAPK | CMGC | 3gcs | A | B | 4-{4-[({[4-chloro-3-(trifluoromethyl)phenyl]amino}carbonyl)amino]phenoxy}-n-methylpyridine-2-carboxamide | Human | 5052 | 0.91 | |
| MAPK13 (p38d) | MAPK | CMGC | 4eyj | A | | 1-(3-tert-butyl-1-methyl-1h-pyrazol-5-yl)-3-[4-(pyridin-4-yloxy)phenyl]urea | Human | 2949 | 0.42 | |
| BTK | Tec | TK | 5p9k | A | B | 4-[4-[[5-fluoranyl-4-[[3-(propanoylamino)phenyl]amino]pyrimidin-2-yl]amino]phenoxy]-~{n}-methyl-pyridine-2-carboxamide | Human | 7636 | 0.41 | |
| BTK | Tec | TK | 5p9k | A | C | 4-[4-[[5-fluoranyl-4-[[3-(propanoylamino)phenyl]amino]pyrimidin-2-yl]amino]phenoxy]-~{n}-methyl-pyridine-2-carboxamide | Human | 7626 | 0.41 | |
| BTK | Tec | TK | 5p9k | A | A | 4-[4-[[5-fluoranyl-4-[[3-(propanoylamino)phenyl]amino]pyrimidin-2-yl]amino]phenoxy]-~{n}-methyl-pyridine-2-carboxamide | Human | 7633 | 0.41 | |
| BRAF | RAF | TKL | 1uwh | B | | 4-{4-[({[4-chloro-3-(trifluoromethyl)phenyl]amino}carbonyl)amino]phenoxy}-n-methylpyridine-2-carboxamide | Human | 3109 | 0.91 | |
| BRAF | RAF | TKL | 1uwj | A | | 4-{4-[({[4-chloro-3-(trifluoromethyl)phenyl]amino}carbonyl)amino]phenoxy}-n-methylpyridine-2-carboxamide | Human | 3135 | 0.91 | |
| BRAF | RAF | TKL | 5hi2 | A | | 4-{4-[({[4-chloro-3-(trifluoromethyl)phenyl]amino}carbonyl)amino]phenoxy}-n-methylpyridine-2-carboxamide | Human | 6515 | 0.91 | |
| Abl1 (ABL1) | Abl | TK | 2hzn | A | | 1-[4-(pyridin-4-yloxy)phenyl]-3-[3-(trifluoromethyl)phenyl]urea | Mouse | 5701 | 0.48 | |
Match: