KLIFS - the structural kinase database

Searching for structures with analogs of -.

Kinase	Family	Group	PDB	Chain	(Alternate) Model	Orthosteric ligand	Organism	Details	Similarity (MFP)
EGFR	EGFR	TK	6tfu	B		~{n}-[3-[4-[[1-(phenylmethyl)indazol-5-yl]amino]-7~{h}-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]propanamide	Human	12842	0.41
EGFR	EGFR	TK	6tfu	A		~{n}-[3-[4-[[1-(phenylmethyl)indazol-5-yl]amino]-7~{h}-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]propanamide	Human	12844	0.41
EGFR	EGFR	TK	6tfz	A	A	~{n}-[2-(2-hydroxyethyloxy)-5-[4-[[1-(phenylmethyl)indazol-5-yl]amino]-7~{h}-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]propanamide	Human	12840	0.40
EGFR	EGFR	TK	6tfz	B	B	~{n}-[2-(2-hydroxyethyloxy)-5-[4-[[1-(phenylmethyl)indazol-5-yl]amino]-7~{h}-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]propanamide	Human	12839	0.40
EGFR	EGFR	TK	2rgp	A		n-[1-(3-fluorobenzyl)-1h-indazol-5-yl]-5-[(piperidin-1-ylamino)methyl]pyrimidine-4,6-diamine	Human	6757	0.45
EGFR	EGFR	TK	6tfz	A	B	~{n}-[2-(2-hydroxyethyloxy)-5-[4-[[1-(phenylmethyl)indazol-5-yl]amino]-7~{h}-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]propanamide	Human	12846	0.40
EGFR	EGFR	TK	3bel	A		4-amino-6-{[1-(3-fluorobenzyl)-1h-indazol-5-yl]amino}pyrimidine-5-carbaldehyde o-(2-methoxyethyl)oxime	Human	6758	0.45
EGFR	EGFR	TK	6tfz	B	A	~{n}-[2-(2-hydroxyethyloxy)-5-[4-[[1-(phenylmethyl)indazol-5-yl]amino]-7~{h}-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]propanamide	Human	12830	0.40