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Searching for structures with analogs of
Izorlisib
.
Search results (8 entries covering 6 PDB structures)
#
Kinase
Family
Group
PDB
Chain
(Alternate) Model
Orthosteric ligand
Organism
Details
Similarity (MFP)
File
PIK3CG (p110g)
PIK
Atypical
3apd
A
5-(2-morpholin-4-yl-7-pyridin-3-yl-6,7-dihydro-5h-pyrrolo[2,3-d]pyrimidin-4-yl)-pyrimidin-2-ylamine
Human
9205
0.59
PIK3CG (p110g)
PIK
Atypical
3apc
A
5-(7-methanesulfonyl-2-morpholin-4-yl-6,7-dihydro-5h-pyrrolo[2,3-d]pyrimidin-4-yl)-pyrimidin-2-ylamine
Human
9231
1.00
PIK3CG (p110g)
PIK
Atypical
3apf
A
3-[7-(1h-benzimidazol-5-yl)-2-(morpholin-4-yl)-6,7-dihydro-5h-pyrrolo[2,3-d]pyrimidin-4-yl]phenol
Human
9250
0.40
PIK3CA (p110a)
PIK
Atypical
7k6n
A
B
tert-butyl (3s)-3-[4-(2-aminopyrimidin-5-yl)-2-(morpholin-4-yl)-5,6-dihydro-7h-pyrrolo[2,3-d]pyrimidin-7-yl]-3-methylpyrrolidine-1-carboxylate
Human
13224
0.55
PIK3CA (p110a)
PIK
Atypical
7k71
A
2-(morpholin-4-yl)[4,5'-bipyrimidin]-2'-amine
Human
13219
0.45
PIK3CA (p110a)
PIK
Atypical
7k6n
A
A
tert-butyl (3s)-3-[4-(2-aminopyrimidin-5-yl)-2-(morpholin-4-yl)-5,6-dihydro-7h-pyrrolo[2,3-d]pyrimidin-7-yl]-3-methylpyrrolidine-1-carboxylate
Human
13226
0.55
PIK3CA (p110a)
PIK
Atypical
7k6o
A
B
(3s)-3-[4-(2-aminopyrimidin-5-yl)-2-(morpholin-4-yl)-5,6-dihydro-7h-pyrrolo[2,3-d]pyrimidin-7-yl]-n-methylpyrrolidine-1-sulfonamide
Human
13206
0.59
PIK3CA (p110a)
PIK
Atypical
7k6o
A
A
(3s)-3-[4-(2-aminopyrimidin-5-yl)-2-(morpholin-4-yl)-5,6-dihydro-7h-pyrrolo[2,3-d]pyrimidin-7-yl]-n-methylpyrrolidine-1-sulfonamide
Human
13207
0.59
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Izorlisib
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