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Searching for structures with analogs of
Bimiralisib
.
Search results (10 entries covering 8 PDB structures)
#
Kinase
Family
Group
PDB
Chain
(Alternate) Model
Orthosteric ligand
Organism
Details
Similarity (MFP)
File
Pik3cd (p110d)
PIK
Atypical
7r26
A
5-[2,6-di(morpholin-4-yl)pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine
Mouse
14231
0.73
PIK3CG (p110g)
PIK
Atypical
5jhb
A
[1-{4-[6-amino-4-(trifluoromethyl)pyridin-3-yl]-6-(morpholin-4-yl)-1,3,5-triazin-2-yl}-3-(chloromethyl)azetidin-3-yl]methanol
Human
9238
0.77
PIK3CA (p110a)
PIK
Atypical
7tz7
A
A
(4s,5r)-3-[2'-amino-2-(morpholin-4-yl)-4'-(trifluoromethyl)[4,5'-bipyrimidin]-6-yl]-4-(hydroxymethyl)-5-methyl-1,3-oxazolidin-2-one
Human
14223
0.40
PIK3CG (p110g)
PIK
Atypical
5jha
A
[1-{4-[6-amino-4-(trifluoromethyl)pyridin-3-yl]-6-(morpholin-4-yl)pyrimidin-2-yl}-3-(chloromethyl)azetidin-3-yl]methanol
Human
9246
0.57
Pik3cd (p110d)
PIK
Atypical
7r2b
A
(4~{s})-3-[6-[2-azanyl-4-(trifluoromethyl)pyrimidin-5-yl]-2-morpholin-4-yl-pyrimidin-4-yl]-4-methyl-1,3-oxazolidin-2-one
Mouse
14230
0.42
PIK3CA (p110a)
PIK
Atypical
7tz7
A
B
(4s,5r)-3-[2'-amino-2-(morpholin-4-yl)-4'-(trifluoromethyl)[4,5'-bipyrimidin]-6-yl]-4-(hydroxymethyl)-5-methyl-1,3-oxazolidin-2-one
Human
14222
0.40
PIK3CG (p110g)
PIK
Atypical
5oq4
A
A
5-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine
Human
9244
1.00
PIK3CA (p110a)
PIK
Atypical
6oac
A
4-(difluoromethyl)-5-{4-[(3s)-3-methylmorpholin-4-yl]-6-(morpholin-4-yl)-1,3,5-triazin-2-yl}pyridin-2-amine
Human
11381
0.56
PIK3CG (p110g)
PIK
Atypical
5oq4
A
B
5-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine
Human
9203
1.00
PIK3CG (p110g)
PIK
Atypical
3sd5
A
5-[2,6-di(morpholin-4-yl)pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine
Human
9243
0.73
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Bimiralisib
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