| IRAK4 | IRAK | TKL | 6ege | D | A | n-[2-methoxy-4-(morpholin-4-yl)phenyl]-6-(1h-pyrazol-5-yl)pyridine-2-carboxamide | Human | 10896 | 0.43 | |
| IRAK4 | IRAK | TKL | 6egd | D | A | n-[2-methoxy-4-(morpholin-4-yl)phenyl]-2-(pyridin-3-yl)-1,3-thiazole-5-carboxamide | Human | 10894 | 0.49 | |
| EGFR | EGFR | TK | 5uwd | A | | n-(3-{[2-{[4-(4-acetylpiperazin-1-yl)-2-methoxyphenyl]amino}-5-(trifluoromethyl)pyrimidin-4-yl]amino}phenyl)propanamide | Human | 8568 | 0.44 | |
| TYK2-b | JakB | TK | 6nzh | B | A | 6-[(cyclopropanecarbonyl)amino]-n-methyl-4-{[2-(methylsulfonyl)phenyl]amino}pyridine-3-carboxamide | Human | 11447 | 0.41 | |
| CHEK1 (CHK1) | CAMKL | CAMK | 5op4 | A | | [4-[[4-(ethylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino]-2-fluoranyl-5-methoxy-phenyl]-morpholin-4-yl-methanone | Human | 8613 | 0.40 | |
| EGFR | EGFR | TK | 5xdl | A | | n-[3-[[2-[[4-(4-ethanoylpiperazin-1-yl)-2-methoxy-phenyl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]phenyl]prop-2-enamide | Human | 9066 | 0.44 | |
| IRAK1 | IRAK | TKL | 6bfn | A | A | n-[2-methoxy-4-(morpholin-4-yl)phenyl]-6-(1h-pyrazol-5-yl)pyridine-2-carboxamide | Human | 8698 | 0.43 | |
| IRAK1 | IRAK | TKL | 6bfn | B | A | n-[2-methoxy-4-(morpholin-4-yl)phenyl]-6-(1h-pyrazol-5-yl)pyridine-2-carboxamide | Human | 8701 | 0.43 | |
| IRAK1 | IRAK | TKL | 6bfn | B | B | n-[2-methoxy-4-(morpholin-4-yl)phenyl]-6-(1h-pyrazol-5-yl)pyridine-2-carboxamide | Human | 8699 | 0.43 | |
| IRAK1 | IRAK | TKL | 6bfn | A | B | n-[2-methoxy-4-(morpholin-4-yl)phenyl]-6-(1h-pyrazol-5-yl)pyridine-2-carboxamide | Human | 8700 | 0.43 | |
| LCK | Src | TK | 3b2w | A | | n-[5-({[2-fluoro-3-(trifluoromethyl)phenyl]amino}carbonyl)-2-methylphenyl]-4-methoxy-2-[(4-piperazin-1-ylphenyl)amino]pyrimidine-5-carboxamide | Human | 2299 | 0.40 | |
| EGFR | EGFR | TK | 5xdk | A | | n-[3-[[2-[[4-(4-ethanoylpiperazin-1-yl)-2-methoxy-phenyl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]phenyl]prop-2-enamide | Human | 9065 | 0.44 | |
| TYK2-b | JakB | TK | 6nze | A | B | 4-[(2-carbamoylphenyl)amino]-6-[(5-fluoropyridin-2-yl)amino]-n-methylpyridine-3-carboxamide | Human | 11444 | 0.43 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4zzn | A | B | 2-[[5-chloranyl-2-(oxan-4-ylamino)pyridin-4-yl]amino]-n-methyl-benzamide | Human | 2610 | 0.47 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4zzn | A | A | 2-[[5-chloranyl-2-(oxan-4-ylamino)pyridin-4-yl]amino]-n-methyl-benzamide | Human | 2605 | 0.47 | |
| TYK2-b | JakB | TK | 6nzh | A | A | 6-[(cyclopropanecarbonyl)amino]-n-methyl-4-{[2-(methylsulfonyl)phenyl]amino}pyridine-3-carboxamide | Human | 11450 | 0.41 | |
| TYK2-b | JakB | TK | 6nzh | B | B | 6-[(cyclopropanecarbonyl)amino]-n-methyl-4-{[2-(methylsulfonyl)phenyl]amino}pyridine-3-carboxamide | Human | 11452 | 0.41 | |
| TYK2-b | JakB | TK | 6nzh | A | B | 6-[(cyclopropanecarbonyl)amino]-n-methyl-4-{[2-(methylsulfonyl)phenyl]amino}pyridine-3-carboxamide | Human | 11442 | 0.41 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 6bql | A | | 2-({5-chloro-2-[(2-methoxy-4-morpholin-4-ylphenyl)amino]pyrimidin-4-yl}amino)-n-methylbenzamide | Human | 9061 | 0.62 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 6brc | B | | 5-chloro-n~2~-{4-[4-(dimethylamino)piperidin-1-yl]-2-methoxyphenyl}-n~4~-[2-(dimethylphosphoryl)phenyl]pyrimidine-2,4-diamine | Human | 9060 | 0.40 | |
| TYK2-b | JakB | TK | 6nze | A | A | 4-[(2-carbamoylphenyl)amino]-6-[(5-fluoropyridin-2-yl)amino]-n-methylpyridine-3-carboxamide | Human | 11453 | 0.43 | |
| TYK2-b | JakB | TK | 6nze | B | A | 4-[(2-carbamoylphenyl)amino]-6-[(5-fluoropyridin-2-yl)amino]-n-methylpyridine-3-carboxamide | Human | 11448 | 0.43 | |
| IRAK4 | IRAK | TKL | 6egd | D | B | n-[2-methoxy-4-(morpholin-4-yl)phenyl]-2-(pyridin-3-yl)-1,3-thiazole-5-carboxamide | Human | 10890 | 0.49 | |
| TYK2-b | JakB | TK | 6nze | B | B | 4-[(2-carbamoylphenyl)amino]-6-[(5-fluoropyridin-2-yl)amino]-n-methylpyridine-3-carboxamide | Human | 11443 | 0.43 | |
| IRAK4 | IRAK | TKL | 6ege | A | A | n-[2-methoxy-4-(morpholin-4-yl)phenyl]-6-(1h-pyrazol-5-yl)pyridine-2-carboxamide | Human | 10897 | 0.43 | |
| IRAK4 | IRAK | TKL | 6egd | A | B | n-[2-methoxy-4-(morpholin-4-yl)phenyl]-2-(pyridin-3-yl)-1,3-thiazole-5-carboxamide | Human | 10892 | 0.49 | |
| IRAK4 | IRAK | TKL | 6ege | D | B | n-[2-methoxy-4-(morpholin-4-yl)phenyl]-6-(1h-pyrazol-5-yl)pyridine-2-carboxamide | Human | 10889 | 0.43 | |
| IRAK4 | IRAK | TKL | 6egd | A | A | n-[2-methoxy-4-(morpholin-4-yl)phenyl]-2-(pyridin-3-yl)-1,3-thiazole-5-carboxamide | Human | 10895 | 0.49 | |
| IRAK4 | IRAK | TKL | 6ege | A | B | n-[2-methoxy-4-(morpholin-4-yl)phenyl]-6-(1h-pyrazol-5-yl)pyridine-2-carboxamide | Human | 10891 | 0.43 | |
| TTK | TTK | Other | 3gfw | A | | 1-(4-(4-(2-(isopropylsulfonyl)phenylamino)-1h-pyrrolo[2,3-b]pyridin-6-ylamino)-3-methoxyphenyl)piperidin-4-ol | Human | 4714 | 0.47 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 6brc | A | | 5-chloro-n~2~-{4-[4-(dimethylamino)piperidin-1-yl]-2-methoxyphenyl}-n~4~-[2-(dimethylphosphoryl)phenyl]pyrimidine-2,4-diamine | Human | 9062 | 0.40 | |
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