Searching for structures with analogs of -.

Search results (17 entries covering 9 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetailsSimilarity (MFP)File
FGFR4FGFRTK6v9cAAn-[(3r,4s)-4-{[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl]amino}oxolan-3-yl]prop-2-enamideHuman120960.56
STK24 (MST3)STE20STE8bzjAB8-(4-azanylbutyl)-6-[2-chloranyl-4-(6-methylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-oneHuman145830.42
STK24 (MST3)STE20STE8bzjAA8-(4-azanylbutyl)-6-[2-chloranyl-4-(6-methylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-oneHuman145860.42
STK24 (MST3)STE20STE8bziAB8-(4-azanylbutyl)-6-[2,5-bis(fluoranyl)-4-(6-methylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-oneHuman145840.40
FGFR4FGFRTK4xcuABn-(2-{[6-(2,6-dichloro-3,5-dimethoxyphenyl)quinazolin-2-yl]amino}-3-methylphenyl)prop-2-enamideHuman9240.41
FGFR4FGFRTK6v9cABn-[(3r,4s)-4-{[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl]amino}oxolan-3-yl]prop-2-enamideHuman120950.56
STK24 (MST3)STE20STE7b35B8-[(5-azanyl-1,3-dioxan-2-yl)methyl]-6-[2-chloranyl-4-(3-methoxy-6-methyl-pyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-oneHuman130460.41
STK24 (MST3)STE20STE8bziAA8-(4-azanylbutyl)-6-[2,5-bis(fluoranyl)-4-(6-methylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-oneHuman145850.40
FGFR4FGFRTK7f3mA6-[2,6-bis(chloranyl)-3,5-dimethoxy-phenyl]-2-(methylamino)-8-[3-(4-prop-2-enoylpiperazin-1-yl)propyl]pyrido[2,3-d]pyrimidin-7-oneHuman140341.00
STK24 (MST3)STE20STE7b35A8-[(5-azanyl-1,3-dioxan-2-yl)methyl]-6-[2-chloranyl-4-(3-methoxy-6-methyl-pyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-oneHuman130520.41
FGFR4FGFRTK4xcuAAn-(2-{[6-(2,6-dichloro-3,5-dimethoxyphenyl)quinazolin-2-yl]amino}-3-methylphenyl)prop-2-enamideHuman9280.41
EPHA2 (EphA2)EphTK8binAC8-(4-azanylbutyl)-6-(2-chlorophenyl)-2-(methylamino)pyrido[2,3-d]pyrimidin-7-oneHuman145120.48
EPHA2 (EphA2)EphTK8bioAB8-(4-azanylbutyl)-6-[2-chloranyl-5-(trifluoromethyl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-oneHuman145130.46
EPHA2 (EphA2)EphTK8binAB8-(4-azanylbutyl)-6-(2-chlorophenyl)-2-(methylamino)pyrido[2,3-d]pyrimidin-7-oneHuman145150.48
EPHA2 (EphA2)EphTK8binAA8-(4-azanylbutyl)-6-(2-chlorophenyl)-2-(methylamino)pyrido[2,3-d]pyrimidin-7-oneHuman145140.48
PAK1STE20STE5imeA8-(3-aminopropyl)-6-[2-chloro-4-(3-methyl-2-oxopyrazin-1(2h)-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8h)-oneHuman66440.41
PAK1STE20STE5imeB8-(3-aminopropyl)-6-[2-chloro-4-(3-methyl-2-oxopyrazin-1(2h)-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8h)-oneHuman66430.41