Searching for structures with analogs of -.
Search results (23 entries covering 14 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | Similarity (MFP) | File |
|---|---|---|---|---|---|---|---|---|---|---|---|
| CDK2 | CDK | CMGC | 2vu3 | A | B | 4-{[(2,6-dichlorophenyl)carbonyl]amino}-n-piperidin-4-yl-1h-pyrazole-3-carboxamide | Human | 3884 | 1.00 | ||
| CDK1 (CDC2) | CDK | CMGC | 5hq0 | A | B | {[(2,6-difluorophenyl)carbonyl]amino}-n-(4-fluorophenyl)-1h-pyrazole-3-carboxamide | Human | 6421 | 0.46 | ||
| CDK2 | CDK | CMGC | 2vtt | A | 4-{[(2,6-difluorophenyl)carbonyl]amino}-n-[(3s)-piperidin-3-yl]-1h-pyrazole-3-carboxamide | Human | 4100 | 0.61 | |||
| CDK2 | CDK | CMGC | 2vu3 | A | A | 4-{[(2,6-dichlorophenyl)carbonyl]amino}-n-piperidin-4-yl-1h-pyrazole-3-carboxamide | Human | 4582 | 1.00 | ||
| CDK1 (CDC2) | CDK | CMGC | 4y72 | A | A | {[(2,6-difluorophenyl)carbonyl]amino}-n-(4-fluorophenyl)-1h-pyrazole-3-carboxamide | Human | 4610 | 0.46 | ||
| EPHA2 (EphA2) | Eph | TK | 8bk0 | A | B | ~{n}-(2-chlorophenyl)-6-piperidin-4-yl-imidazo[1,2-a]pyridine-3-carboxamide | Human | 14503 | 0.42 | ||
| EPHA2 (EphA2) | Eph | TK | 8bk0 | A | A | ~{n}-(2-chlorophenyl)-6-piperidin-4-yl-imidazo[1,2-a]pyridine-3-carboxamide | Human | 14504 | 0.42 | ||
| JAK2 | JakA | TK | 4gfm | A | A | 2,6-dichloro-n-(2-oxo-2,5-dihydropyridin-4-yl)benzamide | Human | 3680 | 0.42 | ||
| CDK1 (CDC2) | CDK | CMGC | 4y72 | A | B | {[(2,6-difluorophenyl)carbonyl]amino}-n-(4-fluorophenyl)-1h-pyrazole-3-carboxamide | Human | 4609 | 0.46 | ||
| CDK2 | CDK | CMGC | 2vtq | A | {[(2,6-difluorophenyl)carbonyl]amino}-n-piperidin-4-yl-1h-pyrazole-3-carboxamide | Human | 3891 | 0.76 | |||
| CDK2 | CDK | CMGC | 2vtp | A | A | {[(2,6-difluorophenyl)carbonyl]amino}-n-(4-fluorophenyl)-1h-pyrazole-3-carboxamide | Human | 4511 | 0.46 | ||
| CDK2 | CDK | CMGC | 2vtp | A | B | {[(2,6-difluorophenyl)carbonyl]amino}-n-(4-fluorophenyl)-1h-pyrazole-3-carboxamide | Human | 4401 | 0.46 | ||
| CDK2 | CDK | CMGC | 9jj5 | A | ~{n}-(4-azanylcyclohexyl)-4-[[2,6-bis(fluoranyl)-3-[4-(methylcarbamoyl)phenyl]phenyl]carbonylamino]-1~{h}-pyrazole-3-carboxamide | Human | 15942 | 0.49 | |||
| EPHA2 (EphA2) | Eph | TK | 5njz | A | A | ~{n}-(2-chloranyl-6-methyl-phenyl)-2-[[3-(piperidin-4-ylcarbamoyl)phenyl]amino]-1,3-thiazole-5-carboxamide | Human | 8093 | 0.40 | ||
| EPHA2 (EphA2) | Eph | TK | 5njz | A | B | ~{n}-(2-chloranyl-6-methyl-phenyl)-2-[[3-(piperidin-4-ylcarbamoyl)phenyl]amino]-1,3-thiazole-5-carboxamide | Human | 8085 | 0.40 | ||
| CDKL5 | CDKL | CMGC | 8cie | A | 4-[[3,5-bis(fluoranyl)phenyl]carbonylamino]-~{n}-piperidin-4-yl-1~{h}-pyrazole-3-carboxamide | Human | 14778 | 0.61 | |||
| CDK1 (CDC2) | CDK | CMGC | 5hq0 | A | A | {[(2,6-difluorophenyl)carbonyl]amino}-n-(4-fluorophenyl)-1h-pyrazole-3-carboxamide | Human | 6422 | 0.46 | ||
| JAK2 | JakA | TK | 4gfm | A | B | 2,6-dichloro-n-(2-oxo-2,5-dihydropyridin-4-yl)benzamide | Human | 3705 | 0.42 | ||
| CDC42BPB (MRCKb) | DMPK | AGC | 4ual | A | A | 4-chloro-1-(piperidin-4-yl)-n-[3-(pyridin-2-yl)-1h-pyrazol-4-yl]-1h-pyrazole-3-carboxamide | Human | 4861 | 0.44 | ||
| CDC42BPB (MRCKb) | DMPK | AGC | 4ual | A | B | 4-chloro-1-(piperidin-4-yl)-n-[3-(pyridin-2-yl)-1h-pyrazol-4-yl]-1h-pyrazole-3-carboxamide | Human | 4858 | 0.44 | ||
| TYK2 | JakA | TK | 4gfo | A | A | 2,6-dichloro-n-(2-oxo-2,5-dihydropyridin-4-yl)benzamide | Human | 3336 | 0.42 | ||
| TYK2 | JakA | TK | 4gfo | A | B | 2,6-dichloro-n-(2-oxo-2,5-dihydropyridin-4-yl)benzamide | Human | 3338 | 0.42 | ||
| CDK2 | CDK | CMGC | 8ypw | A | methyl 3-[4-[3-[[3-[(1-ethylsulfonylpiperidin-4-yl)carbamoyl]-1~{h}-pyrazol-4-yl]carbamoyl]-2,4-bis(fluoranyl)phenyl]piperidin-1-yl]-3-oxidanylidene-propanoate | Human | 15928 | 0.42 |
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