KLIFS - the structural kinase database

Searching for structures with analogs of -.

Search results (12 entries covering 6 PDB structures)

Kinase	Family	Group	PDB	Chain	(Alternate) Model	Orthosteric ligand	Organism	Details	Similarity (MFP)
EGFR	EGFR	TK	2itp	A	A	6-{4-[(4-ethylpiperazin-1-yl)methyl]phenyl}-n-[(1r)-1-phenylethyl]-7h-pyrrolo[2,3-d]pyrimidin-4-amine	Human	880	1.00
EGFR	EGFR	TK	2jiu	A		6-{4-[(4-ethylpiperazin-1-yl)methyl]phenyl}-n-[(1r)-1-phenylethyl]-7h-pyrrolo[2,3-d]pyrimidin-4-amine	Human	858	1.00
EGFR	EGFR	TK	2itt	A	B	6-{4-[(4-ethylpiperazin-1-yl)methyl]phenyl}-n-[(1r)-1-phenylethyl]-7h-pyrrolo[2,3-d]pyrimidin-4-amine	Human	891	1.00
PIK3CG (p110g)	PIK	Atypical	8sc8	A	A	n-[(5p)-2-chloro-5-(4-{[(1r)-1-phenylethyl]amino}quinazolin-6-yl)pyridin-3-yl]methanesulfonamide	Human	15289	0.40
PIK3CG (p110g)	PIK	Atypical	8sc8	A	C	n-[(5p)-2-chloro-5-(4-{[(1r)-1-phenylethyl]amino}quinazolin-6-yl)pyridin-3-yl]methanesulfonamide	Human	15290	0.40
PIK3CG (p110g)	PIK	Atypical	8sc8	A	B	n-[(5p)-2-chloro-5-(4-{[(1r)-1-phenylethyl]amino}quinazolin-6-yl)pyridin-3-yl]methanesulfonamide	Human	15291	0.40
EGFR	EGFR	TK	8sc7	A	B	n-[(5p)-2-chloro-5-(4-{[(1r)-1-phenylethyl]amino}quinazolin-6-yl)pyridin-3-yl]methanesulfonamide	Human	15324	0.40
EGFR	EGFR	TK	8sc7	A	A	n-[(5p)-2-chloro-5-(4-{[(1r)-1-phenylethyl]amino}quinazolin-6-yl)pyridin-3-yl]methanesulfonamide	Human	15325	0.40
EGFR	EGFR	TK	8sc7	A	C	n-[(5p)-2-chloro-5-(4-{[(1r)-1-phenylethyl]amino}quinazolin-6-yl)pyridin-3-yl]methanesulfonamide	Human	15326	0.40
EGFR	EGFR	TK	2itt	A	A	6-{4-[(4-ethylpiperazin-1-yl)methyl]phenyl}-n-[(1r)-1-phenylethyl]-7h-pyrrolo[2,3-d]pyrimidin-4-amine	Human	892	1.00
EGFR	EGFR	TK	2itp	A	B	6-{4-[(4-ethylpiperazin-1-yl)methyl]phenyl}-n-[(1r)-1-phenylethyl]-7h-pyrrolo[2,3-d]pyrimidin-4-amine	Human	871	1.00
EGFR	EGFR	TK	2j6m	A		6-{4-[(4-ethylpiperazin-1-yl)methyl]phenyl}-n-[(1r)-1-phenylethyl]-7h-pyrrolo[2,3-d]pyrimidin-4-amine	Human	900	1.00