Searching for structures with analogs of -.

Search results (24 entries covering 17 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetailsSimilarity (MFP)File
EGFREGFRTK4i23A(2e)-n-{4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}-4-(piperidin-1-yl)but-2-enamideHuman8700.53
EGFREGFRTK4g5jABn-{4-[(3-chloro-4-fluorophenyl)amino]-7-[(3s)-tetrahydrofuran-3-yloxy]quinazolin-6-yl}-4-(dimethylamino)butanamideHuman8520.42
EGFREGFRTK3ug2AAgefitinibHuman8980.43
GAKNAKOther5y80AAgefitinibHuman103290.43
GAKNAKOther5y7zAgefitinibHuman103320.43
EGFREGFRTK4i24A(2e)-n-{4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}-4-(piperidin-1-yl)but-2-enamideHuman8310.53
GAKNAKOther5y7zBgefitinibHuman103310.43
EGFREGFRTK2j5fAn-[4-(3-bromo-phenylamino)-quinazolin-6-yl]-acrylamideHuman8620.42
EGFREGFRTK8hy7A~{n}-[3-[[6-fluoranyl-2-[[4-(4-methylpiperazin-1-yl)phenyl]amino]quinazolin-4-yl]amino]phenyl]prop-2-enamideHuman149410.40
EGFREGFRTK3ug2ABgefitinibHuman8190.43
EGFREGFRTK2itoAgefitinibHuman7830.43
EGFREGFRTK2itzAgefitinibHuman7890.43
PKMYT1 (MYT1)WEEOther5vcwB(2e)-n-{4-[(3-chloro-4-fluorophenyl)amino]-3-cyano-7-ethoxyquinolin-6-yl}-4-(dimethylamino)but-2-enamideHuman83460.40
PKMYT1 (MYT1)WEEOther5vcwA(2e)-n-{4-[(3-chloro-4-fluorophenyl)amino]-3-cyano-7-ethoxyquinolin-6-yl}-4-(dimethylamino)but-2-enamideHuman83350.40
EGFREGFRTK5y25A(2r)-n-[4-[(3-chloranyl-4-fluoranyl-phenyl)amino]-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]-1-(2-fluoranylethanoyl)pyrrolidine-2-carboxamideHuman103730.42
EGFREGFRTK4g5jAAn-{4-[(3-chloro-4-fluorophenyl)amino]-7-[(3s)-tetrahydrofuran-3-yloxy]quinazolin-6-yl}-4-(dimethylamino)butanamideHuman7940.42
EGFREGFRTK4lqmAn-[4-(3-bromo-phenylamino)-quinazolin-6-yl]-acrylamideHuman7850.42
GAKNAKOther5y80ABgefitinibHuman103300.43
EGFREGFRTK4i22AgefitinibHuman8230.43
EGFREGFRTK4wkqAAgefitinibHuman8890.43
EGFREGFRTK4g5pAn-{4-[(3-chloro-4-fluorophenyl)amino]-7-[(3s)-tetrahydrofuran-3-yloxy]quinazolin-6-yl}-4-(dimethylamino)butanamideHuman8090.42
EGFREGFRTK4wkqABgefitinibHuman8370.43
EGFREGFRTK4i24B(2e)-n-{4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}-4-(piperidin-1-yl)but-2-enamideHuman9100.53
EGFREGFRTK2ityAgefitinibHuman7900.43