Searching for structures with analogs of Taletrectinib.

Search results (13 entries covering 7 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetailsSimilarity (MFP)File
DAPK3DAPKCAMK3bqrAA4-(6-{[(1r)-1-(hydroxymethyl)propyl]amino}imidazo[1,2-b]pyridazin-3-yl)benzoic acidHuman3800.40
DAPK3DAPKCAMK3bqrAB4-(6-{[(1r)-1-(hydroxymethyl)propyl]amino}imidazo[1,2-b]pyridazin-3-yl)benzoic acidHuman3860.40
PIM1PIMCAMK2c3iBA1-(3-{6-[(cyclopropylmethyl)amino]imidazo[1,2-b]pyridazin-3-yl}phenyl)ethanoneHuman23480.40
PIM1PIMCAMK2c3iBB1-(3-{6-[(cyclopropylmethyl)amino]imidazo[1,2-b]pyridazin-3-yl}phenyl)ethanoneHuman23740.40
HASPIN (Haspin)HaspinOther3f2nAA(2s)-2-{[3-(3-aminophenyl)imidazo[1,2-b]pyridazin-6-yl]amino}-3-methylbutan-1-olHuman38030.48
HASPIN (Haspin)HaspinOther3f2nAB(2s)-2-{[3-(3-aminophenyl)imidazo[1,2-b]pyridazin-6-yl]amino}-3-methylbutan-1-olHuman38130.48
ERN1 (IRE1)IREOther4z7hA2-methoxy-4-[6-(propan-2-ylamino)imidazo[1,2-b]pyridazin-3-yl]benzamideHuman17940.45
ERN1 (IRE1)IREOther4z7hB2-methoxy-4-[6-(propan-2-ylamino)imidazo[1,2-b]pyridazin-3-yl]benzamideHuman18010.45
ALKALKTK6edlABn-[(1s)-1-(2,4-difluorophenyl)ethyl]-3-(5-methyl-1h-pyrazol-3-yl)imidazo[1,2-b]pyridazin-6-amineHuman112650.43
ALKALKTK6edlAAn-[(1s)-1-(2,4-difluorophenyl)ethyl]-3-(5-methyl-1h-pyrazol-3-yl)imidazo[1,2-b]pyridazin-6-amineHuman112670.43
CLK1CLKCMGC6ytaAA1-(3-{6-[(cyclopropylmethyl)amino]imidazo[1,2-b]pyridazin-3-yl}phenyl)ethanoneHuman124230.40
CLK1CLKCMGC6ytaAB1-(3-{6-[(cyclopropylmethyl)amino]imidazo[1,2-b]pyridazin-3-yl}phenyl)ethanoneHuman124170.40
ACVR1 (ALK2)STKRTKL4dymA1-(3-{6-[(cyclopropylmethyl)amino]imidazo[1,2-b]pyridazin-3-yl}phenyl)ethanoneHuman15090.40