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Searching for structures with analogs of
-
.
Search results (7 entries covering 5 PDB structures)
#
Kinase
Family
Group
PDB
Chain
(Alternate) Model
Orthosteric ligand
Organism
Details
Similarity (MFP)
File
EGFR
EGFR
TK
5uwd
A
n-(3-{[2-{[4-(4-acetylpiperazin-1-yl)-2-methoxyphenyl]amino}-5-(trifluoromethyl)pyrimidin-4-yl]amino}phenyl)propanamide
Human
8568
0.40
FGFR4
FGFR
TK
4xcu
A
B
n-(2-{[6-(2,6-dichloro-3,5-dimethoxyphenyl)quinazolin-2-yl]amino}-3-methylphenyl)prop-2-enamide
Human
924
0.41
EGFR
EGFR
TK
5xdk
A
n-[3-[[2-[[4-(4-ethanoylpiperazin-1-yl)-2-methoxy-phenyl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]phenyl]prop-2-enamide
Human
9065
0.52
FGFR4
FGFR
TK
4xcu
A
A
n-(2-{[6-(2,6-dichloro-3,5-dimethoxyphenyl)quinazolin-2-yl]amino}-3-methylphenyl)prop-2-enamide
Human
928
0.41
MAPK1 (Erk2)
MAPK
CMGC
5lck
A
B
~{n}-[2-[[2-[(5-methoxypyridin-3-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]phenyl]propanamide
Human
6836
0.47
MAPK1 (Erk2)
MAPK
CMGC
5lck
A
A
~{n}-[2-[[2-[(5-methoxypyridin-3-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]phenyl]propanamide
Human
6835
0.47
EGFR
EGFR
TK
5xdl
A
n-[3-[[2-[[4-(4-ethanoylpiperazin-1-yl)-2-methoxy-phenyl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]phenyl]prop-2-enamide
Human
9066
0.52
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