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Searching for structures with analogs of
Tamnorzatinib
.
Search results (13 entries covering 9 PDB structures)
#
Kinase
Family
Group
PDB
Chain
(Alternate) Model
Orthosteric ligand
Organism
Details
Similarity (MFP)
File
MET
Met
TK
3u6h
A
B
n-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophenyl}-1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1h-pyrazole-4-carboxamide
Human
2965
0.45
MET
Met
TK
3u6h
A
A
n-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophenyl}-1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1h-pyrazole-4-carboxamide
Human
2996
0.45
KDR
VEGFR
TK
3b8q
A
n-(4-chlorophenyl)-6-[(6,7-dimethoxyquinolin-4-yl)oxy]naphthalene-1-carboxamide
Human
5332
0.48
KDR
VEGFR
TK
3b8q
B
n-(4-chlorophenyl)-6-[(6,7-dimethoxyquinolin-4-yl)oxy]naphthalene-1-carboxamide
Human
5319
0.48
KDR
VEGFR
TK
3b8r
B
n-cyclopropyl-6-[(6,7-dimethoxyquinolin-4-yl)oxy]naphthalene-1-carboxamide
Human
5341
0.45
KDR
VEGFR
TK
3b8r
A
n-cyclopropyl-6-[(6,7-dimethoxyquinolin-4-yl)oxy]naphthalene-1-carboxamide
Human
5327
0.45
KDR
VEGFR
TK
3u6j
A
n-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophenyl}-1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1h-pyrazole-4-carboxamide
Human
5318
0.45
SYK
Syk
TK
3tuc
A
1-benzyl-n-{5-[(6,7-dimethoxyquinolin-4-yl)oxy]pyridin-2-yl}-2-oxo-1,2-dihydropyridine-3-carboxamide
Human
1195
0.61
SYK
Syk
TK
3tub
A
1-{5-[(6,7-dimethoxyquinolin-4-yl)oxy]pyridin-2-yl}-3-[(1r,2s)-2-phenylcyclopropyl]urea
Human
1179
0.57
FGFR1
FGFR
TK
4rwl
B
6-({7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl}oxy)-n-methylnaphthalene-1-carboxamide
Human
3596
0.45
EIF2AK3 (PEK)
PEK
Other
4x7h
A
B
n-{5-[(6,7-dimethoxyquinolin-4-yl)oxy]pyridin-2-yl}-1-methyl-3-oxo-2-phenyl-5-(pyridin-4-yl)-2,3-dihydro-1h-pyrazole-4-carboxamide
Human
7240
0.61
EIF2AK3 (PEK)
PEK
Other
4x7h
A
A
n-{5-[(6,7-dimethoxyquinolin-4-yl)oxy]pyridin-2-yl}-1-methyl-3-oxo-2-phenyl-5-(pyridin-4-yl)-2,3-dihydro-1h-pyrazole-4-carboxamide
Human
7247
0.61
MET
Met
TK
3vw8
A
n-({4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}carbamothioyl)-2-phenylacetamide
Human
2985
0.43
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Tamnorzatinib
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