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Searching for structures with analogs of
Taletrectinib
.
Search results (13 entries covering 7 PDB structures)
#
Kinase
Family
Group
PDB
Chain
(Alternate) Model
Orthosteric ligand
Organism
Details
Similarity (MFP)
File
DAPK3
DAPK
CAMK
3bqr
A
B
4-(6-{[(1r)-1-(hydroxymethyl)propyl]amino}imidazo[1,2-b]pyridazin-3-yl)benzoic acid
Human
386
0.40
DAPK3
DAPK
CAMK
3bqr
A
A
4-(6-{[(1r)-1-(hydroxymethyl)propyl]amino}imidazo[1,2-b]pyridazin-3-yl)benzoic acid
Human
380
0.40
ERN1 (IRE1)
IRE
Other
4z7h
A
2-methoxy-4-[6-(propan-2-ylamino)imidazo[1,2-b]pyridazin-3-yl]benzamide
Human
1794
0.45
PIM1
PIM
CAMK
2c3i
B
A
1-(3-{6-[(cyclopropylmethyl)amino]imidazo[1,2-b]pyridazin-3-yl}phenyl)ethanone
Human
2348
0.40
ALK
ALK
TK
6edl
A
A
n-[(1s)-1-(2,4-difluorophenyl)ethyl]-3-(5-methyl-1h-pyrazol-3-yl)imidazo[1,2-b]pyridazin-6-amine
Human
11267
0.43
PIM1
PIM
CAMK
2c3i
B
B
1-(3-{6-[(cyclopropylmethyl)amino]imidazo[1,2-b]pyridazin-3-yl}phenyl)ethanone
Human
2374
0.40
ERN1 (IRE1)
IRE
Other
4z7h
B
2-methoxy-4-[6-(propan-2-ylamino)imidazo[1,2-b]pyridazin-3-yl]benzamide
Human
1801
0.45
CLK1
CLK
CMGC
6yta
A
B
1-(3-{6-[(cyclopropylmethyl)amino]imidazo[1,2-b]pyridazin-3-yl}phenyl)ethanone
Human
12417
0.40
ACVR1 (ALK2)
STKR
TKL
4dym
A
1-(3-{6-[(cyclopropylmethyl)amino]imidazo[1,2-b]pyridazin-3-yl}phenyl)ethanone
Human
1509
0.40
ALK
ALK
TK
6edl
A
B
n-[(1s)-1-(2,4-difluorophenyl)ethyl]-3-(5-methyl-1h-pyrazol-3-yl)imidazo[1,2-b]pyridazin-6-amine
Human
11265
0.43
HASPIN (Haspin)
Haspin
Other
3f2n
A
B
(2s)-2-{[3-(3-aminophenyl)imidazo[1,2-b]pyridazin-6-yl]amino}-3-methylbutan-1-ol
Human
3813
0.48
HASPIN (Haspin)
Haspin
Other
3f2n
A
A
(2s)-2-{[3-(3-aminophenyl)imidazo[1,2-b]pyridazin-6-yl]amino}-3-methylbutan-1-ol
Human
3803
0.48
CLK1
CLK
CMGC
6yta
A
A
1-(3-{6-[(cyclopropylmethyl)amino]imidazo[1,2-b]pyridazin-3-yl}phenyl)ethanone
Human
12423
0.40
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Taletrectinib
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