KLIFS - the structural kinase database

Searching for structures with analogs of -.

Search results (14 entries covering 6 PDB structures)

Kinase	Family	Group	PDB	Chain	(Alternate) Model	Orthosteric ligand	Organism	Details	Similarity (MFP)
RIPK1	RIPK	TKL	5tx5	A	A	gsk2982772	Human	8214	1.00
RIPK1	RIPK	TKL	6nw2	A	B	(5r)-5-methyl-n-[(3s)-5-methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-4,5,6,7-tetrahydro-2h-indazole-3-carboxamide	Human	11041	0.54
RIPK1	RIPK	TKL	5tx5	A	B	gsk2982772	Human	8217	1.00
RIPK1	RIPK	TKL	6rln	B		~{n}-[(3~{s})-7,9-bis(fluoranyl)-2-oxidanylidene-1,3,4,5-tetrahydro-1-benzazepin-3-yl]-3-(phenylmethyl)-1~{h}-1,2,4-triazole-5-carboxamide	Human	11382	0.52
RIPK1	RIPK	TKL	5tx5	B	A	gsk2982772	Human	8216	1.00
RIPK1	RIPK	TKL	5hx6	B		5-benzyl-n-[(3s)-5-methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-1,2-oxazole-3-carboxamide	Human	6418	0.66
RIPK1	RIPK	TKL	6nw2	A	A	(5r)-5-methyl-n-[(3s)-5-methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-4,5,6,7-tetrahydro-2h-indazole-3-carboxamide	Human	11040	0.54
RIPK1	RIPK	TKL	7fd0	A		n-[(3s)-5-methyl-7-[2-(oxan-4-yl)ethynyl]-4-oxidanylidene-2,3-dihydro-1,5-benzoxazepin-3-yl]-5-(phenylmethyl)-4h-1,2,4-triazole-3-carboxamide	Human	14070	0.52
RIPK1	RIPK	TKL	5hx6	A		5-benzyl-n-[(3s)-5-methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-1,2-oxazole-3-carboxamide	Human	6417	0.66
RIPK1	RIPK	TKL	6nw2	B	A	(5r)-5-methyl-n-[(3s)-5-methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-4,5,6,7-tetrahydro-2h-indazole-3-carboxamide	Human	11039	0.54
RIPK1	RIPK	TKL	5tx5	B	B	gsk2982772	Human	8215	1.00
RIPK1	RIPK	TKL	6rln	A		~{n}-[(3~{s})-7,9-bis(fluoranyl)-2-oxidanylidene-1,3,4,5-tetrahydro-1-benzazepin-3-yl]-3-(phenylmethyl)-1~{h}-1,2,4-triazole-5-carboxamide	Human	11383	0.52
RIPK1	RIPK	TKL	6nw2	B	B	(5r)-5-methyl-n-[(3s)-5-methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-4,5,6,7-tetrahydro-2h-indazole-3-carboxamide	Human	11043	0.54
RIPK1	RIPK	TKL	7fcz	A		n-[(3s)-7-(2-cyclopropylethynyl)-5-methyl-4-oxidanylidene-2,3-dihydro-1,5-benzoxazepin-3-yl]-5-(phenylmethyl)-4h-1,2,4-triazole-3-carboxamide	Human	14071	0.55