Searching for structures with analogs of -.
Search results (13 entries covering 5 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | Similarity (MFP) | File |
|---|---|---|---|---|---|---|---|---|---|---|---|
| JAK3 | JakA | TK | 6hzv | D | A | 3-[7-(2-hydroxyethyl)-9-(oxan-4-yl)-8-oxidanylidene-purin-2-yl]imidazo[1,2-a]pyridine-6-carbonitrile | Human | 11749 | 0.45 | ||
| JAK3 | JakA | TK | 6hzv | A | A | 3-[7-(2-hydroxyethyl)-9-(oxan-4-yl)-8-oxidanylidene-purin-2-yl]imidazo[1,2-a]pyridine-6-carbonitrile | Human | 11756 | 0.45 | ||
| JAK3 | JakA | TK | 6hzv | B | B | 3-[7-(2-hydroxyethyl)-9-(oxan-4-yl)-8-oxidanylidene-purin-2-yl]imidazo[1,2-a]pyridine-6-carbonitrile | Human | 11754 | 0.45 | ||
| JAK3 | JakA | TK | 6hzv | B | A | 3-[7-(2-hydroxyethyl)-9-(oxan-4-yl)-8-oxidanylidene-purin-2-yl]imidazo[1,2-a]pyridine-6-carbonitrile | Human | 11753 | 0.45 | ||
| JAK3 | JakA | TK | 6hzv | C | B | 3-[7-(2-hydroxyethyl)-9-(oxan-4-yl)-8-oxidanylidene-purin-2-yl]imidazo[1,2-a]pyridine-6-carbonitrile | Human | 11755 | 0.45 | ||
| NTRK1 (TRKA) | Trk | TK | 4yps | A | 4-{6-[(3r)-3-(3-fluorophenyl)morpholin-4-yl]imidazo[1,2-b]pyridazin-3-yl}benzonitrile | Human | 3615 | 0.41 | |||
| MKNK2 (MNK2) | MAPKAPK | CAMK | 8p9b | A | 4-[6-(4-morpholin-4-ylcarbonylphenyl)imidazo[1,2-a]pyridin-3-yl]benzenecarbonitrile | Human | 15296 | 1.00 | |||
| JAK3 | JakA | TK | 6hzv | C | A | 3-[7-(2-hydroxyethyl)-9-(oxan-4-yl)-8-oxidanylidene-purin-2-yl]imidazo[1,2-a]pyridine-6-carbonitrile | Human | 11752 | 0.45 | ||
| JAK3 | JakA | TK | 6hzv | A | B | 3-[7-(2-hydroxyethyl)-9-(oxan-4-yl)-8-oxidanylidene-purin-2-yl]imidazo[1,2-a]pyridine-6-carbonitrile | Human | 11751 | 0.45 | ||
| JAK3 | JakA | TK | 6hzv | D | B | 3-[7-(2-hydroxyethyl)-9-(oxan-4-yl)-8-oxidanylidene-purin-2-yl]imidazo[1,2-a]pyridine-6-carbonitrile | Human | 11750 | 0.45 | ||
| TTK | TTK | Other | 6tn9 | A | B | [4-[[6-(3,5-dimethyl-4-oxidanyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]phenyl]-morpholin-4-yl-methanone | Human | 12269 | 0.45 | ||
| TTK | TTK | Other | 6tn9 | A | A | [4-[[6-(3,5-dimethyl-4-oxidanyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]phenyl]-morpholin-4-yl-methanone | Human | 12271 | 0.45 | ||
| JAK3 | JakA | TK | 8rpn | A | 3-[4-[[(3~{r})-1-(2-cyanoethanoyl)piperidin-3-yl]amino]pyrimidin-2-yl]imidazo[1,2-a]pyridine-6-carbonitrile | Human | 15523 | 0.44 |
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