KLIFS - the structural kinase database

Searching for structures with analogs of -.

Search results (12 entries covering 4 PDB structures)

Kinase	Family	Group	PDB	Chain	(Alternate) Model	Orthosteric ligand	Organism	Details	Similarity (MFP)
JAK3	JakA	TK	6hzv	D	A	3-[7-(2-hydroxyethyl)-9-(oxan-4-yl)-8-oxidanylidene-purin-2-yl]imidazo[1,2-a]pyridine-6-carbonitrile	Human	11749	0.45
JAK3	JakA	TK	6hzv	A	A	3-[7-(2-hydroxyethyl)-9-(oxan-4-yl)-8-oxidanylidene-purin-2-yl]imidazo[1,2-a]pyridine-6-carbonitrile	Human	11756	0.45
JAK3	JakA	TK	6hzv	B	B	3-[7-(2-hydroxyethyl)-9-(oxan-4-yl)-8-oxidanylidene-purin-2-yl]imidazo[1,2-a]pyridine-6-carbonitrile	Human	11754	0.45
JAK3	JakA	TK	6hzv	C	A	3-[7-(2-hydroxyethyl)-9-(oxan-4-yl)-8-oxidanylidene-purin-2-yl]imidazo[1,2-a]pyridine-6-carbonitrile	Human	11752	0.45
JAK3	JakA	TK	6hzv	D	B	3-[7-(2-hydroxyethyl)-9-(oxan-4-yl)-8-oxidanylidene-purin-2-yl]imidazo[1,2-a]pyridine-6-carbonitrile	Human	11750	0.45
JAK3	JakA	TK	6hzv	B	A	3-[7-(2-hydroxyethyl)-9-(oxan-4-yl)-8-oxidanylidene-purin-2-yl]imidazo[1,2-a]pyridine-6-carbonitrile	Human	11753	0.45
JAK3	JakA	TK	6hzv	C	B	3-[7-(2-hydroxyethyl)-9-(oxan-4-yl)-8-oxidanylidene-purin-2-yl]imidazo[1,2-a]pyridine-6-carbonitrile	Human	11755	0.45
NTRK1 (TRKA)	Trk	TK	4yps	A		4-{6-[(3r)-3-(3-fluorophenyl)morpholin-4-yl]imidazo[1,2-b]pyridazin-3-yl}benzonitrile	Human	3615	0.41
MKNK2 (MNK2)	MAPKAPK	CAMK	8p9b	A		4-[6-(4-morpholin-4-ylcarbonylphenyl)imidazo[1,2-a]pyridin-3-yl]benzenecarbonitrile	Human	15296	1.00
JAK3	JakA	TK	6hzv	A	B	3-[7-(2-hydroxyethyl)-9-(oxan-4-yl)-8-oxidanylidene-purin-2-yl]imidazo[1,2-a]pyridine-6-carbonitrile	Human	11751	0.45
TTK	TTK	Other	6tn9	A	B	[4-[[6-(3,5-dimethyl-4-oxidanyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]phenyl]-morpholin-4-yl-methanone	Human	12269	0.45
TTK	TTK	Other	6tn9	A	A	[4-[[6-(3,5-dimethyl-4-oxidanyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]phenyl]-morpholin-4-yl-methanone	Human	12271	0.45