Searching for structures with analogs of Eclitasertib.

Search results (12 entries covering 5 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetailsSimilarity (MFP)File
RIPK1RIPKTKL5tx5AAgsk2982772Human82140.57
RIPK1RIPKTKL6nw2AB(5r)-5-methyl-n-[(3s)-5-methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-4,5,6,7-tetrahydro-2h-indazole-3-carboxamideHuman110410.41
RIPK1RIPKTKL5tx5ABgsk2982772Human82170.57
RIPK1RIPKTKL5tx5BAgsk2982772Human82160.57
RIPK1RIPKTKL5hx6B5-benzyl-n-[(3s)-5-methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-1,2-oxazole-3-carboxamideHuman64180.49
RIPK1RIPKTKL7fd0An-[(3s)-5-methyl-7-[2-(oxan-4-yl)ethynyl]-4-oxidanylidene-2,3-dihydro-1,5-benzoxazepin-3-yl]-5-(phenylmethyl)-4h-1,2,4-triazole-3-carboxamideHuman140700.44
RIPK1RIPKTKL5hx6A5-benzyl-n-[(3s)-5-methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-1,2-oxazole-3-carboxamideHuman64170.49
RIPK1RIPKTKL6nw2BA(5r)-5-methyl-n-[(3s)-5-methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-4,5,6,7-tetrahydro-2h-indazole-3-carboxamideHuman110390.41
RIPK1RIPKTKL5tx5BBgsk2982772Human82150.57
RIPK1RIPKTKL7fczAn-[(3s)-7-(2-cyclopropylethynyl)-5-methyl-4-oxidanylidene-2,3-dihydro-1,5-benzoxazepin-3-yl]-5-(phenylmethyl)-4h-1,2,4-triazole-3-carboxamideHuman140710.45
RIPK1RIPKTKL6nw2BB(5r)-5-methyl-n-[(3s)-5-methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-4,5,6,7-tetrahydro-2h-indazole-3-carboxamideHuman110430.41
RIPK1RIPKTKL6nw2AA(5r)-5-methyl-n-[(3s)-5-methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-4,5,6,7-tetrahydro-2h-indazole-3-carboxamideHuman110400.41