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Searching for structures with analogs of
Zimlovisertib
.
Search results (8 entries covering 3 PDB structures)
#
Kinase
Family
Group
PDB
Chain
(Alternate) Model
Orthosteric ligand
Organism
Details
Similarity (MFP)
File
IRAK4
IRAK
TKL
5uit
A
1-{[(2s)-5-oxopyrrolidin-2-yl]methoxy}-7-[(propan-2-yl)oxy]isoquinoline-6-carboxamide
Human
7606
0.52
IRAK4
IRAK
TKL
5uit
B
1-{[(2s)-5-oxopyrrolidin-2-yl]methoxy}-7-[(propan-2-yl)oxy]isoquinoline-6-carboxamide
Human
7597
0.52
IRAK4
IRAK
TKL
8wtf
A
A
1-{[(2s,3s,4s)-3-ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide
Human
14960
1.00
IRAK4
IRAK
TKL
8wtf
A
B
1-{[(2s,3s,4s)-3-ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide
Human
14963
1.00
IRAK4
IRAK
TKL
5uiu
A
A
1-{[(2s,3s,4s)-3-ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide
Human
7603
1.00
IRAK4
IRAK
TKL
5uiu
B
B
1-{[(2s,3s,4s)-3-ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide
Human
7609
1.00
IRAK4
IRAK
TKL
5uiu
B
A
1-{[(2s,3s,4s)-3-ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide
Human
7607
1.00
IRAK4
IRAK
TKL
5uiu
A
B
1-{[(2s,3s,4s)-3-ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide
Human
7615
1.00
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Zimlovisertib
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