Searching for structures with analogs of -.
Search results (12 entries covering 5 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | Similarity (MFP) | File |
|---|---|---|---|---|---|---|---|---|---|---|---|
| CDK2 | CDK | CMGC | 2i40 | A | B | 5-[5,6-bis(methyloxy)-1h-benzimidazol-1-yl]-3-{[1-(2-chlorophenyl)ethyl]oxy}-2-thiophenecarboxamide | Human | 4470 | 0.54 | ||
| CDK2 | CDK | CMGC | 2i40 | A | A | 5-[5,6-bis(methyloxy)-1h-benzimidazol-1-yl]-3-{[1-(2-chlorophenyl)ethyl]oxy}-2-thiophenecarboxamide | Human | 4363 | 0.54 | ||
| CDK2 | CDK | CMGC | 2i40 | C | A | 5-[5,6-bis(methyloxy)-1h-benzimidazol-1-yl]-3-{[1-(2-chlorophenyl)ethyl]oxy}-2-thiophenecarboxamide | Human | 4222 | 0.54 | ||
| NEK2 | NEK | Other | 2xnp | A | B | 4-{5-[(1-methylpiperidin-4-yl)oxy]-1h-benzimidazol-1-yl}-2-{(1r)-1-[2-(trifluoromethyl)phenyl]ethoxy}benzamide | Human | 322 | 0.49 | ||
| CDK2 | CDK | CMGC | 2i40 | C | B | 5-[5,6-bis(methyloxy)-1h-benzimidazol-1-yl]-3-{[1-(2-chlorophenyl)ethyl]oxy}-2-thiophenecarboxamide | Human | 4043 | 0.54 | ||
| NEK2 | NEK | Other | 2xno | A | A | 5-{6-[(1-methylpiperidin-4-yl)oxy]-1h-benzimidazol-1-yl}-3-{[2-(trifluoromethyl)benzyl]oxy}thiophene-2-carboxamide | Human | 319 | 0.56 | ||
| NEK2 | NEK | Other | 2xnm | A | B | 5-{6-[(1-methylpiperidin-4-yl)oxy]-1h-benzimidazol-1-yl}-3-{(1r)-1-[2-(trifluoromethyl)phenyl]ethoxy}thiophene-2-carboxamide | Human | 324 | 0.73 | ||
| NEK2 | NEK | Other | 2xnn | A | B | 5-(1h-benzimidazol-1-yl)-3-{(1r)-1-[2-(trifluoromethyl)phenyl]ethoxy}thiophene-2-carboxamide | Human | 308 | 0.73 | ||
| NEK2 | NEK | Other | 2xnn | A | A | 5-(1h-benzimidazol-1-yl)-3-{(1r)-1-[2-(trifluoromethyl)phenyl]ethoxy}thiophene-2-carboxamide | Human | 303 | 0.73 | ||
| NEK2 | NEK | Other | 2xno | A | B | 5-{6-[(1-methylpiperidin-4-yl)oxy]-1h-benzimidazol-1-yl}-3-{[2-(trifluoromethyl)benzyl]oxy}thiophene-2-carboxamide | Human | 313 | 0.56 | ||
| NEK2 | NEK | Other | 2xnp | A | A | 4-{5-[(1-methylpiperidin-4-yl)oxy]-1h-benzimidazol-1-yl}-2-{(1r)-1-[2-(trifluoromethyl)phenyl]ethoxy}benzamide | Human | 328 | 0.49 | ||
| NEK2 | NEK | Other | 2xnm | A | A | 5-{6-[(1-methylpiperidin-4-yl)oxy]-1h-benzimidazol-1-yl}-3-{(1r)-1-[2-(trifluoromethyl)phenyl]ethoxy}thiophene-2-carboxamide | Human | 306 | 0.73 |
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