Searching for structures with analogs of -.

Search results (183 entries covering 91 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetailsSimilarity (MFP)File
SYKSykTK1xbcAAstaurosporineHuman11650.73
DYRK1ADYRKCMGC4nctApkc412Human37940.54
PIK3CG (p110g)PIKAtypical1e8zAstaurosporineHuman92280.73
CDK2CDKCMGC1pkdA7-hydroxystaurosporineHuman41701.00
PRKAA2 (AMPKa2)CAMKLCAMK6b1uCAstaurosporineHuman98470.73
Prkaa1 (AMPKa1)CAMKLCAMK5ufuAstaurosporineMouse75900.73
PIM1PIMCAMK1yhsAstaurosporineHuman24440.73
FESFerTK3cd3AAstaurosporineHuman28140.73
RPS6KA1 (RSK3)RSKAGC2z7rAstaurosporineHuman27770.73
MAP3K5STE11STE4bf2AstaurosporineHuman47430.73
JAK3JakATK1yvjAA1,2,3,4-tetrahydrogen-staurosporineHuman4600.62
MAP3K5STE11STE2clqBBstaurosporineHuman47320.73
EGFREGFRTK2itqAA1,2,3,4-tetrahydrogen staurosporineHuman8130.57
STK32A (YANK1)YANKAGC4fr4BAstaurosporineHuman46920.73
PRKAA1 (AMPKa1)CAMKLCAMK4rerAstaurosporineHuman1210.73
PRKAA1 (AMPKa1)CAMKLCAMK4rewAstaurosporineHuman1240.73
PRKAA1 (AMPKa1)CAMKLCAMK6c9gAstaurosporineHuman107150.73
PRKAA1 (AMPKa1)CAMKLCAMK6c9hAstaurosporineHuman107140.73
PRKAA1 (AMPKa1)CAMKLCAMK6c9jAstaurosporineHuman107170.73
PRKAA1 (AMPKa1)CAMKLCAMK6c9fAstaurosporineHuman107160.73
EGFREGFRTK2ituAA1,2,3,4-tetrahydrogen staurosporineHuman7790.57
EGFREGFRTK2itwAA1,2,3,4-tetrahydrogen staurosporineHuman8170.57
CDK2CDKCMGC4ez7AstaurosporineHuman42400.73
JAK3JakATK1yvjAB1,2,3,4-tetrahydrogen-staurosporineHuman4510.62
STK24 (MST3)STE20STE3ckxAstaurosporineHuman55990.73
ZAP70SykTK1u59AAstaurosporineHuman27340.73
RIPK2RIPKTKL5ng2BAstaurosporineHuman80530.73
RIPK2RIPKTKL5ng2BBstaurosporineHuman80520.73
RIPK2RIPKTKL5ng2AAstaurosporineHuman80500.73
RIPK2RIPKTKL5ng2ABstaurosporineHuman80560.73
MKNK2 (MNK2)MAPKAPKCAMK2hw7AstaurosporineHuman7640.73
CDK2CDKCMGC7nvqAstaurosporineHuman136270.73
MASTLMASTAGC5lohBAstaurosporineHuman70880.73
MASTLMASTAGC5lohBBstaurosporineHuman70870.73
MASTLMASTAGC5lohABstaurosporineHuman70850.73
MASTLMASTAGC5lohAAstaurosporineHuman70860.73
FESFerTK3bkbAAstaurosporineHuman28100.73
FESFerTK3cblAAstaurosporineHuman28080.73
FESFerTK3cd3ABstaurosporineHuman28150.73
FESFerTK3bkbACstaurosporineHuman28120.73
FESFerTK3cblABstaurosporineHuman28110.73
FESFerTK3bkbABstaurosporineHuman28130.73
ERN1 (IRE1)IREOther4yzcABstaurosporineHuman62320.73
ZAP70SykTK1u59ABstaurosporineHuman27330.73
ERN1 (IRE1)IREOther4yzcBAstaurosporineHuman62270.73
SYKSykTK1xbcABstaurosporineHuman12070.73
ERN1 (IRE1)IREOther4yzcBBstaurosporineHuman62310.73
ERN1 (IRE1)IREOther4yzcAAstaurosporineHuman62350.73
DYRK1ADYRKCMGC4nctCpkc412Human37790.54
PKN1PKNAGC4otgAAlestaurtinibHuman5480.40
STK32A (YANK1)YANKAGC4fr4ABstaurosporineHuman46900.73
STK32A (YANK1)YANKAGC4fr4CAstaurosporineHuman46840.73
CHEK1 (CHK1)CAMKLCAMK7akoABstaurosporineHuman134950.73
CHEK1 (CHK1)CAMKLCAMK5oorAstaurosporineHuman86030.73
STK32A (YANK1)YANKAGC4fr4EBstaurosporineHuman46850.73
CHEK1 (CHK1)CAMKLCAMK1nvsArel-(9r,12s)-9,10,11,12-tetrahydro-9,12-epoxy-1h-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-1,3(2h)-dioneHuman15910.42
CHEK1 (CHK1)CAMKLCAMK1nvrAstaurosporineHuman15850.73
CHEK1 (CHK1)CAMKLCAMK7akoBBstaurosporineHuman134960.73
CHEK1 (CHK1)CAMKLCAMK1nvqA7-hydroxystaurosporineHuman16421.00
PRKAA2 (AMPKa2)CAMKLCAMK7myjA(5s,6r,7r,9r,13cr,14r,16as)-6-methoxy-5-methyl-7-(methylamino)-6,7,8,9,14,15,16,16a-octahydro-5h,13ch-5,9-epoxy-4b,9a,15-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacen-14-olHuman142730.57
MELKCAMKLCAMK5m5aAAk-252aHuman87350.47
GSK3BGSKCMGC1q3dBstaurosporineHuman7520.73
CSKCskTK1bygAstaurosporineHuman29430.73
LCKSrcTK1qpdAstaurosporineHuman22670.73
LCKSrcTK1qpjAstaurosporineHuman22830.73
MAP3K5STE11STE2clqAAstaurosporineHuman47400.73
LYNSrcTK3a4oXstaurosporineHuman18120.73
MAPKAPK2MAPKAPKCAMK1nxkAstaurosporineHuman13420.73
EGFREGFRTK2ituAB1,2,3,4-tetrahydrogen staurosporineHuman8590.57
EGFREGFRTK2itqAB1,2,3,4-tetrahydrogen staurosporineHuman8460.57
EGFREGFRTK2itwAB1,2,3,4-tetrahydrogen staurosporineHuman9140.57
MAP2K6STE7STE3fmeAstaurosporineHuman12310.73
PRKAA2 (AMPKa2)CAMKLCAMK5ezvCAstaurosporineHuman64300.73
PRKAA2 (AMPKa2)CAMKLCAMK4cffCstaurosporineHuman1900.73
PRKAA2 (AMPKa2)CAMKLCAMK4cffAstaurosporineHuman1910.73
PRKAA2 (AMPKa2)CAMKLCAMK6b1uAAstaurosporineHuman98480.73
PRKAA2 (AMPKa2)CAMKLCAMK4zhxCB(5s,6r,7r,9r,13cr,14r,16as)-6-methoxy-5-methyl-7-(methylamino)-6,7,8,9,14,15,16,16a-octahydro-5h,13ch-5,9-epoxy-4b,9a,15-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacen-14-olHuman64230.57
PRKAA2 (AMPKa2)CAMKLCAMK5isoAstaurosporineHuman79810.73
PRKAA2 (AMPKa2)CAMKLCAMK4cfeCstaurosporineHuman1920.73
PRKAA2 (AMPKa2)CAMKLCAMK6b1uCBstaurosporineHuman98500.73
PRKAA2 (AMPKa2)CAMKLCAMK5isoCstaurosporineHuman79800.73
PRKAA2 (AMPKa2)CAMKLCAMK5ezvCBstaurosporineHuman64260.73
PRKAA2 (AMPKa2)CAMKLCAMK5ezvAAstaurosporineHuman64240.73
PRKAA2 (AMPKa2)CAMKLCAMK6b2eAstaurosporineHuman98510.73
PRKAA2 (AMPKa2)CAMKLCAMK4zhxAB(5s,6r,7r,9r,13cr,14r,16as)-6-methoxy-5-methyl-7-(methylamino)-6,7,8,9,14,15,16,16a-octahydro-5h,13ch-5,9-epoxy-4b,9a,15-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacen-14-olHuman64290.57
AAK1NAKOther4wsqBBk-252aHuman38350.47
AAK1NAKOther4wsqAAk-252aHuman38340.47
AAK1NAKOther4wsqBAk-252aHuman38330.47
AAK1NAKOther4wsqABk-252aHuman38360.47
TGFBR2 (TGFbR2)STKRTKL5e8yAstaurosporineHuman66270.73
EPHB4 (EphB4)EphTK3zewAAstaurosporineHuman3730.73
EPHB4 (EphB4)EphTK3zewBAstaurosporineHuman3510.73
EPHB4 (EphB4)EphTK2yn8AstaurosporineHuman3520.73
EPHB4 (EphB4)EphTK3zewABstaurosporineHuman3770.73
EPHB4 (EphB4)EphTK2yn8BstaurosporineHuman3490.73
EPHB4 (EphB4)EphTK3zewBBstaurosporineHuman3570.73
DYRK1ADYRKCMGC4nctBpkc412Human37430.54
DYRK1ADYRKCMGC4nctDpkc412Human37510.54
STK24 (MST3)STE20STE4qmyAstaurosporineHuman55920.73
MELKCAMKLCAMK5m5aABk-252aHuman87330.47
STK16 (MPSK1)NAKOther2bujBstaurosporineHuman22300.73
STK16 (MPSK1)NAKOther2bujAstaurosporineHuman22290.73
CDK2CDKCMGC1aq1AstaurosporineHuman42670.73
CDK2CDKCMGC1pkdC7-hydroxystaurosporineHuman39731.00
CDK2CDKCMGC4erwAstaurosporineHuman43700.73
IRAK4IRAKTKL2oicBstaurosporineHuman17520.73
IRAK4IRAKTKL4u97BstaurosporineHuman17420.73
IRAK4IRAKTKL4u97AstaurosporineHuman17540.73
IRAK4IRAKTKL4u9aAstaurosporineHuman17510.73
IRAK4IRAKTKL2oicDstaurosporineHuman17550.73
IRAK4IRAKTKL4u9aBstaurosporineHuman17920.73
IRAK4IRAKTKL2nryCAstaurosporineHuman17790.73
IRAK4IRAKTKL2nryDBstaurosporineHuman17460.73
ABL1AblTK2hz4B1,2,3,4-tetrahydrogen-staurosporineHuman10580.62
IRAK4IRAKTKL2oicAstaurosporineHuman17390.73
IRAK4IRAKTKL2nryCBstaurosporineHuman17500.73
IRAK4IRAKTKL2nryBBstaurosporineHuman17720.73
IRAK4IRAKTKL2nryABstaurosporineHuman17770.73
IRAK4IRAKTKL2oicCstaurosporineHuman17340.73
GSK3BGSKCMGC1q3dAstaurosporineHuman7050.73
IRAK4IRAKTKL2nryBAstaurosporineHuman17580.73
IRAK4IRAKTKL2nryDAstaurosporineHuman17890.73
IRAK4IRAKTKL2nryAAstaurosporineHuman17530.73
ALKALKTK3lcsAAstaurosporineHuman53810.73
ALKALKTK3lcsABstaurosporineHuman53760.73
PDPK1 (PDK1)PDK1AGC1okzA7-hydroxystaurosporineHuman32091.00
PDPK1 (PDK1)PDK1AGC1okyAAstaurosporineHuman31640.73
PDPK1 (PDK1)PDK1AGC1okyABstaurosporineHuman31950.73
LIMK1LISKTKL3s95BBstaurosporineHuman12470.73
LIMK1LISKTKL3s95BAstaurosporineHuman12450.73
LIMK1LISKTKL3s95AAstaurosporineHuman12460.73
LIMK1LISKTKL3s95ABstaurosporineHuman12480.73
PRKCQ (PKCt)PKCAGC1xjdAstaurosporineHuman53570.73
ITKTecTK1sm2AstaurosporineHuman740.73
ITKTecTK1snuAstaurosporineHuman820.73
ITKTecTK1sm2BstaurosporineHuman730.73
ITKTecTK1snuBstaurosporineHuman330.73
CHEK1 (CHK1)CAMKLCAMK7akoAAstaurosporineHuman134900.73
CHEK1 (CHK1)CAMKLCAMK7akoBAstaurosporineHuman134920.73
PKN1PKNAGC4otgABlestaurtinibHuman5490.40
MAP3K5STE11STE2clqBAstaurosporineHuman47550.73
MAP3K5STE11STE2clqABstaurosporineHuman47360.73
MAP3K5STE11STE4bf2BstaurosporineHuman47450.73
STK32A (YANK1)YANKAGC4fr4BBstaurosporineHuman46950.73
STK32A (YANK1)YANKAGC4fr4FBstaurosporineHuman46860.73
CSKCskTK3d7tAstaurosporineHuman29410.73
DAPK1DAPKCAMK1wvyAstaurosporineHuman56610.73
STK32A (YANK1)YANKAGC4fr4AAstaurosporineHuman46930.73
STK32A (YANK1)YANKAGC4fr4EAstaurosporineHuman46890.73
STK32A (YANK1)YANKAGC4fr4CBstaurosporineHuman46940.73
STK32A (YANK1)YANKAGC4fr4DAstaurosporineHuman46880.73
STK32A (YANK1)YANKAGC4fr4FAstaurosporineHuman46910.73
STK32A (YANK1)YANKAGC4fr4DBstaurosporineHuman46870.73
MAPKAPK2MAPKAPKCAMK1nxkCstaurosporineHuman13120.73
MAPKAPK2MAPKAPKCAMK1nxkDstaurosporineHuman13340.73
MAPKAPK2MAPKAPKCAMK2pzyCstaurosporineHuman12790.73
MAPKAPK2MAPKAPKCAMK1nxkBstaurosporineHuman12920.73
TTKTTKOther3hmoAstaurosporineHuman47070.73
PAK1STE20STE2hy81(5s,6r,7r,9r)-12-hydroxy-6-methoxy-5-methyl-7-(methylamino)-6,7,8,9-tetrahydro-5h,14h-5,9-epoxy-4b,9a,15-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacen-14-oneHuman1720.66
IKBKB (IKKb)IKKOther4kikBBk-252aHuman2930.47
IKBKB (IKKb)IKKOther4kikAAk-252aHuman2900.47
IKBKB (IKKb)IKKOther4kikABk-252aHuman2880.47
IKBKB (IKKb)IKKOther4kikBAk-252aHuman2950.47
FYNSrcTK2dq7XstaurosporineHuman19410.73
TGFBR1 (TGFbR1)STKRTKL5e8wAAstaurosporineHuman66110.73
TGFBR1 (TGFbR1)STKRTKL5e8xAAstaurosporineHuman66150.73
RPS6KB1 (p70S6K)RSKAGC3a61AstaurosporineHuman18460.73
RPS6KB1 (p70S6K)RSKAGC3a62AstaurosporineHuman18670.73
TGFBR1 (TGFbR1)STKRTKL5e8xABstaurosporineHuman66170.73
TGFBR1 (TGFbR1)STKRTKL5e8wABstaurosporineHuman66140.73
RPS6KB1 (p70S6K)RSKAGC4rloBstaurosporineHuman72200.73
RPS6KB1 (p70S6K)RSKAGC3a60BstaurosporineHuman18560.73
RPS6KB1 (p70S6K)RSKAGC3a60AstaurosporineHuman18520.73
PAK4STE20STE5vedAstaurosporineHuman85700.73
METMetTK1r0pAk-252aHuman29910.47
MAP2K1STE7STE3eqfAk-252aHuman33170.47
PRKAA2 (AMPKa2)CAMKLCAMK6b1uABstaurosporineHuman98490.73
PRKAA2 (AMPKa2)CAMKLCAMK4cfeAstaurosporineHuman1950.73
PRKAA2 (AMPKa2)CAMKLCAMK4zhxCA(5s,6r,7r,9r,13cr,14r,16as)-6-methoxy-5-methyl-7-(methylamino)-6,7,8,9,14,15,16,16a-octahydro-5h,13ch-5,9-epoxy-4b,9a,15-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacen-14-olHuman64270.57
PRKAA2 (AMPKa2)CAMKLCAMK4zhxAA(5s,6r,7r,9r,13cr,14r,16as)-6-methoxy-5-methyl-7-(methylamino)-6,7,8,9,14,15,16,16a-octahydro-5h,13ch-5,9-epoxy-4b,9a,15-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacen-14-olHuman64250.57
PRKAA2 (AMPKa2)CAMKLCAMK5ezvABstaurosporineHuman64280.73
Ripk4 (ANKRD3)RIPKTKL5wnlAstaurosporineMouse98910.73
Ripk4 (ANKRD3)RIPKTKL5wnjAlestaurtinibMouse98930.40