Searching for structures with analogs of -.

Search results (40 entries covering 16 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetailsSimilarity (MFP)File
CAMKK2 (CaMKK2)CAMKKOther6cmjBB2-(2-methylpropyl)-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acidHuman97850.64
CAMKK2 (CaMKK2)CAMKKOther5uy6A2-cyclopentyl-4-(5-phenylfuro[2,3-b]pyridin-3-yl)benzoic acidHuman79820.66
CAMKK2 (CaMKK2)CAMKKOther5uyjAB2-cyclopentyl-4-(7-methoxyquinolin-4-yl)benzoic acidHuman75590.46
CAMKK2 (CaMKK2)CAMKKOther5uyjAA2-cyclopentyl-4-(7-methoxyquinolin-4-yl)benzoic acidHuman75600.46
CAMKK2 (CaMKK2)CAMKKOther6cmjAB2-(2-methylpropyl)-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acidHuman97830.64
CAMKK2 (CaMKK2)CAMKKOther6cmjBA2-(2-methylpropyl)-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acidHuman97860.64
CAMKK2 (CaMKK2)CAMKKOther6bkuA2-cyclopentyl-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acidHuman86871.00
CAMKK2 (CaMKK2)CAMKKOther6cmjAA2-(2-methylpropyl)-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acidHuman97840.64
Abl1 (ABL1)AblTK2qohB5-[3-(2-methoxyphenyl)-1h-pyrrolo[2,3-b]pyridin-5-yl]-n,n-dimethylpyridine-3-carboxamideMouse57160.41
JAK3JakATK7apfAB3-[3-(propanoylamino)phenyl]-1~{h}-pyrrolo[2,3-b]pyridine-5-carboxamideHuman131300.42
JAK3JakATK7apfBB3-[3-(propanoylamino)phenyl]-1~{h}-pyrrolo[2,3-b]pyridine-5-carboxamideHuman131320.42
JAK3JakATK7apfBA3-[3-(propanoylamino)phenyl]-1~{h}-pyrrolo[2,3-b]pyridine-5-carboxamideHuman131370.42
JAK3JakATK7apfAA3-[3-(propanoylamino)phenyl]-1~{h}-pyrrolo[2,3-b]pyridine-5-carboxamideHuman131410.42
CAMKK1 (CaMKK1)CAMKKOther6cd6CB2-cyclopentyl-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acidHuman97151.00
CAMKK1 (CaMKK1)CAMKKOther6cd6BB2-cyclopentyl-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acidHuman97131.00
CAMKK1 (CaMKK1)CAMKKOther6cd6CA2-cyclopentyl-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acidHuman97111.00
CAMKK1 (CaMKK1)CAMKKOther6cd6AB2-cyclopentyl-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acidHuman97141.00
CAMKK1 (CaMKK1)CAMKKOther6cd6BA2-cyclopentyl-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acidHuman97091.00
DYRK1ADYRKCMGC6ej4A3-(3-pyridin-3-yl-1~{h}-pyrrolo[2,3-b]pyridin-5-yl)anilineHuman105200.45
DYRK1ADYRKCMGC6eifA4-(3-pyridin-3-yl-1~{h}-pyrrolo[2,3-b]pyridin-5-yl)benzenesulfonamideHuman105340.48
DYRK1ADYRKCMGC6eifC4-(3-pyridin-3-yl-1~{h}-pyrrolo[2,3-b]pyridin-5-yl)benzenesulfonamideHuman105250.48
ABL1AblTK7cc2A[4-[5-[5-(dimethylcarbamoyl)pyridin-3-yl]-1h-pyrrolo[2,3-b]pyridin-3-yl]-2-methyl-phenyl]boronic acidHuman136200.46
CHEK1 (CHK1)CAMKLCAMK1zysAn-{5-[4-(4-methylpiperazin-1-yl)phenyl]-1h-pyrrolo[2,3-b]pyridin-3-yl}nicotinamideHuman16550.43
DYRK1ADYRKCMGC6ej4D3-(3-pyridin-3-yl-1~{h}-pyrrolo[2,3-b]pyridin-5-yl)anilineHuman105450.45
CAMKK1 (CaMKK1)CAMKKOther6cd6AA2-cyclopentyl-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acidHuman97161.00
DYRK1ADYRKCMGC6ej4B3-(3-pyridin-3-yl-1~{h}-pyrrolo[2,3-b]pyridin-5-yl)anilineHuman105230.45
DYRK1ADYRKCMGC6ej4C3-(3-pyridin-3-yl-1~{h}-pyrrolo[2,3-b]pyridin-5-yl)anilineHuman105190.45
DYRK1ADYRKCMGC6eifB4-(3-pyridin-3-yl-1~{h}-pyrrolo[2,3-b]pyridin-5-yl)benzenesulfonamideHuman105440.48
DYRK1ADYRKCMGC6eifD4-(3-pyridin-3-yl-1~{h}-pyrrolo[2,3-b]pyridin-5-yl)benzenesulfonamideHuman105320.48
LIMK1LISKTKL7atsAn-[3-[5-(4-chlorophenyl)-1h-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]benzenesulfonamideHuman131640.40
SGK1SGKAGC3hdnA[4-(5-naphthalen-2-yl-1h-pyrrolo[2,3-b]pyridin-3-yl)phenyl]acetic acidHuman32700.48
SGK1SGKAGC3hdmA4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acidHuman32710.62
INSRInsRTK3etaBB1-(3-{5-[4-(aminomethyl)phenyl]-1h-pyrrolo[2,3-b]pyridin-3-yl}phenyl)-3-(2-phenoxyphenyl)ureaHuman6000.43
INSRInsRTK3etaAA1-(3-{5-[4-(aminomethyl)phenyl]-1h-pyrrolo[2,3-b]pyridin-3-yl}phenyl)-3-(2-phenoxyphenyl)ureaHuman5900.43
INSRInsRTK3etaAB1-(3-{5-[4-(aminomethyl)phenyl]-1h-pyrrolo[2,3-b]pyridin-3-yl}phenyl)-3-(2-phenoxyphenyl)ureaHuman5790.43
INSRInsRTK3etaBA1-(3-{5-[4-(aminomethyl)phenyl]-1h-pyrrolo[2,3-b]pyridin-3-yl}phenyl)-3-(2-phenoxyphenyl)ureaHuman5880.43
CAMKK1 (CaMKK1)CAMKKOther6cd6DA2-cyclopentyl-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acidHuman97101.00
CAMKK1 (CaMKK1)CAMKKOther6cd6DB2-cyclopentyl-4-(5-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)benzoic acidHuman97081.00
Abl1 (ABL1)AblTK2z60A5-[3-(2-methoxyphenyl)-1h-pyrrolo[2,3-b]pyridin-5-yl]-n,n-dimethylpyridine-3-carboxamideMouse57350.41
Abl1 (ABL1)AblTK2qohA5-[3-(2-methoxyphenyl)-1h-pyrrolo[2,3-b]pyridin-5-yl]-n,n-dimethylpyridine-3-carboxamideMouse57070.41