| SYK | Syk | TK | 4dfl | A | | 3-amino-6-{3-[(methylsulfonyl)amino]phenyl}-n-(piperidin-4-ylmethyl)pyrazine-2-carboxamide | Human | 1152 | 0.45 | |
| GSK3B | GSK | CMGC | 6hk4 | A | B | 3-azanyl-6-(4-morpholin-4-ylsulfonylphenyl)-~{n}-pyridin-3-yl-pyrazine-2-carboxamide | Human | 11423 | 0.54 | |
| PIK3CG (p110g) | PIK | Atypical | 4anw | A | A | 3-amino-6-{4-chloro-3-[(2,3-difluorophenyl)sulfamoyl]phenyl}-n-methylpyrazine-2-carboxamide | Human | 9174 | 0.45 | |
| PIK3CG (p110g) | PIK | Atypical | 4anu | A | | 3-amino-n-methyl-6-[3-(1h-tetrazol-5-yl)phenyl]pyrazine-2-carboxamide | Human | 9162 | 0.43 | |
| GSK3B | GSK | CMGC | 6hk3 | B | B | 3-azanyl-~{n}-(2-methoxyphenyl)-6-[4-(4-methylpiperazin-1-yl)sulfonylphenyl]pyrazine-2-carboxamide | Human | 11424 | 0.53 | |
| GSK3B | GSK | CMGC | 6hk4 | B | B | 3-azanyl-6-(4-morpholin-4-ylsulfonylphenyl)-~{n}-pyridin-3-yl-pyrazine-2-carboxamide | Human | 11427 | 0.54 | |
| GSK3B | GSK | CMGC | 4ach | A | | 3-amino-n-(3-methoxypropyl)-6-{4-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}pyrazine-2-carboxamide | Human | 653 | 0.45 | |
| GSK3B | GSK | CMGC | 4acd | A | | 3-amino-6-{4-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-n-pyridin-3-ylpyrazine-2-carboxamide | Human | 723 | 0.56 | |
| GSK3B | GSK | CMGC | 4ach | B | | 3-amino-n-(3-methoxypropyl)-6-{4-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}pyrazine-2-carboxamide | Human | 702 | 0.45 | |
| CDK2 | CDK | CMGC | 4acm | A | A | 3-amino-6-(4-{[2-(dimethylamino)ethyl]sulfamoyl}phenyl)-n-pyridin-3-ylpyrazine-2-carboxamide | Human | 4247 | 0.55 | |
| CDK2 | CDK | CMGC | 2vtl | A | | n-phenyl-1h-pyrazole-3-carboxamide | Human | 3870 | 0.40 | |
| KIT | PDGFR | TK | 7khk | A | | 4,5-dimethyl-n-(2-phenyl-1h-pyrrolo[2,3-b]pyridin-5-yl)-1h-pyrazole-3-carboxamide | Human | 13787 | 0.40 | |
| PIK3CG (p110g) | PIK | Atypical | 4anw | A | B | 3-amino-6-{4-chloro-3-[(2,3-difluorophenyl)sulfamoyl]phenyl}-n-methylpyrazine-2-carboxamide | Human | 9175 | 0.45 | |
| CDK2 | CDK | CMGC | 2vti | A | | n-(4-sulfamoylphenyl)-1h-indazole-3-carboxamide | Human | 4177 | 0.40 | |
| MAP4K4 (HGK) | STE20 | STE | 5di1 | A | | 4-{6-amino-5-[4-(methylsulfonyl)phenyl]pyridin-3-yl}phenol | Human | 6354 | 0.43 | |
| GSK3B | GSK | CMGC | 6hk4 | A | A | 3-azanyl-6-(4-morpholin-4-ylsulfonylphenyl)-~{n}-pyridin-3-yl-pyrazine-2-carboxamide | Human | 11429 | 0.54 | |
| GSK3B | GSK | CMGC | 4acc | B | | 3-amino-6-(4-{[2-(dimethylamino)ethyl]sulfamoyl}phenyl)-n-pyridin-3-ylpyrazine-2-carboxamide | Human | 669 | 0.55 | |
| GSK3B | GSK | CMGC | 6hk4 | B | A | 3-azanyl-6-(4-morpholin-4-ylsulfonylphenyl)-~{n}-pyridin-3-yl-pyrazine-2-carboxamide | Human | 11430 | 0.54 | |
| GSK3B | GSK | CMGC | 6hk3 | B | A | 3-azanyl-~{n}-(2-methoxyphenyl)-6-[4-(4-methylpiperazin-1-yl)sulfonylphenyl]pyrazine-2-carboxamide | Human | 11422 | 0.53 | |
| GSK3B | GSK | CMGC | 6hk7 | A | | 3-azanyl-~{n}-(2-methoxyethyl)-6-[4-(4-methylpiperazin-1-yl)sulfonylphenyl]pyrazine-2-carboxamide | Human | 11428 | 0.45 | |
| GSK3B | GSK | CMGC | 4acd | B | | 3-amino-6-{4-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-n-pyridin-3-ylpyrazine-2-carboxamide | Human | 692 | 0.56 | |
| GSK3B | GSK | CMGC | 6hk3 | A | A | 3-azanyl-~{n}-(2-methoxyphenyl)-6-[4-(4-methylpiperazin-1-yl)sulfonylphenyl]pyrazine-2-carboxamide | Human | 11425 | 0.53 | |
| CDK2 | CDK | CMGC | 4acm | A | B | 3-amino-6-(4-{[2-(dimethylamino)ethyl]sulfamoyl}phenyl)-n-pyridin-3-ylpyrazine-2-carboxamide | Human | 3983 | 0.55 | |
| GSK3B | GSK | CMGC | 6hk3 | A | B | 3-azanyl-~{n}-(2-methoxyphenyl)-6-[4-(4-methylpiperazin-1-yl)sulfonylphenyl]pyrazine-2-carboxamide | Human | 11426 | 0.53 | |
| GSK3B | GSK | CMGC | 4acc | A | | 3-amino-6-(4-{[2-(dimethylamino)ethyl]sulfamoyl}phenyl)-n-pyridin-3-ylpyrazine-2-carboxamide | Human | 704 | 0.55 | |
| PIK3CA (p110a) | PIK | Atypical | 5ul1 | A | B | 3-amino-6-(4-{[(2s)-1-(dimethylamino)propan-2-yl]sulfonyl}phenyl)-n-phenylpyrazine-2-carboxamide | Human | 9308 | 0.69 | |
| PIK3CA (p110a) | PIK | Atypical | 5ul1 | A | A | 3-amino-6-(4-{[(2s)-1-(dimethylamino)propan-2-yl]sulfonyl}phenyl)-n-phenylpyrazine-2-carboxamide | Human | 9316 | 0.69 | |
Match: