Searching for structures with analogs of Acalisib.
Search results (4 entries covering 4 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | Similarity (MFP) | File |
|---|---|---|---|---|---|---|---|---|---|---|---|
| PIK3CG (p110g) | PIK | Atypical | 5eds | A | 4-azanyl-6-[[(1~{s})-1-[6-fluoranyl-1-(3-methylsulfonylphenyl)benzimidazol-2-yl]ethyl]amino]pyrimidine-5-carbonitrile | Human | 9208 | 0.43 | |||
| PIK3CG (p110g) | PIK | Atypical | 4wwn | A | n-{(1s)-1-[7-fluoro-2-(pyridin-2-yl)quinolin-3-yl]ethyl}-9h-purin-6-amine | Human | 9226 | 0.40 | |||
| Pik3cd (p110d) | PIK | Atypical | 5i6u | A | 2-[(1s)-1-({6-amino-5-[(1h-pyrazol-4-yl)ethynyl]pyrimidin-4-yl}amino)ethyl]-5-chloro-3-phenylquinazolin-4(3h)-one | Mouse | 9370 | 0.44 | |||
| Pik3cd (p110d) | PIK | Atypical | 4xe0 | A | 5-fluoro-3-phenyl-2-[(1s)-1-(7h-purin-6-ylamino)propyl]quinazolin-4(3h)-one | Mouse | 9368 | 0.65 |
Acalisib
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