Searching for structures with analogs of -.

Search results (18 entries covering 8 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetailsSimilarity (MFP)File
PIM1PIMCAMK2c3iBA1-(3-{6-[(cyclopropylmethyl)amino]imidazo[1,2-b]pyridazin-3-yl}phenyl)ethanoneHuman23480.60
PIM1PIMCAMK4a7cAn-(piperidin-4-ylmethyl)-3-[3-(trifluoromethyloxy)phenyl]-[1,2,3]triazolo[4,5-b]pyridin-5-amineHuman23210.40
PIM1PIMCAMK2c3iBB1-(3-{6-[(cyclopropylmethyl)amino]imidazo[1,2-b]pyridazin-3-yl}phenyl)ethanoneHuman23740.60
CLK1CLKCMGC6ytaAA1-(3-{6-[(cyclopropylmethyl)amino]imidazo[1,2-b]pyridazin-3-yl}phenyl)ethanoneHuman124230.60
CLK1CLKCMGC6ytaAB1-(3-{6-[(cyclopropylmethyl)amino]imidazo[1,2-b]pyridazin-3-yl}phenyl)ethanoneHuman124170.60
HASPIN (Haspin)HaspinOther3f2nAB(2s)-2-{[3-(3-aminophenyl)imidazo[1,2-b]pyridazin-6-yl]amino}-3-methylbutan-1-olHuman38130.40
ACVR1 (ALK2)STKRTKL4dymA1-(3-{6-[(cyclopropylmethyl)amino]imidazo[1,2-b]pyridazin-3-yl}phenyl)ethanoneHuman15090.60
ACVR1 (ALK2)STKRTKL3oomAA1-{3-[6-(tetrahydro-2h-pyran-4-ylamino)imidazo[1,2-b]pyridazin-3-yl]phenyl}ethanoneHuman15170.42
ACVR1 (ALK2)STKRTKL3oomAB1-{3-[6-(tetrahydro-2h-pyran-4-ylamino)imidazo[1,2-b]pyridazin-3-yl]phenyl}ethanoneHuman15180.42
NTRK3 (TRKC)TrkTK4ymjAA4-[6-(benzylamino)imidazo[1,2-b]pyridazin-3-yl]benzonitrileHuman1010.40
NTRK3 (TRKC)TrkTK4ymjAB4-[6-(benzylamino)imidazo[1,2-b]pyridazin-3-yl]benzonitrileHuman980.40
NTRK3 (TRKC)TrkTK4ymjBA4-[6-(benzylamino)imidazo[1,2-b]pyridazin-3-yl]benzonitrileHuman1000.40
NTRK3 (TRKC)TrkTK4ymjBB4-[6-(benzylamino)imidazo[1,2-b]pyridazin-3-yl]benzonitrileHuman990.40
DYRK1ADYRKCMGC6s11AB6-pyridin-4-yl-3-[3-(trifluoromethyloxy)phenyl]imidazo[1,2-b]pyridazineHuman113640.54
DYRK1ADYRKCMGC6s11AA6-pyridin-4-yl-3-[3-(trifluoromethyloxy)phenyl]imidazo[1,2-b]pyridazineHuman113610.54
DYRK1ADYRKCMGC6s11BB6-pyridin-4-yl-3-[3-(trifluoromethyloxy)phenyl]imidazo[1,2-b]pyridazineHuman113720.54
DYRK1ADYRKCMGC6s11BA6-pyridin-4-yl-3-[3-(trifluoromethyloxy)phenyl]imidazo[1,2-b]pyridazineHuman113780.54
HASPIN (Haspin)HaspinOther3f2nAA(2s)-2-{[3-(3-aminophenyl)imidazo[1,2-b]pyridazin-6-yl]amino}-3-methylbutan-1-olHuman38030.40