| PIM1 | PIM | CAMK | 2c3i | B | A | 1-(3-{6-[(cyclopropylmethyl)amino]imidazo[1,2-b]pyridazin-3-yl}phenyl)ethanone | Human | 2348 | 0.60 | |
| NTRK3 (TRKC) | Trk | TK | 4ymj | B | A | 4-[6-(benzylamino)imidazo[1,2-b]pyridazin-3-yl]benzonitrile | Human | 100 | 0.40 | |
| PIM1 | PIM | CAMK | 2c3i | B | B | 1-(3-{6-[(cyclopropylmethyl)amino]imidazo[1,2-b]pyridazin-3-yl}phenyl)ethanone | Human | 2374 | 0.60 | |
| PIM1 | PIM | CAMK | 4a7c | A | | n-(piperidin-4-ylmethyl)-3-[3-(trifluoromethyloxy)phenyl]-[1,2,3]triazolo[4,5-b]pyridin-5-amine | Human | 2321 | 0.40 | |
| CLK1 | CLK | CMGC | 6yta | A | B | 1-(3-{6-[(cyclopropylmethyl)amino]imidazo[1,2-b]pyridazin-3-yl}phenyl)ethanone | Human | 12417 | 0.60 | |
| DYRK1A | DYRK | CMGC | 6s11 | A | A | 6-pyridin-4-yl-3-[3-(trifluoromethyloxy)phenyl]imidazo[1,2-b]pyridazine | Human | 11361 | 0.54 | |
| DYRK1A | DYRK | CMGC | 6s11 | B | B | 6-pyridin-4-yl-3-[3-(trifluoromethyloxy)phenyl]imidazo[1,2-b]pyridazine | Human | 11372 | 0.54 | |
| DYRK1A | DYRK | CMGC | 6s11 | B | A | 6-pyridin-4-yl-3-[3-(trifluoromethyloxy)phenyl]imidazo[1,2-b]pyridazine | Human | 11378 | 0.54 | |
| DYRK1A | DYRK | CMGC | 6s11 | A | B | 6-pyridin-4-yl-3-[3-(trifluoromethyloxy)phenyl]imidazo[1,2-b]pyridazine | Human | 11364 | 0.54 | |
| ACVR1 (ALK2) | STKR | TKL | 4dym | A | | 1-(3-{6-[(cyclopropylmethyl)amino]imidazo[1,2-b]pyridazin-3-yl}phenyl)ethanone | Human | 1509 | 0.60 | |
| ACVR1 (ALK2) | STKR | TKL | 3oom | A | A | 1-{3-[6-(tetrahydro-2h-pyran-4-ylamino)imidazo[1,2-b]pyridazin-3-yl]phenyl}ethanone | Human | 1517 | 0.42 | |
| ACVR1 (ALK2) | STKR | TKL | 3oom | A | B | 1-{3-[6-(tetrahydro-2h-pyran-4-ylamino)imidazo[1,2-b]pyridazin-3-yl]phenyl}ethanone | Human | 1518 | 0.42 | |
| HASPIN (Haspin) | Haspin | Other | 3f2n | A | B | (2s)-2-{[3-(3-aminophenyl)imidazo[1,2-b]pyridazin-6-yl]amino}-3-methylbutan-1-ol | Human | 3813 | 0.40 | |
| HASPIN (Haspin) | Haspin | Other | 3f2n | A | A | (2s)-2-{[3-(3-aminophenyl)imidazo[1,2-b]pyridazin-6-yl]amino}-3-methylbutan-1-ol | Human | 3803 | 0.40 | |
| NTRK3 (TRKC) | Trk | TK | 4ymj | A | A | 4-[6-(benzylamino)imidazo[1,2-b]pyridazin-3-yl]benzonitrile | Human | 101 | 0.40 | |
| NTRK3 (TRKC) | Trk | TK | 4ymj | A | B | 4-[6-(benzylamino)imidazo[1,2-b]pyridazin-3-yl]benzonitrile | Human | 98 | 0.40 | |
| NTRK3 (TRKC) | Trk | TK | 4ymj | B | B | 4-[6-(benzylamino)imidazo[1,2-b]pyridazin-3-yl]benzonitrile | Human | 99 | 0.40 | |
| CLK1 | CLK | CMGC | 6yta | A | A | 1-(3-{6-[(cyclopropylmethyl)amino]imidazo[1,2-b]pyridazin-3-yl}phenyl)ethanone | Human | 12423 | 0.60 | |