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Searching for structures with analogs of
-
.
Search results (8 entries covering 3 PDB structures)
#
Kinase
Family
Group
PDB
Chain
(Alternate) Model
Orthosteric ligand
Organism
Details
Similarity (MFP)
File
BRAF
RAF
TKL
5c9c
B
B
1-(3,3-dimethylbutyl)-3-{2-fluoro-4-methyl-5-[7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl]phenyl}urea
Human
3119
1.00
BRAF
RAF
TKL
5c9c
B
A
1-(3,3-dimethylbutyl)-3-{2-fluoro-4-methyl-5-[7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl]phenyl}urea
Human
3138
1.00
BRAF
RAF
TKL
7k0v
A
A
n-(3,3-dimethylbutyl)-n'-{2-fluoro-5-[(5-fluoro-3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]-4-methylphenyl}urea
Human
13617
0.46
BRAF
RAF
TKL
7k0v
A
B
n-(3,3-dimethylbutyl)-n'-{2-fluoro-5-[(5-fluoro-3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]-4-methylphenyl}urea
Human
13616
0.46
BRAF
RAF
TKL
5c9c
A
A
1-(3,3-dimethylbutyl)-3-{2-fluoro-4-methyl-5-[7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl]phenyl}urea
Human
3123
1.00
EPHA2 (EphA2)
Eph
TK
8xpv
A
B
1-(3,3-dimethylbutyl)-3-{2-fluoro-4-methyl-5-[7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl]phenyl}urea
Human
15135
1.00
EPHA2 (EphA2)
Eph
TK
8xpv
A
A
1-(3,3-dimethylbutyl)-3-{2-fluoro-4-methyl-5-[7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl]phenyl}urea
Human
15134
1.00
BRAF
RAF
TKL
5c9c
A
B
1-(3,3-dimethylbutyl)-3-{2-fluoro-4-methyl-5-[7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl]phenyl}urea
Human
3074
1.00
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