| BRAF | RAF | TKL | 5jsm | C | B | n,n'-{ethane-1,2-diylbis[oxyethane-2,1-diyloxy-4,1-phenylene-1h-pyrrolo[2,3-b]pyridine-5,3-diylcarbonyl(2,4-difluoro-3,1-phenylene)]}di(propane-1-sulfonamide) | Human | 7063 | 0.52 | |
| BRAF | RAF | TKL | 4fk3 | A | | n-{2,4-difluoro-3-[(5-pyridin-3-yl-1h-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]phenyl}ethanesulfonamide | Human | 3118 | 0.53 | |
| BRAF | RAF | TKL | 4rzv | A | | n-(3-{[5-(4-chlorophenyl)-1h-pyrrolo[2,3-b]pyridin-3-yl]carbonyl}-2,4-difluorophenyl)propane-1-sulfonamide | Human | 6944 | 0.55 | |
| BRAF | RAF | TKL | 4wo5 | B | | n-{3-[(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl}propane-1-sulfonamide | Human | 3143 | 0.49 | |
| BRAF | RAF | TKL | 5jsm | C | A | n,n'-{ethane-1,2-diylbis[oxyethane-2,1-diyloxy-4,1-phenylene-1h-pyrrolo[2,3-b]pyridine-5,3-diylcarbonyl(2,4-difluoro-3,1-phenylene)]}di(propane-1-sulfonamide) | Human | 7059 | 0.52 | |
| BRAF | RAF | TKL | 4xv1 | A | | n'-(3-{[5-(2-cyclopropylpyrimidin-5-yl)-1h-pyrrolo[2,3-b]pyridin-3-yl]carbonyl}-2,4-difluorophenyl)-n-ethyl-n-methylsulfuric diamide | Human | 6214 | 0.72 | |
| BRAF | RAF | TKL | 5jrq | B | | (3-{[dihydroxy(propyl)-lambda~4~-sulfanyl]amino}-2,6-difluorophenyl)[5-(4-methoxyphenyl)-1h-pyrrolo[2,3-b]pyridin-3-yl]methanone | Human | 7054 | 0.51 | |
| BRAF | RAF | TKL | 4rzv | B | | n-(3-{[5-(4-chlorophenyl)-1h-pyrrolo[2,3-b]pyridin-3-yl]carbonyl}-2,4-difluorophenyl)propane-1-sulfonamide | Human | 6941 | 0.55 | |
| BRAF | RAF | TKL | 4xv9 | A | A | n-{3-[(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl}-4-(trifluoromethyl)benzenesulfonamide | Human | 6220 | 0.47 | |
| BRAF | RAF | TKL | 4xv9 | A | B | n-{3-[(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl}-4-(trifluoromethyl)benzenesulfonamide | Human | 6215 | 0.47 | |
| BRAF | RAF | TKL | 5jsm | B | B | n,n'-{ethane-1,2-diylbis[oxyethane-2,1-diyloxy-4,1-phenylene-1h-pyrrolo[2,3-b]pyridine-5,3-diylcarbonyl(2,4-difluoro-3,1-phenylene)]}di(propane-1-sulfonamide) | Human | 7062 | 0.52 | |
| BRAF | RAF | TKL | 5jt2 | A | | 2,2'-oxybis[n-({4-[3-(3-{[dihydroxy(propyl)-lambda~4~-sulfanyl]amino}-2,6-difluorobenzene-1-carbonyl)-1h-pyrrolo[2,3-b]pyridin-5-yl]phenyl}methyl)acetamide] | Human | 7065 | 0.49 | |
| BRAF | RAF | TKL | 3og7 | A | | n-(3-{[5-(4-chlorophenyl)-1h-pyrrolo[2,3-b]pyridin-3-yl]carbonyl}-2,4-difluorophenyl)propane-1-sulfonamide | Human | 3113 | 0.55 | |
| PAK1 | STE20 | STE | 5kbr | A | | (4-chlorophenyl)-[5-(1-piperidin-4-ylpyrazol-4-yl)-1~{h}-pyrrolo[2,3-b]pyridin-3-yl]methanone | Human | 7080 | 0.43 | |
| PAK1 | STE20 | STE | 5kbr | B | | (4-chlorophenyl)-[5-(1-piperidin-4-ylpyrazol-4-yl)-1~{h}-pyrrolo[2,3-b]pyridin-3-yl]methanone | Human | 7079 | 0.43 | |
| MAP3K20 (ZAK) | MLK | TKL | 5hes | A | B | n-(3-{[5-(4-chlorophenyl)-1h-pyrrolo[2,3-b]pyridin-3-yl]carbonyl}-2,4-difluorophenyl)propane-1-sulfonamide | Human | 6458 | 0.55 | |
| MAP3K20 (ZAK) | MLK | TKL | 5hes | B | A | n-(3-{[5-(4-chlorophenyl)-1h-pyrrolo[2,3-b]pyridin-3-yl]carbonyl}-2,4-difluorophenyl)propane-1-sulfonamide | Human | 6459 | 0.55 | |
| MAP3K20 (ZAK) | MLK | TKL | 5hes | A | A | n-(3-{[5-(4-chlorophenyl)-1h-pyrrolo[2,3-b]pyridin-3-yl]carbonyl}-2,4-difluorophenyl)propane-1-sulfonamide | Human | 6460 | 0.55 | |
| MAP3K20 (ZAK) | MLK | TKL | 5hes | B | B | n-(3-{[5-(4-chlorophenyl)-1h-pyrrolo[2,3-b]pyridin-3-yl]carbonyl}-2,4-difluorophenyl)propane-1-sulfonamide | Human | 6457 | 0.55 | |
| LIMK1 | LISK | TKL | 7ats | A | | n-[3-[5-(4-chlorophenyl)-1h-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]benzenesulfonamide | Human | 13164 | 0.55 | |
| BRAF | RAF | TKL | 5jsm | B | A | n,n'-{ethane-1,2-diylbis[oxyethane-2,1-diyloxy-4,1-phenylene-1h-pyrrolo[2,3-b]pyridine-5,3-diylcarbonyl(2,4-difluoro-3,1-phenylene)]}di(propane-1-sulfonamide) | Human | 7060 | 0.52 | |
| BRAF | RAF | TKL | 4wo5 | A | | n-{3-[(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl}propane-1-sulfonamide | Human | 3079 | 0.49 | |
| BRAF | RAF | TKL | 5jrq | A | | (3-{[dihydroxy(propyl)-lambda~4~-sulfanyl]amino}-2,6-difluorophenyl)[5-(4-methoxyphenyl)-1h-pyrrolo[2,3-b]pyridin-3-yl]methanone | Human | 7061 | 0.51 | |
| BRAF | RAF | TKL | 3c4c | A | | n-{3-[(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl}propane-1-sulfonamide | Human | 3115 | 0.49 | |
| BRAF | RAF | TKL | 5jt2 | C | | 2,2'-oxybis[n-({4-[3-(3-{[dihydroxy(propyl)-lambda~4~-sulfanyl]amino}-2,6-difluorobenzene-1-carbonyl)-1h-pyrrolo[2,3-b]pyridin-5-yl]phenyl}methyl)acetamide] | Human | 7064 | 0.49 | |
| BRAF | RAF | TKL | 3c4c | B | | n-{3-[(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl}propane-1-sulfonamide | Human | 3063 | 0.49 | |
Match: