KLIFS - the structural kinase database

Searching for structures with analogs of -.

Search results (13 entries covering 6 PDB structures)

Kinase	Family	Group	PDB	Chain	(Alternate) Model	Orthosteric ligand	Organism	Details	Similarity (MFP)
AURKA (AurA)	Aur	Other	3w16	A		4-[(5-methyl-1h-pyrazol-3-yl)amino]-2-phenylphthalazin-1(2h)-one	Human	2012	0.46
JAK2	JakA	TK	2xa4	B	B	5-chloro-n2-[(1s)-1-(5-fluoropyrimidin-2-yl)ethyl]-n4-(5-methyl-1h-pyrazol-3-yl)pyrimidine-2,4-diamine	Human	3707	0.42
JAK2	JakA	TK	2xa4	A	A	5-chloro-n2-[(1s)-1-(5-fluoropyrimidin-2-yl)ethyl]-n4-(5-methyl-1h-pyrazol-3-yl)pyrimidine-2,4-diamine	Human	3664	0.42
JAK2	JakA	TK	2xa4	A	B	5-chloro-n2-[(1s)-1-(5-fluoropyrimidin-2-yl)ethyl]-n4-(5-methyl-1h-pyrazol-3-yl)pyrimidine-2,4-diamine	Human	3623	0.42
ULK1	ULK	Other	4wno	A	B	n~2~-(4-aminophenyl)-n~4~-(5-cyclopropyl-1h-pyrazol-3-yl)quinazoline-2,4-diamine	Human	1876	0.41
JAK2	JakA	TK	2xa4	B	A	5-chloro-n2-[(1s)-1-(5-fluoropyrimidin-2-yl)ethyl]-n4-(5-methyl-1h-pyrazol-3-yl)pyrimidine-2,4-diamine	Human	3628	0.42
ULK1	ULK	Other	4wno	A	A	n~2~-(4-aminophenyl)-n~4~-(5-cyclopropyl-1h-pyrazol-3-yl)quinazoline-2,4-diamine	Human	1881	0.41
CAMK1D (CaMK1d)	CAMK1	CAMK	2jc6	A	B	n-(5-methyl-1h-pyrazol-3-yl)-2-phenylquinazolin-4-amine	Human	4830	0.61
AURKA (AurA)	Aur	Other	5zan	A		7-(4-methylpiperazin-1-yl)-n-(5-methyl-1h-pyrazol-3-yl)-2-[(e)-2-phenylethenyl]quinazolin-4-amine	Human	10898	0.43
AURKA (AurA)	Aur	Other	3p9j	A		4-[(5-methyl-1h-pyrazol-3-yl)amino]-2-phenylphthalazin-1(2h)-one	Human	2003	0.46
CAMK1D (CaMK1d)	CAMK1	CAMK	2jc6	C	A	n-(5-methyl-1h-pyrazol-3-yl)-2-phenylquinazolin-4-amine	Human	4832	0.61
CAMK1D (CaMK1d)	CAMK1	CAMK	2jc6	C	B	n-(5-methyl-1h-pyrazol-3-yl)-2-phenylquinazolin-4-amine	Human	4831	0.61
CAMK1D (CaMK1d)	CAMK1	CAMK	2jc6	A	A	n-(5-methyl-1h-pyrazol-3-yl)-2-phenylquinazolin-4-amine	Human	4829	0.61